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Robert Tigerstedt
Robert Adolph Armand Tigerstedt (28 February 1853 – 12 February 1923) was a Finnish-born medical scientist and physiologist who, with his student Per Bergman, discovered renin at the Karolinska Institute, Stockholm in 1898. Renin is a component of the renin–angiotensin system which regulates blood pressure, salt and water homeostasis and is an important therapeutic target. Tigerstedt is also recognised as an educator, author and social campaigner. Biography Early life Tigerstedt was born in Helsinki on 28 February 1853. His parents were Karl Konstatin Tigerstedt and Evelina Theresia Tigerstedt (née Degerman). Karl Konstatin was a professor of history at the University of Helsinki. Adult life Tigerstedt matriculated from Åbo Gymnasium in Turku in 1869, and then studied physical and natural sciences at the University of Helsinki, where he was taught by the notable chemist Carl Axel Arrhenius. He graduated from the University of Helsinki with a Master of Arts degree in 1873 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helsinki
Helsinki ( or ; ; sv, Helsingfors, ) is the Capital city, capital, primate city, primate, and List of cities and towns in Finland, most populous city of Finland. Located on the shore of the Gulf of Finland, it is the seat of the region of Uusimaa in southern Finland, and has a population of . The Helsinki urban area, city's urban area has a population of , making it by far the List of urban areas in Finland by population, most populous urban area in Finland as well as the country's most important center for politics, education, finance, culture, and research; while Tampere in the Pirkanmaa region, located to the north from Helsinki, is the second largest urban area in Finland. Helsinki is located north of Tallinn, Estonia, east of Stockholm, Sweden, and west of Saint Petersburg, Russia. It has History of Helsinki, close historical ties with these three cities. Together with the cities of Espoo, Vantaa, and Kauniainen (and surrounding commuter towns, including the eastern ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prohibition
Prohibition is the act or practice of forbidding something by law; more particularly the term refers to the banning of the manufacture, storage (whether in barrels or in bottles), transportation, sale, possession, and consumption of alcoholic beverages. The word is also used to refer to a period of time during which such bans are enforced. History Some kind of limitation on the trade in alcohol can be seen in the Code of Hammurabi (c. 1772 BCE) specifically banning the selling of beer for money. It could only be bartered for barley: "If a beer seller do not receive barley as the price for beer, but if she receive money or make the beer a measure smaller than the barley measure received, they shall throw her into the water." In the early twentieth century, much of the impetus for the prohibition movement in the Nordic countries and North America came from moralistic convictions of pietistic Protestants. Prohibition movements in the West coincided with the advent of women's su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alfred Nobel
Alfred Bernhard Nobel ( , ; 21 October 1833 – 10 December 1896) was a Swedes, Swedish chemist, engineer, inventor, businessman, and Philanthropy, philanthropist. He is best known for having bequeathed his fortune to establish the Nobel Prize, though he also made several important contributions to science, holding 355 patents in his lifetime. Nobel's most famous invention was dynamite, a safer and easier means of harnessing the explosive power of nitroglycerin; it was patented in 1867. Nobel displayed an early aptitude for science and learning, particularly in chemistry and languages; he became fluent in six languages and filed his first patent at age 24. He embarked on many business ventures Nobel family, with his family, most notably owning Bofors, an iron and steel producer that he developed into a major manufacturer of cannons and other armaments. Nobel was later inspired to donate his fortune to the Nobel Prize institution, which would annually recognize those who ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Irvine Page
Irvine Heinly Page (January 7, 1901 – June 10, 1991) was an American physiologist who played an important part in the field of hypertension for almost 60 years while working at the Cleveland Clinic as the first Chair of Research.Frohlich ED, Dustan HP, Bumpus FM Irvine H. Page: 1901-1991. The Celebration of a Leader' Hypertension 1991;18:443–445. Early life and education Irvine Page was born on January 7, 1901, in Indianapolis, Indiana. He attended college at Cornell University, with an undergraduate degree in chemistry (1921) and an M.D. degree in 1926. Page completed his internship at Presbyterian and Bellevue Hospitals in New York City. Career After completing his internship, Page then performed research in physical chemistry at Woods Hole and then New York. In 1928 he joined the Kaiser Wilhelm Institute in Munich, Germany where he started a new department of neurochemistry. With the coming rise to power of Hitler, Page left Munich in 1931 to work with Donald Van Slyke a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vasoconstriction
Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles. The process is the opposite of vasodilation, the widening of blood vessels. The process is particularly important in controlling hemorrhage and reducing acute blood loss. When blood vessels constrict, the flow of blood is restricted or decreased, thus retaining body heat or increasing vascular resistance. This makes the skin turn paler because less blood reaches the surface, reducing the radiation of heat. On a larger level, vasoconstriction is one mechanism by which the body regulates and maintains mean arterial pressure. Medications causing vasoconstriction, also known as vasoconstrictors, are one type of medicine used to raise blood pressure. Generalized vasoconstriction usually results in an increase in systemic blood pressure, but it may also occur in specific tissues, causing a localized reduction in bl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vasoconstriction
Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles. The process is the opposite of vasodilation, the widening of blood vessels. The process is particularly important in controlling hemorrhage and reducing acute blood loss. When blood vessels constrict, the flow of blood is restricted or decreased, thus retaining body heat or increasing vascular resistance. This makes the skin turn paler because less blood reaches the surface, reducing the radiation of heat. On a larger level, vasoconstriction is one mechanism by which the body regulates and maintains mean arterial pressure. Medications causing vasoconstriction, also known as vasoconstrictors, are one type of medicine used to raise blood pressure. Generalized vasoconstriction usually results in an increase in systemic blood pressure, but it may also occur in specific tissues, causing a localized reduction in bl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renal Medulla
The renal medulla is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries. The interlobar arteries each in turn branch into arcuate arteries, which in turn branch to form interlobular arteries, and these finally reach the glomeruli. At the glomerulus the blood reaches a highly disfavourable pressure gradient and a large exchange surface area, which forces the serum portion of the blood out of the vessel and into the renal tubules. Flow continues through the renal tubules, including the proximal tubule, the Loop of Henle, through the distal tubule and finally leaves the kidney by means of the collecting duct, leading to the renal pelvis, the dilated portion of the ureter. The renal medulla (Latin: ''medulla renis'' 'marrow of the kidney') contains the structures of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renal Cortex
The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. In the adult, it forms a continuous smooth outer zone with a number of projections ( cortical columns) that extend down between the pyramids. It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts. The renal cortex is the part of the kidney where ultrafiltration occurs. Erythropoietin is produced in the renal cortex. Additional images File:Njuren.gif, Kidney File:Kidney-Cortex.JPG, Microscopic cross section of the renal cortex File:Kidney_cd10_ihc.jpg, CD10 immunohistochemical staining of normal kidney. CD10 stains the proximal convoluted tubules and glomeruli ''Glomerulus'' () is a common term used in anatomy to describe globular structures of entwined vessels, fibers, or neurons. ''Glomerulus'' is the diminutive of the Latin ''glomus'', me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kidney
The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid–base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles-Édouard Brown-Séquard
Charles-Édouard Brown-Séquard FRS (8 April 1817 – 2 April 1894) was a Mauritian physiologist and neurologist who, in 1850, became the first to describe what is now called Brown-Séquard syndrome. Early life Brown-Séquard was born at Port Louis, Mauritius, to an American father and a French mother. He attended the Royal College in Mauritius, and graduated in medicine at Paris in 1846. He then returned to Mauritius with the intention of practising there, but in 1852 he went to the United States. There he was appointed to the faculty of the Medical College of Virginia where he conducted experiments in the basement of the Egyptian Building. He was elected as a member of the American Philosophical Society in 1854. Later life He returned to Paris, and in 1859 he migrated to London, becoming physician to the National Hospital for the Paralysed and Epileptic. There he stayed for about five years, expounding his views on the pathology of the nervous system in numerous lectures wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Attack
A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to the coronary artery of the heart, causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck or jaw. Often it occurs in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat or feeling tired. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, cardiogenic shock or cardiac arrest. Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Finnish Civil War
The Finnish Civil War; . Other designations: Brethren War, Citizen War, Class War, Freedom War, Red Rebellion and Revolution, . According to 1,005 interviews done by the newspaper ''Aamulehti'', the most popular names were as follows: Civil War 29%, Citizen War 25%, Class War 13%, Freedom War 11%, Red Rebellion 5%, Revolution 1%, other name 2% and no answer 14%, was a civil war in Finland in 1918 fought for the leadership and control of the country between White Finland and the Finnish Socialist Workers' Republic (Red Finland) during the country's transition from a grand duchy of the Russian Empire to an independent state. The clashes took place in the context of the national, political, and social turmoil caused by World War I ( Eastern Front) in Europe. The war was fought between the "Reds", led by a section of the Social Democratic Party, and the "Whites", conducted by the conservative-based senate and the German Imperial Army. The paramilitary Red Guards, which were co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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