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Nummular Keratitis
Nummular keratitis is a feature of viral keratoconjunctivitis. It is a common feature of adenoviral keratoconjunctivitis (an ocular adenovirus infection), as well as approximately 1/3rd of cases of Herpes Zoster Ophthalmicus infections. It represents the presence of anterior stromal infiltrates. Unilateral or bilateral subepithelial lesions of the cornea The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power ... may be present. Slit lamp examination reveals multiple tiny granular deposits surrounded by a halo of stromal haze. After healing, residual 'nummular scars' often remain. Disciform keratitis occurs in 50% of individuals with Nummular keratitis, but Nummular keratitis always precedes Disciform keratitis. Treatment * Topical NSAIDS * Lubricating eye drops * Topical dilute steroid d ...
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Nummular Keratitis 1
Nummular means something coin-shaped, such as: *Nummular dermatitis Nummular dermatitis is one of the many forms of dermatitis. it is characterized by round or oval-shaped itchy lesions. The name comes from the Latin word " nummus," which means "coin." Signs and symptoms Nummular dermatitis is characterized by chr ... * Nummular psoriasis {{disambig ...
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Keratoconjunctivitis
Keratoconjunctivitis is inflammation ("-itis") of the cornea and conjunctiva. When only the cornea is inflamed, it is called ''keratitis''; when only the conjunctiva is inflamed, it is called ''conjunctivitis''. Causes There are several potential causes of the inflammation: * Keratoconjunctivitis sicca is used when the inflammation is due to dryness. ("Sicca" means "dryness" in medical contexts.) It occurs with 20% of rheumatoid arthritis patients. * The term " vernal keratoconjunctivitis" (VKC) is used to refer to keratoconjunctivitis occurring in spring, and is usually considered to be due to allergens. * "Atopic keratoconjunctivitis" is one manifestation of atopy. * "Epidemic keratoconjunctivitis" is caused by an adenovirus infection. * " Infectious bovine keratoconjunctivitis" (IBK) is a disease affecting cattle caused by the bacteria '' Moraxella bovis''. * "Pink eye in sheep and goat" is another infectious keratoconjunctivitis of veterinary concern, mostly caused by '' Chl ...
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Adenoviral Keratoconjunctivitis
Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by ''adenoviruses''. It typically presents as a conjunctivitis with a sudden onset of a painful red eye, watery discharge and feeling that something is in the eye. Photophobia develops with blurred vision and lymphadenopathy by the ear nearest the affected eye. It is often associated with a sore throat and stuffy and runny nose, mainly in adults. A type of adenoviral keratoconjunctivitis in very young children can present with a high fever, sore throat, ear infection, vomiting and diarrhea. It is commonly caused by types 8 and 37 ''adenoviruses'', spread by contaminated eye examination instruments and eye solutions, touching eyes by infected people, from inadequately chlorinated swimming pools, or other contaminated objects. The incubation period is around five to 10 days. Usually, the condition is better after a week to 10-days with ...
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Adenoviridae
Adenoviruses (members of the family ''Adenoviridae'') are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. Virology Classification This family contains the following genera: * '' Atadenovirus'' * '' Aviadenovirus'' * '' Ichtadenovirus'' * '' Mastadenovirus'' (including all human adenoviruses) * '' Siadenovirus'' * '' Testadenovirus'' Diversity In humans, currently there are 88 human adenoviruses (HAdVs) in seven species (Human adenovirus A to G): * A: 12, 18, 31 * B: 3, 7, 11, 14, ...
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Ophthalmic Zoster
Herpes zoster ophthalmicus (HZO), also known as ophthalmic zoster, is shingles involving the eye or the surrounding area. Common signs include a rash of the forehead with swelling of the eyelid. There may also be eye pain and redness, inflammation of the conjunctiva, cornea or uvea, and sensitivity to light. Fever and tingling of the skin and allodynia near the eye may precede the rash. Complications may include visual impairment, increased pressure within the eye, chronic pain, and stroke. The underlying mechanism involves a reactivation of the latent varicella zoster virus (VZV) within the trigeminal ganglion supplying the ophthalmic nerve (the first division of the trigeminal nerve). Diagnosis is generally based on signs and symptoms. Alternatively, fluid collected from the rash may be analyzed for VZV DNA using real-time PCR. This test is rapid, easy to perform, and is highly sensitive and specific method for diagnosing this condition. Treatment is generally wit ...
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Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is approximately 43 dioptres. The cornea can be reshaped by surgical procedures such as LASIK. While the cornea contributes most of the eye's focusing power, its focus is fixed. Accommodation (the refocusing of light to better view near objects) is accomplished by changing the geometry of the lens. Medical terms related to the cornea often start with the prefix "'' kerat-''" from the Greek word κέρας, ''horn''. Structure The cornea has unmyelinated nerve endings sensitive to touch, temperature and chemicals; a touch of the cornea causes an involuntary reflex to close the eyelid. Because transparency is of prime importance, the healthy cornea does not have or need blood vessels with ...
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Herpes Simplex Keratitis
Herpetic simplex keratitis is a form of keratitis caused by recurrent herpes simplex virus (HSV) infection in the cornea. It begins with infection of epithelial cells on the surface of the eye and retrograde infection of nerves serving the cornea. Primary infection typically presents as swelling of the conjunctiva and eyelids (blepharoconjunctivitis), accompanied by small white itchy lesions on the corneal surface. The effect of the lesions varies, from minor damage to the epithelium ( superficial punctate keratitis), to more serious consequences such as the formation of dendritic ulcers. Infection is unilateral, affecting one eye at a time. Additional symptoms include dull pain deep inside the eye, mild to acute dryness, and sinusitis. Most primary infections resolve spontaneously in a few weeks. Healing can be aided by the use of oral and topical antivirals. Subsequent recurrences may be more severe, with infected epithelial cells showing larger dendritic ulceration, and lesi ...
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Adenoviral Keratoconjunctivitis
Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by ''adenoviruses''. It typically presents as a conjunctivitis with a sudden onset of a painful red eye, watery discharge and feeling that something is in the eye. Photophobia develops with blurred vision and lymphadenopathy by the ear nearest the affected eye. It is often associated with a sore throat and stuffy and runny nose, mainly in adults. A type of adenoviral keratoconjunctivitis in very young children can present with a high fever, sore throat, ear infection, vomiting and diarrhea. It is commonly caused by types 8 and 37 ''adenoviruses'', spread by contaminated eye examination instruments and eye solutions, touching eyes by infected people, from inadequately chlorinated swimming pools, or other contaminated objects. The incubation period is around five to 10 days. Usually, the condition is better after a week to 10-days with ...
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Ophthalmology
Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medical degree, a doctor specialising in ophthalmology must pursue additional postgraduate residency training specific to that field. This may include a one-year integrated internship that involves more general medical training in other fields such as internal medicine or general surgery. Following residency, additional specialty training (or fellowship) may be sought in a particular aspect of eye pathology. Ophthalmologists prescribe medications to treat eye diseases, implement laser therapy, and perform surgery when needed. Ophthalmologists provide both primary and specialty eye care - medical and surgical. Most ophthalmologists participate in academic research on eye diseases at some point in their training and many include research as part ...
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