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Ruhugu Virus
Ruhugu virus, scientific name ''Rubivirus ruteetense'', is a species of virus in the genus '' Rubivirus''. It was discovered in 2019 in healthy Ugandan bats. It belongs to the family of '' Matonaviridae'', a single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid. Discovery and habitat Ruhugu virus was discovered in healthy Cyclops roundleaf bats in Kibale National Park, Uganda. prior to the COVID-19 pandemic, while looking for coronaviruses carried by bats. Etymology Ruhugu virus was named after the Ruteete region of Uganda and the word in the local Tooro language, which describes "the flapping of bat wings in the hollow of a tree: obuhuguhugu" Structure Ruhugu virus is closely related to Rubella virus Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy. Rub ...
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Genus
Genus ( plural genera ) is a taxonomic rank used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In the hierarchy of biological classification, genus comes above species and below family (taxonomy), family. In binomial nomenclature, the genus name forms the first part of the binomial species name for each species within the genus. :E.g. ''Panthera leo'' (lion) and ''Panthera onca'' (jaguar) are two species within the genus ''Panthera''. ''Panthera'' is a genus within the family Felidae. The composition of a genus is determined by taxonomy (biology), taxonomists. The standards for genus classification are not strictly codified, so different authorities often produce different classifications for genera. There are some general practices used, however, including the idea that a newly defined genus should fulfill these three criteria to be descriptively useful: # monophyly – all descendants ...
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Rubivirus
''Rubivirus'' is a genus of virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...es. It contains three species. Taxonomy The following three species are assigned to the genus: * '' Rubivirus rubellae'', commonly called rubella virus * '' Rubivirus ruteetense'', commonly called ruhugu virus * '' Rubivirus strelense'', commonly called rustrela virus References {{Taxonbar, from1=Q18822330, from2=Q69848812 Virus genera ...
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Family (biology)
Family ( la, familia, plural ') is one of the eight major hierarchical taxonomic ranks in Linnaean taxonomy. It is classified between order and genus. A family may be divided into subfamilies, which are intermediate ranks between the ranks of family and genus. The official family names are Latin in origin; however, popular names are often used: for example, walnut trees and hickory trees belong to the family Juglandaceae, but that family is commonly referred to as the "walnut family". What belongs to a family—or if a described family should be recognized at all—are proposed and determined by practicing taxonomists. There are no hard rules for describing or recognizing a family, but in plants, they can be characterized on the basis of both vegetative and reproductive features of plant species. Taxonomists often take different positions about descriptions, and there may be no broad consensus across the scientific community for some time. The publishing of new data and opini ...
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Matonaviridae
''Rubivirus'' is a genus of virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...es. It contains three species. Taxonomy The following three species are assigned to the genus: * '' Rubivirus rubellae'', commonly called rubella virus * '' Rubivirus ruteetense'', commonly called ruhugu virus * '' Rubivirus strelense'', commonly called rustrela virus References {{Taxonbar, from1=Q18822330, from2=Q69848812 Virus genera ...
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Sense (molecular Biology)
In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids. Depending on the context, sense may have slightly different meanings. For example, negative-sense strand of DNA is equivalent to the template strand, whereas the positive-sense strand is the non-template strand whose nucleotide sequence is equivalent to the sequence of the mRNA transcript. DNA sense Because of the complementary nature of base-pairing between nucleic acid polymers, a double-stranded DNA molecule will be composed of two strands with sequences that are reverse complements of each other. To help molecular biologists specifically identify each strand individually, the two strands are usually differentiated as the "sense" strand and the "antisense" strand. An individual strand of DNA is referred to as positive-sense (also positive (+) or simply sense) ...
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Icosahedron
In geometry, an icosahedron ( or ) is a polyhedron with 20 faces. The name comes and . The plural can be either "icosahedra" () or "icosahedrons". There are infinitely many non- similar shapes of icosahedra, some of them being more symmetrical than others. The best known is the (convex, non- stellated) regular icosahedron—one of the Platonic solids—whose faces are 20 equilateral triangles. Regular icosahedra There are two objects, one convex and one nonconvex, that can both be called regular icosahedra. Each has 30 edges and 20 equilateral triangle faces with five meeting at each of its twelve vertices. Both have icosahedral symmetry. The term "regular icosahedron" generally refers to the convex variety, while the nonconvex form is called a ''great icosahedron''. Convex regular icosahedron The convex regular icosahedron is usually referred to simply as the ''regular icosahedron'', one of the five regular Platonic solids, and is represented by its Schläfli symbol , con ...
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Capsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may consist of one or more ...
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Cyclops Roundleaf Bat
The cyclops roundleaf bat or cyclops leaf-nosed bat (''Doryrhina cyclops'') is a species of bat in the family Hipposideridae found in the forests of equatorial Africa. Description Cyclops roundleaf bats are relatively small, with adults ranging from in total length, including a tail approximately long. With an average weight of , females are significantly larger than males at just . The body is covered in thick woolly fur, which is a dark brown in colour, grizzled with lighter flecks on the tips of the hairs. The wings are very dark brown, almost black, in colour. The ears are long and narrowly pointed. The nose-leaf has a distinctive shape, with a rounded horseshoe shape over the muzzle and a posterior leaf with two projections on each side. Both parts of the leaf also possess small club-like structures projecting from their mid-line. The "cyclops" part of the bat's name comes from the presence of a narrow circular opening in the centre of the forehead, just behind, and normal ...
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Kibale National Park
Kibale Forest National Park is a national park in western Uganda, protecting moist evergreen rainforest. It is in size and ranges between and in elevation. Despite encompassing primarily moist evergreen forest, it contains a diverse array of landscapes.McGrew, William, ''et al''. ''Great Ape Societies''. Cambridge University Press, 1996. Print. Kibale is one of the last remaining expanses to contain both lowland and montane forests. In eastern Africa, it sustains the last significant expanse of pre-montane forest. The park was gazetted in 1932 and formally established in 1993 to protect a large area of forest previously managed as a logged forest reserve. The park forms a continuous forest with Queen Elizabeth National Park. This adjoining of the parks creates a wildlife corridor. It is an important ecotourism and safari destination, well-known for its population of habituated chimpanzees and twelve other species of primates. It is also the location of the Makerere University ...
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Coronavirus
Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, they cause respiratory tract infections that can range from mild to lethal. Mild illnesses in humans include some cases of the common cold (which is also caused by other viruses, predominantly rhinoviruses), while more lethal varieties can cause SARS, MERS and COVID-19, which is causing the ongoing pandemic. In cows and pigs they cause diarrhea, while in mice they cause hepatitis and encephalomyelitis. Coronaviruses constitute the subfamily ''Orthocoronavirinae'', in the family ''Coronaviridae'', order '' Nidovirales'' and realm '' Riboviria''. They are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses ranges from approximately 26 to 32 kilobases, one of the largest among RNA viruses. They have characteristic club-shaped spikes that project from their surface, which in electr ...
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Tooro Language
Tooro, or ''Rutooro'', is a Bantu language spoken mainly by the Toro people (''Batooro'') from the Toro Kingdom region of western Uganda. There are three main areas where Rutooro as a language is mainly used and they are Kabarole District, Kyenjojo District and Kyegegwa District. Rutooro is unique among Bantu languages as it lacks lexical tone. It is most closely related to Runyoro. See also * Runyakitara language Runyakitara is a standardized language based on four closely related languages of western Uganda: * Nyoro or ''Runyoro'' * Kiga (Chiga) or ''Rukiga'' * Nkore or ''Runyankole'' * Tooro or ''Rutooro'' Jouni Filip Maho's 2009 New Updated Guthrie ... Yega Orutooro References Languages of Uganda Nyoro-Ganda languages {{Uganda-stub ...
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Rubella Virus
Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy. Rubella virus, scientific name ''Rubivirus rubellae'', is a member of the genus '' Rubivirus'' and belongs to the family of ''Matonaviridae'', whose members commonly have a genome of single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid. the molecular basis for the causation of congenital rubella syndrome was not yet completely clear, but ''in vitro'' studies with cell lines showed that rubella virus has an apoptotic effect on certain cell types. There is evidence for a p53-dependent mechanism. Taxonomy Rubella virus (''Rubivirus rubellae'') is assigned to the ''Rubivirus'' genus. ''Matonaviridae'' family Until 2018, Rubiviruses were classified as part of the family ''Togaviridae'', but have since been changed ...
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