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POLR1C
DNA-directed RNA polymerases I and III subunit RPAC1 is a protein that in humans is encoded by the ''POLR1C'' gene. Interactions POLR1C has been shown to interact with CD3EAP, POLR1E and POLR1D DNA-directed RNA polymerases I and III subunit RPAC2 is a protein that in humans is encoded by the ''POLR1D'' gene. Interactions POLR1D has been shown to Protein-protein_interaction, interact with POLR1C. References Further reading .... References Further reading * * * * * * * * * * * * {{Gene-6-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CD3EAP
DNA-directed RNA polymerase I subunit RPA34 is an enzyme that in humans is encoded by the ''CD3EAP'' gene. Interactions CD3EAP has been shown to interact with T-cell surface glycoprotein CD3 epsilon chain CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the ''CD3E'' gene which resides on chromosome 11. Function The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, ..., POLR1E and POLR1C. References Further reading * * * * * * * * External links * * {{gene-19-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
POLR1E
DNA-directed RNA polymerase I subunit RPA49 is an enzyme that in humans is encoded by the ''POLR1E'' gene. Model organisms Model organisms have been used in the study of POLR1E function. A conditional knockout mouse line, called ''Polr1etm1a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program—a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty seven tests were carried out on mutant mice and two significant abnormalities were observed. No homozygous mutant embryos were identified during gestation, and therefore none survived until weaning. The remaining tests were carried out on heterozygous mutant adult mice; no additional significant abnormalities were observed in these animals. Interactions POLR1E has been shown to interact with CD3EAP and POLR1C DNA-direct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
