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Quillay
''Quillaja saponaria'', the soap bark tree or soapbark, is an evergreen tree in the family Quillajaceae, native to warm temperate central Chile. In Chile it occurs from 32 to 40° South Latitude approximately and at up to 2000 m (6500 ft) above sea level. It can grow to 15–20 m (50–65 ft) in height. The tree has thick, dark bark; smooth, leathery, shiny, oval evergreen leaves 3–5 cm long; white star-shaped flowers 15 mm diameter borne in dense corymbs; and a dry fruit with five follicles each containing 10–20 seeds. Characteristics The inner bark of ''Quillaja saponaria'' can be reduced to powder and employed as a substitute for soap, since it forms a lather with water, owing to the presence of a glycoside saponin, sometimes distinguished as quillaia saponin. It's also applied as an agricultural spray adjuvant. The same, or a closely similar substance, is found in soapwort (''Saponaria officinalis''), in senega root (''Polygala senega'') and ...
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Juan Ignacio Molina
Fr. Juan Ignacio Molina (; (June 24, 1740 – September 12, 1829) was a Chilean Jesuit priest, naturalist, historian, translator, geographer, botanist, ornithologist, and linguist. He is usually referred to as Abate Molina (a form of Abbot Molina), and is also sometimes known by the Italian form of his name, Giovanni Ignazio Molina. He was one of the precursors of the theory of the gradual evolution of species, 44 years before Darwin, who repeatedly quoted him in "The Origin of Species". Biography Early years Molina was born at Guaraculén, a big farm located near Villa Alegre ( General Captaincy of Chile), where he lived until he was 5 years old. In the current province of Linares, in the Maule Region of Chile. His parents were Agustín Molina and Francisca González Bruna. From an early age he was attracted to the nature of his environment, and in addition to his school work, he enjoyed observing nature on the family farm, which he visited periodically, alternating wit ...
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Polygala
''Polygala'' is a large genus of flowering plants belonging to the family Polygalaceae. They are commonly known as milkworts or snakeroots. The genus is distributed widely throughout much of the world''Polygala''.
Flora of China.
in zones and the .''Polygala''.
The Jepson eFlora 2013.
The genus name ''Polygala'' comes from the

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QS21
QS-21 is a purified plant extract used as a vaccine adjuvant. It is derived from the soap bark tree (''Quillaja saponaria''), which is native to the countries of Chile, Peru, and Bolivia. The crude drug (''Quillajae cortex'') is imported from Peru and Chile. The extract contains water-soluble triterpene glycosides, which are members of a family of plant-based compounds called saponins. It has been tested as an adjuvant in various vaccines in attempts to improve their efficacy. It is believed to enhance both humoral and cell-mediated immunity. Isolation of QS-21 destroys the soap bark tree, which has resulted in regulation of the tree by the governments where it is grown. A semi-synthesis strategy relies on purifying the prosapogenin (triterpene and branched trisaccharide) part of the molecule and adding the rest of QS-21 synthetically; this is reported to increase the yield by 2 orders of magnitude. This semi-synthetic approach has also facilitated experimentation with a ...
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Vaccine
A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylactic (to prevent ...
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Adjuvant
In pharmacology, an adjuvant is a drug or other substance, or a combination of substances, that is used to increase the efficacy or potency of certain drugs. Specifically, the term can refer to: * Adjuvant therapy in cancer management * Analgesic adjuvant in pain management * Immunologic adjuvant In immunology, an adjuvant is a substance that increases or modulates the immune response to a vaccine. The word "adjuvant" comes from the Latin word ''adiuvare'', meaning to help or aid. "An immunologic adjuvant is defined as any substance that ... in vaccines This is a specialized usage of a word (derived from the Latin verb "adjuvare", ''to help''), which also has a more general meaning as someone or something assisting in any operation or effect. {{sia Adjuvants ...
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Phlegm
Phlegm (; , ''phlégma'', "inflammation", "humour caused by heat") is mucus produced by the respiratory system, excluding that produced by the nasal passages. It often refers to respiratory mucus expelled by coughing, otherwise known as sputum. Phlegm, and mucus as a whole, is in essence a water-based gel consisting of glycoproteins, immunoglobulins, lipids and other substances. Its composition varies depending on climate, genetics, and state of the immune system. Its color can vary from transparent to pale or dark yellow and green, from light to dark brown, and even to dark grey depending on the constituents. The body naturally produces about 1 quart (about 1 litre) of phlegm every day to capture and clear substances in the air and bacteria from the nose and throat. Distinction between mucus and phlegm Contrary to popular misconception and misuse, mucus and phlegm are not always the same. Mucus Mucus is a normal protective layering around the airway, eye, nasal turbinate, ...
