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Quigley Scale
The Quigley scale is a descriptive, visual system of phenotypic grading that defines seven classes between "fully masculinized" and "fully feminized" genitalia. It was proposed by pediatric endocrinologist Charmian A. Quigley et al. in 1995. It is similar in function to the Prader scale and is used to describe genitalia in cases of androgen insensitivity syndrome, including complete androgen insensitivity syndrome, partial androgen insensitivity syndrome and mild androgen insensitivity syndrome. Schematic representation Staging The first six grades of the scale, grades 1 through 6, are differentiated by the degree of genital masculinization. Quigley describes the scale as one depicting "severity" or "defective masculinization". Grade 1 is indicated when the external genitalia is fully masculinized, and corresponds to mild androgen insensitivity syndrome. Grades 6 and 7 are indicated when the external genitalia is fully feminized, corresponding to complete androgen insensitivity ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenotype
In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code, or its genotype, and the influence of environmental factors. Both factors may interact, further affecting phenotype. When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic. A well-documented example of polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black, and brown. Richard Dawkins in 1978 and then again in his 1982 book ''The Extended Phenotype'' suggested that one can regard bird nests and other built structures such as cad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terminal Hair
In humans, terminal hair is a variant of hair that is thick and long such as what grows on the scalp, as compared with vellus hair, colloquially known as peach fuzz, growing elsewhere.Marks, James G; Miller, Jeffery (2006)''Lookingbill and Marks' Principles of Dermatology''(4th ed.), Elsevier Inc., p. 11. During puberty, the increase in androgenic hormone levels causes vellus hair to be replaced with terminal hair in certain parts of the human body.Hiort, O. "Androgens and Puberty". ''Best Practice & Research Clinical Endocrinology & Metabolism'', Vol. 16, No. 1, pp. 31–41. These parts will have different levels of sensitivity to androgens, primarily of the testosterone family.Neal, Matthew; Lauren M. Sompayrac''How the Endocrine System Works'' Blackwell Publishing, 2001, p. 75. The pubic area is particularly sensitive to such hormones, as are the armpits which will develop axillary hair.Randall, Valerie A.; Nigel A. Hibberts, M. Julie Thornton, Kazuto Hamada, Alison E. Mer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Male Genital Procedures
Male (symbol: ♂) is the sex of an organism that produces the gamete (sex cell) known as sperm, which fuses with the larger female gamete, or ovum, in the process of fertilization. A male organism cannot reproduce sexually without access to at least one ovum from a female, but some organisms can reproduce both sexually and asexually. Most male mammals, including male humans, have a Y chromosome, which codes for the production of larger amounts of testosterone to develop male reproductive organs. Not all species share a common sex-determination system. In most animals, including humans, sex is determined genetically; however, species such as ''Cymothoa exigua'' change sex depending on the number of females present in the vicinity. In humans, the word ''male'' can also be used to refer to gender in the social sense of gender role or gender identity. Overview The existence of separate sexes has evolved independently at different times and in different lineages, an example of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex Assignment
Sex assignment (sometimes known as gender assignment) is the discernment of an infant's sex at or before birth. A relative, midwife, nurse or physician inspects the external genitalia when the baby is delivered and, in more than 99.95% of births, sex is assigned without ambiguity. Assignment may also be done prior to birth through prenatal sex discernment. The sex assignment at or before birth usually aligns with a child's anatomical sex and phenotype. The number of births where the baby is intersex—where they do not fit into typical definitions of male and female at birth—has been reported to be as low as 0.018%, but is often estimated at around 0.2%. The number of births with ambiguous genitals is in the range of 0.02% to 0.05%. These conditions may complicate sex assignment. Other intersex conditions involve atypical chromosomes, gonads or hormones. Reinforcing sex assignments through surgical or hormonal interventions is often considered to violate the individual's huma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ambiguous Genitalia
Intersex people are individuals born with any of several sex characteristics including chromosome patterns, gonads, or genitals that, according to the Office of the United Nations High Commissioner for Human Rights, "do not fit typical binary notions of male or female bodies". Sex assignment at birth usually aligns with a child's anatomical sex and phenotype. The number of births with ambiguous genitals is in the range of 1:2000–1:4500 (0.022%–0.05%). Other conditions involve atypical chromosomes, gonads, or hormones. Some persons may be assigned and raised as a girl or boy but then identify with another gender later in life, while most continue to identify with their assigned sex. The number of births where the baby is intersex has been reported differently depending on who reports and which definition of intersex is used. Anne Fausto-Sterling and her co-authors suggest that the prevalence of "nondimorphic sexual development" might be as high as 1.7%. A study publish ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phall-O-Meter
