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Prevotella Melaninogenica
''Prevotella melaninogenica'' is a species of bacterium in the normal microbiota of the upper respiratory tract. It is an important human pathogen in various anaerobic infections, often mixed with other aerobic and anaerobic bacteria. ''P. melaninogenica'' is an anaerobic, Gram-negative rod, named for its black colonies, and black pigment. ''P. melaninogenica'' is associated with hypertension together with ''Campylobacter rectus'' and ''Veillonella parvula''. Description ''P. melaninogenica'' are Gram-negative rod-shaped bacteria. They cannot survive in the presence of oxygen. They are not motile, and do not form spores. ''P. melaninogenica'' grow well on blood agar, where they form circular dark-colored colonies that darken over one to two weeks. History ''P. melaninogenica'' was originally described as ''Bacteroides melaninogenicus'' in 1921 by Wade Oliver and William Wherry at the University of Cincinnati as a new bacterium isolated from various sites of several different hu ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationsh ...
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Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as ''Pseudomonas aeruginosa'', ''Chlamydia trachomatis'', and ''Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex lipo ...
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Bacteroides Loescheii
''Bacteroides'' is a genus of Gram-negative, obligate anaerobic bacteria. ''Bacteroides'' species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. The DNA base composition is 40–48% GC. Unusual in bacterial organisms, ''Bacteroides'' membranes contain sphingolipids. They also contain meso-diaminopimelic acid in their peptidoglycan layer. ''Bacteroides'' species are normally mutualistic, making up the most substantial portion of the mammalian gastrointestinal microbiota, where they play a fundamental role in processing of complex molecules to simpler ones in the host intestine. As many as 1010–1011 cells per gram of human feces have been reported. They can use simple sugars when available; however, the main sources of energy for ''Bacteroides'' species in the gut are complex host-derived and plant glycans. Studies indicate that long-term diet is strongly associated with the gut microbiome composition—those who eat plenty ...
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University Of Cincinnati
The University of Cincinnati (UC or Cincinnati) is a public research university in Cincinnati, Ohio. Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 44,000 students, making it the second largest university in Ohio. It is part of the University System of Ohio. The university has four major campuses, with Cincinnati's main uptown campus and medical campus in the Heights and Corryville neighborhoods, and branch campuses in Batavia and Blue Ash, Ohio. The university has 14 constituent colleges, with programs in architecture, business, education, engineering, humanities, the sciences, law, music, and medicine. The medical college includes a leading teaching hospital and several biomedical research laboratories, with developments made including a live polio vaccine and diphenhydramine. UC was also the first university to implement a co-operative education (co-op) model. The university is accre ...
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Blood Agar
An agar plate is a Petri dish that contains a growth medium solidified with agar, used to Microbiological culture, culture microorganisms. Sometimes selective compounds are added to influence growth, such as antibiotics. Individual microorganisms placed on the plate will grow into individual colony (biology), colonies, each a cloning, clone genetically identical to the individual ancestor organism (except for the low, unavoidable rate of mutation). Thus, the plate can be used either to estimate the concentration of organisms in a Microbiological culture, liquid culture or a suitable dilution of that culture using a colony counter, or to generate genetically pure cultures from a mixed culture of genetically different organisms. Several methods are available to plate out cells. One technique is known as "Streaking (microbiology), streaking". In this technique, a drop of the culture on the end of a thin, sterilization (microbiology), sterile loop of wire, sometimes known as an inocu ...
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Bacillus (shape)
A bacillus (), also called a bacilliform bacterium or often just a rod (when the context makes the sense clear), is a rod-shaped bacterium or archaeon. Bacilli are found in many different taxonomic groups of bacteria. However, the name ''Bacillus'', capitalized and italicized, refers to a specific genus of bacteria. The name Bacilli, capitalized but not italicized, can also refer to a less specific taxonomic group of bacteria that includes two orders, one of which contains the genus ''Bacillus''. When the word is formatted with lowercase and not italicized, 'bacillus', it will most likely be referring to shape and not to the genus at all. Bacilliform bacteria are also often simply called rods when the bacteriologic context is clear. Bacilli usually divide in the same plane and are solitary, but can combine to form diplobacilli, streptobacilli, and palisades. * Diplobacilli: Two bacilli arranged side by side with each other. * Streptobacilli: Bacilli arranged in chains. * Coccobac ...
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Veillonella Parvula
''Veillonella parvula'' is a strictly anaerobic, Gram-negative, coccus-shaped bacterium in the genus ''Veillonella''. It is a normal part of the oral flora but can be associated with diseases such as periodontitis and dental caries as well as various systemic infections, including meningitis and osteomyelitis. It has also been isolated from women with bacterial vaginosis and has been associated with hypertension together with ''Campylobacter rectus'' and ''Prevotella melaninogenica''. ''V. parvula'' is unable to feed on carbohydrates, but can feed on lactate provided by ''Streptococcus'' species also found in the oral cavity. Specifically, ''Streptococcus mutans'' and ''V. parvula'' can form multispecies biofilms that lead to a lower susceptibility to antimicrobial treatments, resulting in periodontitis and dental carries. Antimicrobial susceptibility ''V. parvula'' bacteria are susceptible to and typically treated with metronidazole and penicillin in clinical reports. Other an ...
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Campylobacter Rectus
''Campylobacter rectus'' is a species of '' Campylobacter''. It is implicated as a pathogen in chronic periodontitis, which can induce bone loss. This motile bacillus is a Gram negative, facultative anaerobe. ''C. rectus'' is associated with hypertension together with ''Prevotella melaninogenica'' and ''Veillonella parvula ''Veillonella parvula'' is a strictly anaerobic, Gram-negative, coccus-shaped bacterium in the genus ''Veillonella''. It is a normal part of the oral flora but can be associated with diseases such as periodontitis and dental caries as well as var ...''. References Further reading * External linksType strain of ''Campylobacter rectus'' at Bac''Dive'' - the Bacterial Diversity Metadatabase Campylobacterota Bacteria described in 1991 {{Campylobacterota-stub ...
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Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high blood pressure, however, is a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. Hypertension is a major cause of premature death worldwide. High blood pressure is classified as primary (essential) hypertension or secondary hypertension. About 90–95% of cases are primary, defined as high blood pressure due to nonspecific lifestyle and genetic factors. Lifestyle factors that increase the risk include excess salt in the diet, excess body weight, smoking, and alcohol use. The remaining 5–10% of cases are categorized as secondary high blood pressure, defined as high blood pressure due to an identifiable cause, such ...
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Anaerobic Bacteria
An anaerobic organism or anaerobe is any organism that does not require molecular oxygen for growth. It may react negatively or even die if free oxygen is present. In contrast, an aerobic organism (aerobe) is an organism that requires an oxygenated environment. Anaerobes may be unicellular (e.g. protozoans, bacteria) or multicellular. Most fungi are obligate aerobes, requiring oxygen to survive. However, some species, such as the Chytridiomycota that reside in the rumen of cattle, are obligate anaerobes; for these species, anaerobic respiration is used because oxygen will disrupt their metabolism or kill them. Deep waters of the ocean are a common anoxic environment. First observation In his letter of 14 June 1680 to The Royal Society, Antonie van Leeuwenhoek described an experiment he carried out by filling two identical glass tubes about halfway with crushed pepper powder, to which some clean rain water was added. Van Leeuwenhoek sealed one of the glass tubes using a flame and ...
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Bacteroidota
The phylum Bacteroidota (synonym Bacteroidetes) is composed of three large classes of Gram-negative, nonsporeforming, anaerobic or aerobic, and rod-shaped bacteria that are widely distributed in the environment, including in soil, sediments, and sea water, as well as in the guts and on the skin of animals. Although some ''Bacteroides'' spp. can be opportunistic pathogens, many ''Bacteroidota'' are symbiotic species highly adjusted to the gastrointestinal tract. ''Bacteroides'' are highly abundant in intestines, reaching up to 1011 cells g−1 of intestinal material. They perform metabolic conversions that are essential for the host, such as degradation of proteins or complex sugar polymers. ''Bacteroidota'' colonize the gastrointestinal tract already in infants, as non-digestible oligosaccharides in mother milk support the growth of both ''Bacteroides'' and ''Bifidobacterium'' spp. ''Bacteroides'' spp. are selectively recognized by the immune system of the host through specific ...
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Anaerobic Infection
Anaerobic infections are caused by anaerobic bacteria. Obligately anaerobic bacteria do not grow on solid media in room air (0.04% carbon dioxide and 21% oxygen); facultatively anaerobic bacteria can grow in the presence or absence of air. Microaerophilic bacteria do not grow at all aerobically or grow poorly, but grow better under 10% carbon dioxide or anaerobically. Anaerobic bacteria can be divided into strict anaerobes that can not grow in the presence of more than 0.5% oxygen and moderate anaerobic bacteria that are able of growing between 2 and 8% oxygen.Jousimies-Somer HR, Summanen P, Baron EJ, Citron DM, Wexler HM, Finegold SM. Wadsworth-KTL anaerobic bacteriology manual. 6th ed. Belmont, CA: Star Publishing, 2002. Anaerobic bacteria usually do not possess catalase, but some can generate superoxide dismutase which protects them from oxygen. The clinically important anaerobes in decreasing frequency are:Brook, I.: "Anaerobic Infections Diagnosis and Management". A Textbook. ...
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