Robert L. Hill (biochemist)
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Robert L. Hill (biochemist)
Robert L. Hill (1928-2012) was a biochemist who spent most of his career on the faculty at Duke University School of Medicine, from which he retired as the James B. Duke Professor Emeritus. Hill's research focused on the chemistry of enzymes, with particular specialization in glycosyltransferases and glycobiology. Hill was elected to the American Academy of Arts and Sciences in 1974, the National Academy of Sciences in 1975, the Institute of Medicine in 1978. He served on the editorial board of the scientific journal ''Journal of Biological Chemistry'' beginning in 1965 and as associate editor from 1988 to 2012, where he initiated a regular feature series called "Classics" in which the journal reprinted selected papers of high historical significance. Hill died on November 29, 2012. Early life and education Hill was born in Kansas City, Missouri in 1928. He was an undergraduate at the University of Kansas and received a B.S. in chemistry in 1949. He remained there for graduate w ...
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Kansas City, Missouri
Kansas City (abbreviated KC or KCMO) is the largest city in Missouri by population and area. As of the 2020 census, the city had a population of 508,090 in 2020, making it the 36th most-populous city in the United States. It is the central city of the Kansas City metropolitan area, which straddles the Missouri–Kansas state line and has a population of 2,392,035. Most of the city lies within Jackson County, with portions spilling into Clay, Cass, and Platte counties. Kansas City was founded in the 1830s as a port on the Missouri River at its confluence with the Kansas River coming in from the west. On June 1, 1850, the town of Kansas was incorporated; shortly after came the establishment of the Kansas Territory. Confusion between the two ensued, and the name Kansas City was assigned to distinguish them soon after. Sitting on Missouri's western boundary with Kansas, with Downtown near the confluence of the Kansas and Missouri Rivers, the city encompasses about , making ...
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University Of Kansas
The University of Kansas (KU) is a public research university with its main campus in Lawrence, Kansas, United States, and several satellite campuses, research and educational centers, medical centers, and classes across the state of Kansas. Two branch campuses are in the Kansas City metropolitan area on the Kansas side: the university's medical school and hospital in Kansas City, Kansas, the Edwards Campus in Overland Park. There are also educational and research sites in Garden City, Hays, Leavenworth, Parsons, and Topeka, an agricultural education center in rural north Douglas County, and branches of the medical school in Salina and Wichita. The university is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". Founded March 21, 1865, the university was opened in 1866, under a charter granted by the Kansas State Legislature in 1864 and legislation passed in 1863 under the State Cons ...
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Duke University Faculty
Duke is a male title either of a monarch ruling over a duchy, or of a member of royalty, or nobility. As rulers, dukes are ranked below emperors, kings, grand princes, grand dukes, and sovereign princes. As royalty or nobility, they are ranked below princess nobility and grand dukes. The title comes from French ''duc'', itself from the Latin ''dux'', 'leader', a term used in republican Rome to refer to a military commander without an official rank (particularly one of Germanic or Celtic origin), and later coming to mean the leading military commander of a province. In most countries, the word ''duchess'' is the female equivalent. Following the reforms of the emperor Diocletian (which separated the civilian and military administrations of the Roman provinces), a ''dux'' became the military commander in each province. The title ''dux'', Hellenised to ''doux'', survived in the Eastern Roman Empire where it continued in several contexts, signifying a rank equivalent to a captain ...
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University Of Kansas Alumni
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university i ...
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Society For Glycobiology
A society is a group of individuals involved in persistent social interaction, or a large social group sharing the same spatial or social territory, typically subject to the same political authority and dominant cultural expectations. Societies are characterized by patterns of relationships (social relations) between individuals who share a distinctive culture and institutions; a given society may be described as the sum total of such relationships among its constituent of members. In the social sciences, a larger society often exhibits stratification or dominance patterns in subgroups. Societies construct patterns of behavior by deeming certain actions or concepts as acceptable or unacceptable. These patterns of behavior within a given society are known as societal norms. Societies, and their norms, undergo gradual and perpetual changes. Insofar as it is collaborative, a society can enable its members to benefit in ways that would otherwise be difficult on an individual b ...
