Sharpless Dihydroxylation Scheme
Sharpless is a surname. Notable people with the surname include: * Bevan Sharpless, solar system astronomer *Karl Barry Sharpless, American chemist and Nobel prize winner *Josh Sharpless, baseball player * Christopher Sharpless, 1988 Winter Olympics bobsledder * Mattie R. Sharpless (born 1942), American diplomat *Stewart Sharpless, galactic astronomer ** Sharpless catalog, a 20th-century astronomical catalog with 313 items *Isaac Sharpless, educator *Norman Sharpless, American oncologist and director of the National Cancer Institute *Disappearance of Toni Sharpless, an American nurse who disappeared in 2009 Fictional characters *A character in Madama Butterfly See also *Sharpless asymmetric dihydroxylation, a chemical reaction *Sharpless epoxidation The Sharpless epoxidation reaction is an enantioselective chemical reaction to prepare 2,3-epoxyalcohols from primary and secondary allylic alcohols. The oxidizing agent is ''tert''-butyl hydroperoxide. The method relies on a cata ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bevan Sharpless
Bevan Percival Sharpless (August 2, 1904 – October 28, 1950) was an American astronomer, best known for his 1944 discovery that the orbit of Phobos was decaying. Early life Sharpless was born to Ethel Mae Bevan and Albert Wayne Sharpless on August 2, 1904, in Chester Heights, Pennsylvania, the only child of the marriage. He attended Swarthmore High School then Swarthmore College, graduating in 1926 with an A.B. degree in mathematics. In 1923, he traveled with a group from the college to Yerbanis, Mexico to witness an eclipse of September 10, 1923, and again to New Haven, Connecticut, to observe the solar eclipse of January 24, 1925. He married Ethel May Gamble (1904-2002) on September 10, 1927, in Glenolden, Pennsylvania. Early career For two years after graduation, Sharpless worked as an actuary. He received a temporary appointment with the United States Naval Observatory on August 16, 1928; this became a permanent appointment as a junior astronomer on January 16, 1929. At ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Karl Barry Sharpless
Karl Barry Sharpless (born April 28, 1941) is an American chemist and a two-time Nobel laureate in Chemistry known for his work on stereoselective reactions and click chemistry. Sharpless was awarded half of the 2001 Nobel Prize in Chemistry "for his work on chirally catalysed oxidation reactions", and one third of the 2022 prize, jointly with Carolyn R. Bertozzi and Morten P. Meldal, "for the development of click chemistry and bioorthogonal chemistry". Sharpless is the fifth person (in addition to two organizations), to have twice been awarded a Nobel prize, along with Marie Curie, John Bardeen, Linus Pauling and Frederick Sanger, and the third to have been awarded two prizes in the same discipline (after Bardeen and Sanger). Early life and education Sharpless was born April 28, 1941, in Philadelphia, Pennsylvania. His childhood was filled with summers at his family cottage on the Manasquan River in New Jersey. This is where Sharpless developed a love for fishing that he wo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Josh Sharpless
Joshua David Sharpless (born January 26, 1981) is a former Major League Baseball right-handed relief pitcher. Biography Sharpless grew up in the greater Pittsburgh area, attending Freedom Area Senior High School in Freedom, Pennsylvania. Drafted in the 24th round of the 2003 Major League Baseball Draft out of Allegheny College, he progressed through the Pirates minor league system in three years. He reached the majors on August 1, , when trade-deadline moves left openings in the major league roster. He made his first appearance on August 2, 2006. Sharpless continued to live in the Pittsburgh area year-round while playing for the Pirates. After being released by the Pirates on March 31, , Sharpless signed a minor league contract with the San Francisco Giants on April 10, 2008. After becoming a free agent following the 2008 season, Sharpless signed with the York Revolution The York Revolution is an American professional minor-league baseball team based in York, Pennsylvania ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Christopher Sharpless
Christopher Sharpless (born August 23, 1945) is a bobsledder who represented the United States Virgin Islands The United States Virgin Islands,. Also called the ''American Virgin Islands'' and the ''U.S. Virgin Islands''. officially the Virgin Islands of the United States, are a group of Caribbean islands and an unincorporated and organized territory .... He competed in the two man event at the 1988 Winter Olympics. References External links * 1945 births Living people United States Virgin Islands male bobsledders Olympic bobsledders of the United States Virgin Islands Bobsledders at the 1988 Winter Olympics People from Bryan, Texas {{USVirginIslands-bobsleigh-bio-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mattie R
{{disambiguation ...
