Ocean Biomedical
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Ocean Biomedical
Ocean Biomedical is a new-generation American biopharmaceutical company based in Providence, Rhode Island. The company has product candidates addressing malaria, pulmonary fibrosis, and lung cancer. Ocean Biomedical was founded by Indian-American physician Chirinjeev Kathuria with Scientific Co-founders Jack Elias and Dr. Jonathan Kurtis, both from Brown University’s Medical School faculty. They aim to build a pipeline of preclinical, clinical, and commercial drug development by bringing together interdisciplinary expertise and resources. History In January 2019 Chirinjeev Kathuria co-founded Ocean Biomedical in Rhode Island, United States. The company was also co-founded by Jack Elias, who was Dean of Medicine at Brown University at the time, but currently works as a senior health advisor at Brown. Ocean Biomedical started off as a Brown University biotech "spin-off." The biopharmaceutical company is currently based in Province, Rhode Island. As of 2021 the CEO of the company ...
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Chirinjeev Kathuria
Chirinjeev Kathuria is an Indian-American investor, physician, politician, businessperson, and philanthropist. He was the first Indian-American to run for the US Senate. Kathuria is the co-founder and co-chairman of UpHealth Inc. which went public on the NYSE (NYSE:UPH) and the executive chairman and co-founder of Ocean Biomedical Inc., a biotech company that partners with leading scientists and research institutions to accelerate the translation of new discoveries into breakthrough medicines. He is also the co-founder and chairman of New Generation Power International, and co-founder of PlanetSpace. Additionally, Kathuria is the co-founder and chairman of the AIRO Group. The AIRO Group brings together technologies and services in urban air mobility, commercial and military aviation, and avionics. Kathuria ran unsuccessfully in the 2004 United States Senate election in Illinois, in which future President Barack Obama was the winner. Early life Chirinjeev Kathuria was born in N ...
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Providence, Rhode Island
Providence is the capital and most populous city of the U.S. state of Rhode Island. One of the oldest cities in New England, it was founded in 1636 by Roger Williams, a Reformed Baptist theologian and religious exile from the Massachusetts Bay Colony. He named the area in honor of "God's merciful Providence" which he believed was responsible for revealing such a haven for him and his followers. The city developed as a busy port as it is situated at the mouth of the Providence River in Providence County, at the head of Narragansett Bay. Providence was one of the first cities in the country to industrialize and became noted for its textile manufacturing and subsequent machine tool, jewelry, and silverware industries. Today, the city of Providence is home to eight hospitals and List of colleges and universities in Rhode Island#Institutions, eight institutions of higher learning which have shifted the city's economy into service industries, though it still retains some manufacturin ...
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Malaria Vaccine
A malaria vaccine is a vaccine that is used to prevent malaria. The only approved use of a vaccine outside the EU, as of 2022, is RTS,S, known by the brand name ''Mosquirix''. In October 2021, the WHO for the first time recommended the large-scale use of a malaria vaccine for children living in areas with moderate-to-high malaria transmission. Four injections are required for full protection. Research continues with other malaria vaccines. The most effective malaria vaccine is R21/Matrix-M, with a 77% efficacy rate shown in initial trials and significantly higher antibody levels than with the RTS,S vaccine. It is the first vaccine that meets the World Health Organization's (WHO) goal of a malaria vaccine with at least 75% efficacy. Approved vaccines RTS,S RTS,S, developed by PATH Malaria Vaccine Initiative (MVI) and GlaxoSmithKline (GSK) with support from the Bill and Melinda Gates Foundation, is the most recently developed recombinant vaccine. It consists of the ''P. falci ...
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Alpert Medical School
The Warren Alpert Medical School (formerly known as Brown Medical School, previously known as Brown University School of Medicine) is the medical school of Brown University, located in Providence, Rhode Island. Originally established in 1811, it was the third medical school to be founded in New England after only Harvard and Dartmouth. However, the original program was suspended in 1827, and the four-year medical program was re-established almost 150 years later in 1972, granting the first MD degrees in 1975. Today, the Warren Alpert Medical School is a component of Brown’s Division of Biology and Medicine, which also includes the Program in Biology. Together with the Medical School’s seven affiliated teaching hospitals, the Division attracts over $300 million in external research funding per year. Alpert Medical School earned ranked 14th for primary care education and 35th for research in the 2023 ''U.S. News & World Report'' rankings, and was ranked among the top 25 medic ...
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Rhode Island
Rhode Island (, like ''road'') is a U.S. state, state in the New England region of the Northeastern United States. It is the List of U.S. states by area, smallest U.S. state by area and the List of states and territories of the United States by population, seventh-least populous, with slightly fewer than 1.1 million residents 2020 United States census, as of 2020, but it is the List of U.S. states by population density, second-most densely populated after New Jersey. It takes its name from Aquidneck Island, the eponymous island, though most of its land area is on the mainland. Rhode Island borders Connecticut to the west; Massachusetts to the north and east; and the Atlantic Ocean to the south via Rhode Island Sound and Block Island Sound. It also shares a small maritime border with New York (state), New York. Providence, Rhode Island, Providence is its capital and most populous city. Native Americans lived around Narragansett Bay for thousands of years before English settler ...
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Brown University
Brown University is a private research university in Providence, Rhode Island. Brown is the seventh-oldest institution of higher education in the United States, founded in 1764 as the College in the English Colony of Rhode Island and Providence Plantations. Brown is one of nine colonial colleges chartered before the American Revolution. Admissions at Brown is among the most selective in the United States. In 2022, the university reported a first year acceptance rate of 5%. It is a member of the Ivy League. Brown was the first college in the United States to codify in its charter that admission and instruction of students was to be equal regardless of their religious affiliation. The university is home to the oldest applied mathematics program in the United States, the oldest engineering program in the Ivy League, and the third-oldest medical program in New England. The university was one of the early doctoral-granting U.S. institutions in the late 19th century, adding masters ...
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Non-small Cell Lung Cancer
Non-small-cell lung cancer (NSCLC) is any type of epithelial lung cancer other than small-cell lung carcinoma (SCLC). NSCLC accounts for about 85% of all lung cancers. As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small-cell carcinoma. When possible, they are primarily treated by surgical resection with curative intent, although chemotherapy has been used increasingly both preoperatively ( neoadjuvant chemotherapy) and postoperatively (adjuvant chemotherapy). Types The most common types of NSCLC are squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma, but several other types occur less frequently. A few of the less common types are pleomorphic, carcinoid tumor, salivary gland carcinoma, and unclassified carcinoma. All types can occur in unusual histologic variants and as mixed cell-type combinations. Nonsquamous-cell carcinoma almost occupies the half of NSCLC. In the tissue classification, the central type contains about one-ninth. So ...
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Pulmonary Fibrosis
Pulmonary fibrosis is a condition in which the lungs become scarred over time. Symptoms include shortness of breath, a dry cough, feeling tired, weight loss, and nail clubbing. Complications may include pulmonary hypertension, respiratory failure, pneumothorax, and lung cancer. Causes include environmental pollution, certain medications, connective tissue diseases, infections, and interstitial lung diseases. Idiopathic pulmonary fibrosis (IPF), an interstitial lung disease of unknown cause, is most common. Diagnosis may be based on symptoms, medical imaging, lung biopsy, and lung function tests. There is no cure and there are limited treatment options available. Treatment is directed towards efforts to improve symptoms and may include oxygen therapy and pulmonary rehabilitation. Certain medications may be used to try to slow the worsening of scarring. Lung transplantation may occasionally be an option. At least 5 million people are affected globally. Life expectancy is gener ...
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Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ...
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Malaria Vaccine
A malaria vaccine is a vaccine that is used to prevent malaria. The only approved use of a vaccine outside the EU, as of 2022, is RTS,S, known by the brand name ''Mosquirix''. In October 2021, the WHO for the first time recommended the large-scale use of a malaria vaccine for children living in areas with moderate-to-high malaria transmission. Four injections are required for full protection. Research continues with other malaria vaccines. The most effective malaria vaccine is R21/Matrix-M, with a 77% efficacy rate shown in initial trials and significantly higher antibody levels than with the RTS,S vaccine. It is the first vaccine that meets the World Health Organization's (WHO) goal of a malaria vaccine with at least 75% efficacy. Approved vaccines RTS,S RTS,S, developed by PATH Malaria Vaccine Initiative (MVI) and GlaxoSmithKline (GSK) with support from the Bill and Melinda Gates Foundation, is the most recently developed recombinant vaccine. It consists of the ''P. falci ...
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Companies Based In Providence, Rhode Island
A company, abbreviated as co., is a legal entity representing an association of people, whether natural, legal or a mixture of both, with a specific objective. Company members share a common purpose and unite to achieve specific, declared goals. Companies take various forms, such as: * voluntary associations, which may include nonprofit organizations * business entities, whose aim is generating profit * financial entities and banks * programs or educational institutions A company can be created as a legal person so that the company itself has limited liability as members perform or fail to discharge their duty according to the publicly declared incorporation, or published policy. When a company closes, it may need to be liquidated to avoid further legal obligations. Companies may associate and collectively register themselves as new companies; the resulting entities are often known as corporate groups. Meanings and definitions A company can be defined as an "artificial per ...
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