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SenesTech, Inc.
SenesTech, Inc. () is an agricultural biotechnology life-sciences company, specializing in fertility management as a form of pest control. The company's primary product, ContraPest is designed to make brown and black rats infertile. SenesTech is headquartered in Phoenix, Arizona. History The company was founded by Dr. Loretta Mayer and several colleagues, who were researching menopause in rodents. The commercial applications of their research became apparent, and they incorporated SenesTech in 2004. In 2019, SenesTech began selling directly to the public. Products ContraPest ContraPest is a sugary liquid, designed to be attractive to, and to be consumed by rats in order to eliminate future potential offspring. However, it does not sterilize the rats, so a continuous supply is required. The company claims that in field tests, ContraPest use caused a reduction in rat populations of roughly 40% over a period of 12 weeks or longer. The product was approved for commercial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Publicly Held Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), in Fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Black Rat
The black rat (''Rattus rattus''), also known as the roof rat, ship rat, or house rat, is a common long-tailed rodent of the stereotypical rat genus ''Rattus'', in the subfamily Murinae. It likely originated in the Indian subcontinent, but is now found worldwide. The black rat is black to light brown in colour with a lighter underside. It is a generalist omnivore and a serious pest to farmers because it feeds on a wide range of agricultural crops. It is sometimes kept as a pet. In parts of India, it is considered sacred and respected in the Karni Mata Temple in Deshnoke. Taxonomy ''Mus rattus'' was the scientific name proposed by Carl Linnaeus in 1758 for the black rat. Three subspecies were once recognized, but today are considered invalid and are now known to be actually color morphs: *''Rattus rattus rattus'' – roof rat *''Rattus rattus alexandrinus'' – Alexandrine rat *''Rattus rattus frugivorus'' – fruit rat Characteristics A typical adult black rat is long, n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology Companies Of The United States
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triptolide
Triptolide is a diterpenoid epoxide which is produced by the thunder god vine, ''Tripterygium wilfordii''. It has ''in vitro'' and ''in vivo'' activities against mouse models of polycystic kidney disease and pancreatic cancer, but its physical properties and severe toxicity limit its therapeutic potential. Consequently, a synthetic water-soluble prodrug, minnelide, is being studied clinically instead. Triptolide is a component of ContraPest, a contraceptive pest control liquid used to reduce rat populations in the United States. Mechanism of action Several putative target proteins of triptolide have been reported, including polycystin-2, ADAM10, DCTPP1, TAB1, and XPB. Multiple triptolide-resistant mutations exist in XPB (ERCC3) and its partner protein GTF2H4.Y. Smurnyy, M. Cai, H. Wu, E. McWhinnie, J. A. Tallarico, Y.Yang, Y. Feng, DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells. ''Nat. Chem. Biol''. 2014, 10, 623 – 625 However, no trip ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovarian Follicle
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence stages of the menstrual cycle. At the time of puberty, women have approximately 200,000 to 300,000 follicles, each with the potential to release an egg cell (ovum) at ovulation for fertilization. These eggs are developed once every menstrual cycle with around 450–500 being ovulated during a woman's reproductive lifetime. Structure Ovarian follicles are the basic units of female reproductive biology. Each of them contains a single oocyte (immature ovum or egg cell). These structures are periodically initiated to grow and develop, culminating in ovulation of usually a single competent oocyte in humans. They also consist of granulosa cells and theca of follicle. Oocyte Once a month, one of the ovaries releases a mature egg (ovum), known as an oocyte. The nucleus of such an oocyte is called a '' germinal vesicle (see picture).'' Cumulus oophorus Cumulu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oocyte
An oocyte (, ), oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis, forming oogonia. During oogenesis, the oogonia become primary oocytes. An oocyte is a form of genetic material that can be collected for cryoconservation. Formation The formation of an oocyte is called oocytogenesis, which is a part of oogenesis. Oogenesis results in the formation of both primary oocytes during fetal period, and of secondary oocytes after it as part of ovulation. Characteristics Cytoplasm Oocytes are rich in cytoplasm, which contains yolk granules to nourish the cell early in development. Nucleus During the primary oocyte stage of oogenesis, the nucleus is called a germinal vesicle. The only normal human type of secondary oocyte has t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
4-vinylcyclohexene Diepoxide
4-Vinylcyclohexene dioxide (VCD) is an organic compound that contains two epoxide functional groups. It is industrially used as a crosslinking agent for the production of epoxy resins. It is a colourless liquid. It is an intermediate for synthesis of organic compounds. Preparation and properties 4-Vinylcyclohexene dioxide is prepared by epoxidation of 4-vinylcyclohexene with peroxybenzoic acid. Its viscosity is 15 mPa·s. Safety 4-Vinylcyclohexene dioxide, like other volatile epoxides, is classified as an alkylating agent. VCD has toxic effects on fertility. It is a killer of oocytes, eggs in a female's ovaries, in immature ovarian follicles in mice and rats Rats are various medium-sized, long-tailed rodents. Species of rats are found throughout the order Rodentia, but stereotypical rats are found in the genus ''Rattus''. Other rat genera include ''Neotoma'' (pack rats), ''Bandicota'' (bandicoot .... In pest control, it has been used as an ovotoxic agent for reducing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sterilization (medicine)
