Retracted Article On Neurotoxicity Of Ecstasy
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Retracted Article On Neurotoxicity Of Ecstasy
"Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA3,4-methylenedioxy-N-methylamphetamine (MDMA) is the chemical name for the psychotropic drug commonly known as "ecstasy". ("ecstasy")", is an article by George A. Ricaurte which was published in September 2002 in the peer-reviewed journal ''Science'', one of the world's top academic journals. It was later retracted; instead of using MDMA, methamphetamine had been used in the test. Original publication An editorial article on the paper indicated that researchers had observed dopaminergic neurotoxicity (death of neurons involved in dopamine pathways) in monkeys following MDMA injections, a finding which suggested that recreational users of MDMA may be at risk of developing neuropsychiatric disorders associated with dopamine dysfunction. Following the release of the paper, ''Science'' published a “News of the week” article by Constance Holden. The article noted that the results of ...
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MDMA
3,4-Methylenedioxymethamphetamine (MDMA), commonly seen in Tablet (pharmacy), tablet form (ecstasy) and crystal form (molly or mandy), is a potent empathogen–entactogen with stimulant properties primarily used for Recreational drug use, recreational purposes. The desired effects include altered Sense, sensations, increased energy, empathy, and pleasure. When taken by mouth, effects begin in 30 to 45 minutes and last 3 to 6 hours. MDMA was first developed in 1912 by Merck Group, Merck. It was used to enhance psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s. MDMA is commonly associated with dance party, dance parties, raves, and electronic dance music. It may be Cutting agent, mixed with other substances such as ephedrine, amphetamine, and methamphetamine. In 2016, about 21 million people between the ages of 15 and 64 used ecstasy (0.3% of the world population). This was broadly similar to the percentage of people who use cocaine ...
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San Francisco
San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of California cities by population, fourth most populous in California and List of United States cities by population, 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of , at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the County statistics of the United States, fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include ''SF'', ''San Fran'', ''The '', ''Frisco'', and '' ...
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New South Wales
) , nickname = , image_map = New South Wales in Australia.svg , map_caption = Location of New South Wales in AustraliaCoordinates: , subdivision_type = Country , subdivision_name = Australia , established_title = Before federation , established_date = Colony of New South Wales , established_title2 = Establishment , established_date2 = 26 January 1788 , established_title3 = Responsible government , established_date3 = 6 June 1856 , established_title4 = Federation , established_date4 = 1 January 1901 , named_for = Wales , demonym = , capital = Sydney , largest_city = capital , coordinates = , admin_center = 128 local government areas , admin_center_type = Administration , leader_title1 = Monarch , leader_name1 = Charles III , leader_title2 = Governor , leader_name2 = Margaret Beazley , leader_title3 = Premier , leader_name3 = Dominic Perrottet (Liberal) , national_representation = Parliament of Australia , national_representation_type1 = Senat ...
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Sydney
Sydney ( ) is the capital city of the state of New South Wales, and the most populous city in both Australia and Oceania. Located on Australia's east coast, the metropolis surrounds Sydney Harbour and extends about towards the Blue Mountains to the west, Hawkesbury to the north, the Royal National Park to the south and Macarthur to the south-west. Sydney is made up of 658 suburbs, spread across 33 local government areas. Residents of the city are known as "Sydneysiders". The 2021 census recorded the population of Greater Sydney as 5,231,150, meaning the city is home to approximately 66% of the state's population. Estimated resident population, 30 June 2017. Nicknames of the city include the 'Emerald City' and the 'Harbour City'. Aboriginal Australians have inhabited the Greater Sydney region for at least 30,000 years, and Aboriginal engravings and cultural sites are common throughout Greater Sydney. The traditional custodians of the land on which modern Sydney stands are ...
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Australian Broadcasting Corporation
The Australian Broadcasting Corporation (ABC) is the national broadcaster of Australia. It is principally funded by direct grants from the Australian Government and is administered by a government-appointed board. The ABC is a publicly-owned body that is politically independent and fully accountable, with its charter enshrined in legislation, the ''Australian Broadcasting Corporation Act 1983''. ABC Commercial, a profit-making division of the corporation, also helps to generate funding for content provision. The ABC was established as the Australian Broadcasting Commission on 1 July 1932 by an act of federal parliament. It effectively replaced the Australian Broadcasting Company, a private company established in 1924 to provide programming for A-class radio stations. The ABC was given statutory powers that reinforced its independence from the government and enhanced its news-gathering role. Modelled after the British Broadcasting Corporation (BBC), which is funded by a tel ...
