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Samuel Wilks
Sir Samuel Wilks, 1st Baronet, (2 June 1824 – 8 November 1911) was a British physician and biographer. Early life Samuel Wilks was born on 2 June 1824 in Camberwell, London, the second son of Joseph Barber Wilks, a cashier at the East India House. After attending Aldenham School and University College School he was apprenticed to Richard Prior, a doctor in Newington. Career In 1842 he entered Guy's Hospital to study medicine. After graduating MB in 1848 he was hired as a physician to the Surrey Infirmary (1853). In 1856 he returned to Guy's Hospital, first as assistant physician and curator of its museum (a post he held for nine years), then as physician and lecturer on medicine (1857). From 1866 to 1870 he was examiner in the practice of medicine at the University of London and from 1868 to 1875 examiner in medicine at the Royal College of Surgeons. Achievements Among his major discoveries, Wilks recognised ulcerative colitis in 1859, differentiating it from bacterial dyse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guy's Hospital
Guy's Hospital is an NHS hospital in the borough of Southwark in central London. It is part of Guy's and St Thomas' NHS Foundation Trust and one of the institutions that comprise the King's Health Partners, an academic health science centre. It is a large teaching hospital and is, with St Thomas' Hospital and King's College Hospital, the location of King's College London GKT School of Medical Education. The hospital's Tower Wing (originally known as Guy's Tower) was, when built in 1974, the tallest hospital building in the world, standing at with 34 floors. The tower was overtaken as the world's tallest healthcare-related building by The Belaire in New York City in 1988. As of June 2019, the Tower Wing, which remains one of the tallest buildings in London, is the world's fifth-tallest hospital building. History The hospital dates from 1721, when it was founded by philanthropist Thomas Guy, who had made a fortune as a printer of Bibles and greatly increased it by speculat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ileum
The ileum () is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms posterior intestine or distal intestine may be used instead of ileum. Its main function is to absorb vitamin B12, bile salts, and whatever products of digestion that were not absorbed by the jejunum. The ileum follows the duodenum and jejunum and is separated from the cecum by the ileocecal valve (ICV). In humans, the ileum is about 2–4 m long, and the pH is usually between 7 and 8 (neutral or slightly basic). ''Ileum ''is derived from the Greek word ''eilein'', meaning "to twist up tightly". Structure The ileum is the third and final part of the small intestine. It follows the jejunum and ends at the ileocecal junction, where the terminal ileum communicates with the cecum of the large intestine through the ileocecal valve. The ileum, along with the jejunum, is suspended ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Hodgkin
Thomas Hodgkin RMS (17 August 1798 – 5 April 1866) was a British physician, considered one of the most prominent pathologists of his time and a pioneer in preventive medicine. He is now best known for the first account of Hodgkin's disease, a form of lymphoma and blood disease, in 1832. Hodgkin's work marked the beginning of times when a pathologist was actively involved in the clinical process. He was a contemporary of Thomas Addison and Richard Bright at Guy's Hospital in London. Early life Thomas Hodgkin was born to a Quaker family in Pentonville, St. James Parish, Middlesex, the son of John Hodgkin. He received private education with his brother John Hodgkin, and in 1816 took a position as private secretary to William Allen. His aim was to learn the trade of apothecary, one of the routes into medicine, and Allen, despite prominence in that business, did not make it possible. They parted, and Hodgkin went to an apothecary cousin, John Glaisyer, in Brighton instead. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bright's Disease
Bright's disease is a historical classification of kidney diseases that are described in modern medicine as acute or chronic nephritis. It was characterized by swelling and the presence of albumin in the urine, and was frequently accompanied by high blood pressure and heart disease. Signs and symptoms The symptoms and signs of Bright's disease were first described in 1827 by the English physician Richard Bright, after whom the disease was named. In his ''Reports of Medical Cases'', he described 25 cases of dropsy ( edema) which he attributed to kidney disease. Symptoms and signs included: inflammation of serous membranes, hemorrhages, apoplexy, convulsions, blindness and coma. Many of these cases were found to have albumin in their urine (detected by the spoon and candle-heat coagulation), and showed striking morbid changes of the kidneys at autopsy. The triad of dropsy, albumin in the urine, and kidney disease came to be regarded as characteristic of Bright's disease. Sub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Bright (physician)
Richard Bright (28 September 1789 – 16 December 1858) was an English physician and early pioneer in the research of kidney disease. He is particularly known for his description of Bright's disease. Biography He was born in Bristol, Gloucestershire, the third son of Sarah and Richard Bright Sr., a wealthy merchant and banker. Bright Sr. shared his interest in science with his son, encouraging him to consider it as a career. In 1808, Bright Jr. joined the University of Edinburgh to study philosophy, economics and mathematics, but switched to medicine the following year. In 1810, he accompanied Sir George Mackenzie on a summer expedition to Iceland where he conducted naturalist studies. Bright then continued his medical studies at Guy's Hospital in London and in September 1813 returned to Edinburgh to be granted his medical doctorate. His thesis was ''De erysipelate contagioso'' (''On contagious erysipelas''). During the 1820s and 1830s Bright again worked at Guy's Hospital, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Addison's Disease
Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency. Symptoms generally come on slowly and insidiously and may include abdominal pain and gastrointestinal abnormalities, weakness, and weight loss. Darkening of the skin in certain areas may also occur. Under certain circumstances, an adrenal crisis may occur with low blood pressure, vomiting, lower back pain, and loss of consciousness. Mood changes may also occur. Rapid onset of symptoms indicates acute adrenal failure which is a serious and emergent condition. An adrenal crisis can be triggered by stress, such as from an injury, surgery, or infection. Addison's disease arises from problems with the adrenal gland such that not enough of the steroid hormone cortisol and possibly aldo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Addison
Thomas J Addison (April 179329 June 1860) was an English physician, chef, and scientist. He is traditionally regarded as one of the "great men" of Guy's Hospital in London. Among other pathologies, he discovered Addison's disease (a degenerative disease of the adrenal glands) and Addisonian anemia (pernicious anemia), a hematological disorder later found to be caused by failure to absorb vitamin B12. Early years Thomas Addison was born in April 1793, but his exact birthdate is not known. He was born in Longbenton, near Newcastle upon Tyne, the son of Sarah and Joseph Addison, a grocer and flour dealer in Long Benton. He attended the local Thomas Rutter school and then went to the Royal Free Grammar School in Newcastle upon Tyne. He learned Latin so well that he made notes in Latin and spoke it fluently. Addison's father wanted him to become a lawyer, but he entered the University of Edinburgh Medical School in 1812 as a medical student. He became a member of the Royal Medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myasthenia Gravis
Myasthenia gravis (MG) is a long-term neuromuscular junction disease that leads to varying degrees of skeletal muscle weakness. The most commonly affected muscles are those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. Onset can be sudden. Those affected often have a large thymus or develop a thymoma. Myasthenia gravis is an autoimmune disease of the neuro-muscular junction which results from antibodies that block or destroy nicotinic acetylcholine receptors (AChR) at the junction between the nerve and muscle. This prevents nerve impulses from triggering muscle contractions. Most cases are due to immunoglobulin G1 (IgG1) and IgG3 antibodies that attack AChR in the postsynaptic membrane, causing complement-mediated damage and muscle weakness. Rarely, an inherited genetic defect in the neuromuscular junction results in a similar condition known as congenital myasthenia. Babies of mothers with myasthe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Korsakoff's Syndrome
Korsakoff syndrome (KS) is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation. This neurological disorder is caused by a deficiency of thiamine (vitamin B1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. Korsakoff syndrome is often accompanied by Wernicke encephalopathy; this combination is called Wernicke–Korsakoff syndrome. Korsakoff syndrome is named after Sergei Korsakoff, the Russian neuropsychiatrist who described it during the late 19th century. Signs and symptoms There are seven major symptoms of Korsakoff syndrome, an amnestic- confabulatory syndrome: # anterograde amnesia, memory loss for events after the onset of the syndrome # retrograde amnesia, memory loss extends back for some time before the onset of the syndrome # amnesia of fixation, also known as fixation amnesia (loss of immediate memory, a person being unable to remember eve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paraplegia
Paraplegia, or paraparesis, is an impairment in motor or sensory function of the lower extremities. The word comes from Ionic Greek () "half-stricken". It is usually caused by spinal cord injury or a congenital condition that affects the neural (brain) elements of the spinal canal. The area of the spinal canal that is affected in paraplegia is either the thoracic, lumbar, or sacral regions. If four limbs are affected by paralysis, tetraplegia or quadriplegia is the correct term. If only one limb is affected, the correct term is monoplegia. Spastic paraplegia is a form of paraplegia defined by spasticity of the affected muscles, rather than flaccid paralysis. The American Spinal Injury Association classifies spinal cord injury severity in the following manner. ASIA A is the complete loss of sensory function and motor skills below the injury. ASIA B is having some sensory function below the injury, but no motor function. In ASIA C, there is some motor function below the level of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tracheobronchopathia Osteochondroplastica
Tracheobronchopathia osteochondroplastica (TO) is a rare benign disease of unknown cause, in which multiple cartilaginous or bony submucosal nodules project into the trachea and proximal bronchi. The nodules usually spare the posterior wall of the airway because they are of cartilaginous origin, while the posterior wall of the airway is membranous (does not contain cartilage). This is as opposed to tracheobronchial amyloidosis, which does not spare the posterior wall. It usually occurs in men around their fifth decade of life, as opposed to tracheobronchial papillomatosis due to HPV infection, which usually occurs in younger patients. TO can cause airway obstruction, bleeding and chronic cough. Treatment involves the use of bronchodilators, and physical dilatation by bronchoscopy. The patients are also more prone to post-obstructive pneumonia and chronic lung infection in severe cases. Diagnosis Differential diagnosis The differential of TO includes amyloidosis, which is typical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dermatologist
Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical doctor who manages diseases related to skin, hair, nails, and some cosmetic problems. Etymology Attested in English in 1819, the word "dermatology" derives from the Greek δέρματος (''dermatos''), genitive of δέρμα (''derma''), "skin" (itself from δέρω ''dero'', "to flay") and -λογία '' -logia''. Neo-Latin ''dermatologia'' was coined in 1630, an anatomical term with various French and German uses attested from the 1730s. History In 1708, the first great school of dermatology became a reality at the famous Hôpital Saint-Louis in Paris, and the first textbooks (Willan's, 1798–1808) and atlases ( Alibert's, 1806–1816) appeared in print around the same time.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
