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Shigekazu Nagata
is a Japanese biochemist, best known for research on apoptosis, the process of programmed cell death occurring in multi-cellular organisms. Contribution Nagata identified Interferon in 1980 and Granulocyte colony-stimulating factor in 1986. He also identified a death factor (Fas receptor) in 1991 and its ligand ( Fas ligand) in 1993, and elucidated their physiological and pathological roles in apoptosis. Biography Nagata was born in Kanazawa, Japan, and completed his PhD under the supervision of Yoshito Kaziro at the University of Tokyo in 1977. Nagata served as a postdoctoral fellow under Charles Weissmann at University of Zurich, where he worked on sequencing the cDNA of Interferon gene between 1977 and 1981. He was assistant professor at the Institute of Medical Science, the University of Tokyo between 1982 and 1987, and Head of Department of molecular biology at Osaka Bioscience Institute between 1987 and 1998, where Osamu Hayaishi served as president at that tim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kanazawa, Ishikawa
is the capital Cities of Japan, city of Ishikawa Prefecture, Japan. , the city had an estimated population of 466,029 in 203,271 households, and a population density of 990 persons per km2. The total area of the city was . Overview Cityscape File:もてなしドーム３.jpg, Kanazawa Station（2013） File:Omichoichibakan004.jpg, Ōmichō-Market（Ōmichō-Ichiba）（2013） File:Kanazawa view from Utatsuyama Park.jpg, Skyline of Kanazawa City（2017） File:Cityscape at downtown Kanazawa.jpg, Central Business District, CBD of Kanazawa File:Katamachi Crossing.jpg, Downtown of Katamachi Area (2022) Geography Kanazawa is located in north-western Ishikawa Prefecture in the Hokuriku region of Japan and is bordered by the Sea of Japan to the west and Toyama Prefecture to the east. The city sits between the Sai River (Ishikawa), Sai and Asano river, Asano rivers. The eastern portion of the city is dominated by the Japanese Alps. Parts of the city are within the borders of the H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yoshito Kaziro
Yoshito Kaziro (April 18, 1929 – June 29, 2011) was a Japanese biochemical and medical scientist who performed research on the effects and mechanisms of ATP and GTP driven conformational changes in enzymes and intracellular signaling pathways for over 50 years. He is well-known for his research on various signal transduction pathways involving GTP-binding proteins and the mechanism for biotin dependent carboxylation reactions of Coenzyme A (CoA) proteins. Personal life Kaziro was born on April 18, 1929, in Okayama, Japan. He is the son of Nobuyo Kaziro and Kozo Kaziro, a famous researcher of hemoglobin. On August 5, 1950, he married Kuniko Ohkoshi Kaziro. Kaziro and his wife had two children, Shoko Kaziro, his first born named after his research on crystallizing biotin dependent propionyl-CoA carboxylase, and Hisako Kaziro. Over the course of Kaziro's career, he served as a researcher, mentor, and professor while always expressing a warm personality to his peers and student ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Person Of Cultural Merit
is an official Japanese recognition and honor which is awarded annually to select people who have made outstanding cultural contributions. This distinction is intended to play a role as a part of a system of support measures for the promotion of creative activities in Japan. By 1999, 576 people had been selected as Persons of Cultural Merit. Ministry of Education, Culture, Sports, Science and Technology (Japan) ''Culture 2000''./ref> System of recognition The Order of Culture and Persons of Cultural Merit function in tandem to honor those who have contributed to the advancement and development of Japanese culture in a variety of fields, including academia, arts, science and sports. ''Yomiuri Shimbun.'' October 29, 2008. Persons of Cultural Merit [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asahi Prize
The , established in 1929, is an award presented by the Japanese newspaper ''Asahi Shimbun'' and Asahi Shimbun Foundation to honor individuals and groups that have made outstanding accomplishments in the fields of arts and academics and have greatly contributed to the development and progress of Japanese culture and society at large. The Asahi Prize was created to celebrate the 50th anniversary of the foundation of ''Asahi Shimbun''. It is recognized today as one of the most authoritative private awards. Prize winners Past prize winners include the following. Arts * Tsubouchi Shōyō, novelist, 1929 * Taikan Yokoyama, artist, 1933 * Jigoro Kano, founder of judo, 1935 * Shimazaki Toson, novelist, 1935 * Ryōhei Koiso, painter, 1939 * Jun'ichirō Tanizaki, novelist, 1948 * NHK Symphony Orchestra, 1951 * Mashiho Chiri, 1954 * Eiji Yoshikawa, novelist, 1955 * Shikō Munakata, artist, 1964 * Jirō Osaragi, writer, 1964 * Akira Kurosawa, film director, 1965 * Haruko Sugimura, actress ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marburg University
The Philipps University of Marburg (german: Philipps-Universität Marburg) was founded in 1527 by Philip I, Landgrave of Hesse, which makes it one of Germany's oldest universities and the oldest still operating Protestant university in the world. It is now a public university of the state of Hesse, without religious affiliation. The University of Marburg has about 23,500 students and 7,500 employees and is located in Marburg, a town of 76,000 inhabitants, with university buildings dotted in or around the town centre. About 14 per cent of the students are international, the highest percentage in Hesse. It offers an International summer university programme and offers student exchanges through the Erasmus programme. History In 1609, the University of Marburg established the world's first professorship in chemistry. In 2012 it opened the first German interactive chemistry museum, called '. Its experimental course programme is aimed at encouraging young people to pursue careers in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Chemistry
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Medicinal chemistry is a highly interdisciplinary science combining organic chemistry with biochemistry, computational chemistry, pharmacology, molecular biology, statistics, and physical chemistry. Compounds used as medicines are most often organic compounds, which are often divided into the broad classes of small organic molecules (e.g., atorvastatin, fluticasone, clopidogrel) and "biologics" (infliximab, erythropoietin, insulin glargine), the latter of which are most often medicinal preparations of proteins (natural and recombinant antibodi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osamu Hayaishi
, was a Japanese biochemist, physiologist, and military physician. He discovered Oxygenases at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health in 1955. Citing his "outstanding and pioneering contributions to biomedical sciences and enzymology," the Wolf Foundation awarded Hayaishi the 1986 Wolf Prize in Medicine "for his discovery of the oxygenase enzymes and elucidation of their structure and biological importance". Hayaishi was President of International Union of Biochemistry and Molecular Biology from 1973 to 1976. Biography Hayaishi was born in Stockton, California, United States, in 1920. He completed his medical degree in 1942 from Osaka University. After serving as a medical officer in the Japanese Navy for 3 years, he joined the Institute of Microbial Diseases, Osaka University and was awarded his Ph.D. in 1949. After working with Arthur Kornberg at the National Institute of Arthritis and Metabolic Diseases, National Institutes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Institute Of Medical Science (Japan)
The Institute of Medical Science (Tokyo-daigaku Ikagaku Kenkyujyo 東京大学医科学研究所) is an ancillary establishment of Tokyo University. It succeeded established in 1892 and is the foremost institute for medical and bioscience research in Japan. A research hospital is attached to the institute. The former Institute of Public Health was located on the site. History *1892: Dainihon Shiritu Eiseikai Fuzoku Densenbyo Kenkyujyo (Empire of Japan Private Sanitation Meeting Attachment Institute of Infectious Diseases) was established. *1899: It became the National Institute of Infectious Diseases under the jurisdiction of the Ministry of the Interior. *1914: The institute entered under the management of the Ministry of Education). *1916: It becomes an ancillary establishment of Tokyo Imperial University. *1967: Densenbyo Kenkyujyo (Institute of Infectious Diseases) was reorganized, then, Ikagaku Kenkyu-jyo (Institute of Medical Science) was established. Organization ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
