Simonetta Vespucci
Simonetta Vespucci (née Cattaneo; 1453 – 26 April 1476), nicknamed ''la bella Simonetta'', was an Italian noblewoman from Genoa, the wife of Marco Vespucci of Florence and the cousin-in-law of Amerigo Vespucci. She was known as the greatest beauty of her age in Italy, and was allegedly the model for many paintings by Sandro Botticelli, Piero di Cosimo, and other Florentine painters. Some art historians have taken issue with these attributions, which the Victorian critic John Ruskin has been blamed for promulgating. Biography Early life and marriage Simonetta Vespucci was born Simonetta Cattaneo 1453 in a part of the Republic of Genoa that is now in the Italian region of Liguria. A more precise location for her birthplace is unknown: possibly the city of Genoa, or perhaps either Portovenere or Fezzano. The Florentine poet Politian wrote that her home was "in that stern Ligurian district up above the seacoast, where angry Neptune beats against the rocks ... There, like ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Piero Di Cosimo
Piero di Cosimo (2 January 1462 – 12 April 1522), also known as Piero di Lorenzo, was an Italian painter of the Renaissance. He is most famous for the mythological and allegorical subjects he painted in the late Quattrocento; he is said to have abandoned these to return to religious subjects under the influence of Savonarola, the preacher who exercised a huge sway in Florence in the 1490s, and had a similar effect on Botticelli. The High Renaissance style of the new century had little influence on him, and he retained the straightforward realism of his figures, which combines with an often whimsical treatment of his subjects to create the distinctive mood of his works. Vasari has many stories of his eccentricity, and the mythological subjects have an individual and quirky fascination. He trained under Cosimo Rosselli, whose daughter he married, and assisted him in his Sistine Chapel frescos. He was also influenced by Early Netherlandish painting, and busy landscapes feat ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
House Of Medici
The House of Medici ( , ) was an Italian banking family and political dynasty that first began to gather prominence under Cosimo de' Medici, in the Republic of Florence during the first half of the 15th century. The family originated in the Mugello region of Tuscany, and prospered gradually until it was able to fund the Medici Bank. This bank was the largest in Europe during the 15th century and facilitated the Medicis' rise to political power in Florence, although they officially remained citizens rather than monarchs until the 16th century. The Medici produced four popes of the Catholic Church— Pope Leo X (1513–1521), Pope Clement VII (1523–1534), Pope Pius IV (1559–1565) and Pope Leo XI (1605)—and two queens of France— Catherine de' Medici (1547–1559) and Marie de' Medici (1600–1610). In 1532, the family acquired the hereditary title Duke of Florence. In 1569, the duchy was elevated to the Grand Duchy of Tuscany after territorial expansion. The Medici ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Growth Hormone
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. A recombinant form of hGH called somatropin (INN) is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency. In the United States, it is only available legally from pharmacies by prescription from a licensed health care provider. In recent years in the United States, some health care providers are prescribing gr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Prolactin
Prolactin (PRL), also known as lactotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. Prolactin is secreted from the pituitary gland in response to eating, mating, estrogen treatment, ovulation and nursing. It is secreted heavily in pulses in between these events. Prolactin plays an essential role in metabolism, regulation of the immune system and pancreatic development. Discovered in non-human animals around 1930 by Oscar Riddle and confirmed in humans in 1970 by Henry Friesen, prolactin is a peptide hormone, encoded by the ''PRL'' gene. In mammals, prolactin is associated with milk production; in fish it is thought to be related to the control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. It has important cell cycle-related functions as a growth-, differentiating- and ant ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Pituitary Adenoma
Pituitary adenomas are tumors that occur in the pituitary gland. Most pituitary tumors are benign, approximately 35% are invasive and just 0.1% to 0.2% are carcinomas.Pituitary Tumors Treatment (PDQ®)–Health Professional Version NIH National Cancer Institute Pituitary adenomas represent from 10% to 25% of all intracranial and the estimated prevalence rate in the general population is approximately 17%. Non-invasive and non-secreting pituitary adenomas are considered to be [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Courtly Love
Courtly love ( oc, fin'amor ; french: amour courtois ) was a medieval European literary conception of love that emphasized nobility and chivalry. Medieval literature is filled with examples of knights setting out on adventures and performing various deeds or services for ladies because of their "courtly love". This kind of love is originally a literary fiction created for the entertainment of the nobility, but as time passed, these ideas about love changed and attracted a larger audience. In the high Middle Ages, a "game of love" developed around these ideas as a set of social practices. "Loving nobly" was considered to be an enriching and improving practice. Courtly love began in the ducal and princely courts of Aquitaine, Provence, Champagne, ducal Burgundy and the Norman Kingdom of Sicily at the end of the eleventh century. In essence, courtly love was an experience between erotic desire and spiritual attainment, "a love at once illicit and morally elevating, passionate ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Routledge
