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Nonivamide
Nonivamide, also called pelargonic acid vanillylamide or PAVA, is an organic compound and a capsaicinoid. It is an amide of pelargonic acid (n-nonanoic acid) and vanillyl amine. It is present in chili peppers, but is commonly manufactured synthetically. It is more heat-stable than capsaicin. Nonivamide is used as a food additive to add pungency to seasonings, flavorings, and spice blends. It is also used in the confectionery industry to create a hot sensation, and in the pharmaceutical industry in some formulations as a cheaper alternative to capsaicin. Like capsaicin, it can deter mammals (but not birds or insects) from consuming plants or seeds (e.g. squirrels and bird feeder seeds).http://www.aversiontech.com/hot-and-spicy/nonivamide-pava/Retrieved 16 July 2010 This is consistent with nonivamide's role as a TRPV1 ion channel agonist. Mammalian TRPV1 is activated by heat and capsaicin, but the avian form is insensitive to capsaicin. Nonivamide is used (under the name PAV ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capsaicinoids
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) ( or ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a chemical irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related alkaloids are called capsaicinoids and are produced as secondary metabolites by chili peppers, probably as deterrents against certain mammals and fungi.What Made Chili Peppers So Spicy? Talk of the Nation, 15 August 2008. Pure capsaicin is a , colorless, highly |
Capsaicinoid
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) ( or ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a chemical irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related alkaloids are called capsaicinoids and are produced as secondary metabolites by chili peppers, probably as deterrents against certain mammals and fungi.What Made Chili Peppers So Spicy? Talk of the Nation, 15 August 2008. Pure capsaicin is a , colorless, highly |
Capsaicin
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) ( or ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a chemical irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related alkaloids are called capsaicinoids and are produced as secondary metabolites by chili peppers, probably as deterrents against certain mammals and fungi.What Made Chili Peppers So Spicy? Talk of the Nation, 15 August 2008. Pure capsaicin is a , colorless, highly |
PAVA Spray
PAVA spray is an incapacitant spray similar to pepper spray. It is dispensed from a handheld canister, in a liquid stream. It contains a 0.3% solution of pelargonic acid vanillylamide (PAVA), also called nonivamide, a synthetic capsaicinoid (analogue of capsaicin), in a solvent of aqueous ethanol. The propellant is nitrogen. This solution has been selected because this is the minimum concentration which will fulfill the purpose of the equipment; namely to minimise a person's capacity for resistance, without unnecessarily prolonging their discomfort. PAVA is significantly more potent than CS gas. The liquid stream is a spray pattern and has a maximum effective range of up to . Maximum accuracy, however, will be achieved over a distance of . The operating distance is the distance between the canister and the subject's eyes, not the distance between the user and the subject. Effects PAVA primarily affects the eyes, causing closure and severe pain. The pain to the eyes is reported to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Riot Control
Riot control measures are used by law enforcement, military, paramilitary or security forces to control, disperse, and arrest people who are involved in a riot, unlawful demonstration or unlawful protest. If a riot is spontaneous and irrational, actions which cause people to stop and think for a moment (e.g. loud noises or issuing instructions in a calm tone) can be enough to stop it. However, these methods usually fail when there is severe anger with a legitimate cause, or the riot was planned or organized. Riot control personnel have long used less lethal weapons such as batons and whips to disperse crowds and detain rioters. Since the 1980s, riot control officers have also used tear gas, pepper spray, rubber bullets, stun grenades, and electric tasers. In some cases, riot squads may also use Long Range Acoustic Devices, water cannons, armoured fighting vehicles, aerial surveillance, police dogs or mounted police on horses. Persons performing riot control typically wear p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pepper Spray
Pepper spray, oleoresin capsicum spray, OC spray, capsaicin spray, or capsicum spray is a lachrymatory agent (a compound that irritates the eyes to cause a burning sensation, pain, and temporary blindness) used in policing, riot control, crowd control, and self-defense, including defense against dogs and bears. Its inflammatory effects cause the eyes to close, temporarily taking away vision. This temporary blindness allows officers to more easily restrain subjects and permits people in danger to use pepper spray in self-defense for an opportunity to escape. It also causes temporary discomfort and burning of the lungs which causes shortness of breath. Pepper spray was engineered into a spray originally for defense against bears, mountain lions, wolves and other dangerous predators, and is often referred to colloquially as bear spray. Kamran Loghman, the person who developed it for use in riot control, wrote the guide for police departments on how it should be used. It was s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FN 303