The Phall-O-meter is a satirical measure that critiques medical standards for normal male and female phalluses. The tool was developed by Kiira Triea (Denise Tree) based on a concept by Suzanne Kessler and is used to demonstrate concerns with the medical treatment of intersex bodies. Schematic representation History The Phall-O-meter was developed by Kiira Triea based on a concept by professor of psychology Suzanne Kessler. Kessler summarized the range of medically acceptable infant penis and clitoris sizes in the book ''Lessons from the Intersexed''. Kessler states that normative tables for clitoral length appeared in the late 1980s, while normative tables for penis length appeared more than forty years before that. She combined those standard tables to demonstrate an "intermediate area of phallic length that neither females nor males are permitted to have", that is, a clitoris larger than 9mm or a penis shorter than 25mm. The meter was printed by the now-defunct Intersex Socie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Orchidometer
An orchidometer (or orchiometer) is a medical instrument used to measure the volume of the testicles. The orchidometer was introduced in 1966 by Swiss pediatric endocrinologist Andrea Prader of the University of Zurich. It consists of a string of twelve numbered wooden or plastic beads of increasing size from about 1 to 25 millilitres. Doctors sometimes informally refer to them as "Prader's balls", "the medical worry beads", or the "endocrine rosary". The beads are compared with the testicles of the patient, and the volume is read off the bead which matches most closely in size. Prepubertal sizes are 1–3 ml, pubertal sizes are considered 4 ml and up and adult sizes are 15-25 ml. The orchidometer can be used to accurately determine size of testes. Discrepancy of testicular size with other parameters of maturation can be an important clue to various diseases. Small testes can indicate either primary or secondary hypogonadism. Testicular size can help distinguish between differen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Council Of Europe
The Council of Europe (CoE; french: Conseil de l'Europe, ) is an international organisation founded in the wake of World War II to uphold European Convention on Human Rights, human rights, democracy and the Law in Europe, rule of law in Europe. Founded in 1949, it has 46 member states, with a population of approximately 675 million; it operates with an annual budget of approximately 500 million euros. The organisation is distinct from the European Union (EU), although it is sometimes confused with it, partly because the EU has adopted the original Flag of Europe, European flag, created for the Council of Europe in 1955, as well as the Anthem of Europe, European anthem. No country has ever joined the EU without first belonging to the Council of Europe. The Council of Europe is an official United Nations General Assembly observers, United Nations Observer. Being an international organization, the Council of Europe cannot make laws, but it does have the ability to push for the enf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Secondary Sex Characteristic
Secondary sex characteristics are features that appear during puberty in humans, and at sexual maturity in other animals. These characteristics are particularly evident in the sexually dimorphic phenotypic traits that distinguish the sexes of a species, but unlike the sex organs (primary sex characteristics), are not directly part of the reproductive system. Secondary sex characteristics are believed to be the product of sexual selection for traits which display fitness, giving an organism an advantage over its rivals in courtship and in aggressive interactions. Secondary sex characteristics include, for example, the manes of male lions, the bright facial and rump coloration of male mandrills, and horns in many goats and antelopes. These characteristics are believed to be produced by a positive feedback loop known as the Fisherian runaway produced by the secondary characteristic in one sex and the desire for that characteristic in the other sex. Male birds and fish of many species ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrinologist
Endocrinology (from ''endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a duct system. Therefore, endocrine glands are regarded as ductless glands. Hormones have many different functions and modes of action; one hormone may have several effects on different target organs, and, conversely, one target org ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Development Of The Reproductive System
The development of the reproductive system is the part of embryonic growth that results in the sex organs and contributes to sexual differentiation. Due to its large overlap with development of the urinary system, the two systems are typically described together as the urogenital or genitourinary system. The reproductive organs develop from the intermediate mesoderm and are preceded by more primitive structures that are superseded before birth. These embryonic structures are the mesonephric ducts (also known as ''Wolffian ducts'') and the paramesonephric ducts, (also known as ''Müllerian ducts''). The mesonephric duct gives rise to the male seminal vesicles, epididymes and vas deferens. The paramesonephric duct gives rise to the female fallopian tubes, uterus, cervix, and upper part of the vagina. Mesonephric ducts The mesonephric duct originates from a part of the pronephric duct. Origin In the outer part of the intermediate mesoderm, immediately under the ectoderm, in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quigley Scale For Androgen Insensitivity Syndrome
Quigley is a surname of Irish origin derived from the Gaelic ''Ó Coigligh'' meaning "descendant of Coigleach (male)" or ''Ní Choigligh'' meaning "descendant of Coigleach (female)." Variations include: O'Quigley, Cogley, Quigly, Quigg, MacQuigg, McQuigge, O'Quigg, Twigg and Fivey. The name may refer to: * Allie Quigley, American basketball player * Brett Quigley (born 1969), American golfer *Carroll Quigley (1910–1977), American writer and history professor * Colleen Quigley (born 1992), American distance runner and Olympian *Dana Quigley (born 1947), American golfer * Dawn Quigley, Ojibwe-American author and educator * Dennis Quigley (1913–1984), Scottish footballer *Derek Quigley (born 1932), New Zealand politician *Eddie Quigley (1921–1997), English footballer and manager * Ernie Quigley (1880–1960), Canadian-American sports official * Fannie Quigley (1870–1944), Alaskan pioneer and prospector *James Edward Quigley (1854–1915), Canadian-American archbishop * Ja ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
