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Redlich–Obersteiner's Zone
The Redlich–Obersteiner's zone, also known as the root entry zone, is a boundary between the central nervous system (CNS) and the peripheral nervous system (PNS).Redlich-Obersteiner zone
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The Redlich–Obersteiner's zone is located at the point of entry of either between cranial nerves and the brain or spinal nerves and the . This narrow zone is identified visually where there is a transition regarding myelin production. It is named after Emil Redlich and
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Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts. It is a structure composed of nervous tissue positioned along the rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain (precursor structures exist in onychophorans, gastropods and lancelets). The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal cord are both enclosed in the meninges. The meninges provide a barrier to chemicals dissolv ...
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Peripheral Nervous System
The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of nerves and ganglia, which lie outside the brain and the spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs, essentially serving as a relay between the brain and spinal cord and the rest of the body. Unlike the CNS, the PNS is not protected by the vertebral column and skull, or by the blood–brain barrier, which leaves it exposed to toxins. The peripheral nervous system can be divided into the somatic nervous system and the autonomic nervous system. In the somatic nervous system, the cranial nerves are part of the PNS with the exception of the optic nerve (cranial nerve II), along with the retina. The second cranial nerve is not a true peripheral nerve but a tract of the diencephalon. Cranial nerve ganglia, as with all ganglia, are part of the P ...
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Whonamedit?
''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliographies. The dictionary is hosted in Norway and maintained by medical historian Ole Daniel Enersen Ole Daniel Enersen (born March 14, 1943, in Oslo, Norway) is a Norwegian climber, photographer, journalist, writer, and medical historian. In 1965 he made the first ascent of the Trollveggen mountain in Romsdalen, Norway, along with Leif Normann .... References External links * Medical websites Medical dictionaries Eponyms {{online-dict-stub ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diameter of the spinal cord ranges from in the cervical and lumbar regions to in the thoracic area. The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the body, ...
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Emil Redlich
Emil Redlich (18 January 1866 – 9 June 1930) was an Austrian-JewishEdward Shorter, ''A Historical Dictionary of Psychiatry'', Oxford University Press (2005), p. 265 neurologist born in Brünn. In 1889 he received his doctorate from the University of Vienna, and later performed anatomical research of the brain at Heinrich Obersteiner’s institute. In 1895 he was a medical assistant at Julius Wagner-Jauregg's neurological institute, and in 1898 became head of a private mental institution in Inzersdorf, outside of Vienna. In 1914 he was appointed director of the ''Nervenheilanstalt Maria-Theresia-Schlössel'' in Vienna. His name is associated with Redlich–Obersteiner's zone; the anatomical location where the central nervous system meets the peripheral nervous system. He also described a type of abortive disseminated encephalomyelitis with lesions scattered throughout the spinal cord and brain. This disorder was to become known as "Redlich–Flatau syndrome", named along wit ...
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Heinrich Obersteiner
Heinrich Obersteiner (13 November 1847 – 19 November 1922) was an Austrian neurologist born in Vienna. In 1870 earned his doctorate from the University of Vienna, where he worked in the laboratory of Ernst Wilhelm von Brücke (1819–1892). In 1873 he earned his habilitation for pathology and anatomy of the nervous system at the University of Vienna, becoming an associate professor in 1880, and receiving the title of "full professor" in 1898. He was also director of a private mental institution at Oberdöbling, outside of Vienna. In 1882 he established an internationally known neurological institute in Vienna. The eponymous Obersteiner–Redlich line is named after him, along with Emil Redlich (1866–1930). This zone is where the central nervous system and peripheral nervous system meet, as well as the place where Schwann cells meet oligodendroglia cells. Written works * '' Anleitung beim Studium des baues der nervösen Centralorgane im gesunden und kranken Zustande''. L ...
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Schwann Cell
Schwann cells or neurolemmocytes (named after German physiologist Theodor Schwann) are the principal glia of the peripheral nervous system (PNS). Glial cells function to support neurons and in the PNS, also include satellite cells, olfactory ensheathing cells, enteric glia and glia that reside at sensory nerve endings, such as the Pacinian corpuscle. The two types of Schwann cells are myelinating and nonmyelinating. Myelinating Schwann cells wrap around axons of motor and sensory neurons to form the myelin sheath. The Schwann cell promoter is present in the downstream region of the human dystrophin gene that gives shortened transcript that are again synthesized in a tissue-specific manner. During the development of the PNS, the regulatory mechanisms of myelination are controlled by feedforward interaction of specific genes, influencing transcriptional cascades and shaping the morphology of the myelinated nerve fibers. Schwann cells are involved in many important aspects of peri ...
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Oligodendrocyte
Oligodendrocytes (), or oligodendroglia, are a type of neuroglia whose main functions are to provide support and insulation to axons in the central nervous system of jawed vertebrates, equivalent to the function performed by Schwann cells in the peripheral nervous system. Oligodendrocytes do this by creating the myelin sheath. A single oligodendrocyte can extend its processes to 50 axons, wrapping approximately 1 μm of myelin sheath around each axon; Schwann cells, on the other hand, can wrap around only one axon. Each oligodendrocyte forms one segment of myelin for several adjacent axons. Oligodendrocytes are found only in the central nervous system, which comprises the brain and spinal cord. These cells were originally thought to have been produced in the ventral neural tube; however, research now shows oligodendrocytes originate from the ventral ventricular zone of the embryonic spinal cord and possibly have some concentrations in the forebrain. They are the last cell ...
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