Norsecurinine
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Norsecurinine
Norsecurinine is a securinega alkaloid from ''Phyllanthus niruri''. See also * Securinine Securinine is an alkaloid found in ''Securinega suffruticosa'' and ''Phyllanthus niruri''. Pharmacology Securinine has pro-convulsant effects and it has a strong Spasticity, spastic effect, similar to the actions of strychnine. Securinine is ... References {{Reflist Alkaloids Tetracyclic compounds Nitrogen heterocycles Lactones Furanones Cyclohexenes ...
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Securinine
Securinine is an alkaloid found in ''Securinega suffruticosa'' and ''Phyllanthus niruri''. Pharmacology Securinine has pro-convulsant effects and it has a strong Spasticity, spastic effect, similar to the actions of strychnine. Securinine is a GABA-A antagonist. See also * Norsecurinine * Phenazine References

{{Reflist Tetracyclic compounds Nitrogen heterocycles Lactones Alkaloids Furanones Cyclohexenes Withdrawn drugs ...
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Securinega Alkaloid
''Securinega'' is a genus of plants in the family Phyllanthaceae, first described as a genus in 1789. As presently conceived, the genus is native to Madagascar and the Mascarene Islands in the Indian Ocean. In the past, it was considered to be much more widespread, thus explaining the long list of species formerly included. It is dioecious, with male and female flowers on separate plants. ;Species # '' Securinega antsingyensis'' Leandri - W Madagascar # '' Securinega capuronii'' Leandri - W Madagascar # ''Securinega durissima'' J.F.Gmel. - Madagascar, Mauritius, Réunion, Rodrigues Island # ''Securinega perrieri'' Leandri - W Madagascar # '' Securinega seyrigii'' Leandri - W Madagascar ;Formerly included moved to other genera ''(Actephila Andrachne Chascotheca Cleistanthus Flueggea Jablonskia Margaritaria Meineckia Neoroepera ''Neoroepera'' is a genus of plants in the Picrodendraceae first described as a genus in 1866. The entire genus is endemic to the State of Queensland in ...
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Phyllanthus Niruri
''Phyllanthus niruri'' is a widespread tropical plant commonly found in coastal areas, known by the common names gale of the wind, stonebreaker, shatter stone , seed-under-leaf, quebra pedra and chance pierre. It is in the genus ''Phyllanthus'' of the family Phyllanthaceae. Description It grows tall and bears ascending herbaceous branches. The bark is smooth and light green. It bears numerous pale green flowers which are often flushed with red. The fruits are tiny, smooth capsules containing seeds. Research A 2011 Cochrane review found that there is "no convincing evidence that phyllanthus, compared with placebo, benefits patients with chronic HBV (hepatitis B virus ''Hepatitis B virus'' (HBV) is a partially double-stranded DNA virus, a species of the genus ''Orthohepadnavirus'' and a member of the ''Hepadnaviridae'' family of viruses. This virus causes the disease hepatitis B. Disease Despite there bein ...) infection." Gallery Image:Keezharnelli_new.jpg, Niruri fr ...
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Alkaloids
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , ,

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Tetracyclic Compounds
Tetracyclics are cyclic chemical compounds that contain four interconnected rings of atoms, e.g. Tröger's base. They have various pharmaceutical uses, for instance the tetracycline antibiotics and the tetracyclic antidepressants. See also * Tricyclic * Heterocyclic A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and ... References {{Reflist Tetracyclic compounds ...
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Nitrogen Heterocycles
Nitrogen is the chemical element with the symbol N and atomic number 7. Nitrogen is a nonmetal and the lightest member of group 15 of the periodic table, often called the pnictogens. It is a common element in the universe, estimated at seventh in total abundance in the Milky Way and the Solar System. At standard temperature and pressure, two atoms of the element bond to form N2, a colorless and odorless diatomic gas. N2 forms about 78% of Earth's atmosphere, making it the most abundant uncombined element. Nitrogen occurs in all organisms, primarily in amino acids (and thus proteins), in the nucleic acids ( DNA and RNA) and in the energy transfer molecule adenosine triphosphate. The human body contains about 3% nitrogen by mass, the fourth most abundant element in the body after oxygen, carbon, and hydrogen. The nitrogen cycle describes the movement of the element from the air, into the biosphere and organic compounds, then back into the atmosphere. Many industrially importa ...
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Lactones
Lactones are cyclic carboxylic esters, containing a 1-oxacycloalkan-2-one structure (), or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. Lactones are formed by intramolecular esterification of the corresponding hydroxycarboxylic acids, which takes place spontaneously when the ring that is formed is five- or six-membered. Lactones with three- or four-membered rings (α-lactones and β-lactones) are very reactive, making their isolation difficult. Special methods are normally required for the laboratory synthesis of small-ring lactones as well as those that contain rings larger than six-membered. Nomenclature Lactones are usually named according to the precursor acid molecule (''aceto'' = 2 carbon atoms, ''propio'' = 3, ''butyro'' = 4, ''valero'' = 5, ''capro'' = 6, etc.), with a ''-lactone'' suffix and a Greek letter prefix that specifies the number of carbon atoms in the heterocycle — that is, the distance between the relevant -OH ...
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