Nurse Cell
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Nurse Cell
In general biology or reproductive physiology the term nurse cell is defined as a cell which provides food, helps other cells and provides stability to their neighboring cells. The term nurse cell is used in several unrelated ways in different scientific fields. Human physiology Nurse cells are specialized macrophages residing in the bone marrow that assist in the development of red blood cells. They absorb the nuclei of immature red blood cells and may provide growth factors to help the red blood cells mature. In the bone marrow, immature red blood cells (erythroblasts) can be seen grouped in a cluster around a nurse cell. The epithelial cell found in the cortex of the thymus is also called a "nurse cell." These cells produce Thymic hormones that cause T lymphocytes to mature and differentiate. Parasitology In parasitology, a nurse cell is an infected cell in the disease trichinosis discovered by Dickson Despommier. A trichinella larva enters a cell and develops there, probably a ...
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Macrophage
Macrophages (abbreviated as M φ, MΦ or MP) ( el, large eaters, from Greek ''μακρός'' (') = large, ''φαγεῖν'' (') = to eat) are a type of white blood cell of the immune system that engulfs and digests pathogens, such as cancer cells, microbes, cellular debris, and foreign substances, which do not have proteins that are specific to healthy body cells on their surface. The process is called phagocytosis, which acts to defend the host against infection and injury. These large phagocytes are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. They take various forms (with various names) throughout the body (e.g., histiocytes, Kupffer cells, alveolar macrophages, microglia, and others), but all are part of the mononuclear phagocyte system. Besides phagocytosis, they play a critical role in nonspecific defense (innate immunity) and also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune ...
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Basidiospore
A basidiospore is a reproductive spore produced by Basidiomycete fungi, a grouping that includes mushrooms, shelf fungi, rusts, and smuts. Basidiospores typically each contain one haploid nucleus that is the product of meiosis, and they are produced by specialized fungal cells called basidia. Typically, four basidiospores develop on appendages from each basidium, of which two are of one strain and the other two of its opposite strain. In gills under a cap of one common species, there exist millions of basidia. Some gilled mushrooms in the order Agaricales have the ability to release billions of spores. The puffball fungus ''Calvatia gigantea'' has been calculated to produce about five trillion basidiospores. Most basidiospores are forcibly discharged, and are thus considered ballistospores. These spores serve as the main air dispersal units for the fungi. The spores are released during periods of high humidity and generally have a night-time or pre-dawn peak concentration in the ...
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Thymic Nurse Cell
Thymic nurse cells (TNCs) are large epithelial cells found in the cortex of the thymus and also in cortico-medullary junction.Ritter, M. A., C. A. Sauvage, and S. F. Cotmore. "The human thymus microenvironment: in vivo identification of thymic nurse cells and other antigenically-distinct subpopulations of epithelial cells." Immunology 44.3 (1981): 439. They have their own nucleus and are known to internalize thymocytes through extensions of plasma membrane.Hendrix, Tonya M. et al. “Thymic Nurse Cells Exhibit Epithelial Progenitor Phenotype and Create Unique Extra-Cytoplasmic Membrane Space for Thymocyte Selection.” Cellular immunology 261.2 (2010): 81–92. PMC. Web. 6 Feb. 2017 The cell surfaces of TNCs and their cytoplasmic vacuoles express MHC Class I and MHC Class II antigens. The interaction of these antigens with the developing thymocytes determines whether the thymocytes undergo positive or negative selection. Structure and function Thymic nurse cells (TNCs) are a sub-pop ...
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Sertoli Cell
Sertoli cells are a type of sustentacular "nurse" cell found in human testes which contribute to the process of spermatogenesis (the production of sperm) as a structural component of the seminiferous tubules. They are activated by follicle-stimulating hormone (FSH) secreted by the adenohypophysis and express FSH receptor on their membranes. History Sertoli cells are named after Enrico Sertoli, an Italian physiologist who discovered them while studying medicine at the University of Pavia, Italy. He published a description of his eponymous cell in 1865. The cell was discovered by Sertoli with a Belthle microscope which had been purchased in 1862. In the 1865 publication, his first description used the terms "tree-like cell" or "stringy cell"; most importantly, he referred to these as "mother cells". Other scientists later used Enrico's family name to label these cells in publications, beginning in 1888. As of 2006, two textbooks that are devoted specifically to the Sertoli cell have ...
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Angiogenesis
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis. Angiogenesis continues the growth of the vasculature by processes of sprouting and splitting. Vasculogenesis is the embryonic formation of endothelial cells from mesoderm cell precursors, and from neovascularization, although discussions are not always precise (especially in older texts). The first vessels in the developing embryo form through vasculogenesis, after which angiogenesis is responsible for most, if not all, blood vessel growth during development and in disease. Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in the formation of granulation tissue. However, it is also a fundamental step in the transition of tumors from a benign state to a malignant one, leading to the use of angiogenesis inhibitors in the treatment of cancer. The essential role of angiogenesis in ...
