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Parieto-frontal Integration Theory
The parieto-frontal integration theory (P-FIT) considers intelligence to relate to how well different brain regions integrate to form intelligent behaviors. The theory proposes that large scale brain networks connect brain regions, including regions within frontal, parietal, temporal, and cingulate cortices, underlie the biological basis of human intelligence. These regions, which overlap significantly with the task-positive network, allow the brain to communicate and exchange information efficiently with one another. Support for this theory is primarily based on neuroimaging evidence, with support from lesion studies. The P-FIT is influential in that it explains the majority of current neuroimaging findings, as well as increasing empirical support for cognition being the result of large-scale brain networks, rather than numerous domain-specific processes or modules.Bressler, S. L., & Menon, V. (2010). Large-scale brain networks in cognition: emerging methods and principles. ''Tre ...
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Brain
A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a vertebrate's body. In a human, the cerebral cortex contains approximately 14–16 billion neurons, and the estimated number of neurons in the cerebellum is 55–70 billion. Each neuron is connected by synapses to several thousand other neurons. These neurons typically communicate with one another by means of long fibers called axons, which carry trains of signal pulses called action potentials to distant parts of the brain or body targeting specific recipient cells. Physiologically, brains exert centralized control over a body's other organs. They act on the rest of the body both by generating patterns of muscle activity and by driving the secretion of chemicals called hormones. This centralized control allows rapid and coordinated respon ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the brain ...
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Microcephalin
Microcephalin (MCPH1) is a gene that is expressed during fetal brain development. Certain mutations in ''MCPH1'', when homozygous, cause primary microcephaly—a severely diminished brain. Hence, it has been assumed that variants have a role in brain development. However, in normal individuals no effect on mental ability or behavior has yet been demonstrated in either this or another similarly studied microcephaly gene, '' ASPM''. However, an association has been established between normal variation in brain structure, as measured with MRI (i.e., primarily '' cortical surface area'' and total brain volume) but only in females, and common genetic variants within both the MCPH1 gene and another similarly studied microcephaly gene, '' CDK5RAP2''. Structure Microcephalin proteins contain the following three domains: * N-terminal BRCT domain * Central microcephalin protein domain () * C-terminal BRCT domain Expression in the brain MCPH1 is expressed in the fetal brain, in the devel ...
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ASPM (gene)
Abnormal spindle-like microcephaly-associated protein, also known as abnormal spindle protein homolog or Asp homolog, is a protein that in humans is encoded by the ''ASPM'' gene. ASPM is located on chromosome 1, band q31 (1q31). The ''ASPM'' gene contains 28 exons and codes for a 3477 amino‐acid‐long protein. The ASPM protein is conserved across species including human, mouse, ''Drosophila'', and ''C. elegans''. Defective forms of the ASPM gene are associated with autosomal recessive primary microcephaly. "ASPM" is an acronym for "Abnormal Spindle-like, Microcephaly-associated", which reflects its being an ortholog to the ''Drosophila melanogaster'' "abnormal spindle" (''asp'') gene. The expressed protein product of the asp gene is essential for normal mitotic spindle function in embryonic neuroblasts and regulation of neurogenesis. A new allele of ASPM arose sometime in the past 14,000 years (mean estimate 5,800 years), during the Holocene, it seems to have swept through muc ...
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Mediation (statistics)
In statistics, a mediation model seeks to identify and explain the mechanism or process that underlies an observed relationship between an independent variable and a dependent variable via the inclusion of a third hypothetical variable, known as a mediator variable (also a mediating variable, intermediary variable, or intervening variable). Rather than a direct causal relationship between the independent variable and the dependent variable, a mediation model proposes that the independent variable influences the mediator variable, which in turn influences the dependent variable. Thus, the mediator variable serves to clarify the nature of the relationship between the independent and dependent variables. Mediation analyses are employed to understand a known relationship by exploring the underlying mechanism or process by which one variable influences another variable through a mediator variable.Cohen, J.; Cohen, P.; West, S. G.; Aiken, L. S. (2003) ''Applied multiple regression/c ...
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Brodmann Area
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. History Brodmann areas were originally defined and numbered by the German anatomist Korbinian Brodmann based on the cytoarchitectural organization of neurons he observed in the cerebral cortex using the Nissl method of cell staining. Brodmann published his maps of cortical areas in humans, monkeys, and other species in 1909, along with many other findings and observations regarding the general cell types and laminar organization of the mammalian cortex. The same Brodmann area number in different species does not necessarily indicate homologous areas. A similar, but more detailed cortical map was published by Constantin von Economo and Georg N. Koskinas in 1925. Present importance Brodmann areas have been discussed, debated, refined, and renamed exhaustively for nearly a century and remain the most wid ...
