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SAAM II
SAAM II, short for "Simulation Analysis and Modeling" version 2.0, is a renowned computer program designed for scientific research in the field of bioscience. It is a descriptive and exploratory tool in drug development, tracers, metabolic disorders, and pharmacokinetics/pharmacodynamics research. It is grounded in the principles of multi-compartment model theory, which is a widely-used approach for modeling complex biological systems. SAAM II facilitates the construction and simulation of models, providing researchers with a friendly user interface allowing the quick run and multi-fitting of simple and complex (linear and nonlinear) structures and data. SAAM II is used by many Pharma and Pharmacy Schools as a drug development, research, and educational tool. Features The compartmental module SAAM II offers a user-friendly interface that eliminates the need for coding. Within the compartmental module, users can construct models effortlessly by drag-and-dropping various model c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multi-compartment Model
A multi-compartment model is a type of mathematical model used for describing the way materials or energies are transmitted among the ''compartments'' of a system. Sometimes, the physical system that we try to model in equations is too complex, so it is much easier to discretize the problem and reduce the number of parameters. Each compartment is assumed to be a homogeneous entity within which the entities being modeled are equivalent. A multi-compartment model is classified as a lumped parameters model. Similar to more general mathematical models, multi-compartment models can treat variables as continuous, such as a differential equation, or as discrete, such as a Markov chain. Depending on the system being modeled, they can be treated as stochastic or deterministic. Multi-compartment models are used in many fields including pharmacokinetics, epidemiology, biomedicine, systems theory, complexity theory, engineering, physics, information science and social science. The circuits sys ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Simone Perazzolo
Simone may refer to: * Simone (given name), a feminine (or Italian masculine) given name of Hebrew origin * Simone (surname), an Italian surname Simone may also refer to: * Simone (1918 film), ''Simone'' (1918 film), a French silent drama film * Simone (1926 film), ''Simone'' (1926 film), a French silent drama film * Simone (2002 film), ''Simone'' (2002 film), a 2002 science-fiction drama film * Simone (2013 film), ''Simone'' (2013 film), a 2013 Brazilian drama * Simone (actress) (born 1962), stage name of Lisa Celeste Stroud, daughter of Nina Simone * Nina Simone (1933–2003), stage name of Eunice Kathleen Waymon, singer, songwriter, musician, arranger, and civil rights activist * Simone Philip Kamel, Simone (born 1966), Egyptian singer and actress * Simone (character), a fictional character in the ABC Family show ''The Nine Lives of Chloe King'' * Simone Bittencourt de Oliveira (born 1949), Brazilian singer and performer, better known by her mononym Simone * Simone Egeriis (bor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sun Microsystems
Sun Microsystems, Inc. (Sun for short) was an American technology company that sold computers, computer components, software, and information technology services and created the Java programming language, the Solaris operating system, ZFS, the Network File System (NFS), and SPARC microprocessors. Sun contributed significantly to the evolution of several key computing technologies, among them Unix, RISC processors, thin client computing, and virtualized computing. Notable Sun acquisitions include Cray Business Systems Division, Storagetek, and ''Innotek GmbH'', creators of VirtualBox. Sun was founded on February 24, 1982. At its height, the Sun headquarters were in Santa Clara, California (part of Silicon Valley), on the former west campus of the Agnews Developmental Center. Sun products included computer servers and workstations built on its own RISC-based SPARC processor architecture, as well as on x86-based AMD Opteron and Intel Xeon processors. Sun also developed its own ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Washington
The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle approximately a decade after the city's founding. The university has a 703 acre main campus located in the city's University District, as well as campuses in Tacoma and Bothell. Overall, UW encompasses over 500 buildings and over 20 million gross square footage of space, including one of the largest library systems in the world with more than 26 university libraries, art centers, museums, laboratories, lecture halls, and stadiums. The university offers degrees through 140 departments, and functions on a quarter system. Washington is the flagship institution of the six public universities in Washington state. It is known for its medical, engineering, and scientific research. Washington is a member of the Association of American Universiti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacodynamics
Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology, being itself a topic of biology interested in the study of the interactions between both endogenous and exogenous chemical substances with living organisms. In particular, pharmacodynamics is the study of how a drug affects an organism, whereas pharmacokinetics is the study of how the organism affects the drug. Both together influence dosing, benefit, and adverse effects. Pharmacodynamics is sometimes abbreviated as PD and pharmacokinetics as PK, especially in combined reference (for example, when speaking of PK/PD models). Pharmacodynamics places particular emphasis on dose–response relationships, that is, the relationships between d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microsoft Windows
Windows is a group of several proprietary graphical operating system families developed and marketed by Microsoft. Each family caters to a certain sector of the computing industry. For example, Windows NT for consumers, Windows Server for servers, and Windows IoT for embedded systems. Defunct Windows families include Windows 9x, Windows Mobile, and Windows Phone. The first version of Windows was released on November 20, 1985, as a graphical operating system shell for MS-DOS in response to the growing interest in graphical user interfaces (GUIs). Windows is the most popular desktop operating system in the world, with 75% market share , according to StatCounter. However, Windows is not the most used operating system when including both mobile and desktop OSes, due to Android's massive growth. , the most recent version of Windows is Windows 11 for consumer PCs and tablets, Windows 11 Enterprise for corporations, and Windows Server 2022 for servers. Genealogy By marketing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacokinetics
Pharmacokinetics (from Ancient Greek ''pharmakon'' "drug" and ''kinetikos'' "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models. Overview Pharmacokinetics describes how the body affects a specific xenobiotic/chemical after administration through the mechanisms of absorption and distribution, as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metabolic Disorders
A metabolic disorder is a disorder that negatively alters the body's processing and distribution of macronutrients, such as Protein, proteins, Fat, fats, and Carbohydrate, carbohydrates. Metabolic disorders can happen when abnormal chemical reactions in the body alter the normal metabolic process. It can also be defined as inherited single gene anomaly, most of which are Dominance (genetics), autosomal recessive. Signs and symptoms Some of the symptoms that can occur with metabolic disorders are lethargy, weight loss, jaundice and seizures. The symptoms expressed would vary with the type of metabolic disorder. There are four categories of symptoms: acute symptoms, late-onset acute symptoms, progressive general symptoms and permanent symptoms. Causes Inherited metabolic disorders are one cause of metabolic disorders, and occur when a defective gene causes an enzyme deficiency. These diseases, of which there are many subtypes, are known as inborn errors of metabolism. Metabolic d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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