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Roger Gosden
Roger Gordon Gosden (born 23 September 1948) is a British-American physiologist in the field of female reproductive medicine. His scientific research focused on understanding the basic biology of development and senescence of ovaries in women, including mathematically modeling those processes. He did important translational research on ovarian tissue cryopreservation and transplantation. Early life and education Gosden was born on 23 September 1948 at Ryde on the Isle of Wight, the son of Gordon Gosden and Peggy Gosden, ''née'' Butcher. He went to Chislehurst and Sidcup Grammar School in Sidcup, Kent, and then took a BSc from the University of Bristol in 1970. He did post-graduate work under Robert Edwards at Darwin College, Cambridge, where he graduated PhD in 1974 with a thesis on ''Reproductive senescence in female rodents''. Scientific career Gosden was a lecturer in physiology at the University of Edinburgh Medical School from 1976 to 1994, a professor of reproducti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ryde
Ryde is an English seaside town and civil parish on the north-east coast of the Isle of Wight. The built-up area had a population of 23,999 according to the 2011 Census and an estimate of 24,847 in 2019. Its growth as a seaside resort came after the villages of Upper Ryde and Lower Ryde were merged in the 19th century, as can still be seen in the town's central and seafront architecture. The resort's expansive sands are revealed at low tide. Their width means the regular ferry service to the mainland requires a long listed pier – the fourth longest in the United Kingdom, and the oldest surviving. History In 1782 numerous bodies of men, women and children from HMS ''Royal George'', which sank suddenly at Spithead, were washed ashore at Ryde. Many were buried on land that is now occupied by the Esplanade. A memorial to them was erected in June 2004. There are a series of Regency and Victorian buildings in the town with important buildings such as All Saints' Church, designed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Senescence
Senescence () or biological aging is the gradual deterioration of functional characteristics in living organisms. The word ''senescence'' can refer to either cellular senescence or to senescence of the whole organism. Organismal senescence involves an increase in death rates and/or a decrease in fecundity with increasing age, at least in the latter part of an organism's life cycle. Senescence is the inevitable fate of almost all multicellular organisms with germ-soma separation, but it can be delayed. The discovery, in 1934, that calorie restriction can extend lifespan by 50% in rats, and the existence of species having negligible senescence and potentially immortal organisms such as '' Hydra'', have motivated research into delaying senescence and thus age-related diseases. Rare human mutations can cause accelerated aging diseases. Environmental factors may affect aging – for example, overexposure to ultraviolet radiation accelerates skin aging. Different parts of the body ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embryonic Stem Cell
Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre- implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre-implantation stage have the same moral considerations as embryos in the post-implantation stage of development. Researchers are currently focusing heavily on the therapeutic potential of embryonic stem cells, with clinical use being the goal for many laboratories. Potential uses include the treatment of diabetes and heart disease. The cells are being studied to be used as clinical therapies, models of genetic disorders, and cellular/DNA repair. However, adverse effects in the research and clinical processes such as tumors and unw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weill Cornell Medicine
The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with NewYork-Presbyterian Hospital, Weill Cornell Medical Center, Hospital for Special Surgery, Memorial Sloan Kettering Cancer Center, and Rockefeller University, all of which are located nearby on York Avenue. Weill Cornell's clinical affiliates rank highly, with the NewYork-Presbyterian Hospital ranked #1 in the region and #4 in the nation, the Hospital for Special Surgery ranked #1 in the nation for orthopedics and the Memorial Sloan Kettering Center #2 for cancer. Memorial Sloan Kettering Cancer Center and Rockefeller University joined Weill Cornell to establish the Tri-Institutional MD–PhD Program in 1991. In 2001, the school opened a campus in Qatar. Weill Cornell has also been affiliated with Houston Methodist Hospital since 2004. On Se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Independent
''The Independent'' is a British online newspaper. It was established in 1986 as a national morning printed paper. Nicknamed the ''Indy'', it began as a broadsheet and changed to tabloid format in 2003. The last printed edition was published on Saturday 26 March 2016, leaving only the online edition. The newspaper was controlled by Tony O'Reilly's Irish Independent News & Media from 1997 until it was sold to the Russian oligarch and former KGB Officer Alexander Lebedev in 2010. In 2017, Sultan Muhammad Abuljadayel bought a 30% stake in it. The daily edition was named National Newspaper of the Year at the 2004 British Press Awards. The website and mobile app had a combined monthly reach of 19,826,000 in 2021. History 1986 to 1990 Launched in 1986, the first issue of ''The Independent'' was published on 7 October in broadsheet format.Dennis Griffiths (ed.) ''The Encyclopedia of the British Press, 1422–1992'', London & Basingstoke: Macmillan, 1992, p. 330 It was produc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Narrative Hook
