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Right-handed
In human biology, handedness is an individual's preferential use of one hand, known as the dominant hand, due to it being stronger, faster or more dextrous. The other hand, comparatively often the weaker, less dextrous or simply less subjectively preferred, is called the non-dominant hand. In a study from 1975 on 7688 children in US grades 1-6, Left handers comprised 9.6% of the sample, with 10.5% of male children and 8.7% of female children being left-handed. Handedness is often defined by one's writing hand, as it is fairly common for people to prefer to do some tasks with each hand. There are examples of true ambidexterity (equal preference of either hand), but it is rare—most people prefer using one hand for most purposes. Most of the current research suggests that left-handedness has an epigenetic marker—a combination of genetics, biology and the environment. Because the vast majority of the population is right-handed, many devices are designed for use by right-hand ...
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Ambidexterity
Ambidexterity is the ability to use both the right and left hand equally well. When referring to objects, the term indicates that the object is equally suitable for right-handed and left-handed people. When referring to humans, it indicates that a person has no marked preference for the use of the right or left hand. Only about one percent of people are naturally ambidextrous, which equates to about 70,000,000 people in the world. In modern times, it is common to find some people considered ambidextrous who were originally left-handed and who learned to be ambidextrous, either deliberately or as a result of training in schools or in jobs where right-handed habits are often emphasized or required. Since many everyday devices (such as can openers and scissors) are asymmetrical and designed for right-handed people, many left-handers learn to use them right-handedly due to the rarity or lack of left-handed models. Thus, left-handed people are more likely to develop motor skills in ...
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Ambidexterity
Ambidexterity is the ability to use both the right and left hand equally well. When referring to objects, the term indicates that the object is equally suitable for right-handed and left-handed people. When referring to humans, it indicates that a person has no marked preference for the use of the right or left hand. Only about one percent of people are naturally ambidextrous, which equates to about 70,000,000 people in the world. In modern times, it is common to find some people considered ambidextrous who were originally left-handed and who learned to be ambidextrous, either deliberately or as a result of training in schools or in jobs where right-handed habits are often emphasized or required. Since many everyday devices (such as can openers and scissors) are asymmetrical and designed for right-handed people, many left-handers learn to use them right-handedly due to the rarity or lack of left-handed models. Thus, left-handed people are more likely to develop motor skills in ...
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Cross-dominance
Cross-dominance, also known as mixed- handedness, hand confusion, or mixed dominance, is a motor skill manifestation in which a person favors one hand for some tasks and the other hand for others, or a hand and the contralateral leg. For example, a cross-dominant person might write with the right hand and do everything else with the left one, or manage and kick a ball preferentially with the left leg. It can also refer to mixed laterality, which refers to a person favoring eyes, ears, feet, or hands on one side of the body. A person who is cross-dominant can also be stronger on the opposite side of the body that they favor; for example, a right-handed person can be stronger on the left side. Cross-dominance can often be a problem when shooting or in activities that require aim, although athletes can still achieve success in sports that require accuracy, like passing in American football and shooting in basketball. In baseball In baseball a left-handed batter is about two st ...
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Baseball
Baseball is a bat-and-ball sport played between two teams of nine players each, taking turns batting and fielding. The game occurs over the course of several plays, with each play generally beginning when a player on the fielding team, called the pitcher, throws a ball that a player on the batting team, called the batter, tries to hit with a bat. The objective of the offensive team (batting team) is to hit the ball into the field of play, away from the other team's players, allowing its players to run the bases, having them advance counter-clockwise around four bases to score what are called " runs". The objective of the defensive team (referred to as the fielding team) is to prevent batters from becoming runners, and to prevent runners' advance around the bases. A run is scored when a runner legally advances around the bases in order and touches home plate (the place where the player started as a batter). The principal objective of the batting team is to hav ...
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Cricket
Cricket is a bat-and-ball game played between two teams of eleven players on a field at the centre of which is a pitch with a wicket at each end, each comprising two bails balanced on three stumps. The batting side scores runs by striking the ball bowled at one of the wickets with the bat and then running between the wickets, while the bowling and fielding side tries to prevent this (by preventing the ball from leaving the field, and getting the ball to either wicket) and dismiss each batter (so they are "out"). Means of dismissal include being bowled, when the ball hits the stumps and dislodges the bails, and by the fielding side either catching the ball after it is hit by the bat, but before it hits the ground, or hitting a wicket with the ball before a batter can cross the crease in front of the wicket. When ten batters have been dismissed, the innings ends and the teams swap roles. The game is adjudicated by two umpires, aided by a third umpire and match ref ...
