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Sedimentation Coefficient
In chemistry, the sedimentation coefficient () of a particle characterizes its sedimentation (tendency to settle out of suspension) during centrifugation. It is defined as the ratio of a particle's sedimentation velocity to the applied acceleration causing the sedimentation. s = \frac The sedimentation speed is also the terminal velocity. It is constant because the force applied to a particle by gravity or by a centrifuge (typically in multiples of tens of thousands of gravities in an ultracentrifuge) is balanced by the viscous resistance (or "drag") of the fluid (normally water) through which the particle is moving. The applied acceleration can be either the gravitational acceleration , or more commonly the centrifugal acceleration . In the latter case, is the angular velocity of the rotor and is the distance of a particle to the rotor axis (radius). The viscous resistance for a spherical particle is given by Stokes' law: F_d = 6\pi\eta r_0 v where is the viscosi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during chemical reaction, reactions with other chemical substance, substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both Basic research, basic and Applied science, applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth (botany), the formation of igneous rocks (geology), how atmospheric ozone is formed and how environmental pollutants are degraded (ecology), the prop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radius
In classical geometry, a radius (: radii or radiuses) of a circle or sphere is any of the line segments from its Centre (geometry), center to its perimeter, and in more modern usage, it is also their length. The radius of a regular polygon is the line segment or distance from its center to any of its Vertex (geometry), vertices. The name comes from the Latin ''radius'', meaning ray but also the spoke of a chariot wheel.Definition of Radius at dictionary.reference.com. Accessed on 2009-08-08. The typical abbreviation and mathematical symbol for radius is ''R'' or ''r''. By extension, the diameter ''D'' is defined as twice the radius:Definition of radius at mathwords.com. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Svedberg
In chemistry, a Svedberg unit or svedberg (symbol S, sometimes Sv) is a non- SI metric unit for sedimentation coefficients. The Svedberg unit offers a measure of a particle's size indirectly based on its sedimentation rate under acceleration (i.e. how fast a particle of given size and shape settles out of suspension). The svedberg is a measure of time, defined as exactly 10−13 seconds (100 fs). For biological macromolecules like ribosomes, the sedimentation rate is typically measured as the rate of travel in a centrifuge tube subjected to high g-force. The svedberg (S) is distinct from the SI unit sievert or the non-SI unit sverdrup, which also use the symbol Sv, and to the SI unit Siemens which uses the symbol S too. Naming The unit is named after the Swedish chemist Theodor Svedberg (1884–1971), winner of the 1926 Nobel Prize in chemistry for his work on disperse systems, colloids and his invention of the ultracentrifuge. Factors The Svedberg coef ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clearing Factor
In centrifugation the clearing factor or k factor represents the relative pelleting efficiency of a given centrifuge rotor at maximum rotation speed. It can be used to estimate the time t (in hours) required for sedimentation of a fraction with a known sedimentation coefficient s (in svedbergs): : t = \frac The value of the clearing factor depends on the maximum angular velocity \omega of a centrifuge (in rad/s) and the minimum and maximum radius In classical geometry, a radius (: radii or radiuses) of a circle or sphere is any of the line segments from its Centre (geometry), center to its perimeter, and in more modern usage, it is also their length. The radius of a regular polygon is th ... r of the rotor: : k = \frac \times \frac As the rotational speed of a centrifuge is usually specified in RPM, the following formula is often used for convenience: : k = \frac Centrifuge manufacturers usually specify the minimum, maximum and average radius of a rotor, as well as the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nils Gralén
Nils is a Scandinavian given name, a chiefly Norwegian, Danish, Swedish and Latvian variant of Niels, cognate to Nicholas. People and animals with the given name * Nils Elias Anckers (1858–1921), Swedish naval officer * Nils Beckman (1902–1972), Swedish jurist and civil servant * Nils Bergström (born 1985), Swedish ice hockey player * Nils Björk (1898–1989), Swedish Army lieutenant general * Nils Dacke (died 1543), Swedish rebel * Nils-Joel Englund (1907–1995), Swedish cross-country skier *Nils Ericson (1802–1870), Swedish inventor and engineer * Nils Frahm (born 1982), German pianist and producer * Nils Frykdahl, American musician * Nils Grandelius, Swedish chess grandmaster * Nils Gründer (born 1997), German politician * Nils Hald (1897–1963), Norwegian actor * Nils Haßfurther (born 1999), German basketball player * Nils-Göran Holmqvist (born 1943), Swedish politician * Nils Kreicbergs (born 1996), Latvian handball player *Nils Liedholm (1922–2007), Swedish f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
30 S
The prokaryotic small ribosomal subunit, or 30 S subunit, is the smaller subunit of the 70S ribosome found in prokaryotes. It is a complex of the 16S ribosomal RNA (rRNA) and 19 proteins. This complex is implicated in the binding of transfer RNA to messenger RNA (mRNA). The small subunit is responsible for the binding and the reading of the mRNA during translation. The small subunit, both the rRNA and its proteins, complexes with the large 50S subunit to form the 70S prokaryotic ribosome in prokaryotic cells. This 70S ribosome is then used to translate mRNA into proteins. Function The 30S subunit is an integral part of mRNA translation. It binds three prokaryotic initiation factors: IF-1, IF-2, and IF-3. A portion of the 30S subunit (the 16S rRNA) guides the initiating start codon (5′)-AUG-(3′) of mRNA into position by recognizing the Shine-Dalgarno sequence, a complementary binding site about 8 base pairs upstream from the start codon. This ensures the ribosome sta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