A narrative hook (or just hook) is a literary technique in the opening of a story that "hooks" the reader's attention so that they will keep on reading. The "opening" may consist of several paragraphs for a short story, or several pages for a novel, but ideally it is the opening sentence in the book. Examples Opening a novel with startling, dramatic action or an ominous description can function as a narrative hook. Ovid's ''Fasti (poem), Fasti'' employs narrative hooks in the openings of each book, including a description of a bloody ghost and an ominous exchange between the characters Callisto and Diana. A narrative hook can also take the form of a short, often shocking passage discussing an important event in the life of one of the work's characters. The device establishes Narration, character voice and introduces a theme of the work. In Anna Quindlen's ''Black and Blue (Quindlen novel), Black and Blue'', the opening sentence recounts the first time the protagonist endured abus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reproductive Sciences
''Reproductive Sciences'' is a peer-reviewed medical journal that publishes papers in the fields of obstetrics and gynecology. The co- editors-in-chief are Ayman Al-Hendy and Seung-Yup Ku. It was established in 1994 and is currently published by Springer Nature on behalf of the Society for Reproductive Investigation. Abstracting and indexing The journal is abstracted and indexed in Scopus and the Social Sciences Citation Index The Social Sciences Citation Index (SSCI) is a commercial citation index product of Clarivate Analytics. It was originally developed by the Institute for Scientific Information from the Science Citation Index. The Social Sciences Citation Index is .... According to the '' Journal Citation Reports'', its 2013 impact factor is 2.23, ranking it 17th out of 30 journals in the category "Reproductive Biology" and 26th out of 79 journals in the category "Obstetrics & Gynecology". References External links * {{Official website, https://www.springer.com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thesis (academic)
A thesis ( : theses), or dissertation (abbreviated diss.), is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings.International Standard ISO 7144: DocumentationâPresentation of theses and similar documents International Organization for Standardization, Geneva, 1986. In some contexts, the word "thesis" or a cognate is used for part of a bachelor's or master's course, while "dissertation" is normally applied to a doctorate. This is the typical arrangement in American English. In other contexts, such as within most institutions of the United Kingdom and Republic of Ireland, the reverse is true. The term graduate thesis is sometimes used to refer to both master's theses and doctoral dissertations. The required complexity or quality of research of a thesis or dissertation can vary by country, university, or program, and the required minimum study period may thus vary significantly in dur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Darwin College, Cambridge
Darwin College is a constituent college of the University of Cambridge. Founded on 28 July 1964, Darwin was Cambridge University's first graduate-only college, and also the first to admit both men and women. The college is named after one of the university's most famous families and alumni, that of Charles Darwin. The Darwin family previously owned some of the land, Newnham Grange, on which the college now stands. The college has between 600 and 700 students, mostly studying for PhD or MPhil degrees with strengths in the sciences, humanities, and law. About half the students come from outside the United Kingdom, representing 80 nationalities as of 2016. Darwin is the largest graduate college of Cambridge. Darwin's sister college at Oxford University is Wolfson College. Members of Darwin College are termed ''Darwinians''. The college has several distinguished alumni including prominent heads of government and state, politicians, diplomats, and scientists from various countr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Edwards (physiologist)
Sir Robert Geoffrey Edwards (27 September 1925 – 10 April 2013) was a British physiologist and pioneer in reproductive medicine, and in-vitro fertilisation (IVF) in particular. Along with obstetrician and gynaecologist Patrick Steptoe and nurse Jean Purdy, Edwards successfully pioneered conception through IVF, which led to the birth of Louise Brown on 1978. They founded the first IVF programme for infertile patients and trained other scientists in their techniques. Edwards was the founding editor-in-chief of ''Human Reproduction'' in 1986. In 2010, he was awarded the Nobel Prize in Physiology or Medicine "for the development of in vitro fertilization". Education and early career Edwards was born in Batley, Yorkshire, and attended Manchester Central High School on Whitworth Street in central Manchester, after which he served in the British Army, and then completed his undergraduate studies in biology, graduating with an Ordinary degree at Bangor University. He studied at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sidcup
Sidcup is an area of south-east London, England, primarily in the London Borough of Bexley. It is south-east of Charing Cross, bordering the London Boroughs of London Borough of Bromley, Bromley and Royal Borough of Greenwich, Greenwich. Before the creation of Greater London in 1965, it was in the Historic counties of England, historical county of Kent. The name is thought to be derived from meaning "seat shaped or flat topped hill"; it had its earliest recorded use in 1254. The population of Sidcup, including its neighbourhoods Foots Cray, North Cray, Albany Park, Bexley, Albany Park, Longlands, Ruxley, Blackfen and Lamorbey, was 43,109 in 2011. History Origins Sidcup originated as a tiny hamlet on the road from Maidstone to London. According to Edward Hasted, "Thomas de Sedcopp was owner of this estate in the 35th year of king Henry VI of England, Henry VI. [i.e. in the 1450s] as appears by his deed." Hasted described Sidcup in the latter part of the 18th century as "a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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