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Rhabdastrella Globostellata
''Rhabdastrella globostellata'', also known as the yellow pot sponge, is a marine sponge of the order Astrophorida. It is native to many regions of the Indian Ocean including the shores of Madagascar, the Seychelles, and Australia as well as the Malayan Peninsula and Singapore. It was first described by Henry J. Carter as ''Stelleta globostellata'' in 1883, named after the ''globostellate'' shape of its spicules (Latin ''globus'' meaning "sphere" and ''stellātus'' meaning "star-shaped"). ''R. globostellata'' has been shown to produce a wide variety of isomalabaricanes, a type of triterpene molecules with notable cytotoxic Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (''Bitis arietans'') or brown recluse spider (''Loxosceles reclusa''). Cell physiology Treating cells ... activity towards certain cancer cell lines. Further reading * References Tetractinellida Animals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henry John Carter
Henry John Carter, FRS (18 August 1813 – 4 May 1895) was a surgeon working in Bombay, India, who carried out work in geology, paleontology, and zoology. He worked as an army surgeon in Bombay from 1859 on Her Majesty's Indian Service, Bombay Establishment. He edited a collection of geological papers on Western India, including a summary of the geology of India, which was published in 1857. Many items of his published work appeared in the journal of the Bombay Branch of the Royal Asiatic Society, and in the Annals of Natural History. He was elected a Fellow of the Royal Society in 1859. Life and work Carter joined the Devon and Exeter Hospital at the age of sixteen, and graduated from University College in 1837 and obtained admission to the College of Surgeons in 1838. He was house surgeon for a year and then conservator of the museum. He visited Ecole de Medecine in Paris in 1840 and joined the East India Company in 1841. He served in Calcutta, Madras and Mauritius. He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Latin
Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the Roman Republic it became the dominant language in the Italian region and subsequently throughout the Roman Empire. Even after the fall of Western Rome, Latin remained the common language of international communication, science, scholarship and academia in Europe until well into the 18th century, when other regional vernaculars (including its own descendants, the Romance languages) supplanted it in common academic and political usage, and it eventually became a dead language in the modern linguistic definition. Latin is a highly inflected language, with three distinct genders (masculine, feminine, and neuter), six or seven noun cases (nominative, accusative, genitive, dative, ablative, and vocative), five declensions, four verb conjuga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetractinellida
Tetractinellida is an order of sea sponges belonging to the Class Demospongiae. First described in 1876, this order received a new description in 2012 and replaced the two orders Astrophorida and Spirophorida, which then became sub-orders as Astrophorina and Spirophorina. Families ; Suborder Astrophorina Sollas, 1887 * Family Ancorinidae Schmidt, 1870 * Family Calthropellidae Lendenfeld, 1907 * Family Corallistidae Sollas, 1888 * Family Geodiidae Gray, 1867 * Family Isoraphiniidae Schrammen, 1924 * Family Macandrewiidae Schrammen, 1924 * Family Neopeltidae Sollas, 1888 * Family Pachastrellidae Carter, 1875 * Family Phymaraphiniidae Schrammen, 1924 * Family Phymatellidae Schrammen, 1910 * Family Pleromidae Sollas, 1888 * Family Theneidae Carter, 1883 * Family Theonellidae Lendenfeld, 1903 * Family Thrombidae Sollas, 1888 * Family Vulcanellidae Vulcanellidae is a family of sponges belonging to the order Tetractinellida Tetractinellida is an Order (biology), order of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Singapore Science Centre
The Science Centre Singapore, previously known as Singapore Science Centre is a scientific institution in Jurong East, Singapore, specialising in the promotion of scientific and technological education for the general public. It houses over 850 exhibits over eight exhibition galleries and receives over a million visitors every year. In 2003, it celebrated its silver jubilee. History The Science Centre was carved out of the National Museum of Singapore as a separate institution so that the latter could focus on its artistic and historical collections. This idea was first mooted in 1969 by the former Science Council of Singapore, now known as the Agency for Science, Technology and Research (A*Star), and was approved by the government. The SCS building's design was decided by an architectural competition organised by the Science Centre Board, in which Raymond Woo architects' entry was selected. Built at a cost of S$12 million on a site in Jurong East, it was officially opene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Natural Products
The ''Journal of Natural Products'' is a monthly peer-reviewed scientific journal covering all aspects of research on the chemistry and/or biochemistry of naturally occurring compounds. It is co-published by the American Society of Pharmacognosy and the American Chemical Society. The editor-in-chief is Philip J. Proteau (Oregon State University). History The journal was established in 1938 as ''Lloydia'', published by the Lloyd Library and Museum, and obtained its present title in 1979. It has been the official journal of the American Society of Pharmacognosy since 1961. Originally a quarterly publication, it became a bimonthly journal in 1975, and has appeared monthly since 1992. The American Society of Pharmacognosy began to co-publish the journal with the American Chemical Society in 1996. In 2008, the journal was hijacked by a low-quality open access journal using the same title. , this counterfeit journal was still active. Abstracting and indexing The journal is abstracted a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions the need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases ( CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytotoxicity
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (''Bitis arietans'') or brown recluse spider (''Loxosceles reclusa''). Cell physiology Treating cells with the cytotoxic compound can result in a variety of cell fates. The cells may undergo necrosis, in which they lose membrane integrity and die rapidly as a result of cell lysis. The cells can stop actively growing and dividing (a decrease in cell viability), or the cells can activate a genetic program of controlled cell death (apoptosis). Cells undergoing necrosis typically exhibit rapid swelling, lose membrane integrity, shut down metabolism, and release their contents into the environment. Cells that undergo rapid necrosis in vitro do not have sufficient time or energy to activate apoptotic machinery and will not express apoptotic markers. Apoptosis is characterized by well defined cytological and molecular events including a change i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triterpene
Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squalene, the precursor to all steroids. Structures Triterpenes exist in a great variety of structures. Nearly 200 different skeletons have been identified. These skeletons may be broadly divided according to the number of rings present. In general pentacyclic structures (5 rings) tend to dominate. Squalene is biosynthesized through the head-to-head condensation of two farnesyl pyrophosphate units. This coupling converts a pair of C15 components into a C30 product. Squalene serves as precursor for the formation of many triterpenoids, including bacterial hopanoids and eukaryotic sterols. Triterpenoids By definition triterpenoids are triterpenes that possess heteroatoms, usually oxygen. The terms ''triterpene'' and ''triterpenoid'' oft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isomalabaricane
The molecule malabaricane and its derivatives, the malabaricanes, are triterpene and triterpenoid compounds found in various organisms. They are named after the rain forest tree ''Ailanthus malabarica'' (''Ailanthus triphysa''), from which they were first isolated in 1967 by scientists at the National Chemical Laboratory in Pune, India. Later, great varieties of malabaricanes were discovered in other organisms, mostly in marine sponges such as ''Rhabdastrella globostellata''. Isomalabaricanes are malabaricanes in which the three carbon rings of the molecule are connected in '' trans−syn−trans'' conformation, as opposed to other malabaricanes, where the rings are connected in ''trans−anti−trans'' conformation. They are of particular research interest because many of them have been reported to show anti-tumour activity in cell culture Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their nat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sponge Spicule
Spicules are structural elements found in most sponges. The meshing of many spicules serves as the sponge's skeleton and thus it provides structural support and potentially defense against predators. Sponge spicules are made of calcium carbonate or silica. Large spicules visible to the naked eye are referred to as megascleres, while smaller, microscopic ones are termed microscleres. The composition, size, and shape of spicules are major characters in sponge systematics and taxonomy. Overview Sponges are a species-rich clade of the earliest-diverging (most basal) animals. They are distributed globally, with diverse ecologies and functions, and a record spanning at least the entire Phanerozoic. Most sponges produce skeletons formed by spicules, structural elements that develop in a wide variety of sizes and three dimensional shapes. Among the four sub-clades of Porifera, three (Demospongiae, Hexactinellida, and Homoscleromorpha) produce skeletons of amorphous silica and on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Annals And Magazine Of Natural History
The ''Journal of Natural History'' is a scientific journal published by Taylor & Francis focusing on entomology and zoology. The journal was established in 1841 under the name ''Annals and Magazine of Natural History'' (''Ann. Mag. Nat. Hist.'') and obtained its current title in 1967. The journal was formed by the merger of the ''Magazine of Natural History'' (1828–1840) and the ''Annals of Natural History'' (1838–1840; previously the ''Magazine of Zoology and Botany'', 1836–1838) and '' Loudon and Charlesworth's Magazine of Natural History''. In September 1855, the ''Annals and Magazine of Natural History'' published "On the Law which has Regulated the Introduction of New Species", a paper which Alfred Russel Wallace had written while working in the state of Sarawak on the island of Borneo in February of that year. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Singapore
Singapore (), officially the Republic of Singapore, is a sovereign island country and city-state in maritime Southeast Asia. It lies about one degree of latitude () north of the equator, off the southern tip of the Malay Peninsula, bordering the Strait of Malacca to the west, the Singapore Strait to the south, the South China Sea to the east, and the Straits of Johor to the north. The country's territory is composed of one main island, 63 satellite islands and islets, and one outlying islet; the combined area of these has increased by 25% since the country's independence as a result of extensive land reclamation projects. It has the third highest population density in the world. With a multicultural population and recognising the need to respect cultural identities of the major ethnic groups within the nation, Singapore has four official languages: English, Malay, Mandarin, and Tamil. English is the lingua franca and numerous public services are available only in Eng ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
