Paul Kaznelson
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Paul Kaznelson
Paul Kaznelson (1898–1959) was a Polish-born Czech scientist credited with describing the first case of pure red cell aplasia. He is also known for his contribution to the discovery of the therapeutic role of splenectomy in idiopathic thrombocytopenic purpura. Much of his academic work appeared in the 1920s and 1930s, when he used to work at the Charles University in Prague. See also * Hermann Schloffer Hermann Schloffer (May 13, 1868 in Graz - January 21, 1937) was an Austrian surgeon. He studied medicine at the University of Freiburg and University of Graz, where in 1892 he earned his medical doctorate. He spent several years in Prague as a su ... References * Sources *Ludmila Hlaváčková – Petr Svobodný, Biographisches Lexikon der Deutschen medizinischen Fakultät in Prag 1883–1945, Prague: Karolinum publishing house, 1998, p. 107. . Czech scientists Scientists from Warsaw 19th-century Polish Jews 1898 births 1959 deaths Date of death ...
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Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ...
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Splenectomy
A splenectomy is the surgical procedure that partially or completely removes the spleen. The spleen is an important organ in regard to immunological function due to its ability to efficiently destroy encapsulated bacteria. Therefore, removal of the spleen runs the risk of overwhelming post-splenectomy infection, a medical emergency and rapidly fatal disease caused by the inability of the body's immune system to properly fight infection following splenectomy or asplenia. Common indications for splenectomy include trauma, tumors, splenomegaly or for hematological disease such as sickle cell anemia or thalassemia. Indications The spleen is an organ located in the abdomen next to the stomach. It is composed of red pulp which filters the blood, removing foreign material, damaged and worn out red blood cells. It also functions as a storage site for iron, red blood cells and platelets. The rest (~25%) of the spleen is known as the white pulp and functions like a large lymph node bein ...
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Date Of Death Missing
Date or dates may refer to: *Date (fruit), the fruit of the date palm (''Phoenix dactylifera'') Social activity *Dating, a form of courtship involving social activity, with the aim of assessing a potential partner **Group dating *Play date, an appointment for children to get together for a few hours * Meeting, when two or more people come together Chronology * Calendar date, a day on a calendar ** Old Style and New Style dates, from before and after the change from the Julian calendar to the Gregorian calendar ** ISO 8601, an international standard covering date formats *Date (metadata), a representation term to specify a calendar date **DATE command, a system time command for displaying the current date *Chronological dating, attributing to an object or event a date in the past **Radiometric dating, dating materials such as rocks in which trace radioactive impurities were incorporated when they were formed Arts, entertainment and media Music *Date (band), a Swedish dans ...
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1959 Deaths
Events January * January 1 - Cuba: Fulgencio Batista flees Havana when the forces of Fidel Castro advance. * January 2 - Lunar probe Luna 1 was the first man-made object to attain escape velocity from Earth. It reached the vicinity of Earth's Moon, and was also the first spacecraft to be placed in heliocentric orbit. * January 3 ** The three southernmost atolls of the Maldive Islands, Maldive archipelago (Addu Atoll, Huvadhu Atoll and Fuvahmulah island) United Suvadive Republic, declare independence. ** Alaska is admitted as the 49th U.S. state. * January 4 ** In Cuba, rebel troops led by Che Guevara and Camilo Cienfuegos enter the city of Havana. ** Léopoldville riots: At least 49 people are killed during clashes between the police and participants of a meeting of the ABAKO Party in Kinshasa, Léopoldville in the Belgian Congo. * January 6 ** Fidel Castro arrives in Havana. ** The International Maritime Organization is inaugurated. * January 7 – The United States reco ...
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1898 Births
Events January–March * January 1 – New York City annexes land from surrounding counties, creating the City of Greater New York as the world's second largest. The city is geographically divided into five boroughs: Manhattan, Brooklyn, Queens, The Bronx and Staten Island. * January 13 – Novelist Émile Zola's open letter to the President of the French Republic on the Dreyfus affair, ''J'Accuse…!'', is published on the front page of the Paris daily newspaper ''L'Aurore'', accusing the government of wrongfully imprisoning Alfred Dreyfus and of antisemitism. * February 12 – The automobile belonging to Henry Lindfield of Brighton rolls out of control down a hill in Purley, London, England, and hits a tree; thus he becomes the world's first fatality from an automobile accident on a public highway. * February 15 – Spanish–American War: The USS ''Maine'' explodes and sinks in Havana Harbor, Cuba, for reasons never fully established, killing 266 ...
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19th-century Polish Jews
The 19th (nineteenth) century began on 1 January 1801 ( MDCCCI), and ended on 31 December 1900 ( MCM). The 19th century was the ninth century of the 2nd millennium. The 19th century was characterized by vast social upheaval. Slavery was abolished in much of Europe and the Americas. The First Industrial Revolution, though it began in the late 18th century, expanding beyond its British homeland for the first time during this century, particularly remaking the economies and societies of the Low Countries, the Rhineland, Northern Italy, and the Northeastern United States. A few decades later, the Second Industrial Revolution led to ever more massive urbanization and much higher levels of productivity, profit, and prosperity, a pattern that continued into the 20th century. The Islamic gunpowder empires fell into decline and European imperialism brought much of South Asia, Southeast Asia, and almost all of Africa under colonial rule. It was also marked by the collapse of the large S ...