50 S
50 S is the larger subunit of the 70S ribosome of prokaryotes, i.e. bacteria and archaea. It is the site of inhibition for antibiotics such as macrolides, chloramphenicol, clindamycin, and the pleuromutilins. It includes the 5S ribosomal RNA and 23S ribosomal RNA. Despite having the same sedimentation rate, bacterial and archaeal ribosomes can be quite different. Structure 50S, roughly equivalent to the 60S ribosomal subunit in eukaryotic cells, is the larger subunit of the 70S ribosome of prokaryotes. The 50S subunit is primarily composed of proteins but also contains single-stranded RNA known as ribosomal RNA (rRNA). rRNA forms secondary and tertiary structures to maintain the structure and carry out the catalytic functions of the ribosome. X-ray crystallography has yielded electron density maps allowing the structure of the 50S in '' Haloarcula marismortui'' (archaeon) to be determined to 2.4 Å resolutionand of the 50S in the '' Deinococcus radiodurans'' (bacter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, Hot spring, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the nitrogen fixation, fixation of nitrogen from the Earth's atmosphere, atmosphere. The nutrient cycle includes the decomposition of cadaver, dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, suc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosome
Ribosomes () are molecular machine, macromolecular machines, found within all cell (biology), cells, that perform Translation (biology), biological protein synthesis (messenger RNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA molecules to form polypeptide chains. Ribosomes consist of two major components: the small and large ribosomal subunits. Each subunit consists of one or more ribosomal RNA molecules and many ribosomal proteins (). The ribosomes and associated molecules are also known as the ''translational apparatus''. Overview The sequence of DNA that encodes the sequence of the amino acids in a protein is transcribed into a messenger RNA (mRNA) chain. Ribosomes bind to the messenger RNA molecules and use the RNA's sequence of nucleotides to determine the sequence of amino acids needed to generate a protein. Amino acids are selected and carried to the ribosome by transfer RNA (tRNA) molecules, which enter the riboso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Second
The second (symbol: s) is a unit of time derived from the division of the day first into 24 hours, then to 60 minutes, and finally to 60 seconds each (24 × 60 × 60 = 86400). The current and formal definition in the International System of Units (SI) is more precise: The second ..is defined by taking the fixed numerical value of the caesium frequency, Δ''ν''Cs, the unperturbed ground-state hyperfine transition frequency of the caesium 133 atom, to be when expressed in the unit Hz, which is equal to s−1. This current definition was adopted in 1967 when it became feasible to define the second based on fundamental properties of nature with caesium clocks. As the speed of Earth's rotation varies and is slowing ever so slightly, a leap second is added at irregular intervals to civil time to keep clocks in sync with Earth's rotation. The definition that is based on of a rotation of the earth is still used by the Universal Time 1 (UT1) system. Etymology "Minute" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Svedberg
In chemistry, a Svedberg unit or svedberg (symbol S, sometimes Sv) is a non- SI metric unit for sedimentation coefficients. The Svedberg unit offers a measure of a particle's size indirectly based on its sedimentation rate under acceleration (i.e. how fast a particle of given size and shape settles out of suspension). The svedberg is a measure of time, defined as exactly 10−13 seconds (100 fs). For biological macromolecules like ribosomes, the sedimentation rate is typically measured as the rate of travel in a centrifuge tube subjected to high g-force. The svedberg (S) is distinct from the SI unit sievert or the non-SI unit sverdrup, which also use the symbol Sv, and to the SI unit Siemens which uses the symbol S too. Naming The unit is named after the Swedish chemist Theodor Svedberg (1884–1971), winner of the 1926 Nobel Prize in chemistry for his work on disperse systems, colloids and his invention of the ultracentrifuge. Factors The Svedberg coef ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Time
Time is the continuous progression of existence that occurs in an apparently irreversible process, irreversible succession from the past, through the present, and into the future. It is a component quantity of various measurements used to sequence events, to compare the duration of events (or the intervals between them), and to quantify rates of change of quantities in material reality or in the qualia, conscious experience. Time is often referred to as a fourth dimension, along with Three-dimensional space, three spatial dimensions. Time is one of the seven fundamental physical quantities in both the International System of Units (SI) and International System of Quantities. The SI base unit of time is the second, which is defined by measuring the electronic transition frequency of caesium atoms. General relativity is the primary framework for understanding how spacetime works. Through advances in both theoretical and experimental investigations of spacetime, it has been shown ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