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Cingulate Cortex
The cingulate cortex is a part of the brain situated in the medial aspect of the cerebral cortex. The cingulate cortex includes the entire cingulate gyrus, which lies immediately above the corpus callosum, and the continuation of this in the cingulate sulcus. The cingulate cortex is usually considered part of the limbic lobe. It receives inputs from the thalamus and the neocortex, and projects to the entorhinal cortex via the cingulum. It is an integral part of the limbic system, which is involved with emotion formation and processing, learning, and memory. The combination of these three functions makes the cingulate gyrus highly influential in linking motivational outcomes to behavior (e.g. a certain action induced a positive emotional response, which results in learning). This role makes the cingulate cortex highly important in disorders such as depression and schizophrenia. It also plays a role in executive function and respiratory control. Etymology The term ''cingul ...
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Intelligence Quotient
An intelligence quotient (IQ) is a total score derived from a set of standardized tests or subtests designed to assess human intelligence. The abbreviation "IQ" was coined by the psychologist William Stern for the German term ''Intelligenzquotient'', his term for a scoring method for intelligence tests at University of Breslau he advocated in a 1912 book. Historically, IQ was a score obtained by dividing a person's mental age score, obtained by administering an intelligence test, by the person's chronological age, both expressed in terms of years and months. The resulting fraction (quotient) was multiplied by 100 to obtain the IQ score. For modern IQ tests, the raw score is transformed to a normal distribution with mean 100 and standard deviation 15. This results in approximately two-thirds of the population scoring between IQ 85 and IQ 115 and about 2.5 percent each above 130 and below 70. Scores from intelligence tests are estimates of intelligence. Unlike, for example, ...
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Correlation And Dependence
In statistics, correlation or dependence is any statistical relationship, whether causal or not, between two random variables or bivariate data. Although in the broadest sense, "correlation" may indicate any type of association, in statistics it usually refers to the degree to which a pair of variables are ''linearly'' related. Familiar examples of dependent phenomena include the correlation between the height of parents and their offspring, and the correlation between the price of a good and the quantity the consumers are willing to purchase, as it is depicted in the so-called demand curve. Correlations are useful because they can indicate a predictive relationship that can be exploited in practice. For example, an electrical utility may produce less power on a mild day based on the correlation between electricity demand and weather. In this example, there is a causal relationship, because extreme weather causes people to use more electricity for heating or cooling. However ...
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Wechsler Adult Intelligence Scale
The Wechsler Adult Intelligence Scale (WAIS) is an IQ test designed to measure intelligence and cognitive ability in adults and older adolescents. The original WAIS (Form I) was published in February 1955 by David Wechsler, as a revision of the Wechsler–Bellevue Intelligence Scale, released in 1939. It is currently in its fourth edition (''WAIS-IV'') released in 2008 by Pearson, and is the most widely used IQ test, for both adults and older adolescents, in the world. History The WAIS is founded on Wechsler's definition of intelligence, which he defined as "... the global capacity of a person to act purposefully, to think rationally, and to deal effectively with his environment." He believed that intelligence was made up of specific elements that could be isolated, defined, and subsequently measured. However, these individual elements were not entirely independent, but were all interrelated. His argument, in other words, is that general intelligence is composed of various speci ...
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Richard J
Richard is a male given name. It originates, via Old French, from Old Frankish and is a compound of the words descending from Proto-Germanic ''*rīk-'' 'ruler, leader, king' and ''*hardu-'' 'strong, brave, hardy', and it therefore means 'strong in rule'. Nicknames include "Richie", "Dick", "Dickon", " Dickie", "Rich", "Rick", "Rico", "Ricky", and more. Richard is a common English, German and French male name. It's also used in many more languages, particularly Germanic, such as Norwegian, Danish, Swedish, Icelandic, and Dutch, as well as other languages including Irish, Scottish, Welsh and Finnish. Richard is cognate with variants of the name in other European languages, such as the Swedish "Rickard", the Catalan "Ricard" and the Italian "Riccardo", among others (see comprehensive variant list below). People named Richard Multiple people with the same name * Richard Andersen (other) * Richard Anderson (other) * Richard Cartwright (other) * Ri ...
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Rex Jung
Rex Eugene Jung is an American psychologist who has researched on the neural basis of human intelligence and creativity. He is an assistant professor at the University of New Mexico, where he is the director of neuropsychological services. Jung is also a practicing psychologist at his private clinic. Education and academic duties Jung obtained a bachelor's degree from the University of Colorado in 1986 and obtained his PhD in clinical psychology from the University of New Mexico in 2001. Jung is a member of the American Psychological Association (division 40, clinical neuropsychology), the International Society of Intelligence Research (ISIR), and Heterodox Academy. Jung sits on the editorial board of ''Intelligence'', '' Frontiers in Psychiatry'' (neuroimaging and stimulation), and ''Public Library of Science'' (PLoS ONE). Research Jung has published more than 100 peer-reviewed papers, most of which deal with intelligence or creativity. In 2007, Richard Haier and Jung publ ...
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