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Pierre De Meyts
Pierre De Meyts (born 1944) is a Belgian physician and biochemist known for his research on fine chemical and kinetic aspects of ligand-receptor interaction, subunit assembly, and specific metabolic (as well as mitogenic) effects of hormones typically causing receptor tyrosine kinase activation such as insulin and insulin-like growth factors (IGFs). He has also studied receptor signalling for other peptide hormones such as growth hormone and relaxin, and key pathophysiological aspects of diabetes mellitus. De Meyts held professorial posts for over three decades at several European and United States institutions and currently is an emeritus professor in the Science Faculty at the Université catholique de Louvain. While living in Denmark (1990-2010) he occupied executive research positions at Novo Nordisk. De Meyts (a.k.a. Chuck) is also known as a science cartoonist. Biography De Meyts was born in Verviers (Belgium) in 1944. He attended high school at the Athénée Royal de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christophe Plantin Prize
The Christophe Plantin Prize (''French: Prix Christoffel Plantin''), is a Belgian civilian prize, intended to reward a Belgian citizen who resides abroad, who has made significant contributions to cultural, artistic or scientific activities. Named after noted printer Christophe Plantin, the prize was created in 1968 on the initiative of: *Dr. Baron Ludo van Bogaert, doctor *Baron Roger Avermaete, writer *Hugo van Kuyck, architect *Maurits Naessens, banker *OJ Van de Perre, industrialist Funded by voluntary contributions, the prize consists of a 10,000 € fund and a medal created by Antwerp artist May Néama May Néama (Vienna, 1917 – Antwerp, 2007) was an Antwerp artist. She was most known as a painter, illustrator, sculptor and graphic artist. She designed posters, decorations for the interior, illustrations for children’s book, stage sets and .... On one side the medal has a portrait of Christoffel Plantin, accompanied by his statement: ''"I have more hope in po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Relaxin
Relaxin is a protein hormone of about 6000 Da first described in 1926 by Frederick Hisaw. The relaxin family peptide hormones belong to the insulin superfamily and consists of seven peptides of high structural but low sequence similarity; relaxin-1 (RLN1), 2 (RLN2) and 3 (RLN3), and the insulin-like (INSL) peptides, INSL3, INSL4, INSL5 and INSL6. The functions of relaxin-3, INSL4, INSL5, and INSL6 remain uncharacterised. Synthesis In the female, relaxin is produced by the corpus luteum of the ovary, the breast and, during pregnancy, also by the placenta, chorion, and decidua. In the male, it is produced in the prostate and is present in human semen. Structure Structurally, relaxin is a heterodimer of two peptide chains of 24 and 29 amino acids linked by disulfide bridges, and it appears related to insulin. Relaxin is produced from its prohormone, "prorelaxin", by post-translational proteolytic cleavage of its signal peptide and C domain peptide. Function in Humans Re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Duarte, California
Duarte () is a city in Los Angeles County, California, United States. As of the 2020 census, the city population was 21,727. It is bounded to the north by the San Gabriel Mountains, to the north and west by the cities of Bradbury and Monrovia, to the south by the city of Irwindale, and to the east by the cities of Irwindale and Azusa. Duarte is located on historic U.S. Route 66 which today follows Huntington Drive through the middle of the city. The town is named after Andrés Avelino Duarte, a Californio ranchero who founded the community. History Around 500 B.C., a band of Shoshonean-speaking Indians established settlements in what is now the San Gabriel Valley. These Native Americans came to be called the Gabrieliño Indians (after San Gabriel, the local mission) by early Spanish explorers, but now prefer to be called the Tongva. Since the San Gabriel Valley area was home to large numbers of oak trees such as coast live oak and interior live oak, a staple of the Ton ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insulin Receptor
The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase. Metabolically, the insulin receptor plays a key role in the regulation of glucose homeostasis, a functional process that under degenerate conditions may result in a range of clinical manifestations including diabetes and cancer. Insulin signalling controls access to blood glucose in body cells. When insulin falls, especially in those with high insulin sensitivity, body cells begin only to have access to lipids that do not require transport across the membrane. So, in this way, insulin is the key regulator of fat metabolism as well. Biochemically, the insulin receptor is encoded by a single gene , from which alternate splicing during transcription results in either IR-A or IR-B isoforms. Downstream post-translational events of either isoform result in the formation of a proteolytically cleaved α and β subunit, which upon com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Liège
The University of Liège (french: Université de Liège), or ULiège, is a major public university of the French Community of Belgium based in Liège, Wallonia, Belgium. Its official language is French. As of 2020, ULiège is ranked in the 301–350 category worldwide according to ''Times Higher Education'', 451st by ''QS World University Rankings'', and between the 201st and 300th place by the '' Academic Ranking of World Universities''. More than 2,000 people, including academics, scientists and technicians, are involved in research of a wide variety of subjects from basic research to applied research. History The university was founded in 1817 by William I of the Netherlands, then King of the United Kingdom of the Netherlands, and by his Minister of Education, Anton Reinhard Falck. The foundation of the university was the result of a long intellectual tradition which dates back to the origins of the Prince-Bishopric of Liège. Beginning in the eleventh century, the influenc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
High School
A secondary school describes an institution that provides secondary education and also usually includes the building where this takes place. Some secondary schools provide both '' lower secondary education'' (ages 11 to 14) and ''upper secondary education'' (ages 14 to 18), i.e., both levels 2 and 3 of the ISCED scale, but these can also be provided in separate schools. In the US, the secondary education system has separate middle schools and high schools. In the UK, most state schools and privately-funded schools accommodate pupils between the ages of 11–16 or 11–18; some UK private schools, i.e. public schools, admit pupils between the ages of 13 and 18. Secondary schools follow on from primary schools and prepare for vocational or tertiary education. Attendance is usually compulsory for students until age 16. The organisations, buildings, and terminology are more or less unique in each country. Levels of education In the ISCED 2011 education scale levels 2 and 3 c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Verviers
Verviers (; wa, Vervî) is a city and municipality of Wallonia located in the province of Liège, Belgium. The municipality consists of the following districts: Ensival, Heusy, Lambermont, Petit-Rechain, Stembert, and Verviers. It is also the center of an agglomeration that includes Dison and Pepinster, making it the second biggest in the province and an important regional center, located roughly halfway between Liège and the German border. Water has played an important role in the town's economy, notably in the development first of its textile and later its tourist industries. As a result, many fountains have been built in Verviers, leading it to be named Wallonia's "Water Capital". The seats of the two Walloon public institutions for water distribution and water treatment are located in the town. History Early history Various flint and bone fragments, as well as Roman coins, were found in this area, attesting to the early settlements in the region. In the 4th century ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cartoonist
A cartoonist is a visual artist who specializes in both drawing and writing cartoons (individual images) or comics (sequential images). Cartoonists differ from comics writers or comic book illustrators in that they produce both the literary and graphic components of the work as part of their practice. Cartoonists may work in a variety of formats, including booklets, comic strips, comic books, editorial cartoons, graphic novels, User guide, manuals, gag cartoons, storyboards, posters, shirts, books, advertisements, greeting cards, magazines, newspapers, webcomics, and video game packaging. Terminology Cartoonists may also be denoted by terms such as comics artist, comic book artist, graphic novel artist or graphic novelist. Ambiguity may arise because "comic book artist" may also refer to the person who only illustrates the comic, and "graphic novelist" may also refer to the person who only writes the script. History The English satire, satirist and editorial cartoonist Willi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novo Nordisk
Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd, Denmark, with production facilities in nine countries, and affiliates or offices in five countries. Novo Nordisk is controlled by majority shareholder Novo Holdings A/S which holds approximately 25% of its shares and a supermajority (45%) of its voting shares. Novo Nordisk manufactures and markets pharmaceutical products and services specifically diabetes care medications and devices. Novo Nordisk is also involved with hemostasis management, growth hormone therapy and hormone replacement therapy. The company makes several drugs under various brand names, including Levemir, Tresiba, NovoLog, Novolin R, NovoSeven, NovoEight and Victoza. Novo Nordisk employs more than 48,000 people globally, and markets its products in 168 countries. The corporation was created in 1989 through a merger of two Danish companies which date back to the 1920s. The Novo Nordisk logo is the Apis bull, one of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gentofte Municipality
Gentofte Kommune is a municipality (Danish, '' kommune'') in the Capital Region of Denmark (''Region Hovedstaden'') on the east coast of the island of Zealand (''Sjælland'') in eastern Denmark. It covers an area of , and has a total population of 74,548 (1 April 2014). Since 17 May 2021, its mayor has been Michael Fenger, a member of the Conservative People's Party (''Det Konservative Folkeparti''). Gentofte is the most wealthy municipality in Denmark and consists of several fashionable Copenhagen suburbs such as Hellerup and Charlottenlund. The municipality is an amalgamation of three formerly independent towns, and several other local settlements, all close to one another. The site of its municipal council is in Charlottenlund. The three original towns were Gentofte, Vangede and Ordrup. It later included Tuborg, Skovshoved, Dyssegård, Hellerup, Jægersborg, and Klampenborg. Neighboring municipalities are Lyngby-Taarbæk to the north, Gladsaxe to the west, and Copenhagen t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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