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R. R. Race
Robert Russell Race CBE FRS FRCP FRCPath MRCS (28 November 1907 – 15 April 1984) was a British medical doctor and human geneticist. He was Director of the Medical Research Council Blood Group Unit, of the Lister Institute of Preventive Medicine. His second wife, whom he married in 1956, was Ruth Sanger, who succeeded him in the post. Career In 1937, after training at St Bartholomew's Hospital in London, Race worked as a serologist in the blood-typing department being established by Ronald Fisher at the Galton Laboratory at University College London. The serum unit moved to Cambridge at the beginning of the Second World War, and in 1941 Race and Arthur Mourant began investigating the family of Rh antigens. This work followed from developments made by Karl Landsteiner and Alexander S. Wiener in the USA. In 1946 Race was appointed head of the Medical Research Council Blood Group Research Unit. During the same year, Ruth Sanger moved to London to complete her PhD. She ...
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Kingston Upon Hull
Kingston upon Hull, usually abbreviated to Hull, is a port city and unitary authority in the East Riding of Yorkshire, England. It lies upon the River Hull at its confluence with the Humber Estuary, inland from the North Sea and south-east of York, the historic county town. With a population of (), it is the fourth-largest city in the Yorkshire and the Humber region after Leeds, Sheffield and Bradford. The town of Wyke on Hull was founded late in the 12th century by the monks of Meaux Abbey as a port from which to export their wool. Renamed ''Kings-town upon Hull'' in 1299, Hull had been a market town, military supply port, trading centre, fishing and whaling centre and industrial metropolis. Hull was an early theatre of battle in the English Civil Wars. Its 18th-century Member of Parliament, William Wilberforce, took a prominent part in the abolition of the slave trade in Britain. More than 95% of the city was damaged or destroyed in the blitz and suffered a perio ...
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Ronald Fisher
Sir Ronald Aylmer Fisher (17 February 1890 – 29 July 1962) was a British polymath who was active as a mathematician, statistician, biologist, geneticist, and academic. For his work in statistics, he has been described as "a genius who almost single-handedly created the foundations for modern statistical science" and "the single most important figure in 20th century statistics". In genetics, his work used mathematics to combine Mendelian genetics and natural selection; this contributed to the revival of Darwinism in the early 20th-century revision of the theory of evolution known as the modern synthesis. For his contributions to biology, Fisher has been called "the greatest of Darwin’s successors". Fisher held strong views on race and eugenics, insisting on racial differences. Although he was clearly a eugenist and advocated for the legalization of voluntary sterilization of those with heritable mental disabilities, there is some debate as to whether Fisher supported sc ...
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1984 Deaths
Events January * January 1 – The Bornean Sultanate of Brunei gains full independence from the United Kingdom, having become a British protectorate in 1888. * January 7 – Brunei becomes the sixth member of the Association of Southeast Asian Nations (ASEAN). * January 10 ** The United States and the Vatican (Holy See) restore full diplomatic relations. ** The Victoria Agreement is signed, institutionalising the Indian Ocean Commission. *January 24 – Steve Jobs launches the Macintosh personal computer in the United States. February * February 3 ** Dr. John Buster and the research team at Harbor–UCLA Medical Center announce history's first embryo transfer from one woman to another, resulting in a live birth. ** STS-41-B: Space Shuttle ''Challenger'' is launched on the 10th Space Shuttle mission. * February 7 – Astronauts Bruce McCandless II and Robert L. Stewart make the first untethered space walk. * February 8– 19 – The 1984 Winter Olympics are held i ...
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1907 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ...
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Wellcome Library
The Wellcome Library is founded on the collection formed by Sir Henry Wellcome (1853–1936), whose personal wealth allowed him to create one of the most ambitious collections of the 20th century. Henry Wellcome's interest was the history of medicine in a broad sense and included subjects such as alchemy or witchcraft, but also anthropology and ethnography. Since Henry Wellcome's death in 1936, the Wellcome Trust has been responsible for maintaining the Library's collection and funding its acquisitions. The library is free and open to the public. History Henry Wellcome began collecting books seriously in the late 1890s, using a succession of agents and dealers, and by travelling around the world to gather whatever could be found. Wellcome's first major entry into the market took place at the auction of William Morris's library in 1898, where he was the biggest single purchaser, taking away about a third of the lots. His interests were truly international and the broad coverage of ...
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Gairdner Foundation International Award
The Canada Gairdner International Award is given annually by the Gairdner Foundation at a special dinner to five individuals for outstanding discoveries or contributions to medical science. Receipt of the Gairdner is traditionally considered a precursor to winning the Nobel Prize in Medicine; as of 2020, 95 Nobel Prizes have been awarded to prior Gairdner recipients. Canada Gairdner International Awards are given annually in the amount of $100,000 (each) payable in Canadian funds and can be awarded to residents of any country in the world. A joint award may be given for the same discovery or contribution to medical science, but in that case each awardee receives a full prize. Past winners *1959 Alfred Blalock, , Harry M. Rose, William D.M. Paton, Eleanor Zaimis, Wilfred G. Bigelow *1960 Joshua Harold Burn, John H. Gibbon Jr., William F. Hamilton, John McMichael, Karl Meyer, Arnold Rice Rich *1961 Russell Brock, Alan C. Burton, Alexander B. Gutman, Jonas H. Kellgren ...
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Karl Landsteiner Memorial Award
The Karl Landsteiner Memorial Award is a scientific award given by the American Association of Blood Banks (AABB) to scientists with "an international reputation in transfusion medicine or cellular therapies" "whose original research resulted in an important contribution to the body of scientific knowledge". Recipients give a lecture at the AABB Annual Meeting and receive a $7,500 honorarium. The prize was initiated in 1954 to honor Karl Landsteiner, whose research laid the foundation for modern blood transfusion therapy. Recipients * 1954 Reuben Ottenberg * 1955 Richard Lewisohn * 1956 Philip Levine, Alexander Solomon Wiener * 1957 Ruth Sanger, Robert Russell Race * 1958 Oswald Hope Robertson, Francis Peyton Rous, J. R. Turner * 1959 Ernest Witebsky * 1960 Patrick L. Mollison * 1961 Robert R. A. Coombs * 1962 William C. Boyd * 1963 Fred H. Allen Jr., Louis K. Diamond * 1964 J. J. van Loghem * 1965 Ruggero Ceppellini * 1966 Elvin A. Kabat * 1967 Walter Morgan, Winifred W ...
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X Chromosome
The X chromosome is one of the two sex-determining chromosomes (allosomes) in many organisms, including mammals (the other is the Y chromosome), and is found in both males and females. It is a part of the XY sex-determination system and XO sex-determination system. The X chromosome was named for its unique properties by early researchers, which resulted in the naming of its counterpart Y chromosome, for the next letter in the alphabet, following its subsequent discovery. Discovery It was first noted that the X chromosome was special in 1890 by Hermann Henking in Leipzig. Henking was studying the testicles of ''Pyrrhocoris'' and noticed that one chromosome did not take part in meiosis. Chromosomes are so named because of their ability to take up staining (''chroma'' in Greek means ''color''). Although the X chromosome could be stained just as well as the others, Henking was unsure whether it was a different class of object and consequently named it ''X element'', which later be ...
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Xg Antigen System
The XG antigen is a red blood cell surface antigen discovered in 1962. by researchers at the MRC Blood Group Unit.Mann, J. D., Cahan, A., Gelb, A. G., Fisher, N., Hamper, J., Tippett, P., Sanger, R., Race, R. R A sex-linked blood group. Lancet. 1962;279:8. The PBDX gene that encodes the antigen is located on the short arm of the X chromosome. Since males normally have one X chromosome they are considered hemizygotes. Since women have two copies of the gene and could be heterozygotic for the presence or absence of the functioning gene they could (through the process of lyonisation) express the functioning protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ... on just some of their red blood cells. Frequency References Blood antigen systems {{cell-biology-stub Transf ...
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Alexander S
Alexander is a male given name. The most prominent bearer of the name is Alexander the Great, the king of the Ancient Greek kingdom of Macedonia who created one of the largest empires in ancient history. Variants listed here are Aleksandar, Aleksander and Aleksandr. Related names and diminutives include Iskandar, Alec, Alek, Alex, Alexandre, Aleks, Aleksa and Sander; feminine forms include Alexandra, Alexandria, and Sasha. Etymology The name ''Alexander'' originates from the (; 'defending men' or 'protector of men'). It is a compound of the verb (; 'to ward off, avert, defend') and the noun (, genitive: , ; meaning 'man'). It is an example of the widespread motif of Greek names expressing "battle-prowess", in this case the ability to withstand or push back an enemy battle line. The earliest attested form of the name, is the Mycenaean Greek feminine anthroponym , , (/ Alexandra/), written in the Linear B syllabic script. Alaksandu, alternatively called ''Alakasandu' ...
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Karl Landsteiner
Karl Landsteiner (; 14 June 1868 – 26 June 1943) was an Austrian-born American biologist, physician, and immunologist. He distinguished the main blood groups in 1900, having developed the modern system of classification of blood groups from his identification of the presence of agglutinins in the blood, and in 1937 identified, with Alexander S. Wiener, the Rhesus factor, thus enabling physicians to transfuse blood without endangering the patient's life. With Constantin Levaditi and Erwin Popper, he discovered the polio virus in 1909. He received the Aronson Prize in 1926. In 1930, he received the Nobel Prize in Physiology or Medicine. He was posthumously awarded the Lasker Award in 1946, and has been described as the father of transfusion medicine. Early life and education Born into a Jewish family, Landsteiner's father, Leopold (1818–1875), a renowned Viennese journalist who was editor-in-chief of ''Die Presse'', died at age 56, when Karl was only 6. This led to a close ...
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Rh Blood Group System
The Rh blood group system is a human blood group system. It contains proteins on the surface of red blood cells. After the ABO blood group system, it is the most likely to be involved in transfusion reactions. The Rh blood group system consists of 49 defined blood group antigens, among which the five antigens D, C, c, E, and e are the most important. There is no d antigen. Rh(D) status of an individual is normally described with a ''positive'' (+) or ''negative'' (−) suffix after the ABO type (e.g., someone who is A+ has the A antigen and Rh(D) antigen, whereas someone who is A− has the A antigen but lacks the Rh(D) antigen). The terms ''Rh factor'', ''Rh positive'', and ''Rh negative'' refer to the Rh(D) antigen only. Antibodies to Rh antigens can be involved in hemolytic transfusion reactions and antibodies to the Rh(D) and Rh antigens confer significant risk of hemolytic disease of the fetus and newborn. Nomenclature The Rh blood group system has two sets of nomenclature ...
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