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Ohio State University College Of Medicine
The Ohio State University College of Medicine (formerly known as The Ohio State University College of Medicine and Public Health) is the medical school at The Ohio State University and is located in Columbus, Ohio. The college is nationally recognized as a top institution in both education and research, as reflected by rankings in '' U.S. News & World Report''. In 2009, its two primary teaching hospital (The Ohio State University Wexner Medical Center and Nationwide Children's Hospital) were ranked as one of the best hospitals in the U.S. in 10 different specialties; and named to ''U.S. News & World Report's'' select honor roll of U.S. hospitals. History The OSU College of Medicine can trace its roots as far back as March 3, 1834, with the founding of the Willoughby University of Lake Erie in Willoughby, Ohio. Dr. Westel Willoughby (1789–1844), the school's namesake and first president, oversaw the operation of the school until 1843, when a disagreement among the faculty l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ohio State University
The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, it has been ranked by major institutional rankings among the best public universities in the United States. Founded in 1870 as the state's land-grant university and the ninth university in Ohio with the Morrill Act of 1862, Ohio State was originally known as the Ohio Agricultural and Mechanical College and focused on various agricultural and mechanical disciplines, but it developed into a comprehensive university under the direction of then-Governor and later U.S. president Rutherford B. Hayes, and in 1878, the Ohio General Assembly passed a law changing the name to "the Ohio State University" and broadening the scope of the university. Admission standards tightened and became greatly more selective throughout the 2000s and 2010s. Ohio State's political science department and faculty have greatly contri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ohio State East Hospital
The Ohio State University Wexner Medical Center East Hospital is a university hospital in King-Lincoln Bronzeville, Columbus, Ohio. The hospital has a Level III trauma center, an emergency department, and provides numerous inpatient and outpatient services. It is part of the Wexner Medical Center, administered by the Ohio State University. The Ohio State University maintains its orthopedic, wound care, and specialty blood vessel surgery programs at the hospital. As of 2013, it is the neighborhood's largest employer, and only expected to expand its presence there. History The facility first opened in 1890, then known as St. Anthony's Hospital. The hospital's west wings were built in the 1960s. It gained its most distinctive feature in 1971 a tall cylindrical tower. The 16-story tower was designed with all private rooms, unique in 1971. In 1992, Quorum Health Group purchased it, renaming it Park Medical Center. The Ohio State University (OSU) acquired it for about $13 million in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. Occasionally, spread may occur to the brain, skin, or gums. As an acute leukemia, AML progresses rapidly, and is typically fatal within weeks or months if left untreated. Risk factors include smoking, previous chemotherapy or radiation therapy, myelodysplastic syndrome, and exposure to the chemical benzene. The underlying mechanism involves replacement of normal bone marrow with leukemia cells, which results in a drop in red blood cells, platelets, and normal white blood cells. Diagnosis is generally based on bone marrow aspiration and specific blood tests. AML has several subtypes for which treatments and outcomes may vary. The fir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hunt And Hess Scale
The Hunt and Hess scale, introduced in 1968, is one of the grading systems used to classify the severity of a subarachnoid hemorrhage based on the patient's clinical condition. It is used as a predictor of patient's prognosis/outcome, with a higher grade correlating to lower survival rate. Other scales which describe the clinical presentation of subarachnoid hemorrhage patients include the World Federation of Neurosurgical Societies classification, which combines consciousness and motor deficit in its scoring. The scale is named for Dr. William E. Hunt (26 November 1921 - 26 January 1999) and Dr. Robert McDonald Hess (24 June 1931 - 3 October 2019) Description grade # Asymptomatic, mild headache, slight nuchal rigidity #Moderate to severe headache, nuchal rigidity, no neurologic deficit other than cranial nerve palsy #Drowsiness, confusion, mild focal neurologic deficit # Stupor, moderate-severe hemiparesis Hemiparesis, or unilateral paresis, is weakness of one entire side o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert De La Chappelle
Albert may refer to: Companies * Albert (supermarket), a supermarket chain in the Czech Republic * Albert Heijn, a supermarket chain in the Netherlands * Albert Market, a street market in The Gambia * Albert Productions, a record label * Albert Computers, Inc., a computer manufacturer in the 1980s Entertainment * ''Albert'' (1985 film), a Czechoslovak film directed by František Vláčil * ''Albert'' (2015 film), a film by Karsten Kiilerich * ''Albert'' (2016 film), an American TV movie * ''Albert'' (Ed Hall album), 1988 * "Albert" (short story), by Leo Tolstoy * Albert (comics), a character in Marvel Comics * Albert (''Discworld''), a character in Terry Pratchett's ''Discworld'' series * Albert, a character in Dario Argento's 1977 film ''Suspiria'' Military * Battle of Albert (1914), a WWI battle at Albert, Somme, France * Battle of Albert (1916), a WWI battle at Albert, Somme, France * Battle of Albert (1918), a WWI battle at Albert, Somme, France People * Albert (given n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inferior Vena Cava Filter
