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Picower Institute For Learning And Memory
The Picower Institute for Learning and Memory is, along with the McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, one of the three neuroscience groups at MIT. The institute is focused on studying all aspects of learning and memory; specifically, it has received over US$50 million to study Alzheimer's, schizophrenia and similar diseases. When it was established in 1994, the institute was primarily funded by the Sherman Fairchild Foundation, the RIKEN Brain Science Institute and the National Institute of Mental Health. It was renamed after a $50 million grant by the Picower Foundation in 2002. On July 1, 2009, Professor Li-Huei Tsai became the director of the Picower Institute. The institute was directed by founder and Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Picower Institute-20060913
Jeffry M. Picower (May 5, 1942 – October 25, 2009) was an American investor involved in the Madoff investment scandal. He was the largest beneficiary of Madoff's Ponzi scheme, and his widow agreed to have his estate settle the claims against it by Madoff trustee Irving Picard for $7.2 billion, the largest single forfeiture in American judicial history. Business dealings Picower was born in the Bronx, New York. He was a certified public accountant and lawyer, but made most of his fortune by investing with Madoff. As an accountant at Laventhol & Horwath in the 1980s, Picower set up questionable tax shelters. When the IRS challenged their validity, one of Picower's clients sued him and the firm. The case was settled out of court. In 1983, Picower was rebuked by the U.S. Securities and Exchange Commission for late disclosure of his greater than 5% position in a company involved in a merger. In 1991, Picower and Anthony Cerami established a charity, the Picower Institute for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
McGovern Institute For Brain Research
The McGovern Institute for Brain Research is a research institute within MIT. Its mission is to understand how the brain works and to discover new ways to prevent or treat brain disorders. The institute was founded in 2000 by Patrick McGovern and Lore Harp McGovern with a gift to MIT that is expected to total $350M over 20 years. Role The McGovern Institute conducts research into all aspects of brain function, including perception, cognition and action. It also conducts clinical and translational research on a wide range of brain disorders. The institute's core facilities include the Martinos Imaging Center, which provides neuroimaging technologies for human and animal research, including MRI, EEG and MEG. The McGovern Institute occupies approximately 85,000 sq ft (net) within the MIT Brain and Cognitive Sciences Complex. This building, which was completed in 2005, also houses the Picower Institute for Learning and Memory and the Department of Brain and Cognitive Sciences ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alzheimer's
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of APOE. Other risk factors include a history of head injury, clinical depression, and high blood press ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months (DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. In 2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sherman Fairchild Foundation
The Sherman Fairchild Foundation, founded in 1955, is a charitable foundation of Sherman Fairchild, founder and chairman of the Fairchild Corporations. Sherman Mills Fairchild formed two charitable foundations, the Fairchild Foundation and the Sherman Fairchild Foundation during his lifetime. Upon his death on March 28, 1971, he left the bulk of his estate to his foundations. In 2019, the Sherman Fairchild Foundation annual giving was $35,861,412 and total assets were over $829 million. It is headquartered in Chevy Chase, MD Chevy Chase () is the name of both a town and an unincorporated census-designated place (Chevy Chase (CDP), Maryland) that straddle the northwest border of Washington, D.C. and Montgomery County, Maryland, United States. Several settlements in t .... Bonnie Burke Himmelman is the current president, Dale T. Knobel is a director. The Foundation grants are primarily to higher education, the fine arts, and cultural institutions. Recipients include Caltech, D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RIKEN Brain Science Institute
RIKEN Brain Science Institute (RIKEN-BSI) was established in 1997 as part of RIKEN, focusing on neuroscience research located in Wakō city, Saitama Prefecture in the greater Tokyo area, Japan. In 2018 RIKEN-BSI has been reorganized as RIKEN Center for Brain Science, a new center under RIKEN. Yasushi Miyashita became the first Director of RIKEN-CBS.The current director is Ryoichiro Kageyama (2021-). Overview of RIKEN-BSI Masao Ito, formerly a professor at the Faculty of Medicine of Tokyo University, joined RIKEN as the second director of the (former) International Frontier System and initiated the neuroscience research in RIKEN in 1989 after his retirement. It was first major move towards biological science in RIKEN, which had been dominated by physics and chemistry. In 1997, it was expanded to become BSI and Ito became the first director. Subsequently, it was led by the second director, Shun'ichi Amari and interim director Keiji Tanaka, and then currently by 1987 Nobel lau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute Of Mental Health
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. NIMH is the largest research organization in the world specializing in mental illness. Joshua A. Gordon is the current director of NIMH. The institute was first authorized by the U.S. government in 1946, when then President Harry Truman signed into law the National Mental Health Act, although the institute was not formally established until 1949. NIMH is a $1.5 billion enterprise, supporting research on mental health through grants to investigators at institutions and organizations throughout the United States and through its own internal (intramural) research effort. The mission of NIMH is "to transform the understanding and treatment of m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jeffry Picower
Jeffry M. Picower (May 5, 1942 – October 25, 2009) was an American investor involved in the Madoff investment scandal. He was the largest beneficiary of Madoff's Ponzi scheme, and his widow agreed to have his estate settle the claims against it by Madoff trustee Irving Picard for $7.2 billion, the largest single forfeiture in American judicial history. Business dealings Picower was born in the Bronx, New York. He was a certified public accountant and lawyer, but made most of his fortune by investing with Madoff. As an accountant at Laventhol & Horwath in the 1980s, Picower set up questionable tax shelters. When the IRS challenged their validity, one of Picower's clients sued him and the firm. The case was settled out of court. In 1983, Picower was rebuked by the U.S. Securities and Exchange Commission for late disclosure of his greater than 5% position in a company involved in a merger. In 1991, Picower and Anthony Cerami established a charity, the Picower Institute for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Li-Huei Tsai
Li-Huei Tsai () is a neuroscientist and the director of the Picower Institute for Learning and Memory in the Department of Brain and Cognitive Sciences at the Massachusetts Institute of Technology. She is known for her work on neurological disorders that affect learning and memory, particularly for her research on Alzheimer’s disease and the role of CDK5 and chromatin remodeling in the progression of the disease. Additionally, her laboratory has innovated numerous applications of induced pluripotent stem cells for ''in vitro'' modeling of neurological diseases. Education and career Tsai was born and raised in Taiwan. In 1984, she received a fellowship to pursue a master's degree in veterinary medicine at the University of Wisconsin-Madison. After attending a series of lectures delivered by Nobel Prize laureate and cancer researcher Howard Temin, she developed an interest in molecular cancer research. Tsai earned her PhD in 1990 from the University of Texas Southwestern Medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Economi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
