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RZPD
The German Resource Center for Genome Research (RZPD, Resourcenzentrum Primärdatenbank) was a service center for gene and genome research in Berlin-Charlottenburg and Heidelberg. History In 1987 Hans Lehrach and Günther Zehetner founded the ''Reference Library / Primary Database (RLDB)'' at the Imperial Cancer Research Fund (ICRF) in London. The RLDB distributed macroarrays generated at the ICRF to research groups worldwide. The macroarrays consisted of clones of genomic and cDNA libraries transferred to 22 × 22 cm nylon filters with the help of robots which have been developed by Zehetner at the ICRF. The first-generation machines achieved a 1/100 mm resolution employing two-phase stepper motors in a half-step modus with 400 steps per rotation. These robots achieved spotting densities of more than 400 dots per square centimeter having been programmed for a spatial resolution of 0.015 mm over a moving length of 600 mm. A second generation of robots engineered from 1991 to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berlin-Charlottenburg
Charlottenburg () is a locality of Berlin within the borough of Charlottenburg-Wilmersdorf. Established as a town in 1705 and named after Sophia Charlotte of Hanover, Queen consort of Prussia, it is best known for Charlottenburg Palace, the largest surviving royal palace in Berlin, and the adjacent museums. Charlottenburg was an independent city to the west of Berlin until 1920 when it was incorporated into "Groß-Berlin" (Greater Berlin) and transformed into a borough. In the course of Berlin's 2001 administrative reform it was merged with the former borough of Wilmersdorf becoming a part of a new borough called Charlottenburg-Wilmersdorf. Later, in 2004, the new borough's districts were rearranged, dividing the former borough of Charlottenburg into the localities of Charlottenburg proper, Westend and Charlottenburg-Nord. Geography Charlottenburg is located in Berlin's inner city, west of the Großer Tiergarten park. Its historic core, the former village green of Alt Lietzow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRC Press
The CRC Press, LLC is an American publishing group that specializes in producing technical books. Many of their books relate to engineering, science and mathematics. Their scope also includes books on business, forensics and information technology. CRC Press is now a division of Taylor & Francis, itself a subsidiary of Informa. History The CRC Press was founded as the Chemical Rubber Company (CRC) in 1903 by brothers Arthur, Leo and Emanuel Friedman in Cleveland, Ohio, based on an earlier enterprise by Arthur, who had begun selling rubber laboratory aprons in 1900. The company gradually expanded to include sales of laboratory equipment to chemists. In 1913 the CRC offered a short (116-page) manual called the ''Rubber Handbook'' as an incentive for any purchase of a dozen aprons. Since then the ''Rubber Handbook'' has evolved into the CRC's flagship book, the ''CRC Handbook of Chemistry and Physics''. In 1964, Chemical Rubber decided to focus on its publishing ventures ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IMAGE CDNA Clones
IMAGE cDNA clones are a collection of DNA vectors containing cDNAs from various organisms including human, mouse, rat, non-human primates, zebrafish, pufferfish, Xenopus (frogs), and cow. Together they represent a more or less complete set of expressed genes from these organisms. IMAGE stands for ''integrated molecular analysis of genomes and their expression''. Curators From 1993 to 2007, the cDNA library was maintained by the ''IMAGE Consortium'', a joint effort of four academic groups led by Drs. Greg Lennon, Charles Auffray, Mihael Polymeropoulos, and Marcelo Bento Soares. At the end of 2007, the consortium handed over operations and stocks to a company associated with Open Biosystems. See also * complementary DNA (cDNA) * cDNA library * expressed sequence tags (EST) * vector (molecular biology) * cloning vector A cloning vector is a small piece of DNA that can be stably maintained in an organism, and into which a foreign DNA fragment can be inserted for cloning pu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Database
In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spans formal techniques and practical considerations, including data modeling, efficient data representation and storage, query languages, security and privacy of sensitive data, and distributed computing issues, including supporting concurrent access and fault tolerance. A database management system (DBMS) is the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS software additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an appli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Federal Ministry Of Education And Research (Germany)
The Federal Ministry of Education and Research (german: link=no, Bundesministerium für Bildung und Forschung, ), abbreviated BMBF, is a cabinet-level ministry of Germany. It is headquartered in Bonn, with an office in Berlin. The Ministry provides funding for research projects and institutions (aiming for "research excellence") and sets general educational policy. It also provides student loans in Germany. However, a large part of educational policy in Germany is decided at the state level, strongly limiting the influence of the ministry in educational matters. History The ''Federal Ministry for Atomic Issues'' was established in 1955, concentrating on research in the peaceful use of nuclear energy. The ministry was renamed in 1962 to ''Federal Ministry of Scientific Research'', with a broader scope; it was renamed again, to ''Federal Ministry of Education and Science'', in 1969. A separate ministry, the ''Federal Ministry of Research and Technology'', was established in 1972. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Cancer Research Center
The German Cancer Research Center (known as the Deutsches Krebsforschungszentrum or simply DKFZ in German) is a national cancer research center based in Heidelberg, Germany. It is a member of the Helmholtz Association of German Research Centres, the largest scientific organization in Germany. History The establishment of a national cancer research center in Germany was initiated by Heidelberg surgeon . The DKFZ was set up in 1964 by resolution of the State government of Baden-Württemberg as a foundation under public law. In 1975, the Center became a member of the Association of National Research Centers ("Arbeitsgemeinschaft der Großforschungseinrichtungen") which was transformed into the Hermann von Helmholtz Association of National Research Centers in 1995. The Center has also been a member of the Deutsche Forschungsgemeinschaft (DFG) since 1977. Two scientists to date that were affiliated with the DKFZ have received Nobel Prizes. The first was Harald zur Hausen H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berlin-Dahlem
Dahlem ( or ) is a locality of the Steglitz-Zehlendorf borough in southwestern Berlin. Until Berlin's 2001 administrative reform it was a part of the former borough of Zehlendorf. It is located between the mansion settlements of Grunewald and Lichterfelde West. Dahlem is one of the most affluent parts of the city and a center for academic research. It is home to the Freie Universität Berlin The Free University of Berlin (, often abbreviated as FU Berlin or simply FU) is a public research university in Berlin, Germany. It is consistently ranked among Germany's best universities, with particular strengths in political science and t ..., with its architecturally significant Philological Library ''("The Brain")''. Several other research institutions and museums, as well as parts of the Grunewald (forest), Grunewald forest with its Renaissance architecture, renaissance hunting lodge, are located in Dahlem. The U3 (Berlin U-Bahn), U3 line of the Berlin U-Bahn system connec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It remains the world's largest collaborative biological project. Planning started after the idea was picked up in 1984 by the US government, the project formally launched in 1990, and was declared essentially complete on April 14, 2003, but included only about 85% of the genome. Level "complete genome" was achieved in May 2021, with a remaining only 0.3% bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the United States government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Die Welt
''Die Welt'' ("The World") is a German national daily newspaper, published as a broadsheet by Axel Springer SE. ''Die Welt'' is the flagship newspaper of the Axel Springer publishing group. Its leading competitors are the ''Frankfurter Allgemeine Zeitung'', the ''Süddeutsche Zeitung'' and the ''Frankfurter Rundschau''. The modern paper takes a self-described "liberal Cosmopolitanism, cosmopolitan" position in editing, but it is generally considered to be conservative."The World from Berlin" ''Der Spiegel'', 28 December 2009."Divided on unification" ''The Economist'', 4 October 2010. As of 2016, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Planck Institute For Molecular Genetics
The Max Planck Institute for Molecular Genetics is a research institute for molecular genetics based in Berlin, Germany. It is part of the Max Planck Institute network of the Max Planck Society for the Advancement of Science. Departments and research groups * Department of Developmental Genetics (Bernhard Herrmann) *Department of Genome Regulation (Alexander Meissner) **Genome Regulation Group (Alexander Meissner) **Stem Cell Chromatin Group (Aydan Bulut-Karslioglu) **Lab for Human Brain & Neural Stem Cell Studies (Yechiel Elkabetz) **Precision Gene Control group (Denes Hnisz) **Cellular Phenotyping Group (Franz-Josef Müller) *Department of Computational Molecular Biology (Martin Vingron) **Transcriptional Regulation Group (Martin Vingron) **Mechanisms of Transcriptional Regulation Group (Sebastiaan H. Meijsing) **Chromatin Structure and Function Group (Sarah Kinkley) **Bioinformatics Group (Ralf Herwig) **Research Group Evolutionary Genomics (Peter Arndt) *Otto Warburg Laborato ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microtiter Plates
A microplate, also known as a microtiter plate (''Microtiter'' is a registered trademark in the United States, therefore it should not be used generically without attribution), microwell plate or multiwell, is a flat plate with multiple "wells" used as small test tubes. The microplate has become a standard tool in analytical research and clinical diagnostic testing laboratories. A very common usage is in the enzyme-linked immunosorbent assay (ELISA), the basis of most modern medical diagnostic testing in humans and animals. A microplate typically has 6, 12, 24, 48, 96, 384 or 1536 sample wells arranged in a 2:3 rectangular matrix. Some microplates have been manufactured with 3456 or 9600 wells, and an "array tape" product has been developed that provides a continuous strip of microplates embossed on a flexible plastic tape. Each well of a microplate typically holds somewhere between tens of nanolitres to several millilitres of liquid. They can also be used to store dry powder ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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