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William C
William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the given name ''Wilhelm'' (cf. Proto-Germanic ᚹᛁᛚᛃᚨᚺᛖᛚᛗᚨᛉ, ''*Wiljahelmaz'' > German ''Wilhelm'' and Old Norse ᚢᛁᛚᛋᛅᚼᛅᛚᛘᛅᛋ, ''Vilhjálmr''). By regular sound changes, the native, inherited English form of th ...
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Lactose Synthetase
Lactose synthase is an enzyme that generates lactose from glucose and UDP-galactose. It is classified under . It consists of N-acetyllactosamine synthase and alpha-lactalbumin. Alpha-lactalbumin, which is expressed in response to prolactin, increases the affinity of N-acetyllactosamine synthase for its substrate, causing increased production of lactose during lactation. N-acetyllactosamine synthase N-acetyllactosamine synthase is a galactosyltransferase enzyme. It is a component of lactose synthase This enzyme modifies the connection between two molecule UDP-galactose and N-Acetyl-D-Glucosamine, N-actyl-D-glucosamine and generates two differe ... falls under the category of beta-1,4-galactosyltransferase, a type-II membrane protein found in the Golgi. Alpha-lactalbumin is a Ca2+ binding protein specific to mammary glands. Beta-1,4-galactosyltransferase consists of the catalytic component and alpha-lactalbumin consists of the regulatory component of lactose synthase. Alpha- ...
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Immunoglobulin
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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Hemoglobin
Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocytes) of almost all vertebrates (the exception being the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in blood carries oxygen from the respiratory organs (''e.g.'' lungs or gills) to the rest of the body (''i.e.'' tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power functions of an organism in the process called metabolism. A healthy individual human has 12to 20grams of hemoglobin in every 100mL of blood. In mammals, the chromoprotein makes up about 96% of the red blood cells' dry content (by weight), and around 35% of the total content (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL O2 per gram, which increases the total blood oxygen ...
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American Society For Biochemistry And Molecular Biology
The American Society for Biochemistry and Molecular Biology (ASBMB) is a learned society that was founded on December 26, 1906, at a meeting organized by John Jacob Abel (Johns Hopkins University). The roots of the society were in the American Physiological Society, which had been formed some 20 years earlier. ASBMB is the US member of the International Union of Biochemistry and Molecular Biology. The ASBMB was originally called the American Society of Biological Chemists, before obtaining its current name in 1987. The society is based in Rockville, Maryland. ASBMB's mission is to advance the science of biochemistry and molecular biology through publication of scientific and educational journals, the organization of scientific meetings, advocacy for funding of basic research and education, support of science education at all levels, and by promoting the diversity of individuals entering the scientific workforce. The organization currently has over 12,000 members. Publications Th ...
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Scientific Society
A learned society (; also learned academy, scholarly society, or academic association) is an organization that exists to promote an academic discipline, profession, or a group of related disciplines such as the arts and science. Membership may be open to all, may require possession of some qualification, or may be an honour conferred by election. Most learned societies are non-profit organizations, and many are professional associations. Their activities typically include holding regular conferences for the presentation and discussion of new research results and publishing or sponsoring academic journals in their discipline. Some also act as professional bodies, regulating the activities of their members in the public interest or the collective interest of the membership. History Some of the oldest learned societies are the Académie des Jeux floraux (founded 1323), the Sodalitas Litterarum Vistulana (founded 1488), the Accademia della Crusca (founded 1583), the Accademia de ...
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Philip Handler
Philip Handler (August 13, 1917 – December 29, 1981) was an American nutritionist, and biochemist. He was President of the United States National Academy of Sciences for two terms from 1969 to 1981. He was also a recipient of the National Medal of Science. Biography Handler grew up in a Jewish family in New York City. He received his B.S. degree from the City College of New York in 1936 and his Ph.D. from University of Illinois in 1939. He taught at Duke University where he was named the youngest chairman of the Department of Biochemistry, at 35. Handler remained at Duke until 1969, when he accepted the position of president of the National Academy of Sciences. As a biochemist, he published more than 200 papers on nutrition and metabolic activity. He was elected to the National Academy of Sciences in 1964. He received the National Medal of Science in 1981 for "his outstanding contribution to biochemical research, resulting in significant contributions to mankind, including re ...
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