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ABC News (Australia)
ABC News, or ABC News and Current Affairs, is a public news service produced by the Australian Broadcasting Corporation. Broadcasting within Australia and the rest of the world, the service covers both local and world affairs. The division of the organisation, which is called ABC News, Analysis and Investigations. is responsible for all news-gathering and coverage across the Australian Broadcasting Corporation's various television, radio, and online platforms. Some of the services included under the auspices of the division are the ABC News TV channel (formerly ABC News 24); the long-running radio news programs, '' AM'', '' The World Today'', and '' PM''; ABC NewsRadio, a 24-hour continuous news radio channel; and radio news bulletins and programs on ABC Local Radio, ABC Radio National, ABC Classic FM, and Triple J. ABC News Online has an extensive online presence which includes many written news reports and videos available via ABC Online, an ABC News mobile app (ABC Liste ...
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ABC Science
ABC News, or ABC News and Current Affairs, is a public news service produced by the Australian Broadcasting Corporation. Broadcasting within Australia and the rest of the world, the service covers both local and world affairs. The division of the organisation, which is called ABC News, Analysis and Investigations. is responsible for all news-gathering and coverage across the Australian Broadcasting Corporation's various television, radio, and online platforms. Some of the services included under the auspices of the division are the ABC News TV channel (formerly ABC News 24); the long-running radio news programs, '' AM'', '' The World Today'', and '' PM''; ABC NewsRadio, a 24-hour continuous news radio channel; and radio news bulletins and programs on ABC Local Radio, ABC Radio National, ABC Classic FM, and Triple J. ABC News Online has an extensive online presence which includes many written news reports and videos available via ABC Online, an ABC News mobile app (ABC Lis ...
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Maryland
Maryland ( ) is a state in the Mid-Atlantic region of the United States. It shares borders with Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware and the Atlantic Ocean to its east. Baltimore is the largest city in the state, and the capital is Annapolis. Among its occasional nicknames are '' Old Line State'', the ''Free State'', and the '' Chesapeake Bay State''. It is named after Henrietta Maria, the French-born queen of England, Scotland, and Ireland, who was known then in England as Mary. Before its coastline was explored by Europeans in the 16th century, Maryland was inhabited by several groups of Native Americans – mostly by Algonquian peoples and, to a lesser degree, Iroquoian and Siouan. As one of the original Thirteen Colonies of England, Maryland was founded by George Calvert, 1st Baron Baltimore, a Catholic convert"George Calvert and Cecilius Calvert, Barons Baltimore" William Hand Browne, ...
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Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ...
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Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consistently ranks among the most prestigious universities in the United States and the world. The university was named for its first benefactor, the American entrepreneur and Quaker philanthropist Johns Hopkins. Hopkins' $7 million bequest to establish the university was the largest Philanthropy, philanthropic gift in U.S. history up to that time. Daniel Coit Gilman, who was inaugurated as :Presidents of Johns Hopkins University, Johns Hopkins's first president on February 22, 1876, led the university to revolutionize higher education in the U.S. by integrating teaching and research. In 1900, Johns Hopkins became a founding member of the American Association of Universities. The university has led all Higher education in the U ...
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Urban Legends About Illegal Drugs
Many urban legends and misconceptions about drugs have been created and circulated among young people and the general public, with varying degrees of veracity. These are commonly repeated by organizations which oppose all classified drug use, often causing the true effects and dangers of drugs to be misunderstood and less scrutinized. The most common subjects of such false beliefs are LSD, cannabis, and MDMA. These misconceptions include misinformation about adulterants or other black market issues, as well as alleged effects of the pure substances. Lysergic acid diethylamide (LSD) Some of the strangest urban legends told are those about lysergic acid diethylamide (LSD), a potent psychedelic drug that gained popularity in several countries in the 1960s and 1970s, and experienced a resurgence in the mid 2010s to present. The drug's relation to the 1960s counterculture was likely part of the reason for such legends. Babysitter places baby in the oven while high on LSD This is ...
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Leslie Iversen
Leslie Lars Iversen (31 October 1937 – 30 July 2020), was a British pharmacologist, known for his work on the neurochemistry of neurotransmission. Career and research From 1971 to 1982, Iversen was Director of the MRC Neurochemical Pharmacology Unit in Cambridge. Between 1982 and 1995 he worked as Director of the Merck, Sharp & Dohme Neuroscience Research Centre. In 1995 he became Visiting Professor of Pharmacology at the University of Oxford. In 2010 he was accused of plagiarism. Consequently one of his books now credits the original author of the plagiarized work. Awards and honours He was elected a Fellow of the Royal Society (FRS) in 1980 and gave the Society's Ferrier Lecture in 1983. He was appointed a Commander of the Order of the British Empire (CBE) in the 2013 New Year Honours The New Year Honours 2013 were appointments by some of the 16 Commonwealth realms to Orders and decorations of the Commonwealth realms, various orders and honours to recognise and ...
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