Paul-Louis Simond
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Paul-Louis Simond
Paul-Louis Simond (30 July 1858 – 3 March 1947) was a French physician, chief medical officer and biologist whose major contribution to science was his demonstration that the intermediates in the transmission of bubonic plague from rats to humans are the fleas '' Xenopsylla cheopis'' that dwell on infected rats. Early life Paul-Louis Simond was born in Beaufort-sur-Gervanne, ( Drome, France) on 30 July 1858. His father was a pastor of the Reformed Church. From 1878 to 1882 Simond was an assistant in Medical and Biological Sciences at the School of Medicine and Pharmacy in Bordeaux, and he began his medical training there. From 1882 to 1886 he served as director of the leprosarium in Acarouany near Saint-Laurent-du-Maroni, French Guiana, where he contracted an attenuated form of yellow fever. He returned to Bordeaux in 1886 and the following year he received his medical doctorate with a prize-winning thesis on leprosy. Career In 1895 he began work at the Pasteur Institute in ...
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Beaufort-sur-Gervanne
Beaufort-sur-Gervanne (; Vivaro-Alpine dialect, Vivaro-Alpine: ''Beufòrt de Gervana'') is a Communes of France, commune in the Drôme Departments of France, department in southeastern France. Population See also *Communes of the Drôme department *Parc naturel régional du Vercors References

Communes of Drôme {{Drôme-geo-stub ...
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Leprosy
Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damage may result in a lack of ability to feel pain, which can lead to the loss of parts of a person's extremities from repeated injuries or infection through unnoticed wounds. An infected person may also experience muscle weakness and poor eyesight. Leprosy symptoms may begin within one year, but, for some people, symptoms may take 20 years or more to occur. Leprosy is spread between people, although extensive contact is necessary. Leprosy has a low pathogenicity, and 95% of people who contract ''M. leprae'' do not develop the disease. Spread is thought to occur through a cough or contact with fluid from the nose of a person infected by leprosy. Genetic factors and immune function play a role in how easily a person catches the disease. Lepro ...
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Pierre Paul Emile Roux
Pierre is a masculine given name. It is a French language, French form of the name Peter (given name), Peter. Pierre originally meant "rock" or "stone" in French (derived from the Greek word πέτρος (''petros'') meaning "stone, rock", via Latin "petra"). It is a translation of Aramaic כיפא (''Kefa),'' the nickname Jesus gave to apostle Saint Peter, Simon Bar-Jona, referred in English as Saint Peter. Pierre is also found as a surname. People with the given name * Abbé Pierre, Henri Marie Joseph Grouès (1912–2007), French Catholic priest who founded the Emmaus Movement * Monsieur Pierre, Pierre Jean Philippe Zurcher-Margolle (c. 1890–1963), French ballroom dancer and dance teacher * Pierre (footballer), Lucas Pierre Santos Oliveira (born 1982), Brazilian footballer * Pierre, Baron of Beauvau (c. 1380–1453) * Pierre, Duke of Penthièvre (1845–1919) * Pierre, marquis de Fayet (died 1737), French naval commander and Governor General of Saint-Domingue * Prince Pier ...
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Yersinia Pestis
''Yersinia pestis'' (''Y. pestis''; formerly '' Pasteurella pestis'') is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both ''Yersinia pseudotuberculosis'' and ''Yersinia enterocolitica''. It is a facultative anaerobic organism that can infect humans via the Oriental rat flea (''Xenopsylla cheopis''). It causes the disease plague, which caused the first plague pandemic and the Black Death, the deadliest pandemic in recorded history. Plague takes three main forms: pneumonic, septicemic, and bubonic. ''Yersinia pestis'' is a parasite of its host, the rat flea, which is also a parasite of rats, hence ''Y. pestis'' is a hyperparasite. ''Y. pestis'' was discovered in 1894 by Alexandre Yersin, a Swiss/French physician and bacteriologist from the Pasteur Institute, during an epidemic of the plague in Hong Kong. Yersin was a member of the Pasteur school of thought. Kitasato Shibasaburō, a Japanese bacteriologist who practised Koch's me ...
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Bacterium
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationshi ...
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Karachi
Karachi (; ur, ; ; ) is the most populous city in Pakistan and 12th most populous city in the world, with a population of over 20 million. It is situated at the southern tip of the country along the Arabian Sea coast. It is the former capital of Pakistan and capital of the province of Sindh. Ranked as a beta-global city, it is Pakistan's premier industrial and financial centre, with an estimated GDP of over $200 billion ( PPP) . Karachi paid $9billion (25% of whole country) as tax during fiscal year July 2021 to May 2022 according to FBR report. Karachi is Pakistan's most cosmopolitan city, linguistically, ethnically, and religiously diverse, as well as one of Pakistan's most secular and socially liberal cities. Karachi serves as a transport hub, and contains Pakistan’s two largest seaports, the Port of Karachi and Port Qasim, as well as Pakistan's busiest airport, Jinnah International Airport. Karachi is also a media center, home to news channels, film and fashi ...
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Antiserum
Antiserum is a blood serum containing monoclonal or polyclonal antibodies that is used to spread passive immunity to many diseases via blood donation (plasmapheresis). For example, convalescent serum, passive antibody transfusion from a previous human survivor, used to be the only known effective treatment for ebola infection with a high success rate of 7 out of 8 patients surviving. Antisera are widely used in diagnostic virology laboratories. The most common use of antiserum in humans is as antitoxin or antivenom to treat envenomation. Serum therapy, also known as serotherapy, describes the treatment of infectious disease using the serum of animals that have been immunized against the specific organisms or their product, to which the disease is supposedly referable. History In 1890, Emil Behring and Kitasato Shibasaburō published their first paper on serum therapy. Behring had pioneered the technique, using guinea pigs to produce serum. Based on his observation that people ...
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Bombay
Mumbai (, ; also known as Bombay — the official name until 1995) is the capital city of the Indian state of Maharashtra and the ''de facto'' financial centre of India. According to the United Nations, as of 2018, Mumbai is the second-most populous city in India after Delhi and the eighth-most populous city in the world with a population of roughly 20 million (2 crore). As per the Indian government population census of 2011, Mumbai was the most populous city in India with an estimated city proper population of 12.5 million (1.25 crore) living under the Brihanmumbai Municipal Corporation. Mumbai is the centre of the Mumbai Metropolitan Region, the sixth most populous metropolitan area in the world with a population of over 23 million (2.3 crore). Mumbai lies on the Konkan coast on the west coast of India and has a deep natural harbour. In 2008, Mumbai was named an alpha world city. It has the highest number of millionaires and billionaires among all cities i ...
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Vietnam
Vietnam or Viet Nam ( vi, Việt Nam, ), officially the Socialist Republic of Vietnam,., group="n" is a country in Southeast Asia, at the eastern edge of mainland Southeast Asia, with an area of and population of 96 million, making it the world's sixteenth-most populous country. Vietnam borders China to the north, and Laos and Cambodia to the west. It shares maritime borders with Thailand through the Gulf of Thailand, and the Philippines, Indonesia, and Malaysia through the South China Sea. Its capital is Hanoi and its largest city is Ho Chi Minh City (commonly known as Saigon). Vietnam was inhabited by the Paleolithic age, with states established in the first millennium BC on the Red River Delta in modern-day northern Vietnam. The Han dynasty annexed Northern and Central Vietnam under Chinese rule from 111 BC, until the first dynasty emerged in 939. Successive monarchical dynasties absorbed Chinese influences through Confucianism and Buddhism, and expanded ...
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Alexandre Yersin
Alexandre Emile Jean Yersin (22 September 1863 – 1 March 1943) was a Swiss- French physician and bacteriologist. He is remembered as the co-discoverer of the bacillus responsible for the bubonic plague or pest, which was later named in his honour: ''Yersinia pestis''. Another bacteriologist, the Japanese physician Kitasato Shibasaburō, is often credited with independently identifying the bacterium a few days earlier, but may have identified a different bacterium and not the pathogen-causing plague. Yersin also demonstrated for the first time that the same bacillus was present in the rodent as well as in the human disease, thus underlining the possible means of transmission. Early life and education Yersin was born in 1863 in Aubonne, in the canton of Vaud, Switzerland, as the posthumous son of Jean-Alexandre-Marc Yersin from his wife Fanny-Isaline-Emilie Moschell. From 1883 to 1884 he studied medicine at Lausanne, followed by Marburg, and Paris (1884–1886). Career In 1 ...
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Coccidia
Coccidia (Coccidiasina) are a subclass of microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida. As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, and are the largest group of apicomplexan protozoa. Infection with these parasites is known as coccidiosis. Coccidia can infect all mammals, some birds, some fish, some reptiles, and some amphibians. Most species of coccidia are species-specific in their host. An exception is ''Toxoplasma gondii'', which can infect all mammals, although it can only undergo sexual reproduction in cats. Depending on the species of coccidia, infection can cause fever, vomiting, diarrhea, muscle pain, and nervous system effects and changes to behavior, and may lead to death. Healthy adults may recover without medication—but those who are immunocompromised or young almost certainly requi ...
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Elie Metchnikoff
Elie and Earlsferry is a coastal town and former royal burgh in Fife, and parish, Scotland, situated within the East Neuk beside Chapel Ness on the north coast of the Firth of Forth, eight miles east of Leven. The burgh comprised the linked villages of Elie ( ) to the east and to the west Earlsferry, which were formally merged in 1930 by the Local Government (Scotland) Act 1929. To the north is the village of Kilconquhar and Kilconquhar Loch. The civil parish has a population of 861 (in 2011).Census of Scotland 2011, Table KS101SC – Usually Resident Population, publ. by National Records of Scotland. Web site http://www.scotlandscensus.gov.uk/ retrieved March 2016. See "Standard Outputs", Table KS101SC, Area type: Civil Parish 1930 Ancient times Earlsferry, the older of the two villages, was first settled in time immemorial . It is said that MacDuff, the Earl of Fife, crossed the Forth here in 1054 while fleeing from King Macbeth. In particular the legend tells of his esca ...
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