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Propanolamines
Propanolamines are a class of chemical compounds, many of which are pharmaceutical drugs. They are amino alcohols that are derivatives of 1-amino-2-propanol. Propanolamines include: * Acebutolol * Atenolol * Betaxolol * Bisoprolol * Metoprolol * Nadolol * Penbutolol * Phenylpropanolamine * Pindolol * Practolol * Propranolol * Ritodrine * Timolol See also * Propanolamine In organic chemistry, propanolamine can describe any of the following Parent structure, parent compounds: *2-Amino-1-propanol, the hydrogenated derivative of alanine. *3-Amino-1-propanol, straight-chain and not widely used. *3-Amino-2-propanol (1- ... External links * References {{amine-stub Amino alcohols ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aminopropanol
In organic chemistry, propanolamine can describe any of the following parent compounds: * 2-Amino-1-propanol, the hydrogenated derivative of alanine. *3-Amino-1-propanol, straight-chain and not widely used. *3-Amino-2-propanol (1-Aminopropan-2-ol) (isopropanolamines), prepared by addition of amines to one or two equivalents of propylene oxide. The propanolamines Propanolamines are a class of chemical compounds, many of which are pharmaceutical drugs. They are amino alcohols that are derivatives of 1-amino-2-propanol. Propanolamines include: * Acebutolol * Atenolol * Betaxolol * Bisoprolol * M ... include many derivatives where the amine is secondary or tertiary. The parent propanolamines are colorless liquids with the formula {{chem2, C3H9NO. References Amino alcohols ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amino Alcohol
In organic chemistry, alkanolamines are organic compounds that contain both hydroxyl () and amino (, , and ) functional groups on an alkane backbone. The term alkanolamine is a broad class term that is sometimes used as a subclassification. Methanolamine.svg, methanolamine, an intermediate in the reaction of ammonia with formaldehyde Ethanolamine.png, Ethanolamine 2-amino-2-methyl-1-propanol.svg, 2-amino-2-methyl-1-propanol is a precursor to oxazolines valinol.svg, valinol is derived from the amino acid valine Sphingosine structure.svg, Sphingosine is a component of some cell membrane. 1-Aminoalcohols 1-Aminoalcohols are better known as hemiaminals. Methanolamine is the simplest member. 2-Aminoalcohols Key members: ethanolamine, dimethylethanolamine, ''N''-methylethanolamine, Aminomethyl propanol Two popular drugs, often called alkanolamine beta blockers, are members of this structural class: propranolol, pindolol. Isoetarine is yet another medicinally useful derivative o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Propanolamine
In organic chemistry, propanolamine can describe any of the following parent compounds: * 2-Amino-1-propanol, the hydrogenated derivative of alanine. *3-Amino-1-propanol, straight-chain and not widely used. *3-Amino-2-propanol (1-Aminopropan-2-ol) (isopropanolamines), prepared by addition of amines to one or two equivalents of propylene oxide. The propanolamines Propanolamines are a class of chemical compounds, many of which are pharmaceutical drugs. They are amino alcohols that are derivatives of 1-amino-2-propanol. Propanolamines include: * Acebutolol * Atenolol * Betaxolol * Bisoprolol * M ... include many derivatives where the amine is secondary or tertiary. The parent propanolamines are colorless liquids with the formula {{chem2, C3H9NO. References Amino alcohols ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nadolol
Nadolol, sold under the brand name Corgard among others, is a medication used to treat high blood pressure, heart pain, atrial fibrillation, and some inherited arrhythmic syndromes. It has also been used to prevent migraine headaches and complications of cirrhosis. It is taken orally. Common side effects include dizziness, feeling tired, a slow heart rate, and Raynaud syndrome. Serious side effects may include heart failure and bronchospasm. Its use in pregnancy and breastfeeding is of unclear safety. It is a non-selective beta blocker and works by blocking β1-adrenergic receptors in the heart and β2-adrenergic receptors in blood vessels. Nadolol was patented in 1970 and came into medical use in 1978. It is available as a generic medication. In 2020, it was the 340th most commonly prescribed medication in the United States, with more than 700thousand prescriptions. Medical uses Nadolol is used to treat hypertension and for long-term treatment of angina pectoris and is ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pindolol Skeletal
Pindolol, sold under the brand name Visken among others, is a nonselective beta blocker which is used in the treatment of hypertension.Drugs.coInternational brand names for pindolol Page accessed Sept 4, 2015 It is also an antagonist of the serotonin 5-HT1A receptor, preferentially blocking inhibitory 5-HT1A autoreceptors, and has been researched as an add-on therapy to selective serotonin reuptake inhibitors (SSRIs) in the treatment of depression. Medical uses Pindolol is used for hypertension in the United States, Canada, and Europe, and also for angina pectoris outside the United States. When used alone for hypertension, pindolol can significantly lower blood pressure and heart rate, but the evidence base for its use is weak as the number of subjects in published studies is small. In some countries, pindolol is also used for arrhythmias and prophylaxis of acute stress reactions. Contraindications Similar to propranolol with an extra contraindication for hyperthyro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Propranolol
Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker class. It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors, as well to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. It can be taken by mouth or by injection into a vein. The formulation that is taken by mouth comes in short-acting and long-acting versions. Propranolol appears in the blood after 30 minutes and has a maximum effect between 60 and 90 minutes when taken by mouth. Common side effects include nausea, abdominal pain, and constipation. It should not be used in those with an already slow heart rate and most of those with heart failure. Quickly stopping the medication in those with coronary artery disease may worsen symptoms. It may worsen the symptoms of asthma. Caution is recommended in those ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Timolol
