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PPP2CA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that (in humans) is encoded by the ''PPP2CA'' gene. Function This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. Interactions PPP2CA has been shown to interact with: * Bcl-2, * Bestrophin 1, * CCNG2, * CTTNBP2NL, * CTTNBP2, * Cyclin-dependent kinase 2, * Cyclin-dependent kinase 6, * FAM40A, * IGBP1, * MOBKL3, * PPP2R1A, * PPP2R1B, * PPP2R2A, * PPP2R3B, * PPP2R5A, * PPP2R5B, * PPP2R5C, * PPP2R5D, * PPP2R5E, * STRN3, * STRN, and * TLX1. See also *PPP2CB Serine/threonine-protein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TLX1
T-cell leukemia homeobox protein 1 is a protein that in humans is encoded by the ''TLX1'' gene, which was initially named ''HOX11''. Interactions TLX1 has been shown to interact with PPP1CC, PPP2CB and PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that (in humans) is encoded by the ''PPP2CA'' gene. Function This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the fou .... References Further reading * * * * * * * * * * * * * * * * * {{gene-10-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R1A
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform is an enzyme that in humans is encoded by the ''PPP2R1A'' gene. In the plant Arabidopsis thaliana a similar enzyme is encoded by the RCN1 gene (At1g25490). Function This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Interactions PPP2R1A has been shown to interact with: * CTTNBP2NL, * FAM40A, * PPP2CB, PPP2CA, PPP4C, * PPP2R2A, * P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
STRN
Striatin is a protein that in humans is encoded by the ''STRN'' gene. Interactions STRN has been shown to interact with: * CTTNBP2NL, * CTTNBP2, * FAM40A, * MOBKL3, * PDCD10, * PPP2CA, * PPP2R1A, * RP6-213H19.1, * STK24, * STK25, * STRN3, and * TRAF3IP3 TRAF3-interacting JNK-activating modulator is a protein that in humans is encoded by the ''TRAF3IP3'' gene. Model organisms Model organisms have been used in the study of TRAF3IP3 function. A conditional knockout mouse line, called ''Traf3ip3tm1 .... References Further reading * * * * * * * {{Gene-2-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
STRN3
Striatin-3 is a protein that in humans is encoded by the ''STRN3'' gene. Interactions STRN3 has been shown to interact with: * CTTNBP2NL, * CTTNBP2, * FAM40A, * MOBKL3, * PDCD10, * PPP2CA, * PPP2R1A, * RP6-213H19.1, * STK24, and * STRN Striatin is a protein that in humans is encoded by the ''STRN'' gene. Interactions STRN has been shown to interact with: * CTTNBP2NL, * CTTNBP2, * FAM40A, * MOBKL3, * PDCD10, * PPP2CA, * PPP2R1A, * RP6-213H19.1, * STK24, * STK25, * .... References Further reading * * * * * * * * {{gene-14-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform is an enzyme that in humans is encoded by the ''PPP2R5E'' gene. Function The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Interactions PPP2R5E has been shown to interact with PPP2R1B and PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that (in humans) is encoded by the ''PPP2CA'' gene. Function This gene encodes the phosphatase 2A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the ''PPP2R5D'' gene. Mutations in ''PPP2R5D'' cause Jordan's Syndrome. Function The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. Interactions PPP2R5D has been shown to interact with: * HAND2, * PPP2CA, * PPP2R1B, and * liprin-alpha-1 Liprin-alpha-1 is a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R5C
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform is an enzyme that in humans is encoded by the ''PPP2R5C'' gene. Function The product of this gene belongs to the Protein phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. Interactions PPP2R5C has been shown to interact with PPP2R1B, PPP2CA and PPP2R5A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform is a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform is an enzyme that in humans is encoded by the ''PPP2R5B'' gene. Function The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. Interactions PPP2R5B has been shown to interact with PPP2R1B and PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that (in humans) is encoded by the ''PPP2CA'' gene. Function This gene encodes the phosphatase 2A catalyt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform is an enzyme that in humans is encoded by the ''PPP2R5A'' gene. Function The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Interactions PPP2R5A has been shown to interact with: * AXIN1, * CTLA-4, * PPP2CA, * PPP2R1A, * PPP2R1B, and * PPP2R5C Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform is an enzyme that in humans is encoded by the ''PPP2R5C'' ge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R3B
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta is an enzyme that in humans is encoded by the ''PPP2R3B'' gene. Function Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PPP2R2A
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform is an enzyme regulator that in humans is encoded by the ''PPP2R2A'' gene. Function The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Interactions PPP2R2A has been shown to interact with: * P70-S6 Kinase 1, * PPP2CA, * PPP2R1A, * PPP2R1B, * TGF beta receptor 1, and * p107 The P107 was a World War II French half-track. History In the 1920s and 1930s Citroën developed a long li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MOBKL3
Mps one binder kinase activator-like 3 is an enzyme that in humans is encoded by the ''MOBKL3'' gene. Function This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Interactions MOBKL3 has been shown to interact with: * CTTNBP2NL, * CTTNBP2, * FAM40A, * PDCD10, * PPP2CA, * RP6-213H19.1, * STK24, * STK25, * STRN3, * STRN, and * TRAF3IP3 TRAF3-interacting JNK-activating modulator is a protein that in humans is encoded by the ''TRAF3IP3'' gene. Model organisms Model organisms have been used in the study of TRAF3IP3 function. A conditional knockout mouse line, called ''Traf3ip3tm1 .... References Further reading * * * * {{gene-2-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |