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PVC Superphylum
The PVC superphylum is a superphylum of bacteria named after its three important members, Planctomycetota, Verrucomicrobiota, and Chlamydiota. Cavalier-Smith postulated that the PVC bacteria probably lost or reduced their peptidoglycan cell wall twice. It has been hypothesised that a member of the PVC clade might have been the host cell in the endosymbiotic theory, endosymbiotic event that gave rise to the first proto-eukaryotic cell. Cavalier-Smith calls the same group Planctobacteria and considers it a phylum. However, this is not followed by the larger scientific community. In the Cavalier-Smith bacterial megaclassification, it is within the bacterial Gracilicutes infra-kingdom and comprises the phyla Chlamydiota, Lentisphaerota, Planctomycetota, Verrucomicrobiota. Molecular signatures Planctomycetota, Verrucomicrobiota, and Chlamydiota in the Bacterial phyla, traditional molecular phylogeny view are considered as phyla and also cluster together in the PVC superphylum, along ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chlamydiota
The Chlamydiota (synonym Chlamydiae) are a bacterial phylum and class whose members are remarkably diverse, including pathogens of humans and animals, symbionts of ubiquitous protozoa, and marine sediment forms not yet well understood. All of the Chlamydiota that humans have known about for many decades are obligate intracellular bacteria; in 2020 many additional Chlamydiota were discovered in ocean-floor environments, and it is not yet known whether they all have hosts. Historically it was believed that all Chlamydiota had a peptidoglycan-free cell wall, but studies in the 2010s demonstrated a detectable presence of peptidoglycan, as well as other important proteins. Among the Chlamydiota, all of the ones long known to science grow only by infecting eukaryotic host cells. They are as small as or smaller than many viruses. They are ovoid in shape and stain Gram-negative. They are dependent on replication inside the host cells; thus, some species are termed obligate intracellula ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gracilicutes
Gracilicutes (Latin: ''gracilis'', slender, and ''cutis'', skin, referring to the cell wall) is a clade in bacterial phylogeny. Traditionally gram staining results were most commonly used as a classification tool, consequently until the advent of molecular phylogeny, the Kingdom Monera (as the domains Bacteria and Archaea were known then) was divided into four phyla, * Gracilicutes (gram-negative, it is split in many groups, but some authors still use it in a narrower sense) * Firmacutes ic(gram-positive, subsequently corrected to Firmicutes, today it excludes the Actinomycetota) * Mollicutes (gram variable, later renamed Tenericutes and now Mycoplasmatota, e.g. ''Mycoplasma'') * Mendosicutes (uneven gram stain, "methanogenic bacteria" now known as methanogens and classed as Archaea) This classification system was abandoned in favour of the three-domain system based on molecular phylogeny started by C. Woese. Using hand-drawn schematics rather than standard molecular phylogenet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lentisphaerae
Lentisphaerota is a phylum of bacteria closely related to Chlamydiota and Verrucomicrobiota. It includes two monotypic orders Lentisphaerales and Victivallales. Phylum members can be aerobic or anaerobic and fall under two distinct phenotypes. These phenotypes live within bodies of sea water and were particularly hard to isolate in a pure culture. One phenotype, ''L. marina'', consists of terrestrial gut microbiota from mammals and birds. It was found in the Sea of Japan. The other phenotype (''L. araneosa'') includes marine microorganisms: sequences from fish and coral microbiomes and marine sediment. Phylogeny The phylogeny based on the work of the All-Species Living Tree Project. Taxonomy The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LSPN) and the National Center for Biotechnology Information (NCBI). * Phylum Lentisphaerota Cho et al. 2021 ** Class Oligosphaeria Qiu et al. 2013 *** Order Oligosphaerales Qiu e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RpoB
The ''rpoB'' gene encodes the β subunit of bacterial RNA polymerase and the homologous plastid-encoded RNA polymerase (PEP). It codes for 1342 amino acids in ''E. coli'', making it the second-largest polypeptide in the bacterial cell. It is targeted by the rifamycin family of antibacterials, such as rifampin. Mutations in ''rpoB'' that confer resistance to rifamycins do so by altering the protein's drug-binding residues, thereby reducing affinity for these antibiotics. Some bacteria contain multiple copies of the 16S rRNA gene, which is commonly used as the molecular marker to study phylogeny. In these cases, the single-copy ''rpoB'' gene can be used to study microbial diversity. An inhibitor of transcription in bacteria, tagetitoxin, also inhibits PEP, showing that the complex found in plants is very similar to the homologous enzyme in bacteria. Drug resistance In a bacterium without the proper mutation(s) in ''rpoB'' rifampicin binds to a site near the fork in the β subun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conserved Signature Indels
Conserved signature inserts and deletions (CSIs) in protein sequences provide an important category of molecular markers for understanding phylogenetic relationships. CSIs, brought about by rare genetic changes, provide useful phylogenetic markers that are generally of defined size and they are flanked on both sides by conserved regions to ensure their reliability. While indels can be arbitrary inserts or deletions, CSIs are defined as only those protein indels that are present within conserved regions of the protein. The CSIs that are restricted to a particular clade or group of species, generally provide good phylogenetic markers of common evolutionary descent. Due to the rarity and highly specific nature of such changes, it is less likely that they could arise independently by either convergent or parallel evolution (i.e. homoplasy) and therefore are likely to represent synapomorphy. Other confounding factors such as differences in evolutionary rates at different sites or among ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synapomorphy
