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Pongine Gammaherpesvirus 2
''Pongine gammaherpesvirus 2'' (PoHV-2), commonly known as orangutan herpesvirus, is a species of virus in the genus ''Lymphocryptovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. It infects orangutans (''Pongo''). References External links * Gammaherpesvirinae {{Virus-stub ...
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Orangutan
Orangutans are great apes native to the rainforests of Indonesia and Malaysia. They are now found only in parts of Borneo and Sumatra, but during the Pleistocene they ranged throughout Southeast Asia and South China. Classified in the genus ''Pongo'', orangutans were originally considered to be one species. From 1996, they were divided into two species: the Bornean orangutan (''P. pygmaeus'', with three subspecies) and the Sumatran orangutan (''P. abelii''). A third species, the Tapanuli orangutan (''P. tapanuliensis''), was identified definitively in 2017. The orangutans are the only surviving species of the subfamily Ponginae, which diverged genetically from the other hominids (gorillas, chimpanzees, and humans) between 19.3 and 15.7 million years ago. The most arboreal of the great apes, orangutans spend most of their time in trees. They have proportionally long arms and short legs, and have reddish-brown hair covering their bodies. Adult males weigh about , while female ...
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Lymphocryptovirus
''Lymphocryptovirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Gammaherpesvirinae''. This genus includes the human-infecting ''Human gammaherpesvirus 4'' (Epstein–Barr virus), as well as viruses that infect both Old World monkeys and New World monkeys. Other names for the ''Lymphocryptovirus'' genus include ''Lymphocryptoviridae'' (suffix -''viridae'' implying family rank, although this is not the accepted taxonomy) and gamma-1 herpesviruses. There are nine species in this genus. Diseases associated with this genus include: mononucleosis, Burkitt's lymphoma, and nasopharyngeal carcinoma. Species The genus consists of the following nine species: * ''Callitrichine gammaherpesvirus 3'' * ''Cercopithecine gammaherpesvirus 14'' * ''Gorilline gammaherpesvirus 1'' * ''Human gammaherpesvirus 4'' * ''Macacine gammaherpesvirus 4'' * ''Macacine gammaherpesvirus 10'' * ''Panine gammaherpesvirus 1'' * ''Papiine gammaherpesv ...
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Gammaherpesvirinae
''Gammaherpesvirinae'' is a subfamily of viruses in the order ''Herpesvirales'' and in the family ''Herpesviridae''. Viruses in ''Gammaherpesvirinae'' are distinguished by reproducing at a more variable rate than other subfamilies of ''Herpesviridae''. Mammals serve as natural hosts. There are 43 species in this subfamily, divided among 7 genera with three species unassigned to a genus. Diseases associated with this subfamily include: HHV-4: infectious mononucleosis. HHV-8: Kaposi's sarcoma. Taxonomy Herpesviruses represent a group of double-stranded DNA viruses distributed widely within the animal kingdom. The family ''Herpesviridae'', which contains eight viruses that infect humans, is the most extensively studied group within this order and comprises three subfamilies, namely ''Alphaherpesvirinae'', ''Betaherpesvirinae'' and ''Gammaherpesvirinae''. Within the ''Gammaherpesvirinae'' there are a number of unclassified viruses including ''Cynomys herpesvirus 1'' (CynGHV-1)Nag ...
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Herpesviridae
''Herpesviridae'' is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word ''ἕρπειν'' ( 'to creep'), referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster ( shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established ''Herpesvirus'' as a genus with 23 viruses among four groups. As of 2020, 115 species are recognized, all but one of which are in one of the three subfamilies. Herpesviruses can cause both latent and lytic infections. Nine herpesvirus types are known to primarily infect humans, at least five of which – herpes simplex viruses 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial herpes and genital herpes), varicella zoster virus (or HHV-3; the cause ...
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Herpesvirales
The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans caused by members of this order include cold sores, genital herpes, chickenpox, shingles, and glandular fever. ''Herpesvirales'' is the sole order in the class ''Herviviricetes'', which is the sole class in the phylum ''Peploviricota''. Virology Morphology All members of the order have a virion structure that consists of a DNA core surrounded by an icosahedral capsid composed of 12 pentavalent and 150 hexavalent capsomeres (T = 16). The capsid has a diameter of ~110 nanometers (nm) and is embedded in a proteinaceous matrix called the tegument, which in its turn is enclosed by a glycoprotein-containing lipid envelope with a diameter of about 200 nm. The DNA genome is linear and double stranded, with sizes in the range 125–290 kb ...
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