Rubefacients
A rubefacient is a substance for topical application that produces redness of the skin, e.g. by causing dilation of the capillaries and an increase in blood circulation. They have sometimes been used to relieve acute or chronic pain, but there is limited evidence as to their efficacy,Mason et al. 200''Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain''BMJ 328:995 and as of 2014 the best evidence does not support using gels and creams containing rubefacients for this purpose. Examples Common medicinal rubefacients include: *Salicylates, such as methyl salicylate (oil of wintergreen) *Nicotinate esters *Capsaicin, derived from chili pepper, ''Capsicum minimum'', "incites irritation without rubefaction" *Isopropanol (rubbing alcohol) *Menthol *Minoxidil * Thurfyl nicotinate (Trafuril) Common herbal rubefacients include:{{citation needed, date=October 2016 *Cloves (''Syzygium aromaticum'') *Garlic (''Allium sativum'' ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Methyl Salicylate
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula C8H8O3. It is the methyl ester of salicylic acid. It is a colorless, viscous liquid with a sweet, fruity odor reminiscent of root beer, but often associatively called "minty", as it is an ingredient in mint candies. It is produced by many species of plants, particularly wintergreens. It is also produced synthetically, used as a fragrance and as a flavoring agent. Biosynthesis and occurrence Methyl salicylate was first isolated (from the plant ''Gaultheria procumbens'') in 1843 by the French chemist Auguste André Thomas Cahours (1813–1891), who identified it as an ester of salicylic acid and methanol. The biosynthesis of methyl salicylate arises via the hydroxylation of benzoic acid by a cytochrome P450 followed by methylation by a methylase enzyme. Methyl salicylate as a plant metabolite Many plants produce methyl salicylate in small quantities. Methyl salicylate levels are o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Liniment
Liniment (from la, linere, meaning "to anoint"), also called embrocation and heat rub, is a medicated topical preparation for application to the skin. Some liniments have viscosity similar to that of water; others are lotion or balm; still others are in transdermal patches, soft solid sticks, and sprays. Liniment usually is rubbed in to the skin, which the active ingredients penetrate. Liniments are typically sold to relieve pain and stiffness, such as from muscular aches and strains, and arthritis. These are typically formulated from alcohol, acetone, or similar quickly evaporating solvents and contain counterirritant aromatic chemical compounds, such as methyl salicilate, benzoin resin, menthol, and capsaicin. They produce a feeling of warmth within the muscle of the area they are applied to, typically acting as rubefacients via a counterirritant effect. Methyl salicylate, which is the analgesic ingredient in some heat rubs, can be toxic if used to excess. Heating pads are als ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Capsaicin
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) ( or ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a chemical irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related alkaloids are called capsaicinoids and are produced as secondary metabolites by chili peppers, probably as deterrents against certain mammals and fungi.What Made Chili Peppers So Spicy? Talk of the Nation, 15 August 2008. Pure capsaicin is a , colorless, highly [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Topical
A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. Many topical medications are epicutaneous, meaning that they are applied directly to the skin. Topical medications may also be inhalational, such as asthma medications, or applied to the surface of tissues other than the skin, such as eye drops applied to the conjunctiva, or ear drops placed in the ear, or medications applied to the surface of a tooth. The word ''topical'' derives from Greek τοπικός ''topikos'', "of a place". Justification Topical drug delivery is a route of administering drugs via the skin to provide topical therapeutic effects. As skin is one of the largest and most superficial organs in the human body, pharmacists utilise it to deliver various drugs. This ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Syzygium Aromaticum
Cloves are the aromatic flower buds of a tree in the family Myrtaceae, ''Syzygium aromaticum'' (). They are native to the Maluku Islands (or Moluccas) in Indonesia, and are commonly used as a spice, flavoring or fragrance in consumer products, such as toothpaste, soaps, or cosmetics. Cloves are available throughout the year owing to different harvest seasons across various countries. Etymology The word ''clove'', first used in English in the 15th century, derives via Middle English ''clow of gilofer'', Anglo-French ''clowes de gilofre'' and Old French ''clou de girofle'', from the Latin word ''clavus'' "nail". The related English word ''gillyflower'', originally meaning "clove", derives via said Old French ''girofle'' and Latin ''caryophyllon'', from the Greek ''karyophyllon'' "clove", literally "nut leaf". Botanical features The clove tree is an evergreen that grows up to tall, with large leaves and crimson flowers grouped in terminal clusters. The flower buds initially h ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mentha Piperita
Peppermint (''Mentha'' × ''piperita'') is a hybrid species of mint, a cross between watermint and spearmint. Indigenous to Europe and the Middle East, the plant is now widely spread and cultivated in many regions of the world.Euro+Med Plantbase Project''Mentha'' × ''piperita''/ref> It is occasionally found in the wild with its parent species.Flora of NW Europe''Mentha'' × ''piperita'' Although the genus ''Mentha'' comprises more than 25 species, the one in most common use is peppermint. While Western peppermint is derived from ''Mentha × piperita'', Chinese peppermint, or ''bohe'', is derived from the fresh leaves of ''M. haplocalyx''. ''M. × piperita'' and ''M. haplocalyx'' are both recognized as plant sources of menthol and menthone, and are among the oldest herbs used for both culinary and medicinal products. Botany Peppermint was first described in 1753 by Carl Linnaeus from specimens that had been collected in England; he treated it as a species,Linnaeus, C. (175 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ruta Graveolens
''Ruta graveolens'', commonly known as rue, common rue or herb-of-grace, is a species of '' Ruta'' grown as an ornamental plant and herb. It is native to the Balkan Peninsula. It is grown throughout the world in gardens, especially for its bluish leaves, and sometimes for its tolerance of hot and dry soil conditions. It is also cultivated as a culinary herb, and to a lesser extent as an insect repellent and incense. Etymology The specific epithet ''graveolens'' refers to the strong-smelling leaves.J. D. Douglas and Merrill C. Tenney Description Rue is a woody, perennial shrub. Its leaves are oblong, blue green and arranged pinnate; they release a strong aroma when they are bruised. The flowers are small with 4 to 5 dull yellow petals in clusters. They bear brown seed capsules when pollinated. Uses Traditional use In the ancient Roman world, the naturalists Pedanius Dioscorides and Pliny the Elder recommended that rue be combined with the poisonous shrub oleander to ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rosmarinus Officinalis
''Salvia rosmarinus'' (), commonly known as rosemary, is a shrub with fragrant, evergreen, needle-like leaves and white, pink, purple, or blue flowers, native to the Mediterranean region. Until 2017, it was known by the scientific name ''Rosmarinus officinalis'' (), now a synonym. It is a member of the sage family Lamiaceae, which includes many other medicinal and culinary herbs. The name "rosemary" derives from Latin ("dew of the sea"). Rosemary has a fibrous root system. Description Rosemary is an aromatic evergreen shrub with leaves similar to hemlock needles. It is native to the Mediterranean and Asia, but is reasonably hardy in cool climates. Special cultivars like 'Arp' can withstand winter temperatures down to about . It can withstand droughts, surviving a severe lack of water for lengthy periods. In some parts of the world, it is considered a potentially invasive species. The seeds are often difficult to start, with a low germination rate and relatively slow growth, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Urtica Dioica
''Urtica dioica'', often known as common nettle, burn nettle, stinging nettle (although not all plants of this species sting) or nettle leaf, or just a nettle or stinger, is a herbaceous perennial flowering plant in the family Urticaceae. Originally native to Europe, much of temperate Asia and western North Africa, it is now found worldwide, including New Zealand and North America. The species is divided into six subspecies, five of which have many hollow stinging hairs called trichomes on the leaves and stems, which act like hypodermic needles, injecting histamine and other chemicals that produce a stinging sensation upon contact ("contact urticaria", a form of contact dermatitis). The plant has a long history of use as a source for traditional medicine, food, tea, and textile raw material in ancient (such as Saxon) and modern societies. Description ''Urtica dioica'' is a dioecious, herbaceous, perennial plant, tall in the summer and dying down to the ground in winter. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brassica Nigra
''Brassica nigra'', or black mustard, is an annual plant cultivated for its dark-brown-to-black seeds, which are commonly used as a spice. It is native to tropical regions of North Africa, temperate regions of Europe, and parts of Asia. Description It is an upright plant, with large stalked leaves. They are covered with hairs or bristles at the base, but on the stem smoother. It can reach up to tall in moist fertile soil. It blooms in summer, from May (in the UK) onwards. The flowers have four yellow petals, which are twice as long as the sepals. Each stem has around four flowers at the top, forming a ring around the stem. Later, the plant forms long seed pods, that contain four rounded seeds. Taxonomy It was formally described by Karl Koch in "Deutschl. Fl." (or Deutschlands Flora) ed.3 on page 713 in 1833. This was based on a description by the Swedish botanist Carl Linnaeus. The Latin specific epithet ''nigra'' is derived from the Latin word for black. This is due to th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brassica Alba
White mustard (''Sinapis alba'') is an annual plant of the family Brassicaceae. It is sometimes also referred to as ''Brassica alba'' or ''B. hirta''. Grown for its seeds, used to make the condiment mustard, as fodder crop, or as a green manure, it is now widespread worldwide, although it probably originated in the Mediterranean region. Description White mustard is an annual, growing to high with stalkless pinnate leaves, similar to ''Sinapis arvensis''. Distribution Most common in Europe, North Africa, the Middle East and Central Asia, it can be found worldwide. It has been found as far north as Greenland, and naturalized throughout Great Britain and Ireland. Culinary uses The yellow flowers of the plant produce glabrous or sparsely bristled seed pods. Each fruit (silique) contains roughly a half dozen seeds. The plants are harvested for their seeds just prior to the seed pods becoming ripe and bursting open (dehiscing). White mustard seeds are hard spheroid seeds, usually ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cochlearia
''Cochlearia'' (scurvy-grass or spoonwort) is a genus of about 30 species of annual and perennial herbs in the family Brassicaceae. They are widely distributed in temperate and arctic areas of the northern hemisphere, most commonly found in coastal regions, on cliff-tops and salt marshes where their high tolerance of salt enables them to avoid competition from larger, but less salt-tolerant plants; they also occur in alpine habitats in mountains and tundra. They form low, rounded or creeping plants, typically 5–20 cm tall. The leaves are smoothly rounded, roughly spoon-shaped (the scientific name ''Cochlearia'' derives from the Latinized form, ''cocleare'', of the Greek κοχλιάριον, ''kokhliárion'', a spoon; this a diminutive of κόχλος, ''kókhlos'', seashell), or in some species, lobed; typically 1–5 cm long, and with a fleshy texture. The flowers are white with four petals and are borne in short racemes. Selected species About 30 species are usu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |