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R-Pharm
R-Pharm is an international pharmaceutical company headquartered in Russia. It reached the headlines in 2020 following approval of its drug "Coronavir" as a treatment in cases of mild to moderate COVID-19 infection. It was founded by Alexey Repik ( ru) in 2001, but has had an increasingly international operations base since, with Japanese Corporation Mitsui & Co., Ltd. acquiring 10% of its shares in 2017. Activity The company's scope of activities covers areas related to the development, research, production, marketing of drugs intended primarily for inpatient and specialized medical care. The main areas of activity are: production of finished dosage forms, active pharmaceutical ingredients of chemical nature and biotechnological substances, research and development of drugs and technologies, introduction to the Russian market of pharmaceuticals. COVID-19 In 2020, during the COVID-19 outbreak in Russia, the company announced its intention to assist in the mass production of the Sp ...
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Sputnik V COVID-19 Vaccine
Sputnik V (russian: Спутник V, the brand name from RDIF) or Gam-COVID-Vac (russian: Гам-КОВИД-Вак, the name under which it is legally registered and produced) is an adenovirus viral vector vaccine for COVID-19 developed by the Gamaleya Research Institute of Epidemiology and Microbiology in Russia. It is the world's first registered combination vector vaccine for the prevention of COVID-19, having been registered on 11 August 2020 by the Russian Ministry of Health. Gam-COVID-Vac was initially approved for distribution in Russia and then in 59 other countries (as of April 2021) on the preliminary results of Phase I– II studies eventually published on 4 September 2020. Approval in early August of Gam-COVID-Vac was met with criticism in mass media and discussions in the scientific community as to whether approval was justified in the absence of robust scientific research confirming safety and efficacy. A large-scale Brazilian study from Dec. 2020 to May 2021 ...
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Coronavir
Coronavir is an anti-viral drug approved in Russia for the treatment of COVID-19. Little is known of this drug, except for the information released by its developer R-Pharm. By the description provided to the press, coronavir seems to be an inhibitor of SARS-CoV-2 RNA polymerase, similar to other antiviral nucleotide analogues such as remdesivir. The drug appears to be based on favipiravir, a drug developed in Japan. Coronavir was approved for use in Russia in hospitals in July 2020, and in September 2020 it received approval for prescription sales for outpatient use. See also * COVID-19 pandemic in Russia The COVID-19 pandemic in Russia is part of the ongoing pandemic of coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (). The virus was confirmed to have spread to Russia on 31 January 2020, when two Ch ... References COVID-19 pandemic in Russia Antiviral drugs Drugs with undisclosed chemical structures {{COVID-19-stub ...
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Russia
Russia (, , ), or the Russian Federation, is a List of transcontinental countries, transcontinental country spanning Eastern Europe and North Asia, Northern Asia. It is the List of countries and dependencies by area, largest country in the world, with its internationally recognised territory covering , and encompassing one-eighth of Earth's inhabitable landmass. Russia extends across Time in Russia, eleven time zones and shares Borders of Russia, land boundaries with fourteen countries, more than List of countries and territories by land borders, any other country but China. It is the List of countries and dependencies by population, world's ninth-most populous country and List of European countries by population, Europe's most populous country, with a population of 146 million people. The country's capital and List of cities and towns in Russia by population, largest city is Moscow, the List of European cities by population within city limits, largest city entirely within E ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ...
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Alexey Repik
Alexey, Alexei, Alexie, Aleksei, or Aleksey (russian: Алексе́й ; bg, Алексей ) is a Russian and Bulgarian male first name deriving from the Greek ''Aléxios'' (), meaning "Defender", and thus of the same origin as the Latin Alexius. Alexey may also be romanized as ''Aleksei'', ''Aleksey'', ''Alexej'', ''Aleksej'', etc. It has been commonly westernized as Alexis. Similar Ukrainian and Belarusian names are romanized as Oleksii (Олексій) and Aliaksiej (Аляксей), respectively. The Russian Orthodox Church uses the Old Church Slavonic version, Alexiy (Алексiй, or Алексий in modern spelling), for its Saints and hierarchs (most notably, this is the form used for Patriarchs Alexius I and Alexius II). The common hypocoristic is Alyosha () or simply Lyosha (). These may be further transformed into Alyoshka, Alyoshenka, Lyoshka, Lyoha, Lyoshenka (, respectively), sometimes rendered as Alesha/Aleshenka in English. The form Alyosha may b ...
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Mitsui
is one of the largest '' keiretsu'' in Japan and one of the largest corporate groups in the world. The major companies of the group include Mitsui & Co. ( general trading company), Sumitomo Mitsui Banking Corporation, Nippon Paper Industries, Pokka Sapporo Holdings, Toray Industries, Mitsui Chemicals, Isetan Mitsukoshi Holdings, Sumitomo Mitsui Trust Holdings, Mitsui Engineering & Shipbuilding, Mitsui O.S.K. Lines and Mitsui Fudosan. History Edo period origins Founded by Mitsui Takatoshi (1622–1694), who was the fourth son of a shopkeeperRíkarðsson, Árni (2020). ''Origins of the Zaibatsu conglomerates''. Bachelor’s thesis. Supervisor: Kristín Ingvarsdóttir. Reykjavik, University of Iceland, p. 15. in Matsusaka, in what is now today's Mie prefecture. From his shop, called Echigoya (越後屋), Mitsui Takatoshi's father originally sold miso and ran a pawn shop business. Later, the family would open a second shop in Edo (now called Tokyo). Takatoshi moved t ...
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Gamaleya Research Institute Of Epidemiology And Microbiology
The Gamaleya Research Institute of Epidemiology and Microbiology,russian: Национальный исследовательский центр эпидемиологии и микробиологии имени почётного академика Н. Ф. Гамалеи, Natsional’nyy isslyedovatyel’skiy tsentr epidyemiologii i mikrobiologii imyeni pochetnogo akadyemika N. F. Gamalyei previously the N. F. Gamaleya Federal Research Center for Epidemiology & Microbiology, is a Russian medical-research institute within the Ministry of Health of the Russian Federation.Other names include the Gamaleya Scientific Research Institute or Gamaleya National Research Center for Epidemiology and Microbiology Founded in 1891 by Filipp Markovich Blyumental, it is named after Soviet scientist Nikolay Fyodorovich Gamaleya (1859–1949), famed as a pioneer in microbiology and in vaccine research. The institute is best known internationally for developing the earliest vaccine for SARS-Co ...
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Oxford–AstraZeneca COVID-19 Vaccine
The Oxford–AstraZeneca COVID19 vaccine, sold under the brand names Covishield and Vaxzevria among others, is a viral vector vaccine for prevention of COVID-19. Developed in the United Kingdom by Oxford University and British-Swedish company AstraZeneca, using as a vector the modified chimpanzee adenovirus ChAdOx1. The vaccine is given by intramuscular injection. Studies carried out in 2020 showed that the efficacy of the vaccine is 76.0% at preventing symptomatic COVID-19 beginning at 22 days following the first dose, and 81.3% after the second dose. A study in Scotland found that, for symptomatic COVID-19 infection after the second dose, the vaccine is 81% effective against the Alpha variant (lineage B.1.1.7), and 61% against the Delta variant (lineage B.1.617.2). The vaccine is stable at refrigerator temperatures and has a good safety profile, with side effects including injection-site pain, headache, and nausea, all generally resolving within a few days. More rarely, ...
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Coronavirus Disease 2019
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, loss of smell, and loss of taste. Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure, shock, or multiorgan dysfunction). Older people are at a higher risk of developing seve ...
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AstraZeneca
AstraZeneca plc () is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England. It has a portfolio of products for major diseases in areas including oncology, cardiovascular, gastrointestinal, infection, neuroscience, respiratory, and inflammation. It has been involved in developing the Oxford–AstraZeneca COVID-19 vaccine. The company was founded in 1999 through the merger of the Swedish Astra AB and the British Zeneca Group (itself formed by the demerger of the pharmaceutical operations of Imperial Chemical Industries in 1993). Since the merger it has been among the world's largest pharmaceutical companies and has made numerous corporate acquisitions, including Cambridge Antibody Technology (in 2006), MedImmune (in 2007), Spirogen (in 2013) and Definiens (by MedImmune in 2014). It has its research and development concentrated in three strategic centres: Cambridge, England; ...
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COVID-19 Pandemic In Russia
The COVID-19 pandemic in Russia is part of the ongoing pandemic of coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (). The virus was confirmed to have spread to Russia on 31 January 2020, when two Chinese citizens in Tyumen (Siberia) and Chita (Russian Far East) tested positive for the virus, with both cases being contained. Early prevention measures included restricting the China–Russia border and extensive testing. The infection spread from Italy on 2 March, leading to additional measures such as cancelling events, closing schools, theatres, and museums, as well as shutting the border and declaring a non-working period which, after two extensions, lasted until 11 May 2020. By the end of March 2020, COVID-19 lockdowns were imposed by the majority of Federal subjects of Russia, including Moscow. By 17 April 2020, cases had been confirmed in all federal subjects. At the beginning of September 2020, the number of COVID-19 cases in Rus ...
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