An inferior vena cava filter is a medical device made of metal that is implanted by vascular surgeons or interventional radiologists into the inferior vena cava to prevent a life-threatening pulmonary embolism (PE) or venous thromboembolism (VTE). The filter is designed to trap a blood clot and prevent its travel to the lung where it would form a pulmonary embolism. Their effectiveness and safety profile is well established, and they may be used when anticoagulant treatment is not sufficient. Results from the PREPIC study and other studies which have shown many long-term complications of IVC filters led to the introduction of retrievable IVC filters. The first retrievable IVC filters were approved by FDA in 2003 and 2004. In 2012, the American College of Chest Physicians recommended IVC filters for those with contraindications to anticoagulation who either have acute PE or acute proximal (above the knee) deep vein thrombosis (DVT). History The first IVC filter was created by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kazi Mobin-Uddin
Kazi Mobin-Uddin (July 16, 1930 – June 10, 1999) was an American surgeon specializing in vascular surgery research. Early life He was born in British India and educated at the Aligarh Muslim University. Career In 1969 he developed the first Inferior vena cava filter while on faculty at University of Miami for patients with deep vein thrombosis. He published his findings in New England Journal of Medicine and Archives of Surgery. Till then patients with deep vein thrombosis required a high-risk invasive surgical procedure to prevent thrombus embolization to the pulmonary artery. Newsweek magazine reported on the discovery in its October 20, 1969 issue calling it "Umbrella of life." The Mobin-Uddin umbrella was released for general clinical use in 1970. American College of Chest Physicians has incorporated Inferior vena cava filter into guidelines for management of deep vein thrombosis in their 2012 guidelines. Over 50,000 Inferior vena cava filter are placed in Unit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deoxycoformycin
Pentostatin (or deoxycoformycin, trade name Nipent, manufactured by SuperGen) is an anticancer chemotherapeutic drug. Mechanism It is classified as a purine analog, which is a type of antimetabolite. It mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, interfering with the cell's ability to process DNA. Cancer cells generally divide more often than healthy cells; DNA is highly involved in cell division ( mitosis) and drugs which target DNA-related processes are therefore more toxic to cancer cells than healthy cells. Uses Pentostatin is used to treat hairy cell leukemia Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. It is usually classified as a subtype of chronic lymphocytic leukemia (CLL). Hairy cell leukemia makes up about 2% of all leu .... It is given by intravenous infusion once every two weeks for three to six months. Additionally, pentostatin has been used to t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hairy Cell Leukemia
Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. It is usually classified as a subtype of chronic lymphocytic leukemia (CLL). Hairy cell leukemia makes up about 2% of all leukemias, with fewer than 2,000 new cases diagnosed annually in North America and Western Europe combined. Hairy cell leukemia (HCL) was originally described as histiocytic leukemia, malignant reticulosis, or lymphoid myelofibrosis in publications dating back to the 1920s. The disease was formally named leukemic reticuloendotheliosis, and its characterization was significantly advanced by Bertha Bouroncle and colleagues at the Ohio State University College of Medicine in 1958. Its common name, which was coined in 1966, is derived from the "hairy" appearance of the malignant B cells under a microscope. Signs and symptoms In HCL, the "hairy cells" (malignant B lymphocytes) accumulate in the bone marrow, interfering with the production of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bertha Bouroncle
Bertha A. Bouroncle Pereny (September 10, 1919 – August 13, 2013) was a Peruvian-American hematologist. After completing medical school in Peru, Bouroncle came to the United States for her postgraduate medical training. A longtime member of the faculty at the Ohio State University College of Medicine, she was the first investigator to identify hairy cell leukemia and the first female full professor in the state of Ohio. In the 1980s, Bouroncle and two colleagues developed a drug to treat hairy cell leukemia. She was named a professor emerita at the medical school in 1989. Bouroncle died in 2013. She was predeceased by her husband Andrew Pereny, a businessman and erstwhile ceramic artist. Early life Bouroncle was born in Trujillo, Peru. She was the fourth of five children in her family. Bouroncle, whose father Luis was a Harvard University alumnus, went to medical school at the National University of San Marcos. When she was not studying, Bouroncle gained experience by providing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dobutamine
Dobutamine is a medication used in the treatment of cardiogenic shock (as a result of inadequate tissue perfusion) and severe heart failure. It may also be used in certain types of cardiac stress tests. It is given by IV only, as an injection into a vein or intraosseous as a continuous infusion. The amount of medication needs to be adjusted to the desired effect. Onset of effects is generally seen within 2 minutes. It has a half-life of two minutes. This drug is generally only administered short term, although it may be used for longer periods to relieve symptoms of heart failure in patients awaiting heart transplantation. Common side effects include a fast heart rate, an irregular heart beat, and inflammation at the site of injection. Use is not recommended in those with idiopathic hypertrophic subaortic stenosis. It primarily works by direct stimulation of β1 receptors, which increases the strength of the heart's contractions, leading to a positive ionotrophic effect. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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