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Mucus
Mucus ( ) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glands, which contain both serous and mucous cells. It is a viscous colloid containing inorganic salts, antimicrobial enzymes (such as lysozymes), immunoglobulins (especially IgA), and glycoproteins such as lactoferrin and mucins, which are produced by goblet cells in the mucous membranes and submucosal glands. Mucus serves to protect epithelial cells in the linings of the respiratory, digestive, and urogenital systems, and structures in the visual and auditory systems from pathogenic fungi, bacteria and viruses. Most of the mucus in the body is produced in the gastrointestinal tract. Amphibians, fish, snails, slugs, and some other invertebrates also produce external mucus from their epidermis as protection against pathogens, and to help in movement and is also produced in fish ...
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Foaming Agent
A foaming agent is a material such as a surfactant or a blowing agent that facilitates the formation of foam. A surfactant, when present in small amounts, reduces surface tension of a liquid (reduces the work needed to create the foam) or increases its colloidal stability by inhibiting coalescence of bubbles. A blowing agent is a gas that forms the gaseous part of the foam. Surfactants Sodium laureth sulfate, or sodium lauryl ether sulfate (SLES), is a detergent and surfactant found in many personal care products (soaps, shampoos, toothpastes, etc.). It is an inexpensive and effective foamer. Sodium lauryl sulfate (also known as sodium dodecyl sulfate or SDS) and ammonium lauryl sulfate (ALS) are commonly used alternatives to SLES in consumer products.Sodium Laureth Sulfate POE(2). Chemical Land 21, Seoul, KoreaProduct Identification/ref> Co-surfactants Surfactants which are less effective at foam production, may have additional co-surfactants added to increase foaming. In wh ...
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Pharmaceutical
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell ...
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Food Additive
Food additives are substances added to food to preserve Taste, flavor or enhance taste, appearance, or other sensory qualities. Some additives have been used for centuries as part of an effort to preserve food, for example vinegar (pickling), salt (salting), smoke (Smoking (cooking), smoking), sugar (crystallization), etc. This allows for longer-lasting foods such as bacon, Candy, sweets or wines. With the advent of processed foods in the second half of the twentieth century, many additives have been introduced, of both natural and artificial origin. Food additives also include substances that may be introduced to food indirectly (called "indirect additives") in the manufacturing process, through food packaging, packaging, or during storage or transport. Numbering To regulate these additives and inform consumers, each additive is assigned a unique number called an "E number", which is used in Europe for all approved additives. This numbering scheme has now been adopted and exte ...
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Andes
The Andes, Andes Mountains or Andean Mountains (; ) are the longest continental mountain range in the world, forming a continuous highland along the western edge of South America. The range is long, wide (widest between 18°S – 20°S latitude), and has an average height of about . The Andes extend from north to south through seven South American countries: Venezuela, Colombia, Ecuador, Peru, Bolivia, Chile, and Argentina. Along their length, the Andes are split into several ranges, separated by intermediate depressions. The Andes are the location of several high plateaus—some of which host major cities such as Quito, Bogotá, Cali, Arequipa, Medellín, Bucaramanga, Sucre, Mérida, El Alto and La Paz. The Altiplano plateau is the world's second-highest after the Tibetan plateau. These ranges are in turn grouped into three major divisions based on climate: the Tropical Andes, the Dry Andes, and the Wet Andes. The Andes Mountains are the highest m ...
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Quillaja Saponaria UC Berkeley July 2019 By Amber Kerr
''Quillaja'' is a genus of flowering plants, the only extant genus in the family Quillajaceae with two or three known species. It was once thought to be in the rose family, Rosaceae, but recent research shows it belongs in its own family. The inner bark of the soap bark tree (''Quillaja saponaria, Q. saponaria'') contains saponin, which is a natural soap. Members of this genus are trees that grow to about . Species The species were revised by Luebert in 2014: References

Quillaja, Fabales genera {{Rosid-stub ...
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