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Cytoplasm
In cell biology, the cytoplasm is all of the material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus. The material inside the nucleus and contained within the nuclear membrane is termed the nucleoplasm. The main components of the cytoplasm are cytosol (a gel-like substance), the organelles (the cell's internal sub-structures), and various cytoplasmic inclusions. The cytoplasm is about 80% water and is usually colorless. The submicroscopic ground cell substance or cytoplasmic matrix which remains after exclusion of the cell organelles and particles is groundplasm. It is the hyaloplasm of light microscopy, a highly complex, polyphasic system in which all resolvable cytoplasmic elements are suspended, including the larger organelles such as the ribosomes, mitochondria, the plant plastids, lipid droplets, and vacuoles. Most cellular activities take place within the cytoplasm, such as many metabolic pathways including glycolysis, and proces ...
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Drosophila
''Drosophila'' () is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''D. melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literature. The entire genus, however, contains more than 1,500 species and is very diverse in appearance, be ...
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Cell Nucleus
The cell nucleus (pl. nuclei; from Latin or , meaning ''kernel'' or ''seed'') is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm; and the nuclear matrix, a network within the nucleus that adds mechanical support. The cell nucleus contains nearly all of the cell's genome. Nuclear DNA is often organized into multiple chromosomes – long stands of DNA dotted with various proteins, such as histones, that protect and organize the DNA. The genes within these chromosomes are structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the cell by regulating gene expres ...
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Oocyte
An oocyte (, ), oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis, forming oogonia. During oogenesis, the oogonia become primary oocytes. An oocyte is a form of genetic material that can be collected for cryoconservation. Formation The formation of an oocyte is called oocytogenesis, which is a part of oogenesis. Oogenesis results in the formation of both primary oocytes during fetal period, and of secondary oocytes after it as part of ovulation. Characteristics Cytoplasm Oocytes are rich in cytoplasm, which contains yolk granules to nourish the cell early in development. Nucleus During the primary oocyte stage of oogenesis, the nucleus is called a germinal vesicle. The only normal human type of secondary oocyte has t ...
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Invertebrate
Invertebrates are a paraphyletic group of animals that neither possess nor develop a vertebral column (commonly known as a ''backbone'' or ''spine''), derived from the notochord. This is a grouping including all animals apart from the chordate subphylum Vertebrata. Familiar examples of invertebrates include arthropods, mollusks, annelids, echinoderms and cnidarians. The majority of animal species are invertebrates; one estimate puts the figure at 97%. Many invertebrate taxa have a greater number and variety of species than the entire subphylum of Vertebrata. Invertebrates vary widely in size, from 50  μm (0.002 in) rotifers to the 9–10 m (30–33 ft) colossal squid. Some so-called invertebrates, such as the Tunicata and Cephalochordata, are more closely related to vertebrates than to other invertebrates. This makes the invertebrates paraphyletic, so the term has little meaning in taxonomy. Etymology The word "invertebrate" comes from the Latin word ''vertebra'', whi ...
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Ribonucleoprotein Particles In The Drosophila Egg Chamber
Nucleoproteins are proteins conjugated with nucleic acids (either DNA or RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Structures Nucleoproteins tend to be positively charged, facilitating interaction with the negatively charged nucleic acid chains. The tertiary structures and biological functions of many nucleoproteins are understood.Graeme K. Hunter G. K. (2000): Vital Forces. The discovery of the molecular basis of life. Academic Press, London 2000, . Important techniques for determining the structures of nucleoproteins include X-ray diffraction, nuclear magnetic resonance and cryo-electron microscopy. Viruses Virus genomes (either DNA or RNA) are extremely tightly packed into the viral capsid. Many viruses are therefore little more than an organised collection of nucleoproteins with their binding sites pointing inwards. Structurally characterised viral nucleoproteins include influenza, rabies, Ebola, Bunyamwera, Schmallen ...
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Sclerodermataceae
The Sclerodermataceae are a family of fungi in the order Boletales, containing several genera of unusual fungi that little resemble boletes. Taxa, which include species commonly known as the ‘hard-skinned puffballs’, ‘earthballs’, or 'earthstars', are widespread in both temperate and tropical regions. The best known members include the earthball ''Scleroderma citrinum'', the dye fungus ''Pisolithus tinctorius'' and the ' prettymouths' of the genus ''Calostoma''. Description Fruit-bodies are mostly epigenous (above ground), rarely hypogeous (underground), more or less spherical in shape, without a stem or with an irregular root-like stem. The peridium (outer wall) is mostly simple, rarely 2-layered, firm, rarely thin, membranous, breaking open irregularly or in lobes or decaying, revealing the gleba. The gleba typically has sharply defined basidia-bearing sectors, which are partitioned from one another by sterile veins, and in which the basidia are regularly scattered throu ...
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