Psychoneuroimmunology Research Society
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Psychoneuroimmunology Research Society
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI) or psychoneuroendocrinoimmunology (PNEI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. It is a subfield of psychosomatic medicine. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology. The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, i ...
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Psychosomatic Medicine
Psychosomatic medicine is an interdisciplinary medical field exploring the relationships among social, psychological, behavioral factors on bodily processes and quality of life in humans and animals. The academic forebear of the modern field of behavioral medicine and a part of the practice of consultation-liaison psychiatry, psychosomatic medicine integrates interdisciplinary evaluation and management involving diverse specialties including psychiatry, psychology, neurology, psychoanalysis, internal medicine, pediatrics, surgery, allergy, dermatology, and psychoneuroimmunology. Clinical situations where mental processes act as a major factor affecting medical outcomes are areas where psychosomatic medicine has competence. Psychosomatic disorders Some physical diseases are believed to have a mental component derived from stresses and strains of everyday living. This has been suggested, for example, of lower back pain and high blood pressure, which some researchers have sugge ...
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Hypersensitivity
Hypersensitivity (also called hypersensitivity reaction or intolerance) refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an over-reaction of the immune system and these reactions may be damaging and uncomfortable. This is an immunologic term and is not to be confused with the psychiatric term of being hypersensitive which implies to an individual who may be overly sensitive to physical (i.e. sound, touch, light, etc.) and/or emotional stimuli. Although there is a relation between the two – studies have shown that those individuals that have ADHD (a psychiatric disorder) are more likely to have hypersensitivity reactions such as allergies, asthma, eczema than those who do not have ADHD. Hypersensitivity reactions can be classified into four types. Type I: IgE mediated immediate reaction Type II: Antibody-mediated reaction (IgG or IgM antibodies) Type III: Immune complex-mediated rea ...
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Ancient Greek
Ancient Greek includes the forms of the Greek language used in ancient Greece and the ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Dark Ages (), the Archaic period (), and the Classical period (). Ancient Greek was the language of Homer and of fifth-century Athenian historians, playwrights, and philosophers. It has contributed many words to English vocabulary and has been a standard subject of study in educational institutions of the Western world since the Renaissance. This article primarily contains information about the Epic and Classical periods of the language. From the Hellenistic period (), Ancient Greek was followed by Koine Greek, which is regarded as a separate historical stage, although its earliest form closely resembles Attic Greek and its latest form approaches Medieval Greek. There were several regional dialects of Ancient Greek, of which Attic Greek developed into Koine. Dia ...
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Homeostasis
In biology, homeostasis (British English, British also homoeostasis) Help:IPA/English, (/hɒmɪə(ʊ)ˈsteɪsɪs/) is the state of steady internal, physics, physical, and chemistry, chemical conditions maintained by organism, living systems. This is the condition of optimal functioning for the organism and includes many variables, such as body temperature and fluid balance, being kept within certain pre-set limits (homeostatic range). Other variables include the pH of extracellular fluid, the concentrations of sodium, potassium and calcium ions, as well as that of the blood sugar level, and these need to be regulated despite changes in the environment, diet, or level of activity. Each of these variables is controlled by one or more regulators or homeostatic mechanisms, which together maintain life. Homeostasis is brought about by a natural resistance to change when already in the optimal conditions, and equilibrium is maintained by many regulatory mechanisms: it is thought to be ...
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Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ...
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Walter Cannon
Walter Bradford Cannon (October 19, 1871 – October 1, 1945) was an American physiologist, professor and chairman of the Department of Physiology at Harvard Medical School. He coined the term "fight or flight response", and developed the theory of homeostasis. He popularized his theories in his book ''The Wisdom of the Body'', first published in 1932. Life and career Cannon was born on October 19, 1871, in Prairie du Chien, Wisconsin, the son of Colbert Hanchett Cannon and his wife Wilma Denio. His sister Ida Maud Cannon (1877-1960) became a noted hospital social worker at Massachusetts General Hospital. In his autobiography ''The Way of an Investigator'', Cannon counts himself among the descendants of Jacques de Noyon, a French Canadian explorer and coureur des bois. His Calvinist family was intellectually active, including readings from James Martineau, John Fiske (philosopher), and James Freeman Clarke. Cannon's curiosity also led him to Thomas Henry Huxley, John Tyndall, Geo ...