Routledge () is a British multinational publisher. It was founded in 1836 by George Routledge, and specialises in providing academic books, journals and online resources in the fields of the humanities, behavioural science, education, law, and social science. The company publishes approximately 1,800 journals and 5,000 new books each year and their backlist encompasses over 70,000 titles. Routledge is claimed to be the largest global academic publisher within humanities and social sciences. In 1998, Routledge became a subdivision and imprint of its former rival, Taylor & Francis Group (T&F), as a result of a £90-million acquisition deal from Cinven, a venture capital group which had purchased it two years previously for £25 million. Following the merger of Informa and T&F in 2004, Routledge became a publishing unit and major imprint within the Informa "academic publishing" division. Routledge is headquartered in the main T&F office in Milton Park, Abingdon, Oxfords ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Pallas Athene
Athena or Athene, often given the epithet Pallas, is an ancient Greek goddess associated with wisdom, warfare, and handicraft who was later syncretized with the Roman goddess Minerva. Athena was regarded as the patron and protectress of various cities across Greece, particularly the city of Athens, from which she most likely received her name. The Parthenon on the Acropolis of Athens is dedicated to her. Her major symbols include owls, olive trees, snakes, and the Gorgoneion. In art, she is generally depicted wearing a helmet and holding a spear. From her origin as an Aegean palace goddess, Athena was closely associated with the city. She was known as ''Polias'' and ''Poliouchos'' (both derived from '' polis'', meaning "city-state"), and her temples were usually located atop the fortified acropolis in the central part of the city. The Parthenon on the Athenian Acropolis is dedicated to her, along with numerous other temples and monuments. As the patron of craft and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Piazza Santa Croce
Piazza Santa Croce is one of the main plazas or squares located in the central neighbourhood of Florence, in the region of Tuscany, Italy. It is located near Piazza della Signoria and the National Central Library, and takes its name from the Basilica of Santa Croce that overlooks the square. Main buildings Basilica of Santa Croce The most notable features of the basilica are its sixteen chapels, many of them decorated with frescoes by Giotto and his pupils, and its tombs and cenotaphs. It is the burial place of many illustrious Italians, such as Michelangelo, Machiavelli, Enrico Fermi, Galileo, Ugo Foscolo, Guglielmo Marconi, Luigi Cherubini, Leon Battista Alberti, Vittorio Alfieri, Gioacchino Rossini, Lorenzo Ghiberti, Lorenzo Bartolini, Pier Antonio Micheli, Bartolomeo Cristofori, Giovanni Gentile, thus it is known also as the Temple of the Italian Glories (''Tempio dell'Itale Glorie''). Palazzo Cocchi-Serristori On the opposite side to the Basilica of Santa Croce is t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Jousting
Jousting is a martial game or hastilude between two horse riders wielding lances with blunted tips, often as part of a tournament. The primary aim was to replicate a clash of heavy cavalry, with each participant trying to strike the opponent while riding towards him at high speed, breaking the lance on the opponent's shield or jousting armour if possible, or unhorsing him. The joust became an iconic characteristic of the knight in Romantic medievalism. The participants experience close to three and a quarter times their body weight in G-forces when the lances collide with their armour. The term is derived from Old French , ultimately from Latin "to approach, to meet". The word was loaned into Middle English around 1300, when jousting was a very popular sport among the Anglo-Norman knighthood. The synonym tilt (as in tilting at windmills) dates . Jousting is based on the military use of the lance by heavy cavalry. It transformed into a specialized sport during the Late Mi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Villa Di Careggi
The Villa Medici at Careggi is a patrician villa in the hills near Florence, Tuscany, central Italy. History The villa was among the first of a number of Medici villas, notable as the site of the Platonic Academy founded by Cosimo de' Medici, who died at the villa in 1464. Like most villas of Florentine families, the villa remained a working farm that helped render the family self-sufficient. Cosimo's architect there, as elsewhere, was Michelozzo, who remodelled the fortified villa which had something of the character of a castello. Its famous garden is walled about, like a medieval garden, overlooked by the upper-storey loggias, with which Michelozzo cautiously opened up the villa's structure. Michelozzo's Villa Medici in Fiesole has a more outward-looking, Renaissance character. The property was purchased in 1417 by Cosimo de' Medici brother, Lorenzo. At the death of Giovanni di Bicci, Cosimo il Vecchio set about remodelling the beloved villa around its loggia-enclosed ce ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |