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Philip Edward Smith
Philip Edward Smith (January 1, 1884 – December 8, 1970) was an American endocrinologist who is best known for his work studying the pituitary gland. He developed methods for removing pituitary glands from tadpoles and rats and showed that such removal resulted in cessation of growth, and atrophy of other endocrine glands such as the adrenal cortex and the reproductive organs. After graduating with a PhD in Anatomy from Cornell University in 1912, he joined the Department of Anatomy, Berkeley California until 1926. From 1927 to 1952 he served as Professor of Anatomy at the College of Physicians and Surgeons at Columbia University. He became a research associate at Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ..., where he published his last paper in 1963.Med ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
De Smet, South Dakota
De Smet is a city in and the county seat of Kingsbury County, South Dakota, United States. The population was 1,089 at the 2010 census. History Located in the area of South Dakota known as "East River" (east of the Missouri River, which diagonally divides the state), De Smet was platted by European Americans in 1880. It was named for Belgian Father Pierre De Smet, a 19th-century Jesuit missionary who worked with Native Americans in the United States and its territories for most of his life. In the mid 1880s, prairie fires and failures of crops after a three-year period of drought caused many settlers to relocate their farms and homesteads to easier areas. By 1917, De Smet was a cow town, with many trains passing through every day carrying cattle to market. The Charles Ingalls family, originally of Wisconsin, arrived in De Smet in 1879. Their travels and pioneer life in Minnesota, Kansas, Dakota Territory, and Iowa would be later chronicled in the '' Little House'' series of b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atrophy
Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include mutations (which can destroy the gene to build up the organ), poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, excessive amount of apoptosis of cells, and disuse or lack of exercise or disease intrinsic to the tissue itself. In medical practice, hormonal and nerve inputs that maintain an organ or body part are said to have ''trophic'' effects. A diminished muscular trophic condition is designated as ''atrophy''. Atrophy is reduction in size of cell, organ or tissue, after attaining its normal mature growth. In contrast, hypoplasia is the reduction in the cellular numbers of an organ, or tissue that has not attained normal maturity. Atrophy is the general physiological process of reabsorption and breakdown of tissues, involving apoptosis. When it occurs as a result of disease or loss of trophic support because of other diseases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornell University Faculty
Cornell University is a Private Ivy League university, private Statutory college, statutory Land-grant university, land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach and make contributions in all fields of knowledge—from the classics to the sciences, and from the theoretical to the applied. These ideals, unconventional for the time, are captured in Cornell's founding principle, a popular 1868 quotation from founder Ezra Cornell: "I would found an institution where any person can find instruction in any study." Cornell is ranked among the top global universities. The university is organized into seven Undergraduate education, undergraduate colleges and seven graduate school, graduate divisions at its main Ithaca campus, with each college and division defining its specific admission standards and academic programs in near autonomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornell University Alumni
Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach and make contributions in all fields of knowledge—from the classics to the sciences, and from the theoretical to the applied. These ideals, unconventional for the time, are captured in Cornell's founding principle, a popular 1868 quotation from founder Ezra Cornell: "I would found an institution where any person can find instruction in any study." Cornell is ranked among the top global universities. The university is organized into seven undergraduate colleges and seven graduate divisions at its main Ithaca campus, with each college and division defining its specific admission standards and academic programs in near autonomy. The university also administers three satellite campuses, two in New York City and one in Education City, Qatar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Endocrinologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1970 Deaths
Year 197 ( CXCVII) was a common year starting on Saturday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Magius and Rufinus (or, less frequently, year 950 '' Ab urbe condita''). The denomination 197 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * February 19 – Battle of Lugdunum: Emperor Septimius Severus defeats the self-proclaimed emperor Clodius Albinus at Lugdunum (modern Lyon). Albinus commits suicide; legionaries sack the town. * Septimius Severus returns to Rome and has about 30 of Albinus's supporters in the Senate executed. After his victory he declares himself the adopted son of the late Marcus Aurelius. * Septimius Severus forms new naval units, manning all the triremes in Italy with heavily armed troops for war in the East. His soldiers embark ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1884 Births
Events January–March * January 4 – The Fabian Society is founded in London. * January 5 – Gilbert and Sullivan's ''Princess Ida'' premières at the Savoy Theatre, London. * January 18 – Dr. William Price attempts to cremate his dead baby son, Iesu Grist, in Wales. Later tried and acquitted on the grounds that cremation is not contrary to English law, he is thus able to carry out the ceremony (the first in the United Kingdom in modern times) on March 14, setting a legal precedent. * February 1 – ''A New English Dictionary on historical principles, part 1'' (edited by James A. H. Murray), the first fascicle of what will become ''The Oxford English Dictionary'', is published in England. * February 5 – Derby County Football Club is founded in England. * March 13 – The siege of Khartoum, Sudan, begins (ends on January 26, 1885). * March 28 – Prince Leopold, the youngest son and the eighth child of Queen Victoria and Pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asimov's Biographical Encyclopedia Of Science And Technology
''Asimov's Biographical Encyclopedia of Science and Technology'' is a history of science by Isaac Asimov, written as the biographies of initially 1000 scientists and later with over 1500 entries. Organized chronologically, beginning with Imhotep (entry " ) and concluding with Stephen Hawking (entry "510), each biographical entry is numbered, allowing for easy cross-referencing of one scientist with another. Nearly every biographical sketch contains links to other biographies. For example, the article about John Franklin Enders 195has the sentence "Alexander Fleming's 077penicillin was available thanks to the work of Howard Florey 213and Ernst Boris Chain 306 . . ." This allows one to quickly refer to the articles about Fleming, Florey, and Chain. It includes scientists in all fields including biologists, chemists, astronomers, physicists, mathematicians, geologist, and explorers. The alphabetical list of biographical entries starts with ABBE, Cleveland 38and ends with ZWOR ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenal Cortex
The adrenal cortex is the outer region and also the largest part of an adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis. – "Adrenal Gland" Layers The adrenal cortex comprises three main zones, or layers that are regulated by distinct hormones as noted below. This ''anatomic zonation'' can be appreciated at the microscopic level, where each zone can be recognized and distinguished from one another based on structural and anatomic characteristics. ;Zona glomerulosa :The outermost layer, the zona glomerulosa is the main site for the production of aldosterone, a mineralocorticoid. The synthesis and secretion of aldosterone are mainly regulated by the renin–angiotensin–aldosterone system. The zona glomerulosa cells express a specific enzyme aldosterone synthase (also known as CYP11B2). Aldosterone is largel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrine Gland
Endocrine glands are ductless glands of the endocrine system that secrete their products, hormones, directly into the blood. The major glands of the endocrine system include the pineal gland, pituitary gland, pancreas, ovaries, testes, thyroid gland, parathyroid gland, hypothalamus and adrenal glands. The hypothalamus and pituitary glands are neuroendocrine organs. Pituitary gland The pituitary gland hangs from the base of the brain by the pituitary stalk, and is enclosed by bone. It consists of a hormone-producing glandular portion of the anterior pituitary and a neural portion of the posterior pituitary, which is an extension of the hypothalamus. The hypothalamus regulates the hormonal output of the anterior pituitary and creates two hormones that it exports to the posterior pituitary for storage and later release. Four of the six anterior pituitary hormones are tropic hormones that regulate the function of other endocrine organs. Most anterior pituitary hormones exhibit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pituitary Gland
In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The hypophysis rests upon the hypophyseal fossa of the sphenoid bone in the center of the middle cranial fossa and is surrounded by a small bony cavity (sella turcica) covered by a dural fold (diaphragma sellae). The anterior pituitary (or adenohypophysis) is a lobe of the gland that regulates several physiological processes including stress, growth, reproduction, and lactation. The intermediate lobe synthesizes and secretes melanocyte-stimulating hormone. The posterior pituitary (or neurohypophysis) is a lobe of the gland that is functionally connected to the hypothalamus by the median eminence via a small tube called the pituitary stalk (also called the infundibular stalk or the infundibulum). Hormones secreted from the pituitary gland ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
South Dakota
South Dakota (; Sioux language, Sioux: , ) is a U.S. state in the West North Central states, North Central region of the United States. It is also part of the Great Plains. South Dakota is named after the Lakota people, Lakota and Dakota people, Dakota Sioux Native Americans in the United States, Native American tribes, who comprise a large portion of the population with nine Indian reservation, reservations currently in the state and have historically dominated the territory. South Dakota is the List of U.S. states and territories by area, seventeenth largest by area, but the List of U.S. states and territories by population, 5th least populous, and the List of U.S. states and territories by population density, 5th least densely populated of the List of U.S. states, 50 United States. As the southern part of the former Dakota Territory, South Dakota became a state on November 2, 1889, simultaneously with North Dakota. They are the 39th and 40th states admitted to the union; Pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
