Bertha A. Bouroncle Pereny (September 10, 1919 – August 13, 2013) was a Peruvian-American
hematologist
Hematology (American and British English spelling differences#ae and oe, always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to ...
. After completing medical school in Peru, Bouroncle came to the United States for her postgraduate medical training. A longtime member of the faculty at the
Ohio State University College of Medicine
The Ohio State University College of Medicine (formerly known as The Ohio State University College of Medicine and Public Health) is the medical school at The Ohio State University and is located in Columbus, Ohio. The college is nationally re ...
, she was the first investigator to identify
hairy cell leukemia
Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. It is usually classified as a subtype of chronic lymphocytic leukemia (CLL). Hairy cell leukemia makes up about 2% of all le ...
and the first female full professor in the state of Ohio.
In the 1980s, Bouroncle and two colleagues developed a drug to treat hairy cell leukemia. She was named a professor emerita at the medical school in 1989. Bouroncle died in 2013. She was predeceased by her husband Andrew Pereny, a businessman and erstwhile ceramic artist.
Early life
Bouroncle was born in
Trujillo, Peru
Trujillo (; qu, Truhillu) is a city in coastal northwestern Peru and the capital of the Department of La Libertad. It is the third most populous city and center of the List of metropolitan areas of Peru, third most populous metropolitan area of P ...
. She was the fourth of five children in her family. Bouroncle, whose father Luis was a
Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
alumnus, went to medical school at the
National University of San Marcos
The National University of San Marcos ( es, Universidad Nacional Mayor de San Marcos, link=no, UNMSM) is a public research university located in Lima, the capital of Peru. It is considered the most important, recognized and representative educ ...
. When she was not studying, Bouroncle gained experience by providing free medical care to fishermen in
Pucusana
Pucusana is a town in Central Peru, capital of the district Pucusana in the province Lima
Lima ( ; ), originally founded as Ciudad de Los Reyes (City of The Kings) is the capital and the largest city of Peru. It is located in the valleys of ...
.
[ She also held a job as a laboratory research assistant, leading to an interest in hematology.][ The only female in her medical school graduating class in 1947, Bouroncle was the class valedictorian.][
]
Career
In 1948, Bouroncle left Peru to complete a postdoctoral fellowship at Ohio State. Between 1949 and 1953, she completed residency and fellowship training at the university in internal medicine and hematology. She spent the next year at Ohio State as a chief resident in medicine; she was the first female in Ohio to serve as a chief resident. Bouroncle was hired at Ohio State in the hematology-oncology division as an assistant professor in 1954. Bouroncle was named an associate professor in 1957.
Working with two junior colleagues the next year, Bouroncle identified a blood disorder known as hairy cell leukemia. She was named a full professor in 1970 and a professor emerita in 1989. She was the first female full professor of a medical school in Ohio. For many years, Bouroncle was on the medical staff of the Ohio State University Hospital. Among her colleagues, Bouroncle was noted for her commanding presence in spite of her small stature. Her associates said that she held trainees to very high standards without making them feel badly about themselves. She considered herself to be a shy person, but she found that she could open her heart to her patients.
Continuing her research with hairy cell leukemia, Bouroncle worked with Ohio State investigators Michael Grever and Eric Kraut in the 1980s to develop a treatment for the disease known as deoxycoformycin
Pentostatin (or deoxycoformycin, trade name Nipent, manufactured by SuperGen) is an anticancer chemotherapeutic drug.
Mechanism
It is classified as a purine analog, which is a type of antimetabolite.
It mimics the nucleoside adenosine and thus ...
. She helped to found The James Cancer Hospital
The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (commonly shortened to just The James) is part of The Ohio State University and one of the 45 National Comprehensive Cancer hospitals. It is named after Arthur G. Jame ...
, which opened at Ohio State in 1990. She won several teaching-related awards at Ohio State.[
]
Personal life
In 1960, Bouroncle met businessman Andrew Pereny in Peru and they later married. Before he had become successful in business, Pereny produced a collection of ceramic art between 1933 and 1938. Several decades later, Pereny's work piqued the interest of art collectors because of his brief tenure as an artist. Pereny died in 1983.
Bouroncle funded the Bertha Bouroncle, MD, and Andrew Pereny Chair of Medicine at Ohio State. Outside of medicine, Bouroncle enjoyed the Columbus Symphony Orchestra
The Columbus Symphony Orchestra (CSO) is an American symphony orchestra based in Columbus, Ohio. The oldest performing arts organization in the city, its home is the Ohio Theatre. The orchestra's current Executive Director is Denise Rehg. Ross ...
.
Later life
Ohio State established the Bertha Bouroncle Distinguished Lecture Award in 2001.[ Bouroncle donated $200,000 to the National University of San Marcos to build a new research laboratory. The school named the laboratory in her honor.] She died at the Richard M. Ross Heart Hospital in 2013.[
]
References
{{DEFAULTSORT:Bouroncle, Bertha A.
1919 births
2013 deaths
American hematologists
Peruvian women physicians
People from Trujillo, Peru
National University of San Marcos alumni
Ohio State University faculty
Women hematologists
20th-century American women physicians
20th-century American physicians
American women academics
Peruvian emigrants to the United States
21st-century American women