Sterilization ( also spelled sterilisation) is any of a number of medical methods of birth control that intentionally leaves a person unable to reproduce. Sterilization methods include both surgical and non-surgical, and exist for both males and females. Sterilization procedures are intended to be permanent; reversal is generally difficult or impossible. There are multiple ways of having sterilization done, but the two that are used most frequently are tubal ligation for women and vasectomy for men. There are many different ways tubal sterilization can be accomplished. It is extremely effective and in the United States surgical complications are low. With that being said, tubal sterilization is still a method that involves surgery, so there is still a danger. Women that chose a tubal sterilization may have a higher risk of serious side effects, more than a man has with a vasectomy. Pregnancies after a tubal sterilization can still occur, even many years after the procedure. It is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
VCD And Triptolide
Video CD (abbreviated as VCD, and also known as Compact Disc Digital Video) is a home video format and the first format for distributing films on standard optical discs. The format was widely adopted in Southeast Asia, Central Asia and the Middle East, superseding the VHS and Betamax systems in the regions until DVD-Video finally became affordable in the first decade of the 21st century. The format is a standard digital data format for storing video on a compact disc. VCDs are playable in dedicated VCD players and widely playable in most DVD players, personal computers and some video game consoles. However, they are less playable in most Blu-ray Disc players, vehicle audio with DVD/Blu-ray support and video game consoles such as the Sony PlayStation and Xbox due to lack of backward compatibility for the older MPEG-1 format, inability to read MPEG-1 in .dat files alongside MPEG-1 in standard MPEG-1, AVI, and Matroska files, or inability to read CD-ROM XA discs. Some Laserdisc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CP Res-57
CP, cp. or its variants may refer to: Arts, entertainment, and media * Cariyapitaka (Cp), a canonical Buddhist story collection * The Canadian Press, a Canadian news agency * Child pornography * '' The Christian Post'', an American newspaper * Competitive programming * Club Penguin, a now defunct online multiplayer game * Creepypasta, a form of internet horror story * Cyberpunk, a subgenre of science fiction Enterprises Transportation companies * Canadian Airlines (1987–2001) (IATA airline code CP) * Canadian Pacific Railway, reporting mark CP * Central Pacific Railroad, a network of lines between California and Utah, US * , a French public railway company * , a Portuguese state-owned train company * CP Air or Canadian Pacific Air Lines (1942–1987), a Canadian airline * CP Ships, a Canadian shipping company, part of TUI Group * Cathay Pacific, a Hong Kong-based major airline Other enterprises * C.P. Company, an Italian apparel brand * Cedar Point, an amusement park in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brown Rat
The brown rat (''Rattus norvegicus''), also known as the common rat, street rat, sewer rat, wharf rat, Hanover rat, Norway rat, Norwegian rat and Parisian rat, is a widespread species of common rat. One of the largest muroids, it is a brown or grey rodent with a head and body length of up to long, and a tail slightly shorter than that. It weighs between . Thought to have originated in northern China and neighbouring areas, this rodent has now spread to all continents except Antarctica, and is the dominant rat in Europe and much of North America. With rare exceptions, the brown rat lives wherever humans live, particularly in urban areas. Selective breeding of the brown rat has produced the fancy rat (rats kept as pets), as well as the laboratory rat (rats used as model organisms in biological research). Both fancy rats and laboratory rats are of the domesticated subspecies ''Rattus norvegicus domestica''. Studies of wild rats in New York City have shown that populations livi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russell Microcap Index
The Russell Microcap Index measures the performance of the microcap segment of the U.S. equity market. It makes up less than 3% of the U.S. equity market. It includes 1,000 of the smallest securities in the Russell 2000 Index based on a combination of their market cap and current index membership and it also includes up to the next 1,000 stocks. , the weighted average market capitalization for a company in the index was $535 million; the median market cap was $228 million. The market cap of the largest company in the index was $3.6 billion. The index, which was launched on June 1, 2005, is maintained by FTSE Russell, a subsidiary of the London Stock Exchange Group. Its ticker symbol is ^RUMIC. Records In February 2021, during the everything bubble, a record 14 members of the index exceeded the market capitalization of the smallest member of the S&P 500 Index. Investing The Russell Microcap Index is tracked by the iShares Micro-Cap ETF (). Top 10 holdings *Mercury Systems () * Cen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
