Rhadinovirus
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Rhadinovirus
''Rhadinovirus'' (synonyms: ''Rhadinoviridae'' and gamma-2 herpesviruses) is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Gammaherpesvirinae''. Humans and other mammals serve as natural hosts. There are 12 species in this genus. Diseases associated with this genus include: Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease, caused by '' Human gammaherpesvirus 8'' (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). The term rhadino comes from the Latin fragile, referring to the tendency of the viral genome to break apart when it is isolated. Species The genus consists of the following 12 species: * '' Ateline gammaherpesvirus 2'' * '' Ateline gammaherpesvirus 3'' * '' Bovine gammaherpesvirus 4'' * '' Cricetid gammaherpesvirus 2'' * '' Human gammaherpesvirus 8'' * '' Macacine gammaherpesvirus 5'' * '' Macacine gammaherpesvirus 8'' * '' Macacine gammaherpesvirus 11'' * '' Ma ...
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Herpesviridae
''Herpesviridae'' is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word ''ἕρπειν'' ( 'to creep'), referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster ( shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established ''Herpesvirus'' as a genus with 23 viruses among four groups. As of 2020, 115 species are recognized, all but one of which are in one of the three subfamilies. Herpesviruses can cause both latent and lytic infections. Nine herpesvirus types are known to primarily infect humans, at least five of which – herpes simplex viruses 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial herpes and genital herpes), varicella zoster virus (or HHV-3; the cause ...
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Gammaherpesvirinae
''Gammaherpesvirinae'' is a subfamily of viruses in the order ''Herpesvirales'' and in the family ''Herpesviridae''. Viruses in ''Gammaherpesvirinae'' are distinguished by reproducing at a more variable rate than other subfamilies of ''Herpesviridae''. Mammals serve as natural hosts. There are 43 species in this subfamily, divided among 7 genera with three species unassigned to a genus. Diseases associated with this subfamily include: HHV-4: infectious mononucleosis. HHV-8: Kaposi's sarcoma. Taxonomy Herpesviruses represent a group of double-stranded DNA viruses distributed widely within the animal kingdom. The family ''Herpesviridae'', which contains eight viruses that infect humans, is the most extensively studied group within this order and comprises three subfamilies, namely ''Alphaherpesvirinae'', ''Betaherpesvirinae'' and ''Gammaherpesvirinae''. Within the ''Gammaherpesvirinae'' there are a number of unclassified viruses including ''Cynomys herpesvirus 1'' (CynGHV-1)Nag ...
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Cricetid Gammaherpesvirus 2
''Cricetid gammaherpesvirus 2'' (CrHV-2) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Gammaherpesvirinae {{Virus-stub ...
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Bovine Gammaherpesvirus 4
''Bovine gammaherpesvirus 4'' (BoHV-4) is a member of the ''Herpesviridae'' family. It is part of the subfamily ''Gammaherpesvirinae'' and genus ''Rhadinovirus''. Infection is normally sub-clinical but can cause reproductive disease in cattle such as endometritis, vulvovaginitis and mastitis. Transmission is both vertical and horizontal. It can also be indirectly spread by fomites. Distribution is worldwide and the virus infects a range of ruminants, including bison, buffalo, sheep and goats. The disease may be referred to as a passenger virus. Clinical signs and diagnosis BoHV-4 infection is often subclinical, with no observable clinical signs. However the virus may cause abortion and retained foetal membranes, and if an infected fetus is born alive it may be weak. It can also cause mastitis in dairy cattle. It may be isolated from conjunctivitis and respiratory disease cases but it is unknown whether the EHV-4 is a primary or opportunistic pathogen in these cases. Diagno ...
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Murid Gammaherpesvirus 4
''Murid gammaherpesvirus 4'' (MuHV-4) is a species of virus in the genus ''Rhadinovirus''. It is a member of the subfamily ''Gammaherpesvirinae'' in the family ''Herpesviridae''. This species infects mice via the nasal passages and causes an acute infectious mononucleosis-like syndrome with elevated levels of leukocytes, and shifts in the relative proportion of lymphocytes along with the appearance of atypical mononuclear cells. ''Murid gammaherpesvirus 4'' currently serves as a model for study of human gammaherpesvirus pathogenesis Pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. The word comes from Greek πάθος ''pat .... Strains Seven strains of ''Murid gammaherpesvirus 4'' have been isolated, including the following six: * MuHV-Šum * MuHV-60 * MuHV-68 * MuHV-72 * MuHV-76 * MuHV-4556 References {{Taxonb ...
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Macacine Gammaherpesvirus 12
''Macacine gammaherpesvirus 12'' (McHV-12) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Gammaherpesvirinae {{Virus-stub ...
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Macacine Gammaherpesvirus 11
''Macacine gammaherpesvirus 11'' (McHV-11) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Gammaherpesvirinae {{Virus-stub ...
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Macacine Gammaherpesvirus 8
''Macacine gammaherpesvirus 8'' (McHV-8) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Gammaherpesvirinae {{Virus-stub ...
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Macacine Gammaherpesvirus 5
''Macacine gammaherpesvirus 5'' (McHV-5) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References External links * Gammaherpesvirinae {{Virus-stub ...
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Ateline Gammaherpesvirus 3
''Ateline gammaherpesvirus 3'' (AtHV-3) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Gammaherpesvirinae {{Virus-stub ...
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Saimiriine Gammaherpesvirus 2
''Saimiriine gammaherpesvirus 2'' (SaHV-2) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales''. See also * HSUR (''Herpesvirus saimiri'' U RNAs) * Squirrel monkey Squirrel monkeys are New World monkeys of the genus ''Saimiri''. ''Saimiri'' is the only genus in the subfamily Saimirinae. The name of the genus is of Tupi origin (''sai-mirím'' or ''çai-mbirín'', with ''sai'' meaning 'monkey' and ''mirím'' ... (''Saimiri'') References External links * Gammaherpesvirinae {{Virus-stub ...
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Ateline Gammaherpesvirus 2
''Ateline gammaherpesvirus 2'' (AtHV-2) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales''. See also * HSUR (''Herpesvirus saimiri'' U RNAs) * Spider monkey Spider monkeys are New World monkeys belonging to the genus ''Ateles'', part of the subfamily Atelinae, family Atelidae. Like other atelines, they are found in tropical forests of Central and South America, from southern Mexico to Brazil. The g ... (''Ateles'') References External links * Gammaherpesvirinae {{Virus-stub ...
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