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Roche
F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth largest pharmaceutical company in the world by revenue, and the leading provider of cancer treatments globally. The company controls the American biotechnology company Genentech, which is a wholly owned affiliate, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States-based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020 were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, and Maja Oeri a further 5% apart), with Swiss pharma firm Novartis owning a fu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fritz Hoffmann-La Roche
Fritz Hoffmann-La Roche, later Fritz Hoffmann-von der Mühll (1868 1920), was a Swiss businessman who founded the pharmaceutical company F. Hoffmann-LaRoche & Co. Early life Hoffmann was born in Basel, Switzerland (french: link=no, Bâle) on the 24 October 1868 as the third child of Friedrich Hoffmann and Anna Elisabeth Merian. His godfathers were the parental grandfather Johan Heinrich Merian von der Mühll, his uncle, the Mayor of Basel Carl Felix Burckhardt von der Mühll and Anna Von der Mühll. His family were wealthy businesspeople from Basel's social elite (called the "Daig"), and they provided both employment experience and investment at the beginning of his business career. In the 1870s and 80s he absolved primary and high school in Basel and then absolved an apprenticeship at a bank in francophone part of Switzerland. When he returned to Basel in 1889 he entered a second internship at a pharmaceuical company.Wanner, Gustaf Adolf (1968). pp.25–27 Between 1891 and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genentech
Genentech, Inc., is an American biotechnology corporation headquartered in South San Francisco, California. It became an independent subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within Roche. Historically, the company is regarded as the world's first biotechnology company. As of July 2021, Genentech employed 13,539 people. History The company was founded in 1976 by venture capitalist Robert A. Swanson and biochemist Herbert Boyer. Boyer is considered to be a pioneer in the field of recombinant DNA technology. In 1973, Boyer and his colleague Stanley Norman Cohen demonstrated that restriction enzymes could be used as "scissors" to cut DNA fragments of interest from one source, to be ligated into a similarly cut plasmid vector. While Cohen returned to the laboratory in academia, Swanson contacted Boyer to found the company. Boyer worked with Arthur Riggs and Keiichi Itakura from the Beckman Research Institute, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
André Hoffmann (businessman)
André Hoffmann (born 31 May 1958) is a Swiss billionaire businessman, environmentalist and philanthropist. The great-grandson of Fritz Hoffmann-La Roche who founded the drug company Roche Holding in 1896, he currently is the vice-chairman of the company. As of November 2020, his estimated net worth is US$5.71 billion As a philanthropist, he has been an advocate for sustainability and environmental protection, serving as International Vice-president of the World Wide Fund for Nature (WWF) from 2007 to 2017. Early life Born on 31 May 1958 in Basel, Switzerland, André Hoffmann is the son of Daria Hoffmann-Razumovsky and Luc Hoffmann, a conservationist and philanthropist. He studied economics at the University of St. Gallen, and holds an MBA from INSEAD, completed in 1990. Career In 1991, André Hoffmann joined Nestlé UK. Three years later, he established a family office specialized in wealth management. In 1996, he became a member of the board of Roche holding, the worl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ventana Medical Systems
Ventana Medical Systems, Inc. was a medical device company that develops, manufactures, and markets instrument reagent systems that automate tissue and slide staining in anatomic pathology laboratories. These products assist in the diagnosis and treatment of cancer and infectious diseases. The company is now part of the Roche Diagnostics Division and has been renamed Roche Tissues Diagnostics. Company history Pathologist and University of Arizona professor Thomas Grogan, M.D., founded Ventana in 1985. The company launched its first instrument reagent system in 1991, and held an initial public offering (IPO) in 1996, trading under the symbol VMSI on the NASDAQ stock exchange. In 2007, Ventana acquired Spring BioScience Corp, a developer and supplier of monoclonal antibodies. That same year, Ventana rejected a hostile takeover bid from Roche Holding AG for $75 a share.Doherty, Dermot (January 22, 2008)Roche’s Higher Offer Wins Ventana After Seven Months (Update11) Bloomberg. R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roche Tower
Roche Tower (german: Roche-Turm) is a skyscraper in the Swiss city of Basel. At 178 metres, it is the second tallest building in the country. The building, also known as "Building 1" (german: Bau 1), was financed by pharmaceutical company Hoffmann-La Roche and designed by Herzog & de Meuron. It cost 550 million Swiss francs to build. The entire construction ensemble, including a planned 205-metre "Building 2" research facility, is expected to cost three billion francs in total. When finished on 18 September 2015, Roche Tower overtook Prime Tower in Zürich as Switzerland's tallest building, the latter having held the record for four years. Strict planning laws mean there are few skyscrapers in the country. For the construction of the building, measures against earthquakes were envisioned and it stands on 143 pillars of reinforced concrete. It is supposed to endure an earthquake of 6.9 on the Richter scale The Richter scale —also called the Richter magnitude scale, Richter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Foundation Medicine