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Scientists From Warsaw
A scientist is a person who conducts scientific research to advance knowledge in an area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales (circa 624-545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. In modern times, many scientists have advanced degrees in an area of science and pursue careers in various sectors of the economy such as academia, industry, government, and nonprofit environments.'''' History The roles ...
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Czech Scientists
Czech may refer to: * Anything from or related to the Czech Republic, a country in Europe ** Czech language ** Czechs, the people of the area ** Czech culture ** Czech cuisine * One of three mythical brothers, Lech, Czech, and Rus' Places *Czech, Łódź Voivodeship, Poland *Czechville, Wisconsin, unincorporated community, United States People * Bronisław Czech (1908–1944), Polish sportsman and artist * Danuta Czech (1922–2004), Polish Holocaust historian * Hermann Czech (born 1936), Austrian architect * Mirosław Czech (born 1968), Polish politician and journalist of Ukrainian origin * Zbigniew Czech (born 1970), Polish diplomat See also * Čech, a surname * Czech lands * Czechoslovakia * List of Czechs * * * Czechoslovak (other) * Czech Republic (other) * Czechia (other) Czechia is the official short form name of the Czech Republic. Czechia may also refer to: * Historical Czech lands *Czechoslovakia (1918–1993) *Czech Socialist Repu ...
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Hermann Schloffer
Hermann Schloffer (May 13, 1868 in Graz - January 21, 1937) was an Austrian surgeon. He studied medicine at the University of Freiburg and University of Graz, where in 1892 he earned his medical doctorate. He spent several years in Prague as a surgical assistant and associate professor, and in 1903-1911 was a surgeon and professor at the University of Innsbruck. Afterwards he was a professor at Charles University in Prague. On March 16, 1907 Schloffer performed the first transsphenoidal surgery for removal of a pituitary adenoma at the University of Innsbruck. Unfortunately, the patient died several weeks afterwards from a residual tumor. His name is lent to the eponymous "Schloffer tumor", described as an uncommon pseudo-tumor of the abdominal wall that usually appears several years after abdominal surgery. In 1916 Schloffer became the first to remove a spleen for idiopathic thrombocytopenic purpura (ITP). His student Paul Kaznelson (1898-1959) hypothesized - in analogy with ...
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Prague
Prague ( ; cs, Praha ; german: Prag, ; la, Praga) is the capital and largest city in the Czech Republic, and the historical capital of Bohemia. On the Vltava river, Prague is home to about 1.3 million people. The city has a temperate oceanic climate, with relatively warm summers and chilly winters. Prague is a political, cultural, and economic hub of central Europe, with a rich history and Romanesque, Gothic, Renaissance and Baroque architectures. It was the capital of the Kingdom of Bohemia and residence of several Holy Roman Emperors, most notably Charles IV (r. 1346–1378). It was an important city to the Habsburg monarchy and Austro-Hungarian Empire. The city played major roles in the Bohemian and the Protestant Reformations, the Thirty Years' War and in 20th-century history as the capital of Czechoslovakia between the World Wars and the post-war Communist era. Prague is home to a number of well-known cultural attractions, many of which survived the ...
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Pure Red Cell Aplasia
Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of aplastic anemia affecting the precursors to red blood cells but usually not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. There are multiple etiologies that can cause PRCA. The condition has been first described by Paul Kaznelson in 1922. Signs and symptoms Signs and symptoms may include: * Pale appearance * Rapid heart rate * Fatigue Causes Causes of PRCA include: Treatment PRCA is considered an autoimmune disease as it will respond to immunosuppressant treatment such as cyclosporin in many patients, though this approach is not without risk. It has also been shown to respond to treatments with rituximab and tacrolimus. See also * Diamond–Blackfan anemia (genetic red cell aplasia) * Aplastic anemia Aplastic anemia is a cancer in which the body fails to make blood cells in sufficient numbers. Blood cells are produced in the bone marrow by stem cells that reside ...
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Russian Empire
The Russian Empire was an empire and the final period of the Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended the Great Northern War. The rise of the Russian Empire coincided with the decline of neighbouring rival powers: the Swedish Empire, the Polish–Lithuanian Commonwealth, Qajar Iran, the Ottoman Empire, and Qing China. It also held colonies in North America between 1799 and 1867. Covering an area of approximately , it remains the third-largest empire in history, surpassed only by the British Empire and the Mongol Empire; it ruled over a population of 125.6 million people per the 1897 Russian census, which was the only census carried out during the entire imperial period. Owing to its geographic extent across three continents at its peak, it featured great ethnic, linguistic, religious, and economic diversity. From the 10th–17th centuries, the land ...
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