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Boxing
Boxing (also known as "Western boxing" or "pugilism") is a combat sport in which two people, usually wearing protective gloves and other protective equipment such as hand wraps and mouthguards, throw punches at each other for a predetermined amount of time in a boxing ring. Although the term "boxing" is commonly attributed to "western boxing", in which only the fists are involved, boxing has developed in various ways in different geographical areas and cultures. In global terms, boxing is a set of combat sports focused on striking, in which two opponents face each other in a fight using at least their fists, and possibly involving other actions such as kicks, elbow strikes, knee strikes, and headbutts, depending on the rules. Some of the forms of the modern sport are western boxing, bare knuckle boxing, kickboxing, muay-thai, lethwei, savate, and sanda. Boxing techniques have been incorporated into many martial arts, military systems, and other combat sports. Whil ...
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Tennis
Tennis is a racket sport that is played either individually against a single opponent ( singles) or between two teams of two players each ( doubles). Each player uses a tennis racket that is strung with cord to strike a hollow rubber ball covered with felt over or around a net and into the opponent's court. The object of the game is to manoeuvre the ball in such a way that the opponent is not able to play a valid return. The player who is unable to return the ball validly will not gain a point, while the opposite player will. Tennis is an Olympic sport and is played at all levels of society and at all ages. The sport can be played by anyone who can hold a racket, including wheelchair users. The modern game of tennis originated in Birmingham, England, in the late 19th century as lawn tennis. It had close connections both to various field (lawn) games such as croquet and bowls as well as to the older racket sport today called real tennis. The rules of modern tennis have ...
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Genome-wide Association Study
In genomics, a genome-wide association study (GWA study, or GWAS), also known as whole genome association study (WGA study, or WGAS), is an observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated with a trait. GWA studies typically focus on associations between single-nucleotide polymorphisms (SNPs) and traits like major human diseases, but can equally be applied to any other genetic variants and any other organisms. When applied to human data, GWA studies compare the DNA of participants having varying phenotypes for a particular trait or disease. These participants may be people with a disease (cases) and similar people without the disease (controls), or they may be people with different phenotypes for a particular trait, for example blood pressure. This approach is known as phenotype-first, in which the participants are classified first by their clinical manifestation(s), as opposed to genotype-first. Each pe ...
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Locus (genetics)
In genetics, a locus (plural loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of protein-coding genes in a complete haploid set of 23 chromosomes is estimated at 19,000–20,000. Genes may possess multiple variants known as alleles, and an allele may also be said to reside at a particular locus. Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygous. The ordered list of loci known for a particular genome is called a gene map. Gene mapping is the process of determining the specific locus or loci responsible for producing a particular phenotype or biological trait. Association mapping, also known as "linkage disequilibrium mapping", is a method of ...
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Polygenic
A polygene is a member of a group of non- epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of Mendelian inheritance. The term "monozygous" is usually used to refer to a hypothetical gene as it is often difficult to distinguish the effect of an individual gene from the effects of other genes and the environment on a particular phenotype. Advances in statistical methodology and high throughput sequencing are, however, allowing researchers to locate candidate genes for the trait. In the case that such a gene is identified, it is referred to as a quantitative trait locus (QTL). These genes are generally pleiotropic as well. The genes that contribute to type 2 diabetes are thought to be mostly polygenes. In July 2016, scientists reported ide ...
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Left-right Asymmetry
Left-right asymmetry, (LR asymmetry) is the process in early embryonic development that breaks the normal symmetry in the bilateral embryo. In vertebrates, left-right asymmetry is established early in development at a structure called the left-right organizer (the name of which varies between species) and leads to activation of different signalling pathways on the left and right of the embryo. This in turn cause several organs in adults to develop LR asymmetry, such as the tilt of the heart, the different number lung lobes on each side of the body and the position of the stomach and spleen on the right side of the body. If this process does not occur correctly in humans it can result in the syndromes heterotaxy or situs inversus. LR asymmetry is pervasive throughout all animals, including invertebrates. Examples of invertebrate LR asymmetry include the large and small claws of the fiddler crab, asymmetrical gut coiling in ''Drosophila melanogaster,'' and dextral (clockwise) and ...
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Silvia Paracchini
Silvia Paracchini FRSE is a geneticist who researches the contribution of genetic variation to neurodevelopmental traits such as dyslexia and human handedness. Education As an undergraduate, Paracchini studied Biological Sciences at the University of Pavia, Italy. During this time she undertook an ERASMUS scholarship project at the Technical University of Denmark. She obtained her DPhil in Human Genetics from the University of Oxford in 2003. Career and research After obtaining her doctorate, Paracchini held a post-doctoral research position with the Wellcome Trust Centre for Human Genetics from 2003 to 2011. In 2011, she was awarded a Royal Society University Research Fellowship. Her research group at the University of St Andrews School of Medicine explores the genetic underpinnings of human behavioral traits like handedness, and neurodevelopment disorders like dyslexia by combining large genetic screenings for quantitative measures followed by gene function characterizatio ...
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