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Milieu Interieur
The internal environment (or ''milieu intérieur'' in French language, French) was a concept developed by Claude Bernard, a French physiologist in the 19th century, to describe the Extracellular fluid#Interstitial fluid, interstitial fluid and its physiology, physiological capacity to ensure protective stability for the Tissue (biology), tissues and organ (anatomy), organs of multicellular organisms. Etymology Claude Bernard used the French phrase ''milieu intérieur'' (internal environment in English) in several works from 1854 until his death in 1878. He most likely adopted it from the histologist Charles-Philippe Robin, Charles Robin, who had employed the phrase "milieu de l’intérieur" as a synonym for the ancient Hippocrates, hippocratic idea of humors. Bernard was initially only concerned with the role of the blood but he later included that of the whole body in ensuring this internal stability.Gross, C. G. (1998"Claude Bernard and the constancy of the internal environmen ...
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English Language
English is a West Germanic language of the Indo-European language family, with its earliest forms spoken by the inhabitants of early medieval England. It is named after the Angles, one of the ancient Germanic peoples that migrated to the island of Great Britain. Existing on a dialect continuum with Scots, and then closest related to the Low Saxon and Frisian languages, English is genealogically West Germanic. However, its vocabulary is also distinctively influenced by dialects of France (about 29% of Modern English words) and Latin (also about 29%), plus some grammar and a small amount of core vocabulary influenced by Old Norse (a North Germanic language). Speakers of English are called Anglophones. The earliest forms of English, collectively known as Old English, evolved from a group of West Germanic (Ingvaeonic) dialects brought to Great Britain by Anglo-Saxon settlers in the 5th century and further mutated by Norse-speaking Viking settlers starting in the 8th and 9th ...
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Muséum National D'Histoire Naturelle
The French National Museum of Natural History, known in French as the ' (abbreviation MNHN), is the national natural history museum of France and a ' of higher education part of Sorbonne Universities. The main museum, with four galleries, is located in Paris, France, within the Jardin des Plantes on the left bank of the River Seine. It was formally founded in 1793 during the French Revolution, but was begun even earlier in 1635 as the royal garden of medicinal plants. The museum now has 14 sites throughout France. History 17th–18th century File:Jardin du roi 1636.png, The Royal Garden of Medicinal Plants in 1636 File:Buffon statue dsc00979.jpg, Statue of Georges-Louis Leclerc, Comte de Buffon in the formal garden File:Buffon, Georges Louis - Leclerc, comte de – Histoire naturelle, générale et particuliére, 1763 – BEIC 8822844.jpg, Buffon's "Natural History" (1763) File:MNHN-logo.jpg, The museum's seal, designed in 1793, illustrates the three realms of Nature, Collecti ...
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Claude Bernard
Claude Bernard (; 12 July 1813 – 10 February 1878) was a French physiologist. Historian I. Bernard Cohen of Harvard University called Bernard "one of the greatest of all men of science". He originated the term ''milieu intérieur'', and the associated concept of homeostasis (the latter term being coined by Walter Cannon). Life and career Bernard was born in 1813 in the village of Saint-Julien near Villefranche-sur-Saône. He received his early education in the Jesuit school of that town, and then proceeded to the college at Lyon, which, however, he soon left to become assistant in a druggist's shop. He is sometimes described as an agnostic and even humorously referred to by his colleagues as a "great priest of atheism". Despite this, after his death Cardinal Ferdinand Donnet claimed Bernard was a fervent Catholic, with a biographical entry in the ''Catholic Encyclopedia''. His leisure hours were devoted to the composition of a vaudeville comedy, and the success it achieved ...
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Claude Bernard And His Pupils
Claude may refer to: __NOTOC__ People and fictional characters * Claude (given name), a list of people and fictional characters * Claude (surname), a list of people * Claude Lorrain (c. 1600–1682), French landscape painter, draughtsman and etcher traditionally called just "Claude" in English * Madame Claude, French brothel keeper Fernande Grudet (1923–2015) Places * Claude, Texas, a city * Claude, West Virginia, an unincorporated community Other uses * Allied reporting name of the Mitsubishi A5M Japanese carrier-based fighter aircraft * Claude (alligator) Claude is an albino alligator ('' Alligator mississippiensis'') at the California Academy of Sciences. Claude lacks the pigment melanin, resulting in colorless skin, and he has poor eyesight associated with his albinism. Background Claude was ha ..., an albino alligator at the California Academy of Sciences See also * Claude's syndrome, a form of brainstem stroke syndrome {{disambig, geo ...
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In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done ''in vitro'' ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In dr ...
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