Panax Notoginseng
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Panax Notoginseng
''Panax notoginseng'' is a species of the genus ''Panax'', and it is commonly referred to in English as Chinese ginseng * or notoginseng. In Chinese it is called ''tiánqī'' (), tienchi ginseng, ''sānqī'' () or ''sanchi'', three-seven root, and mountain plant. ''P. notoginseng'' belongs to the same scientific genus as ''Panax ginseng''. In Latin, the word ''panax'' means "cure-all", and the family of ginseng plants is one of the best-known herbs. ''P. notoginseng'' grows naturally in China. The herb is a perennial with dark green leaves branching from a stem with a red cluster of berries in the middle. It is both cultivated and gathered from wild forests, with wild plants being the most valuable. The Chinese refer to it as three-seven root because the plant has three petioles with seven leaflets each. It is also said that the root should be harvested between three and seven years after planting it. Chinese medicine In traditional Chinese medicine, ''P. notoginseng'' ...
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Decoction
Decoction is a method of extraction by boiling herbal or plant material (which may include stems, roots, bark and rhizomes) to dissolve the chemicals of the material. It is the most common preparation method in various herbal-medicine systems. Decoction involves first drying the plant material; then mashing, slicing, or cutting the material to allow for maximum dissolution; and finally boiling in water to extract oils, volatile organic compounds and other various chemical substances. Occasionally, aqueous ethanol or glycerol may be used instead of water. Decoction can be used to make tisanes, tinctures and similar solutions. Decoctions and infusions may produce liquids with differing chemical properties, as the temperature or preparation difference may result in more oil-soluble chemicals in decoctions versus infusions. The process can also be applied to meats and vegetables to prepare bouillon or stock, though the term is typically only used to describe boiled plant extracts, usua ...
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Ginsenoside Rb1
Ginsenoside Rb1 (or Ginsenoside Rb1 or GRb1 or GRb1) is a chemical compound belonging to the ginsenoside family. Like other ginsenosides, it is found in the plant genus '' Panax'' ( ginseng), and has a variety of potential health effects including anticarcinogenic, immunomodulatory, anti‐inflammatory, antiallergic, antiatherosclerotic, antihypertensive, and antidiabetic effects as well as antistress activity and effects on the central nervous system. Pharmacological effects A 1998 study by Seoul National University reported that GRb1 and GRg3 (ginsenosides Rb1 and Rg3) significantly attenuated glutamate-induced neurotoxicity by inhibiting the overproduction of nitric oxide synthase among some other findings regarding their neuroprotective properties. In 2002, the Laboratory for Cancer Research in Rutgers University showed that GRb1 and GRg1 have neuroprotective effect for spinal cord neurons, while ginsenoside Re did not exhibit any activity. GRb1 and GRg1 are pro ...
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Protopanaxatriol
Protopanaxatriol (PPT) is an organic compound characterizing a group of ginsenosides. It is a dammarane-type tetracyclic triterpene sapogenins found in ginseng (''Panax ginseng'') and in notoginseng ''Panax notoginseng'' is a species of the genus ''Panax'', and it is commonly referred to in English as Chinese ginseng * or notoginseng. In Chinese it is called ''tiánqī'' (), tienchi ginseng, ''sānqī'' () or ''sanchi'', three-seven root, a ... (''Panax pseudoginseng''). See also * Panaxatriol * Protopanaxadiol References {{alcohol-stub Triterpenes Tetrols Steroids ...
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Protopanaxadiol
Protopanaxadiol (PPD) is an organic compound characterizing a group of ginsenosides. It is a dammarane-type tetracyclic terpene sapogenin found in ginseng (''Panax ginseng'') and in notoginseng (''Panax pseudoginseng''). Just what protopanaxadiol's metabolites do inside the human body is still unclear. One study suggests it has rapid, non-genomic effects on endothelial cells, binding to the glucocorticoid and oestrogen beta receptors. The study also showed an increase of intracellular calcium ion concentration. See also * Protopanaxatriol Protopanaxatriol (PPT) is an organic compound characterizing a group of ginsenosides. It is a dammarane-type tetracyclic triterpene sapogenins found in ginseng (''Panax ginseng'') and in notoginseng (''Panax pseudoginseng''). See also * Panaxatr ... References Triterpenes Triols Steroids {{alcohol-stub ...
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Ginsenosides
Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus ''Panax'' (ginseng), which has a long history of use in traditional medicine that has led to the study of pharmacological effects of ginseng compounds. As a class, ginsenosides exhibit a large variety of subtle and difficult-to-characterize biological effects when studied in isolation. Ginsenosides can be isolated from various parts of the plant, though typically from the roots, and can be purified by column chromatography. The chemical profiles of ''Panax'' species are distinct; although Asian ginseng, ''Panax ginseng'', has been most widely studied due to its use in traditional Chinese medicine, there are ginsenosides unique to American ginseng (''Panax quinquefolius'') and Japanese ginseng (''Panax japonicus''). Ginsenoside content also varies significantly due to environmental effects. Classification G ...
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Dammarane
Dammarane is a tetracyclic triterpene found in sapogenins (forming triterpenoid saponins) like those of ginseng ( ginsenosides: panaxatriol and protopanaxadiol). Compounds of the series were first isolated from and named after dammar resin Dammar, also called dammar gum, or damar gum, is a resin obtained from the tree family Dipterocarpaceae in India and Southeast Asia, principally those of the genera ''Shorea'' or ''Hopea'' (synonym ''Balanocarpus''). The resin of some species ..., a natural resin from tropical trees of the Dipterocarp family. Mills J.S. (1956) "The Constitution of the Neutral, Tetracyclic Triterpenes of Dammar Resin" ''Journal of the Chemical Society'' 2196-2202 References External links Numbering of dammarane according to IUPAC Recommendations Steroids Triterpenes {{steroid-stub ...
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Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, literati theory and Confucian philosophy, herbal remedies, food, diet, exercise, medical specializations, and schools of thought. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selected elements of philosophy and practice and organized them into what they called "Chinese medicine" (''Zhongyi''). In the 1950s, the Chinese government sponsored the integration of Chinese and Western medicine, and in the Great Proletarian Cultural Revolution of the 1960s, promoted Chinese medicine as inexpensive a ...
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Species
In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. Other ways of defining species include their karyotype, DNA sequence, morphology, behaviour or ecological niche. In addition, paleontologists use the concept of the chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. However, only about 14% of these had been described by 2011. All species (except viruses) are given a two-part name, a "binomial". The first part of a binomial is the genus to which the species belongs. The second part is called the specific name or the specific epithet (in botanical nomenclature, also sometimes i ...
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Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, literati theory and Confucian philosophy, herbal remedies, food, diet, exercise, medical specializations, and schools of thought. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selected elements of philosophy and practice and organized them into what they called "Chinese medicine" (''Zhongyi''). In the 1950s, the Chinese government sponsored the integration of Chinese and Western medicine, and in the Great Proletarian Cultural Revolution of the 1960s, promoted Chinese medicine as inexpensive a ...
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China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or dyna ...
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