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Orungo Virus
Orungo virus (ORUV) is an arbovirus of the genus ''Orbivirus'', the subfamily ''Sedoreovirinae'' and the family ''Reoviridae''. There are four known subtypes of Orungo virus designated Orungo-1 (ORUV-1), Orungo-2 (ORUV-2), Orungo-3 (ORUV-3), and Orungo-4 (ORUV-4). It was first isolated by the Uganda Virus Research Institute in Entebbe, Uganda by Oyewale Tomori Oyewale Tomori (born 3 February 1946, Osun State, Nigeria) is a Nigerian professor of virology, educational administrator, and former vice chancellor of Redeemer's University. Life and career Tomori was born in Ilesa, Osun State, Nigeria on 3 F ... and colleagues. Antibodies to the virus have been found in humans, monkeys, sheep, and cattle. References Orbiviruses {{Virus-stub ...
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Arbovirus
Arbovirus is an informal name for any virus that is transmitted by arthropod vectors. The term ''arbovirus'' is a portmanteau word (''ar''thropod-''bo''rne ''virus''). ''Tibovirus'' (''ti''ck-''bo''rne ''virus'') is sometimes used to more specifically describe viruses transmitted by ticks, a superorder within the arthropods. Arboviruses can affect both animals (including humans) and plants. In humans, symptoms of arbovirus infection generally occur 3–15 days after exposure to the virus and last three or four days. The most common clinical features of infection are fever, headache, and malaise, but encephalitis and viral hemorrhagic fever may also occur. Signs and symptoms The incubation period – the time between when infection occurs and when symptoms appear – varies from virus to virus, but is usually limited between 2 and 15 days for arboviruses. The majority of infections, however, are asymptomatic. Among cases in which symptoms do appear, symptoms tend to be non-s ...
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Orbivirus
''Orbivirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae'' and subfamily ''Sedoreovirinae''. Unlike other reoviruses, orbiviruses are arboviruses. They can infect and replicate within a wide range of arthropod and vertebrate hosts. Orbiviruses are named after their characteristic doughnut-shaped capsomers (''orbis'' in Latin means ring). Many orbiviruses are transmitted by ticks or haematophagus insect vectors (''Culicoides'', mosquitoes and sand flies) and have a wide host range that includes cattle, goats and sheep, wild ruminants, equids, camelids, marsupials, sloths, bats, birds, large canine and feline carnivores, and humans. The three economically most important orbiviruses are ''Bluetongue virus'', ''African horse sickness virus'', and ''Epizootic hemorrhagic disease virus'', all of which are transmitted by ''Culicoides'' species. The genus contains 22 species and at least 130 different serotypes. History In 1719, African horse sickness viru ...
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Sedoreovirinae
''Sedoreovirinae'' (''sedo'' = smooth) is a subfamily of the ''Reoviridae'' family of viruses. Viruses in this subfamily are distinguished by the absence of a turreted protein on the inner capsid to produce a smooth surface. Characteristics Like other members of the ''Reoviridae'' family, viruses of the ''Sedoreovirinae'' subfamily are made of naked, icosahedral capsids containing 10-12 segments of linear double-stranded RNA (dsRNA). The Baltimore System of viral classification categorizes ''Reoviridae'' in Group III. Importance Viruses classified in the ''Sedoreovirinae'' subfamily infect a wide range of plants and animals, including some that can infect humans. There is not only the potential of a few of these viruses to cause human disease, but also to reduce the supply of crops and livestock. Viruses Genus ''Cardoreovirus'' '' Eriocheir sinensis reovirus'' was isolated out of a Chinese mitten crab ('' Eriocheir sinensis''). No currently known associated disease. Genus ''Mi ...
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Reoviridae
''Reoviridae'' is a family of double-stranded RNA viruses. Member viruses have a wide host range, including vertebrates, invertebrates, plants, protists and fungi. They lack lipid envelopes and package their segmented genome within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional structures of these large complex viruses (diameter ∼60–100 nm) to be obtained, revealing a structural and likely evolutionary relationship to the cystovirus family of bacteriophage. There are currently 97 species in this family, divided among 15 genera in two subfamilies. Reoviruses can affect the gastrointestinal system (such as rotaviruses) and respiratory tract. The name "reo-" is an acronym for "''r''espiratory ''e''nteric ''o''rphan" viruses''.'' The term "orphan virus" refers to the fact that some of these viruses have been observed not associated with any known disease. Even though viruses in the family ''Reoviridae'' have more recently been identified with vario ...
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Uganda Virus Research Institute
The Uganda Virus Research Institute (UVRI) is a medical research institute owned by the Uganda government that carries out research on communicable diseases in man and animals, with emphasis on viral transmitted infections. UVRI is a component of Uganda National Health Research Organization (UNHRO), an umbrella organization for health research within Uganda. Location UVRI is located at 51-59 Nakiwogo Road, in Entebbe, Uganda, approximately , south of Kampala, the capital and largest city in Uganda. The coordinates of the institute are: 0°04'33.0"N, 32°27'26.0"E (Latitude:0.075833; Longitude:32.457222). Overview The organisation was established in 1936 as the Yellow Fever Research Institute by the Rockefeller Foundation. In 1947, scientists researching yellow fever placed a rhesus macaque in a cage in the Zika Forest. The monkey developed a fever, and researchers isolated from its serum a transmissible agent that was first described as Zika virus in 1952. Other noteworthy arb ...
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Entebbe
Entebbe is a city in Central Uganda. Located on a Lake Victoria peninsula, approximately southwest of the Ugandan capital city, Kampala. Entebbe was once the seat of government for the Protectorate of Uganda prior to independence, in 1962. The city is the location of Entebbe International Airport, Uganda's largest commercial and military airport, best known for the Israeli rescue of 100 hostages kidnapped by the militant group of the PFLP-EO and Revolutionary Cells (RZ) organizations. Entebbe is also the location of State House, the official office and residence of the President of Uganda. Etymology The word came from Luganda language ''e ntebe'' which means 'seat' / 'chair'. Entebbe was a cultural site for the Mamba clan and it was called "entebbe za Mugula" - Mugula was the title of a chief of a subdivision of the Mamba clan - and is now the location of the official office and residence of the President of Uganda, as it was for British governors before independence. Entebbe ...
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Uganda
}), is a landlocked country in East Africa East Africa, Eastern Africa, or East of Africa, is the eastern subregion of the African continent. In the United Nations Statistics Division scheme of geographic regions, 10-11-(16*) territories make up Eastern Africa: Due to the historical .... The country is bordered to the east by Kenya, to the north by South Sudan, to the west by the Democratic Republic of the Congo, to the south-west by Rwanda, and to the south by Tanzania. The southern part of the country includes a substantial portion of Lake Victoria, shared with Kenya and Tanzania. Uganda is in the African Great Lakes region. Uganda also lies within the Nile, Nile basin and has a varied but generally a modified equatorial climate. It has a population of around 49 million, of which 8.5 million live in the Capital city, capital and largest city of Kampala. Uganda is named after the Buganda kingdom, which encompasses a large portion of the south of the country, includi ...
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Oyewale Tomori
Oyewale Tomori (born 3 February 1946, Osun State, Nigeria) is a Nigerian professor of virology, educational administrator, and former vice chancellor of Redeemer's University. Life and career Tomori was born in Ilesa, Osun State, Nigeria on 3 February 1946. He received a Doctor of Veterinary Medicine(DVM) from Ahmadu Bello University, Zaria as well as a Doctorate degree, Ph.D in virology from the University of Ibadan, Oyo State, Nigeria where he was appointed professor of virology in 1981, the same year he received the United States Department of Health and Human Services Public Health Service Certificate for contributions to Lassa Fever Research. Three years (1984) after his appointment as a professor of virology, he was appointed the head of the Department of Virology. At the University of Ibadan Tomori's research interest focuses on viral infections including Ebola hemorrhagic fever, yellow fever, Lassa fever. He served as the Regional Virologist for the World Health Organiza ...
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