Mattie may refer to: * Mattie (name), a list of people and fictional characters with the given name or nickname * Mattie, Piedmont, Italy, a municipality * Mattie, West Virginia, United States, a ghost town * ''Grace Bailey'' (schooner), known as ''Mattie'' for many years See also * Matty (other) * Matti (other) Matti may refer to: * Matti (given name), people with the given name * Matti (surname), people with the surname * Matti, Karnataka, a village in India * '' Matti: Hell Is for Heroes'', a 2006 film about Matti Nykänen See also * Masa (disambigu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Stewart Sharpless
Stewart Sharpless (March 29, 1926 – January 19, 2013) was an American astronomer who carried out fundamental work on the structure of the Milky Way galaxy. As a graduate student at Yerkes Observatory he worked under William Morgan with fellow graduate student Don Osterbrock. He helped Harold Johnson and Morgan with calculations used to help define the UBV photometric system. In 1952, Sharpless and Osterbrock published their observations that demonstrated the spiral structure of the Milky Way by estimating the distances to H II regions and young hot stars. For a while Sharpless was at Mount Wilson Observatory where he worked on galaxy photography with Walter Baade and Edwin Hubble. In 1953 Sharpless joined the staff of the United States Naval Observatory Flagstaff Station. Here he surveyed and cataloged H II regions of the Milky Way Galaxy using the images from the Palomar Sky Survey. From this work Sharpless published his catalog of H II regions in two editions, the first ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sharpless Catalog
The Sharpless catalog is a list of 313 H II regions (emission nebulae) intended to be comprehensive north of declination −27°. (It does include some nebulae south of that declination as well.) The first edition was published in 1953 with 142 objects (Sh1), and the second and final version was published by US astronomer Stewart Sharpless in 1959 with 312 objects. Sharpless also includes some planetary nebulae and supernova remnants, in addition to H II regions. In 1953 Stewart Sharpless joined the staff of the United States Naval Observatory Flagstaff Station, where he surveyed and cataloged H II regions of the Milky Way using the images from the Palomar Sky Survey. From this work Sharpless published his catalog of H II regions in two editions: the first in 1953, with 142 nebula; and the second and final edition in 1959, with 312 nebulae.Stewart SharplessA Catalogue of H II Regions ''Astrophysical Journal'' Supplement, vol. 4, p.257, 1959 Sharpless coordinates ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Isaac Sharpless
Isaac Sharpless, Sc.D., LL.D., L.H.D. (1848–1920) was an American educator, born in Chester County, Pennsylvania. He graduated from Harvard in 1873 and received the honorary degree of Doctor of Divinity from there in 1915. He was employed at Haverford College for many years, becoming professor in 1879, dean in 1884, and president in 1887. In 1884, he was elected as a member of the American Philosophical Society. His birthplace, the Sharpless Homestead, is listed on the National Register of Historic Places The National Register of Historic Places (NRHP) is the United States federal government's official list of districts, sites, buildings, structures and objects deemed worthy of preservation for their historical significance or "great artistic v .... Books * ''Astronomy for Schools and General Readers'' (1882; fifth edition, revised, 1912) * ''English Education in the Elementary and Secondary Schools'', in the "International Education Series" (1892) * ''A Quaker Exp ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Norman Sharpless
Norman Edward "Ned" Sharpless (born September 20, 1966) is the previous Director of the National Cancer Institute (NCI). Before that, Sharpless was Professor of Medicine and Genetics Chair, Director of University of North Carolina UNC Lineberger Comprehensive Cancer Center, Molecular Therapeutics, Wellcome Distinguished Professorship in Cancer Research. Sharpless was named to head the NCI on June 10, 2017, and took office on October 17, 2017. Sharpless also served as Acting Commissioner of the Food and Drugs from April 5, 2019 until November 1, 2019, after which he returned to the NCI. He stepped down from the post at the end of April 2022. Education Sharpless studied mathematics at the University of North Carolina at Chapel Hill, where he was a John Motley Morehead Scholar. He earned his medical degree with honors and distinction at the University of North Carolina School of Medicine. He completed his internship and residency at Massachusetts General Hospital in Boston, and a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Disappearance Of Toni Sharpless
In the predawn hours of August 23, 2009, Toni Sharpless (born December 27, 1979)Missing person flyer reproduced at and her friend Crystal Johns left a party at the home of Philadelphia 76er Willie Green in Penn Valley, Pennsylvania, United States. Not long after leaving, Johns suggested to Sharpless, whose erratic and combative behavior had led Green to ask that they leave, that she was not sober enough to drive; in response, Sharpless pulled over and told Johns to get out, which she did. Sharpless has not been seen since then. An early theory, that she might have accidentally driven her car into the nearby Schuylkill River, was discarded when searches of the river were fruitless. An apparent break in the case came two weeks later when an automatic license plate reader recorded her 2002 Pontiac Grand Prix's plates among parked vehicles in Camden, New Jersey, across the Delaware River from Philadelphia. There had been other reported sightings of Sharpless in Camden, but police t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Madama Butterfly
''Madama Butterfly'' (; ''Madame Butterfly'') is an opera in three acts (originally two) by Giacomo Puccini, with an Italian libretto by Luigi Illica and Giuseppe Giacosa. It is based on the short story "Madame Butterfly" (1898) by John Luther Long, which in turn was based on stories told to Long by his sister Jennie Correll and on the semi-autobiographical 1887 French novel '' Madame Chrysanthème'' by Pierre Loti.Chadwick Jenna"The Original Story: John Luther Long and David Belasco" on columbia.edu Long's version was dramatized by David Belasco as the one-act play '' Madame Butterfly: A Tragedy of Japan'', which, after premiering in New York in 1900, moved to London, where Puccini saw it in the summer of that year. The original version of the opera, in two acts, had its premiere on 17 February 1904 at La Scala in Milan. It was poorly received, despite having such notable singers as soprano Rosina Storchio, tenor Giovanni Zenatello and baritone Giuseppe De Luca in lead roles ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sharpless Asymmetric Dihydroxylation
Sharpless asymmetric dihydroxylation (also called the Sharpless bishydroxylation) is the chemical reaction of an alkene with osmium tetroxide in the presence of a chiral quinine ligand to form a vicinal diol. The reaction has been applied to alkenes of virtually every substitution, often high enantioselectivities are realized, with the chiral outcome controlled by the choice of dihydroquinidine (DHQD) vs dihydroquinine (DHQ) as the ligand. Asymmetric dihydroxylation reactions are also highly site selective, providing products derived from reaction of the most electron-rich double bond in the substrate. It is common practice to perform this reaction using a catalytic amount of osmium tetroxide, which after reaction is regenerated with reoxidants such as potassium ferricyanide or ''N''-methylmorpholine ''N''-oxide. This dramatically reduces the amount of the highly toxic and very expensive osmium tetroxide needed. These four reagents are commercially available premixed (" AD- ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |