Robert B. Mellor
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Robert B. Mellor
Robert B. Mellor (born in Yorkshire, UK) is a British scientist probably best known for his 1989 "unified vacuole theory", although also made significant contributions to environmental technology and to our understanding of the workings of the tech entrepreneurship ecosystem. Unified vacuole theory The theory states that in plant endosymbioses, the micro-symbiont and the macro-symbiont generally share their lytic vacuolar compartments. This stems from Mellor's earlier 1988 symbiosome (or "symbiosome is a lysosome") theory, which states that the organelle that microsymbionts inhabit partially takes over the lysosomal functions in these plant cells. These plant cells are analogous to the role of protein bodies in seeds, in particular that the rhizobial symbiosome is an organ-specific form of lysosome or vacuole in legume root nodules. The Marburg and Basel Years (plant biology) Mellor was interested in how plants distinguish between symbiotic and pathogenic infections. In ...
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London
London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a major settlement for two millennia. The City of London, its ancient core and financial centre, was founded by the Romans as '' Londinium'' and retains its medieval boundaries.See also: Independent city § National capitals The City of Westminster, to the west of the City of London, has for centuries hosted the national government and parliament. Since the 19th century, the name "London" has also referred to the metropolis around this core, historically split between the counties of Middlesex, Essex, Surrey, Kent, and Hertfordshire, which largely comprises Greater London, governed by the Greater London Authority.The Greater London Authority consists of the Mayor of London and the London Assembly. The London Mayor is distinguished fr ...
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Chitinase
Chitinases (EC 3.2.1.14, chitodextrinase, 1,4-β-poly-N-acetylglucosaminidase, poly-β-glucosaminidase, β-1,4-poly-N-acetyl glucosamidinase, poly ,4-(N-acetyl-β-D-glucosaminide)glycanohydrolase, (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase; systematic name (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin. They catalyse the following reaction: : Random endo-hydrolysis of ''N''-acetyl-β-D-glucosaminide (1→4)-β-linkages in chitin and chitodextrins As chitin is a component of the cell walls of fungi and exoskeletal elements of some animals (including mollusks and arthropods), chitinases are generally found in organisms that either need to reshape their own chitin or dissolve and digest the chitin of fungi or animals. Species distribution Chitinivorous organisms include many bacteria ( Aeromonads, ''Bacillus'', ''Vibrio'', among others), which may be pathogenic or detritivorous. The ...
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Regional Development
Regional development is a broad term but can be seen as a general effort to reduce regional disparities by supporting (employ) economin regions. In the past, regional development policy tended to try to achieve these objectives by means development and by attracting inward investment (OECD,2020). A large number of international organizations such as the OECD, UN, IMF and many more that provide assistance on economic, environmental and social issues to the less economically developed regions. Regional development can be national or international in nature. Therefore, the implications and scope of regional development may vary according to the definition of a region and how the region and its boundaries are perceived internally and externally. By country Canada * Atlantic Canada Opportunities Agency * Economic Development Agency of Canada for the Regions of Quebec * Federal Economic Development Initiative for Northern Ontario * Western Economic Diversification Canada Malaysia * ...
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Science Park
A science park (also called a "university research park", "technology park”, "technopark", “technopole", or a "science and technology park" (STP)) is defined as being a property-based development that accommodates and fosters the growth of tenant firms and that is affiliated with a university (or a government and private research bodies) based on proximity, ownership, and/or governance. This is so that knowledge can be shared, innovation promoted, technology transferred, and research outcomes progressed to viable commercial products. Science parks are also often perceived as contributing to national economic development, stimulating the formation of new high-technology firms, attracting foreign investment and promoting exports. Background The world's first university research park, Stanford Research Park was launched in 1951 as a cooperative venture between Stanford University and the City of Palo Alto. Another early university research park was Research Triangle Pa ...
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Big Data
Though used sometimes loosely partly because of a lack of formal definition, the interpretation that seems to best describe Big data is the one associated with large body of information that we could not comprehend when used only in smaller amounts. In it primary definition though, Big data refers to data sets that are too large or complex to be dealt with by traditional data-processing application software. Data with many fields (rows) offer greater statistical power, while data with higher complexity (more attributes or columns) may lead to a higher false discovery rate. Big data analysis challenges include capturing data, data storage, data analysis, search, sharing, transfer, visualization, querying, updating, information privacy, and data source. Big data was originally associated with three key concepts: ''volume'', ''variety'', and ''velocity''. The analysis of big data presents challenges in sampling, and thus previously allowing for only observations and sampling. ...
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Small And Medium-sized Enterprises
Small and medium-sized enterprises (SMEs) or small and medium-sized businesses (SMBs) are businesses whose personnel and revenue numbers fall below certain limits. The abbreviation "SME" is used by international organizations such as the World Bank, the European Union, the United Nations, and the World Trade Organization (WTO). In any given national economy, SMEs sometimes outnumber large companies by a wide margin and also employ many more people. For example, Australian SMEs makeup 98% of all Australian businesses, produce one-third of the total GDP (gross domestic product) and employ 4.7 million people. In Chile, in the commercial year 2014, 98.5% of the firms were classified as SMEs. In Tunisia, the self-employed workers alone account for about 28% of the total non-farm employment, and firms with fewer than 100 employees account for about 62% of total employment. The United States' SMEs generate half of all U.S. jobs, but only 40% of GDP. Developing countries tend to have a lar ...
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Stiglitz
Joseph Eugene Stiglitz (; born February 9, 1943) is an American New Keynesian economist, a public policy analyst, and a full professor at Columbia University. He is a recipient of the Nobel Memorial Prize in Economic Sciences (2001) and the John Bates Clark Medal (1979). He is a former senior vice president and chief economist of the World Bank. He is also a former member and chairman of the (US president's) Council of Economic Advisers. He is known for his support of Georgist public finance theory and for his critical view of the management of globalization, of ''laissez-faire'' economists (whom he calls " free-market fundamentalists"), and of international institutions such as the International Monetary Fund and the World Bank. In 2000, Stiglitz founded the Initiative for Policy Dialogue (IPD), a think tank on international development based at Columbia University. He has been a member of the Columbia faculty since 2001, and received the university's highest academic rank ( ...
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Mads Tofte
Mads Tofte (born 20 April 1959) is a Danish computer scientist who has contributed in particular to functional programming and the Standard ML programming language. Education Tofte was born in Lyngby, Denmark and grew up in Holbæk, Denmark. He studied computer science and mathematics at the University of Copenhagen where he obtained an MSc degree (with supervisor Neil D. Jones) in 1984; then at University of Edinburgh where he obtained a PhD degree in 1988 (advised by Robin Milner). He is doctor honoris causa 2007 from Kingston University. Research and career In his 1984 MSc thesis and prior work he investigated and formalized the CERES compiler generator (with Neil D. Jones), and showed that (1) a compiler generator is itself a compiler from language definitions to compilers; and (2) under suitable assumptions there exists a language definition that, when applied to itself, generates a compiler generator. This has close connections to self-application in partial evaluat ...
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Startup Company
A startup or start-up is a company or project undertaken by an entrepreneur to seek, develop, and validate a scalable business model. While entrepreneurship refers to all new businesses, including self-employment and businesses that never intend to become registered, startups refer to new businesses that intend to grow large beyond the solo founder. At the beginning, startups face high uncertainty and have high rates of failure, but a minority of them do go on to be successful and influential.Erin Griffith (2014)Why startups fail, according to their founders Fortune.com, 25 September 2014; accessed 27 October 2017 Actions Startups typically begin by a founder (solo-founder) or co-founders who have a way to solve a problem. The founder of a startup will begin market validation by problem interview, solution interview, and building a minimum viable product (MVP), i.e. a prototype, to develop and validate their business models. The startup process can take a long period of time (by so ...
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Electric Power
Electric power is the rate at which electrical energy is transferred by an electric circuit. The SI unit of power is the watt, one joule per second. Standard prefixes apply to watts as with other SI units: thousands, millions and billions of watts are called kilowatts, megawatts and gigawatts respectively. A common misconception is that electric power is bought and sold, but actually electrical energy is bought and sold. For example, electricity is sold to consumers in kilowatt-hours (kilowatts multiplied by hours), because energy is power multiplied by time. Electric power is usually produced by electric generators, but can also be supplied by sources such as electric batteries. It is usually supplied to businesses and homes (as domestic mains electricity) by the electric power industry through an electrical grid. Electric power can be delivered over long distances by transmission lines and used for applications such as motion, light or heat with high efficiency. ...
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Applied Science
Applied science is the use of the scientific method and knowledge obtained via conclusions from the method to attain practical goals. It includes a broad range of disciplines such as engineering and medicine. Applied science is often contrasted with basic science, which is focused on advancing scientific theories and laws that explain and predict events in the natural world. Applied science can also apply formal science, such as statistics and probability theory, as in epidemiology. Genetic epidemiology is an applied science applying both biological and statistical methods. Applied research Applied research is the practical application of science. It accesses and uses accumulated theories, knowledge, methods, and techniques, for a specific state-, business-, or client-driven purpose. Applied Research can be better understood in any area when contrasting it with, basic, or pure, research. Basic geography research strives to create new theories and methods that aid in the expl ...
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Drought Tolerance
Drought tolerance is the ability to which a plant maintains its biomass production during arid or drought conditions. Some plants are naturally adapted to dry conditions'','' surviving with protection mechanisms such as desiccation tolerance, detoxification, or repair of xylem embolism. Other plants, specifically crops like corn, wheat, and rice, have become increasingly tolerant to drought with new varieties created via genetic engineering. The plants behind drought tolerance are complex and involve many pathways which allows plants to respond to specific sets of conditions at any given time. Some of these interactions include stomatal conductance, carotenoid degradation and anthocyanin accumulation, the intervention of osmoprotectants (such as sucrose, glycine, and proline), ROS-scavenging enzymes. The molecular control of drought tolerance is also very complex and is influenced other factors such as environment and the developmental stage of the plant. This control consists ma ...
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