Ralf F. W. Bartenschlager
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Ralf F. W. Bartenschlager
Ralf F. W. Bartenschlager (born 29 May 1958) is a German virologist who has been researching hepatitis C since 1989. He is a professor in the Department of Infectious Diseases at the Heidelberg University. Early life Bartenschlager grew up in Mannheim. After high school, he worked as a policemen for four years before starting his undergraduate in biology in 1981 at Heidelberg University. He conduced his thesis work with Heinz Schaller at the ZMBH in Heidelberg on the structure and functional role of the P-protein in Hepatitis B viruses. After graduating in 1990, he continued working as a postdoc at Heidelberg University until joining Hoffmann-La Roche in 1991, where he began working on Hepatitis C. Other activities * Robert Koch Institute (RKI), Member of the Scientific Advisory Board * Wilhelm Sander Foundation, Member of the Scientific Advisory Board Recognition Bartenschlager was a recipient of the 2016 Lasker Award for Clinical Research for discoveries related to ...
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Mannheim
Mannheim (; Palatine German: or ), officially the University City of Mannheim (german: Universitätsstadt Mannheim), is the second-largest city in the German state of Baden-Württemberg after the state capital of Stuttgart, and Germany's 21st-largest city, with a 2020 population of 309,119 inhabitants. The city is the cultural and economic centre of the Rhine-Neckar Metropolitan Region, Germany's seventh-largest metropolitan region with nearly 2.4 million inhabitants and over 900,000 employees. Mannheim is located at the confluence of the Rhine and the Neckar in the Kurpfalz (Electoral Palatinate) region of northwestern Baden-Württemberg. The city lies in the Upper Rhine Plain, Germany's warmest region. Together with Hamburg, Mannheim is the only city bordering two other federal states. It forms a continuous conurbation of around 480,000 inhabitants with Ludwigshafen am Rhein in the neighbouring state of Rhineland-Palatinate, on the other side of the Rhine. Some northe ...
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University Of Heidelberg
} Heidelberg University, officially the Ruprecht Karl University of Heidelberg, (german: Ruprecht-Karls-Universität Heidelberg; la, Universitas Ruperto Carola Heidelbergensis) is a public research university in Heidelberg, Baden-Württemberg, Germany. Founded in 1386 on instruction of Pope Urban VI, Heidelberg is Germany's oldest university and one of the world's oldest surviving universities; it was the third university established in the Holy Roman Empire. Heidelberg is one of the most prestigious and highly ranked universities in Europe and the world. Heidelberg has been a coeducational institution since 1899. The university consists of twelve faculties and offers degree programmes at undergraduate, graduate and postdoctoral levels in some 100 disciplines. The language of instruction is usually German, while a considerable number of graduate degrees are offered in English as well as some in French. As of 2021, 57 Nobel Prize winners have been affiliated with the city o ...
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University Of Mainz
The Johannes Gutenberg University Mainz (german: Johannes Gutenberg-Universität Mainz) is a public research university in Mainz, Rhineland Palatinate, Germany, named after the printer Johannes Gutenberg since 1946. With approximately 32,000 students (2018) in about 100 schools and clinics, it is among the largest universities in Germany. Starting on 1 January 2005 the university was reorganized into 11 faculties of study. The university is a member of the German U15, a coalition of fifteen major research-intensive and leading medical universities in Germany. The Johannes Gutenberg University is considered one of the most prestigious universities in Germany. The university is part of the IT-Cluster Rhine-Main-Neckar. The Johannes Gutenberg University Mainz, the Goethe University Frankfurt and the Technische Universität Darmstadt together form the Rhine-Main-Universities (RMU). History The first University of Mainz goes back to the Archbishop of Mainz, Prince-elector and ...
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Hepatitis C
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, abdominal pain, and yellow tinged skin occurs. The virus persists in the liver in about 75% to 85% of those initially infected. Early on, chronic infection typically has no symptoms. Over many years however, it often leads to liver disease and occasionally cirrhosis. In some cases, those with cirrhosis will develop serious complications such as liver failure, liver cancer, or dilated blood vessels in the esophagus and stomach. HCV is spread primarily by blood-to-blood contact associated with injection drug use, poorly sterilized medical equipment, needlestick injuries in healthcare, and transfusions. Using blood screening, the risk from a transfusion is less than one per two million. It may also be spread from an infected mother to her ...
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Heidelberg University
} Heidelberg University, officially the Ruprecht Karl University of Heidelberg, (german: Ruprecht-Karls-Universität Heidelberg; la, Universitas Ruperto Carola Heidelbergensis) is a public research university in Heidelberg, Baden-Württemberg, Germany. Founded in 1386 on instruction of Pope Urban VI, Heidelberg is Germany's oldest university and one of the world's oldest surviving universities; it was the third university established in the Holy Roman Empire. Heidelberg is one of the most prestigious and highly ranked universities in Europe and the world. Heidelberg has been a coeducational institution since 1899. The university consists of twelve faculties and offers degree programmes at undergraduate, graduate and postdoctoral levels in some 100 disciplines. The language of instruction is usually German, while a considerable number of graduate degrees are offered in English as well as some in French. As of 2021, 57 Nobel Prize winners have been affiliated with the city o ...
