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Nikolay Gamaleya
Nikolay Fyodorovich Gamaleya (russian: Никола́й Фёдорович Гамале́я; – 29 March 1949) was a Russian and Soviet physician and scientist who played a pioneering role in microbiology and vaccine research. Biography Gamaleya was born in Odessa, then part of the Russian Empire. He graduated from Odessa's Novorossiysky University (now Odessa University) in 1880 and the St. Petersburg Military Medical Academy (now the S.M. Kirov Military Medical Academy) in 1883. He became a respected hospital physician in his native Odessa afterward. Gamaleya worked in Louis Pasteur's laboratory in France in 1886. Following Pasteur's model after his return, he joined Ilya Mechnikov in organizing an Odessa bacteriological station for rabies vaccination studies and research on combating cattle plague and cholera, diagnosing sputum for tuberculosis, and preparing anthrax vaccines.Zalkind, Semyon (2001). ''Ilya Mechnikov: His Life and Work''. Honolulu, Hawaii: University Press of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louse
Louse ( : lice) is the common name for any member of the clade Phthiraptera, which contains nearly 5,000 species of wingless parasitic insects. Phthiraptera has variously been recognized as an order, infraorder, or a parvorder, as a result of developments in phylogenetic research. Lice are obligate parasites, living externally on warm-blooded hosts which include every species of bird and mammal, except for monotremes, pangolins, and bats. Lice are vectors of diseases such as typhus. Chewing lice live among the hairs or feathers of their host and feed on skin and debris, while sucking lice pierce the host's skin and feed on blood and other secretions. They usually spend their whole life on a single host, cementing their eggs, called nits, to hairs or feathers. The eggs hatch into nymphs, which moult three times before becoming fully grown, a process that takes about four weeks. Genetic evidence indicates that lice are a highly modified lineage of Psocoptera (now called Ps ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plague (disease)
Plague is an infectious disease caused by the bacterium ''Yersinia pestis''. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms. Pneumonic plague infects the lungs, causing shortness of breath, coughing and chest pain; bubonic plague affects the lymph nodes, making them swell; and septicemic plague infects the blood and can cause tissues to turn black and die. The bubonic and septicemic forms are generally spread by flea bites or handling an infected animal, whereas pneumonic plague is generally spread between people through the air via infectious droplets. Diagnosis is typically by finding the bacterium in fluid from a lymph node, blood or sputum. Those at high risk may be vaccinated. Those exposed to a case of pneumonic plague may be treated with preventive medication. If infected, treatment is with antibiotic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Martin Center For Nonproliferation Studies
The Middlebury Institute of International Studies at Monterey (MIIS), formerly known as the Monterey Institute of International Studies, is an American graduate school of Middlebury College, a private college in Middlebury, Vermont. Established in 1955, the school provides instruction on a campus in Monterey, California. The institute offers a wide range of master's programs and certificates in various disciplines such as environmental policy, international policy, language teaching, and translation and interpretation. MIIS has two graduate professional schools known as the Graduate School of Translation, Interpretation, and Language Education (GSTILE) and the Graduate School of International Policy and Management (GSIPM), and several related centers. History Founding and expansion The Middlebury Institute was established in 1955 as the Monterey Institute for Foreign Studies (MIFS). In 1961, the school moved to its current downtown Monterey location, where it has since occupie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteriolysin
One of the serum substances which is part of the dissolution process of bacteria, the enzymes will promote the dissolution of the bacterial cell wall and cause the death of the bacteria. Bacteriolysin probably functions by deregulating lipoteichoic acid (LTA) in Gram-positive bacteria and phospholipids in Gram-negative bacteria. See also * Immune system * Immunity * Polyclonal response Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of ... References * http://onlinelibrary.wiley.com/doi/10.1034/j.1600-0463.2002.1101101.x/abstract;jsessionid=C40F7DA658C09C4F8491ACD72F89E9B7.f04t04 {{immune_system Immune system Cell biology Bacteriology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacillus Anthracis
''Bacillus anthracis'' is a gram-positive and rod-shaped bacterium that causes anthrax, a deadly disease to livestock and, occasionally, to humans. It is the only permanent ( obligate) pathogen within the genus ''Bacillus''. Its infection is a type of zoonosis, as it is transmitted from animals to humans. It was discovered by a German physician Robert Koch in 1876, and became the first bacterium to be experimentally shown as a pathogen. The discovery was also the first scientific evidence for the germ theory of diseases. ''B. anthracis'' measures about 3 to 5 μm long and 1 to 1.2 μm wide. The reference genome consists of a 5,227,419 bp circular chromosome and two extrachromosomal DNA plasmids, pXO1 and pXO2, of 181,677 and 94,830 bp respectively, which are responsible for the pathogenicity. It forms a protective layer called endospore by which it can remain inactive for many years and suddenly becomes infective under suitable environmental conditions. Because of the resilie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lysis
Lysis ( ) is the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic" ) mechanisms that compromise its integrity. A fluid containing the contents of lysed cells is called a ''lysate''. In molecular biology, biochemistry, and cell biology laboratories, cell cultures may be subjected to lysis in the process of purifying their components, as in protein purification, DNA extraction, RNA extraction, or in purifying organelles. Many species of bacteria are subject to lysis by the enzyme lysozyme, found in animal saliva, egg white, and other secretions. Phage lytic enzymes (lysins) produced during bacteriophage infection are responsible for the ability of these viruses to lyse bacterial cells. Penicillin and related β-lactam antibiotics cause the death of bacteria through enzyme-mediated lysis that occurs after the drug causes the bacterium to form a defective cell wall. If the cell wall is completely lost and the penicillin was used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Etiology
Etiology (pronounced ; alternatively: aetiology or ætiology) is the study of causation or origination. The word is derived from the Greek (''aitiología'') "giving a reason for" (, ''aitía'', "cause"); and ('' -logía''). More completely, etiology is the study of the causes, origins, or reasons behind the way that things are, or the way they function, or it can refer to the causes themselves. The word is commonly used in medicine (pertaining to causes of disease) and in philosophy, but also in physics, psychology, government, geography, spatial analysis, theology, and biology, in reference to the causes or origins of various phenomena. In the past, when many physical phenomena were not well understood or when histories were not recorded, myths often arose to provide etiologies. Thus, an etiological myth, or origin myth, is a myth that has arisen, been told over time or written to explain the origins of various social or natural phenomena. For example, Virgil's ''Aeneid'' is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chernigov
Chernihiv ( uk, Черні́гів, , russian: Черни́гов, ; pl, Czernihów, ; la, Czernihovia), is a List of cities in Ukraine, city and List of hromadas of Ukraine, municipality in northern Ukraine, which serves as the administrative center of Chernihiv Oblast and Chernihiv Raion within the oblast. Chernihiv's population is The city was designated as a Hero City of Ukraine, Hero City during the 2022 Russian invasion of Ukraine, 2022 Russian Invasion of Ukraine. Geography Chernihiv stands on the Desna River to the north-north-east of Kyiv. The area was served by Chernihiv Shestovitsa Airport, Chernihiv Shestovytsia Airport prior to 2002, and during the Cold War it was the site of Chernihiv (air base), Chernihiv air base. History Etymology The name "Chernihiv" is a compound name, which begins with the root 'Cherni/Cherno,' which means "black" in Slavic. Scholars vary with interpretations of the second part of the name ("hiv"/gov", "говъ") though scholars suc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yekaterinoslav
Dnipro, previously called Dnipropetrovsk from 1926 until May 2016, is Ukraine's fourth-largest city, with about one million inhabitants. It is located in the eastern part of Ukraine, southeast of the Ukrainian capital Kyiv on the Dnieper River, after which its Ukrainian language name (Dnipro) it is named. Dnipro is the administrative centre of the Dnipropetrovsk Oblast. It hosts the administration of Dnipro urban hromada. The population of Dnipro is Archeological evidence suggests the site of the present city was settled by Cossack communities from at least 1524. The town, named Yekaterinoslav (''the glory of Catherine''), was established by decree of the Russian Empress Catherine the Great in 1787 as the administrative center of Novorossiya. From the end of the nineteenth century, the town attracted foreign capital and an international, multi-ethnic, workforce exploiting Kryvbas iron ore and Donbas coal. Renamed ''Dnipropetrovsk'' in 1926 after the Ukrainian Communist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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