The FN 303 is a semi-automatic less-lethal riot gun designed and manufactured by Fabrique Nationale de Herstal. The FN 303 uses compressed air to fire projectiles from a 15-round drum magazine. It is designed to incapacitate the target through blunt trauma without causing critical injuries, and is most widely used for riot control and other kinds of combat where lethal weapons should be avoided. The 303 can be fired from the shoulder using adjustable iron sights, or it can be mounted in an under-barrel configuration on most assault rifles when its stock assembly is removed (in this configuration, it is designated ''M303''). It also comes with a top-mounted Picatinny rail that can fit most commercial weapon accessories, such as telescopic sights, laser sights and tactical lights. FN markets its own set of accessories for the launcher, including tactical vests, slings, carrying bags, and gas compressors. It is accurate at distances up to . FN also produce a pistol variant, the FN ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lachrymatory Agents
Lachrymatory or lacrymatory may refer to: * Something that has the effect of ''lachrymation'', causing the secretion of tears * Tear gas Tear gas, also known as a lachrymator agent or lachrymator (), sometimes colloquially known as "mace" after the early commercial aerosol, is a chemical weapon that stimulates the nerves of the lacrimal gland in the eye to produce tears. In ad ..., known formally as a ''lachrymatory agent'' or ''lachrymator'' * A lacrymatory, a small vessel of terracotta or glass found in Roman and late Greek tombs, thought to have been used to collect the tears of mourners at funerals {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Riot Control Agents
A riot is a form of civil disorder commonly characterized by a group lashing out in a violent public disturbance against authority, property, or people. Riots typically involve destruction of property, public or private. The property targeted varies depending on the riot and the inclinations of those involved. Targets can include shops, cars, restaurants, state-owned institutions, and religious buildings. Riots often occur in reaction to a grievance or out of dissent. Historically, riots have occurred due to poverty, unemployment, poor living conditions, governmental oppression, taxation or conscription, conflicts between ethnic groups (race riot) or religions (sectarian violence, pogrom), the outcome of a sporting event (sports riot, football hooliganism) or frustration with legal channels through which to air grievances. While individuals may attempt to lead or control a riot, riots typically consist of disorganized groups that are frequently "chaotic and exhibit herd beha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylacetylrinvanil
Phenylacetylrinvanil (IDN-5890) is a synthetic analogue of capsaicin which acts as a potent and selective agonist for the TRPV1 receptor, with slightly lower potency than resiniferatoxin, though still around 300 times the potency of capsaicin. It is an amide of vanillylamine and ricinoleic acid, with the hydroxyl group on ricinoleic acid esterified with phenylacetic acid Phenylacetic acid (PAA; conjugate base phenylacetate), also known by various synonyms, is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a strong honey-like odor. Endogen .... It is used to study the function of the TRPV1 receptor and its downstream actions, and has also shown anti-cancer effects ''in vitro''. References Capsaicinoids {{pharm-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blepharospasm
Blepharospasm is any abnormal contraction of the orbicularis oculi muscle. The condition should be distinguished from the more common, and milder, involuntary quivering of an eyelid, known as myokymia, or fasciculation. In most cases, blepharospasm symptoms last for a few days and then disappear without treatment, but in some cases the twitching is chronic and persistent, causing life-long challenges. In these cases, the symptoms are often severe enough to result in functional blindness. The person's eyelids feel like they are clamping shut and will not open without great effort. People have normal eyes, but for periods of time are effectively blind due to their inability to open their eyelids. In contrast, the reflex blepharospasm is due to any pain in and around the eye. It is of two types: essential and reflex blepharospasm. The benign essential blepharospasm (BEB) is a focal dystonia—a neurological movement disorder involving involuntary and sustained contractions of the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lacrimation
Tears are a clear liquid secreted by the lacrimal glands (tear gland) found in the eyes of all land mammals. Tears are made up of water, electrolytes, proteins, lipids, and mucins that form layers on the surface of eyes. The different types of tears—basal, reflex, and emotional—vary significantly in composition. The functions of tears include lubricating the eyes (basal tears), removing irritants (reflex tears), and also aiding the immune system. Tears also occur as a part of the body's natural pain response. Emotional secretion of tears may serve a biological function by excreting stress-inducing hormones built up through times of emotional distress. Tears have symbolic significance among humans. Physiology Chemical composition Tears are made up of three layers: lipid, aqueous, and mucous. Tears are composed of water, salts, antibodies, and lysozymes (antibacterial enzymes); though composition varies among different tear types. The composition of tears caused by an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