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Hoffmann-La Roche
F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth largest pharmaceutical company in the world by revenue, and the leading provider of cancer treatments globally. The company controls the American biotechnology company Genentech, which is a wholly owned affiliate, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States-based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020 were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, and Maja Oeri a further 5% apart), with Swiss pharma firm Novartis owning a furth ...
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Robert Koch Institute
The Robert Koch Institute (RKI) is a German federal government agency and research institute responsible for disease control and prevention. It is located in Berlin and Wernigerode. As an upper federal agency, it is subordinate to the Federal Ministry of Health. It was founded in 1891 and is named for its founding director, the founder of modern bacteriology and Nobel laureate Robert Koch. Tasks The Robert Koch Institute monitors public health. Its core tasks include the detection, prevention and combatting of infectious diseases and non-communicable diseases in Germany. The institute advises the specialist public and government, e.g. on preventing and tackling infectious disease outbreaks such as the COVID-19 pandemic, the swine flu pandemic in 2009 and the EHEC O104:H4 outbreak in 2011. The institute is also in charge of health monitoring and health reporting in Germany, covering non-communicable diseases: in large monitoring studies, RKI monitors the health status of ad ...
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Lasker Award
The Lasker Awards have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine. They are administered by the Lasker Foundation, which was founded by Albert Lasker and his wife Mary Woodard Lasker (later a medical research activist). The awards are sometimes referred to as "America's Nobels". The Lasker Awards have gained a reputation for identifying future winners of the Nobel Prize. Eighty-six Lasker laureates have received the Nobel Prize, including 32 in the last two decades. Claire Pomeroy is the current president of the Lasker Foundation. Award The award is given in four branches of medical science: # Albert Lasker Basic Medical Research Award # Lasker-DeBakey Clinical Medical Research Award # Lasker-Bloomberg Public Service Award (Renamed in 2011 from Mary Woodard Lasker Public Service Award. Renamed in 2000 from Albert Lasker Public Service Award.) # ''Lasker-Koshl ...
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Hepatitis C Virus
The hepatitis C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family ''Flaviviridae''. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. Taxonomy The hepatitis C virus belongs to the genus ''Hepacivirus'', a member of the family ''Flaviviridae''. Before 2011, it was considered to be the only member of this genus. However a member of this genus has been discovered in dogs: canine hepacivirus. There is also at least one virus in this genus that infects horses. Several additional viruses in the genus have been described in bats and rodents. Structure The hepatitis C virus particle consists of a lipid membrane envelope that is 55 to 65 nm in diameter. Two viral envelope glycoproteins, E1 and E2, are embedded in the lipid envelope. They take part in viral attachment and entry into the cell. Within the envel ...
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Charles M
Charles is a masculine given name predominantly found in English and French speaking countries. It is from the French form ''Charles'' of the Proto-Germanic name (in runic alphabet) or ''*karilaz'' (in Latin alphabet), whose meaning was "free man". The Old English descendant of this word was '' Ċearl'' or ''Ċeorl'', as the name of King Cearl of Mercia, that disappeared after the Norman conquest of England. The name was notably borne by Charlemagne (Charles the Great), and was at the time Latinized as ''Karolus'' (as in ''Vita Karoli Magni''), later also as '' Carolus''. Some Germanic languages, for example Dutch and German, have retained the word in two separate senses. In the particular case of Dutch, ''Karel'' refers to the given name, whereas the noun ''kerel'' means "a bloke, fellow, man". Etymology The name's etymology is a Common Germanic noun ''*karilaz'' meaning "free man", which survives in English as churl (< Old English ''ċeorl''), which developed its dep ...
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Michael J
Michael may refer to: People * Michael (given name), a given name * Michael (surname), including a list of people with the surname Michael Given name "Michael" * Michael (archangel), ''first'' of God's archangels in the Jewish, Christian and Islamic religions * Michael (bishop elect), English 13th-century Bishop of Hereford elect * Michael (Khoroshy) (1885–1977), cleric of the Ukrainian Orthodox Church of Canada * Michael Donnellan (1915–1985), Irish-born London fashion designer, often referred to simply as "Michael" * Michael (footballer, born 1982), Brazilian footballer * Michael (footballer, born 1983), Brazilian footballer * Michael (footballer, born 1993), Brazilian footballer * Michael (footballer, born February 1996), Brazilian footballer * Michael (footballer, born March 1996), Brazilian footballer * Michael (footballer, born 1999), Brazilian footballer Rulers =Byzantine emperors= *Michael I Rangabe (d. 844), married the daughter of Emperor Nikephoros I * M ...
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Beijerinck Virology Prize
The M.W. Beijerinck Virology Prize (''M.W. Beijerinck Virologie Prijs'') is a prize in virology awarded every two years by the ''Koninklijke Nederlandse Akademie van Wetenschappen'' (KNAW). The prize consists of a medal and a monetary award of €35,000. KNAW's two conditions for the prize nomination are that the nominee must be an internationally recognized researcher who has "made a groundbreaking contribution to research in the field of virology in the broadest sense" and must have an appointment at a university or research institute. The prize is named in honor of the Dutch microbiologist Martinus Willem Beijerinck. KNAW appoints an advisory committee which gives advice to KNAW concerning the prize nominees. KNAW has regulations for who may submit nominations. Before 2014 the prize was awarded every three years. Prize winners *1966 Egbertus van Slogteren, Netherlands *1969 , United States *1972 W. Berends, Netherlands *1975 E.M.J. Jaspars and A. van Kammen, Netherlands * ...
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