Timolol is a beta blocker medication used either by mouth or as eye drops. As eye drops it is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma. By mouth it is used for high blood pressure, chest pain due to insufficient blood flow to the heart, to prevent further complications after a heart attack, and to prevent migraines. Common side effects with the drops is irritation of the eye. Common side effects by mouth include tiredness, slow heart beat, itchiness, and shortness of breath. Other side effects include masking the symptoms of low blood sugar in those with diabetes. Use is not recommended in those with asthma, uncompensated heart failure, or COPD. It is unclear if use during pregnancy is safe for the baby. Timolol is a non-selective beta blocker. Timolol was patented in 1968, and came into medical use in 1978. It is on the World Health Organization's List of Essential Medicines. Timolol is available as a generic medicatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metoprolol
Metoprolol, sold under the brand name Lopressor, among others, is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. By working on the beta-1 receptor of the cardiac muscle cells, it yields both a chronotropic and inotropic effect. It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines. Metoprolol is sold in formulations that can be taken by mouth or given intravenously. The medication is often taken twice a day. The extended-release formulation, metoprolol succinate, is taken once per day. Metoprolol may be combined with hydrochlorothiazide (a diuretic) in a single tablet. Common side effects include trouble sleeping, feeling tired, feeling faint, and abdominal discomfort. Large doses may cause serious toxicity. Risk in pregnancy has not been ruled o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-amino-2-propanol
1-Aminopropan-2-ol is the organic compound with the formula CH3CH(OH)CH2NH2. It is an amino alcohol. The term ''isopropanolamine'' may also refer more generally to the additional homologs diisopropanolamine (DIPA) and triisopropanolamine (TIPA). 1-Aminopropan-2-ol is chiral. It can be prepared by the addition of aqueous ammonia to propylene oxide. Biosynthesis (''R'')-1-Aminopropan-2-ol is one of the components incorporated in the biosynthesis of cobalamin. The ''O''-phosphate ester is produced from threonine by the enzyme Threonine-phosphate decarboxylase. Applications The isopropanolamines are used as buffers. They are good solubilizers of oil and fat, so they are used to neutralize fatty acids and sulfonic acid-based surfactants. Racemic 1-aminopropan-2-ol is typically used in metalworking fluid, waterborne coatings, personal care products, and in the production of titanium dioxide and polyurethanes. It is an intermediate in the synthesis of a variety of pharmaceutical dru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Betaxolol
Betaxolol is a selective beta1 receptor blocker used in the treatment of hypertension and angina. Being selective for beta1 receptors, it typically has fewer systemic side effects than non-selective beta-blockers, for example, not causing bronchospasm (mediated by beta2 receptors) as timolol may. Betaxolol also shows greater affinity for beta1 receptors than metoprolol. In addition to its effect on the heart, betaxolol reduces the pressure within the eye (intraocular pressure). This effect is thought to be caused by reducing the production of the liquid (which is called the aqueous humor) within the eye. The precise mechanism of this effect is not known. The reduction in intraocular pressure reduces the risk of damage to the optic nerve and loss of vision in patients with elevated intraocular pressure due to glaucoma. It was patented in 1975 and approved for medical use in 1983. Medical uses Hypertension Betaxolol is most commonly ingested orally alone or with other medica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atenolol
Atenolol is a beta blocker medication primarily used to treat high blood pressure and heart-associated chest pain. Atenolol, however, does not seem to improve mortality in those with high blood pressure. Other uses include the prevention of migraines and treatment of certain irregular heart beats. It is taken by mouth or by injection into a vein. It can also be used with other blood pressure medications. Common side effects include feeling tired, heart failure, dizziness, depression, and shortness of breath. Other serious side effects include bronchospasm. Use is not recommended during pregnancy and alternative drugs are preferred when breastfeeding. It works by blocking β1-adrenergic receptors in the heart, thus decreasing the heart rate and workload. Atenolol was patented in 1969 and approved for medical use in 1975. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 53rd most commonly presc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bisoprolol
Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker medication used for heart diseases. This includes tachyarrhythmias, high blood pressure, chest pain from not enough blood flow to the heart, and heart failure. It is taken by mouth. Common side effects include headache, feeling tired, diarrhea, and swelling in the legs. More severe side effects include worsening asthma, blocking the ability to recognize low blood sugar, and worsening heart failure. There are concerns that use during pregnancy may be harmful to the baby. Bisoprolol is in the beta blocker family of medications and is of the β1 selective type. Bisoprolol is on the World Health Organization's List of Essential Medicines. Bisoprolol is available as a generic medication. In 2020, it was the 267th most commonly prescribed medication in the United States, with more than 1million prescriptions. Medical uses Bisoprolol is currently used for prevention of cardiovascular events following a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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