In phylogenetics, an apomorphy (or derived trait) is a novel character or character state that has evolved from its ancestral form (or plesiomorphy). A synapomorphy is an apomorphy shared by two or more taxa and is therefore hypothesized to have evolved in their most recent common ancestor. ) In cladistics, synapomorphy implies homology. Examples of apomorphy are the presence of erect gait, fur, the evolution of three middle ear bones, and mammary glands in mammals but not in other vertebrate animals such as amphibians or reptiles, which have retained their ancestral traits of a sprawling gait and lack of fur. Thus, these derived traits are also synapomorphies of mammals in general as they are not shared by other vertebrate animals. Etymology The word —coined by German entomologist Willi Hennig—is derived from the Ancient Greek words (''sún''), meaning "with, together"; (''apó''), meaning "away from"; and (''morphḗ''), meaning "shape, form". Clade analysis T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poribacteria
Poribacteria are a candidate phylum of bacteria originally discovered in the microbiome of marine sponges (''Porifera''). Poribacteria are Gram-negative primarily aerobic mixotrophs with the ability for oxidative phosphorylation, glycolysis, and autotrophic carbon fixation via the Wood – Ljungdahl pathway. Poribacterial heterotrophy is characterised by an enriched set of glycoside hydrolases, uronic acid degradation, as well as several specific sulfatases. This heterotrophic repertoire of poribacteria was suggested to be involved in the degradation of the extracellular sponge host matrix. Genome Single-cell genomics and metagenomic shotgun sequencing approaches reveal a poribacterial genome size range between about 4.2 and 6.5 megabases encoding 4,254 protein-coding genes, of which an unusually high 24% have no homology to known genes. Among the genes of identifiable homology, reconstructed pathways suggest that the poribacterial central metabolism is capable of glycolysis, tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conserved Signature Indel
Conserved signature inserts and deletions (CSIs) in protein sequences provide an important category of molecular markers for understanding phylogenetic relationships. CSIs, brought about by rare genetic changes, provide useful phylogenetic markers that are generally of defined size and they are flanked on both sides by conserved regions to ensure their reliability. While indels can be arbitrary inserts or deletions, CSIs are defined as only those protein indels that are present within conserved regions of the protein. The CSIs that are restricted to a particular clade or group of species, generally provide good phylogenetic markers of common evolutionary descent. Due to the rarity and highly specific nature of such changes, it is less likely that they could arise independently by either convergent or parallel evolution (i.e. homoplasy) and therefore are likely to represent synapomorphy. Other confounding factors such as differences in evolutionary rates at different sites or among ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UniProt
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature. It is maintained by the UniProt consortium, which consists of several European bioinformatics organisations and a foundation from Washington, DC, United States. The UniProt consortium The UniProt consortium comprises the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). EBI, located at the Wellcome Trust Genome Campus in Hinxton, UK, hosts a large resource of bioinformatics databases and services. SIB, located in Geneva, Switzerland, maintains the ExPASy (Expert Protein Analysis System) servers that are a central resource for proteomics tools and databases. PIR, hosted by the National Biomedical Research Foundation (NBRF) at the Geor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candidate Phyla
A candidate division, candidate phylum or candidate division-level is a lineage of prokaryotic organisms for which until recently no cultured representatives have been found, but evidence of the existence of the clade has been obtained by 16S rRNA and metagenomic analysis of environmental samples. The term candidatus in fact means a species for which there is insufficient information to call it a new species according to the International Code of Nomenclature of Bacteria Examples of Candidate division bacteria * Candidate division TM7 (Saccharibacteria) * Poribacteria * TG3 (candidate phylum) (Chitinivibrionia) See also * Metagenomics * Cloning * DNA sequencing DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. Th ... References {{reflist Candidatus taxa Bacteria phyla Archae ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacterial Phyla
Bacterial phyla constitute the major lineages of the domain ''Bacteria''. While the exact definition of a bacterial phylum is debated, a popular definition is that a bacterial phylum is a monophyletic lineage of bacteria whose 16S rRNA genes share a pairwise sequence identity of ~75% or less with those of the members of other bacterial phyla. It has been estimated that ~1,300 bacterial phyla exist. As of May 2020, 41 bacterial phyla are formally accepted by the LPSN, 89 bacterial phyla are recognized on thSilva database dozens more have been proposed, and hundreds likely remain to be discovered. As of 2017, approximately 72% of widely recognized bacterial phyla were candidate phyla (i.e. have no cultured representatives). There are no fixed rules to the nomenclature of bacterial phyla. It was proposed that the suffix "-bacteria" be used for phyla. List of bacterial phyla The following is a list of bacterial phyla that have been proposed. Supergroups Despite the unclear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
