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Pirbright Institute
The Pirbright Institute (formerly the Institute for Animal Health) is a research institute in Surrey, England, dedicated to the study of infectious diseases of farm animals. It forms part of the UK government's Biotechnology and Biological Sciences Research Council (BBSRC). The institute employs scientists, vets, PhD students and operations staff. History It began in 1914 to test cows for tuberculosis. More buildings were added in 1925. Compton was established by the Agricultural Research Council in 1937. Pirbright became a research institute in 1939 and Compton in 1942. The Houghton Poultry Research Station at Houghton, Cambridgeshire was established in 1948. In 1963 Pirbright became the Animal Virus Research Institute and Compton became the Institute for Research on Animal Diseases. The Neuropathogenesis Unit (NPU) was established in Edinburgh in 1981. This became part of the Roslin Institute in 2007. In 1987, Compton, Houghton and Pirbright became the Institute for Animal H ...
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Research Institute
A research institute, research centre, research center or research organization, is an establishment founded for doing research. Research institutes may specialize in basic research or may be oriented to applied research. Although the term often implies natural science research, there are also many research institutes in the social science as well, especially for sociological and historical research purposes. Famous research institutes In the early medieval period, several astronomical observatories were built in the Islamic world. The first of these was the 9th-century Baghdad observatory built during the time of the Abbasid caliph al-Ma'mun, though the most famous were the 13th-century Maragheh observatory, and the 15th-century Ulugh Beg Observatory. The Kerala School of Astronomy and Mathematics was a school of mathematics and astronomy founded by Madhava of Sangamagrama in Kerala, India. The school flourished between the 14th and 16th centuries and the original discoverie ...
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John Burns Brooksby
John Burns Brooksby (25 December 1914 – 17 December 1998) was a Scottish veterinarian, animal physiologist and veterinary virologist. He was a recognised expert on serology and especially foot-and-mouth disease, and identified and categorised the majority of its known forms. His advice was taken on an international level, and he played a significant role in disease control in Africa and the Middle East. He was responsible for the control of the spread of this disease at international level. Education and career Brooksby attended Hyndland Secondary School in Glasgow and then the Glasgow Veterinary College. He then completed a BSc in Veterinary Science at London University while lecturing in histology at the college. In 1936 he decided on a career in animal physiology and received a grant to study for three years. He studied at three separate centres of excellence on consecutive years: University College, London; McGill University in Montreal in Canada; and the University of Ed ...
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Merial
Boehringer Ingelheim Animal Health is a multinational animal health company, formed in January 2017 when Merial was acquired by Boehringer Ingelheim and merged with Boehringer Ingelheim's existing animal health assets. Overview In August 1997, Merial started as a joint venture between the animal health subsidiaries of Merck & Co. (MSD AgVet) and Sanofi-Aventis (Rhône-Mérieux). Merial became the animal health division of Sanofi, when Sanofi bought out Merck's 50% share of the joint venture. On December 30, 2016 Boehringer Ingelheim completed a swap of their OTC business for Sanofi's animal health business. Merial is now owned by Boehringer Ingelheim and combined with their animal health business, Boehringer Ingelheim Vetmedica, to form Boehringer Ingelheim Animal Health. Merial produces many products and vaccines for domestic pets, farm animals and wildlife. Merial has about 6,900 employees and is present in more than 150 countries in the world. Their sales in 2015 were about ...
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Berkshire
Berkshire ( ; in the 17th century sometimes spelt phonetically as Barkeshire; abbreviated Berks.) is a historic county in South East England. One of the home counties, Berkshire was recognised by Queen Elizabeth II as the Royal County of Berkshire in 1957 because of the presence of Windsor Castle, and letters patent were issued in 1974. Berkshire is a county of historic origin, a ceremonial county and a non-metropolitan county without a county council. The county town is Reading. The River Thames formed the historic northern boundary, from Buscot in the west to Old Windsor in the east. The historic county, therefore, includes territory that is now administered by the Vale of White Horse and parts of South Oxfordshire in Oxfordshire, but excludes Caversham, Slough and five less populous settlements in the east of the Royal Borough of Windsor and Maidenhead. All the changes mentioned, apart from the change to Caversham, took place in 1974. The towns of Abingdon, Didcot, Far ...
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Compton, Berkshire
Compton is a village and civil parish in the River Pang valley in the Berkshire Downs about south of Didcot which is buffered from neighbouring settlements by cultivated fields to all sides. The village is in a gently-sloped dry valley and the fledgling Pang seasonally enters from the north west and discharges in the south east and may be joined at the centre of the village by the Roden from the North, when winter bournes rise to fill their channels. Elevations vary from 95 to 155m AOD. Parish church The bell tower of the Church of England parish church of Saint Mary and Saint Nicholas was built in the 13th centuryPevsner, 1965, page 120 and has Perpendicular Gothic features that were added in the 15th century.Page & Ditchfield, 1925, pages 15-21 In 1850 the nave and chancel were modernised or rebuilt and in 1905 the Gothic Revival architect John Oldrid Scott added the north aisle. Transport Former railway In 1882 the Didcot, Newbury and Southampton Railway was completed thr ...
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ...
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Livestock
Livestock are the domesticated animals raised in an agricultural setting to provide labor and produce diversified products for consumption such as meat, eggs, milk, fur, leather, and wool. The term is sometimes used to refer solely to animals who are raised for consumption, and sometimes used to refer solely to farmed ruminants, such as cattle, sheep, goats and pigs. Horses are considered livestock in the United States. The USDA classifies pork, veal, beef, and lamb (mutton) as livestock, and all livestock as red meat. Poultry and fish are not included in the category. The breeding, maintenance, slaughter and general subjugation of livestock, called '' animal husbandry'', is a part of modern agriculture and has been practiced in many cultures since humanity's transition to farming from hunter-gatherer lifestyles. Animal husbandry practices have varied widely across cultures and time periods. It continues to play a major economic and cultural role in numerous communities. Lives ...
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Animal Virology
Veterinary virology is the study of viruses in non-human animals. It is an important branch of veterinary medicine. Rhabdoviruses Rhabdoviruses are a diverse family of single stranded, negative sense RNA viruses that infect a wide range of hosts, from plants and insects, to fish and mammals. The ''Rhaboviridae'' family consists of six genera, two of which, cytorhabdoviruses and nucleorhabdoviruses, only infect plants. Novirhabdoviruses infect fish, and vesiculovirus, lyssavirus and ephemerovirus infect mammals, fish and invertebrates. The family includes pathogens such as rabies virus, vesicular stomatitis virus and potato yellow dwarf virus that are of public health, veterinary, and agricultural significance. Foot-and-mouth disease virus Foot-and-mouth disease virus (FMDV) is a member of the Aphthovirus genus in the Picornaviridae family and is the cause of foot-and-mouth disease in pigs, cattle, sheep and goats. It is a non-enveloped, positive strand, RNA virus. FMDV is a ...
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Universal Flu Vaccine
A universal flu vaccine is a flu vaccine that is effective against all influenza strains regardless of the virus sub type, antigenic drift or antigenic shift.Sherwood Linda M, Prescott's Microbiology (10th ed.) McGraw-Hill Education , 2017 Hence it should not require modification from year to year. As of 2021 no universal flu vaccine had been approved for general use, several were in development, and one was in clinical trial. Medical uses New vaccines against currently circulating influenza variants are required every year due to the diversity of flu viruses and variable efficacy of vaccines to prevent them. A universal vaccine would eliminate the need to create a vaccine for each year's variants. The efficacy of a vaccine refers to the protection against a broad variety of influenza strains. Events such as antigenic shift have created pandemic strains such as the H1N1 outbreak in 2009. The research required every year to isolate a potential popular viral strain and create a v ...
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Infectious Diseases
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. ''Mycobacterium tuberculosis'' ...
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Bill & Melinda Gates Foundation
The Bill & Melinda Gates Foundation (BMGF), a merging of the William H. Gates Foundation and the Gates Learning Foundation, is an American private foundation founded by Bill Gates and Melinda French Gates. Based in Seattle, Washington, it was launched in 2000 and is reported as of 2020 to be the second largest charitable foundation in the world, holding $49.8 billion in assets. On his 43rd birthday, Bill Gates gave the foundation $1 billion. The primary stated goals of the foundation are to enhance healthcare and reduce extreme poverty across the world, and to expand educational opportunities and access to information technology in the U.S. Key individuals of the foundation include Bill Gates, Melinda French Gates, Warren Buffett, chief executive officer Mark Suzman, and Michael Larson. The BMGF had an endowment of approximately $50 billion . The scale of the foundation and the way it seeks to apply business techniques to giving makes it one of the leaders in venture philanthr ...
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Wellcome Trust
The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of GlaxoSmithKline) to fund research to improve human and animal health. The aim of the Trust is to "support science to solve the urgent health challenges facing everyone." It had a financial endowment of Pound sterling, £29.1 billion in 2020, making it the fourth List of wealthiest charitable foundations, wealthiest charitable foundation in the world. In 2012, the Wellcome Trust was described by the ''Financial Times'' as the United Kingdom's largest provider of non-governmental funding for scientific research, and one of the largest providers in the world. According to their annual report, the Wellcome Trust spent GBP Pound sterling, £1.1Bn on charitable activities across their 2019/2020 financial year. According to the OECD, the Wellcome ...
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