Foundation Medicine, Inc. is an American company based in Cambridge, Massachusetts, which develops, manufactures, and sells genomic profiling assays based on next-generation sequencing technology for solid tumors, hematologic malignancies, and sarcomas. History Foundation Medicine was founded in Cambridge, Massachusetts. The company was conceived after Broad Institute researchers Levi Garraway and Matthew Meyerson published a 2007 paper detailing a method for large-panel testing of 238 DNA mutations. Foundation Medicine launched in 2010 with a $25 million Series A financing led by Third Rock Ventures. The company released its first commercial assay, or test, called FoundationOne in 2012. The company also began partnering with pharmaceutical companies to analyze patient samples. The first such program was piloted with Novartis in 2011, and by 2018, the company had more than 30 partnerships. Foundation Medicine launched its second test, a hematological biomarker assay call ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Redoxon
Redoxon was the brand name of the first artificially synthesized ascorbic acid (vitamin C). Redoxon was first marketed to the general public by Hoffman-La Roche in 1934, making it the first mass-manufactured synthetic vitamin in history. The brand is now owned by German pharmaceutical company Bayer and is sold in many countries. History The product was developed by a team headed by chemist Tadeusz Reichstein, who discovered a method of synthesizing 30-40 grams of vitamin C from 100 grams of glucose. This used an intermediate step of creating sorbose using a bacterial fermentation method discovered by a French researcher, Gabriel Bertrand. In this method, fruit flies were attracted to a mixture of wine, vinegar, yeast bouillon, and sorbitol, a substance easily chemically prepared from glucose. Flies that fed upon sorbitol as a major food substrate excreted bacteria that were able to synthesize sorbose from sorbitol. The bacteria species was isolated, cultured and used in a fermen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basel
, french: link=no, Bâlois(e), it, Basilese , neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS), Saint-Louis (FR-68), Weil am Rhein (DE-BW) , twintowns = Shanghai, Miami Beach , website = www.bs.ch Basel ( , ), also known as Basle ( ),french: Bâle ; it, Basilea ; rm, label= Sutsilvan, Basileia; other rm, Basilea . is a city in northwestern Switzerland on the river Rhine. Basel is Switzerland's third-most-populous city (after Zürich and Geneva) with about 175,000 inhabitants. The official language of Basel is (the Swiss variety of Standard) German, but the main spoken language is the local Basel German dialect. Basel is commonly considered to be the cultural capital of Switzerland and the city is famous for its many museums, including the Kunstmuseum, which is the first collection of art accessibl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-locations It is one of the largest pharmaceutical companies in the world. Novartis manufactures the drugs clozapine (Clozaril), diclofenac (Voltaren; sold to GlaxoSmithKline in 2015 deal), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec/Glivec), cyclosporine (Neoral/Sandimmune), letrozole (Femara), methylphenidate (Ritalin; production ceased 2020), terbinafine (Lamisil), deferasirox (Exjade), and others. In March 1996, the companies Ciba-Geigy and Sandoz merged to form Novartis; the pharmaceutical and agrochemical divisions of both companies formed Novartis as an independent entity. Other Ciba-Geigy and Sandoz businesses were sold, or, like Ciba Specialty Chemicals, spun off as independent companies. The Sandoz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chugai Pharmaceutical Co
is a drug manufacturer operating in Japan. It is a subsidiary controlled by Hoffmann-La Roche, which owns 62% of the company as of 30 June 2014. The company is headquartered in Tokyo. Osamu Nagayama is the current representative director and chairman. Tatsuro Kosaka is the current representative director, president and CEO. History Timeline This is a timeline of important events of Chugai Pharmaceutical. * 1925: Juzo Ueno founded Chugai Shinyaku Co. Ltd. and started importing and selling medicines * 1927: Start of the first own production * 1930: Salobrocanon, an analgesic (pain reliever) and antipyretic is launched * 1937: Calcium bromide production begins * 1943: Name changed to Chugai Pharmaceutical Co., Ltd. based in Tokyo * 1944: Acquisition of Matsunaga Pharmaceutical Ltd. and construction of a plant in Matsunaga * 1945: The headquarters, the factories in Ikebukuro, Sakai and Takada were destroyed in World War II, the headquarters were relocated to Takada, the factory ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christoph Franz
Christoph Franz (born 2 May 1960 in Frankfurt) is a German engineer and manager who served as chief executive officer of Lufthansa from 2011 until 2014. Early life and education Franz studied industrial engineering at the Technical University of Darmstadt and completed his studies with a Ph.D. in economic sciences at the same university. He also studied at the École centrale de Lyon and conducted post-doctorate research at the University of California, Berkeley. Career Franz joined Lufthansa in 1990. During that time, he was involved in Lufthansa's turnround following the Gulf War, when he served in the office of Jürgen Weber, the then chief executive. In 1994 Franz moved to German railway operator Deutsche Bahn. From 2004 until 2009 he was CEO of Swiss International Air Lines. From 1 January 2011 until 30 April 2014 he served as CEO of Deutsche Lufthansa AG as successor of Wolfgang Mayrhuber. During his time in office, he sought to fight back against the budget airlines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin C
Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits and vegetables, also sold as a dietary supplement and as a topical 'serum' ingredient to treat melasma (dark pigment spots) and wrinkles on the face. It is used to prevent and treat scurvy. Vitamin C is an essential nutrient involved in the repair of tissue, the formation of collagen, and the enzymatic production of certain neurotransmitters. It is required for the functioning of several enzymes and is important for immune system function. It also functions as an antioxidant. Most animals are able to synthesize their own vitamin C. However, apes (including humans) and monkeys (but not all primates), most bats, some rodents, and certain other animals must acquire it from dietary sources. There is some evidence that regular use of supplements may reduce the duration of the common cold, but it does not appear to prevent infection. It is unclear whether ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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