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Retronecine
Retronecine is a pyrrolizidine alkaloid found in a variety of plants in the genera ''Senecio'' and ''Crotalaria'', and the family Boraginaceae Boraginaceae, the borage or forget-me-not family, includes about 2,000 species of shrubs, trees and herbs in 146, to 156 genera with a worldwide distribution. The APG IV system from 2016 classifies the Boraginaceae as single family of the order .... It is the most common central core for other pyrrolizidine alkaloids. References Pyrrolizidine alkaloids {{alkaloid-stub ...
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Pyrrolizidine Alkaloid
Pyrrolizidine alkaloids (PAs), sometimes referred to as necine bases, are a group of naturally occurring alkaloids based on the structure of pyrrolizidine. Pyrrolizidine alkaloids are produced by plants as a defense mechanism against insect herbivores. More than 660 PAs and PA N-oxides have been identified in over 6,000 plants, and about half of them exhibit hepatotoxicity. They are found frequently in plants in the Boraginaceae, Asteraceae, Orchidaceae and Fabaceae families; less frequently in the Convolvulaceae and Poaceae, and in at least one species in the Lamiaceae. It has been estimated that 3% of the world’s flowering plants contain pyrrolizidine alkaloids. Honey can contain pyrrolizidine alkaloids, as can grains, milk, offal and eggs. To date (2011), there is no international regulation of PAs in food, unlike those for herbs and medicines. Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disea ...
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Merck Index
''The Merck Index'' is an encyclopedia of chemical substance, chemicals, pharmaceutical drug, drugs and biomolecule, biologicals with over 10,000 monographs, monograph on single substances or groups of related chemical compound, compounds published online by the Royal Society of Chemistry. History The first edition of the Merck's Index was published in 1889 by the German chemical company Merck Group, Emanuel Merck and was primarily used as a sales catalog for Merck's growing list of chemicals it sold. The American subsidiary was established two years later and continued to publish it. During World War I the US government seized Merck's US operations and made it a separate American "Merck" company that continued to publish the Merck Index. In 2012 the Merck Index was licensed to the Royal Society of Chemistry. An online version of The Merck Index, including historic records and new updates not in the print edition, is commonly available through research libraries. It also include ...
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Intravenous Therapy
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth. It may also be used to administer medications or other medical therapy such as blood products or electrolytes to correct electrolyte imbalances. Attempts at providing intravenous therapy have been recorded as early as the 1400s, but the practice did not become widespread until the 1900s after the development of techniques for safe, effective use. The intravenous route is the fastest way to deliver medications and fluid replacement throughout the body as they are introduced directly into the circulatory system and thus quickly distributed. For this reason, the intravenous route of administration is also used for the consump ...
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Senecio
''Senecio'' is a genus of flowering plants in the daisy family (Asteraceae) that includes ragworts and groundsels. Variously circumscribed taxonomically, the genus ''Senecio'' is one of the largest genera of flowering plants. Description Morphology The flower heads are normally rayed with the heads borne in branched clusters, and usually completely yellow, but green, purple, white and blue flowers are known as well. In its current circumscription, the genus contains species that are annual or perennial herbs, shrubs, small trees, aquatics or climbers. The only species which are trees are the species formerly belonging to '' Robinsonia'' occurring on the Juan Fernández Islands. Chemistry Pyrrolizidine alkaloids are found in all ''Senecio'' species. These alkaloids serve as a natural biocides to deter or even kill animals that would eat them. Livestock generally do not find them palatable. ''Senecio'' species are used as food plants by the larvae of some Lepidoptera species t ...
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Crotalaria
''Crotalaria'' is a genus of flowering plants in the family Fabaceae (subfamily Faboideae) commonly known as rattlepods. The genus includes over 700 species of herbaceous plants and shrubs. Africa is the continent with the majority of ''Crotalaria'' species (approximately 400 species), which are mainly found in damp grassland, especially in floodplains, depressions and along edges of swamps and rivers, but also in deciduous bush land, roadsides and fields. Some species of ''Crotalaria'' are grown as ornamentals. The common name rattlepod or rattlebox is derived from the fact that the seeds become loose in the pod as they mature, and rattle when the pod is shaken. The name derives from the Ancient Greek , meaning " castanet", and is the same root as the name for the rattlesnakes (''Crotalus''). ''Crotalaria'' species are used as food plants by the larvae of some Lepidoptera species including ''Endoclita sericeus'', ''Etiella zinckenella'' and ''Utetheisa ornatrix''. The toxic al ...
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Boraginaceae
Boraginaceae, the borage or forget-me-not family, includes about 2,000 species of shrubs, trees and herbs in 146, to 156 genera with a worldwide distribution. The APG IV system from 2016 classifies the Boraginaceae as single family of the order Boraginales within the asterids. Under the older Cronquist system it was included in Lamiales, but it is now clear that it is no more similar to the other families in this order than they are to families in several other asterid orders. A revision of the Boraginales, also from 2016, split the Boraginaceae in eleven distinct families: Boraginaceae ''sensu stricto'', Codonaceae, Coldeniaceae, Cordiaceae, Ehretiaceae, Heliotropiaceae, Hoplestigmataceae, Hydrophyllaceae, Lennoaceae, Namaceae, and Wellstediaceae. These plants have alternately arranged leaves, or a combination of alternate and opposite leaves. The leaf blades usually have a narrow shape; many are linear or lance-shaped. They are smooth-edged or toothed, and some have petiol ...
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